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Adjuvant statin therapy for oesophageal adenocarcinoma: the STAT-ROC feasibility study.

Alexandre L, Clark AB, Walton S, Lewis MP, Kumar B, Cheong EC, Warren H, Kadirkamanathan SS, Parsons SL, Dresner SM, Sims E, Jones M, Hammond M, Flather M, Loke YK, Swart AM, Hart AR.

BJS Open. 2020 Feb;4(1):59-70. doi: 10.1002/bjs5.50239. Epub 2019 Dec 14.


Association between different methods of assessing blood pressure variability and incident cardiovascular disease, cardiovascular mortality and all-cause mortality: a systematic review.

Smith TO, Sillito JA, Goh CH, Abdel-Fattah AR, Einarsson A, Soiza RL, Mamas MA, Tan MP, Potter JF, Loke YK, Myint PK.

Age Ageing. 2020 Jan 27. pii: afz178. doi: 10.1093/ageing/afz178. [Epub ahead of print]


Continuous glucose monitoring in older people with diabetes and memory problems: a mixed-methods feasibility study in the UK.

Mattishent K, Lane K, Salter C, Dhatariya K, May HM, Neupane S, Loke YK.

BMJ Open. 2019 Nov 18;9(11):e032037. doi: 10.1136/bmjopen-2019-032037.


Anticholinergic and benzodiazepine medication use and risk of incident dementia: a UK cohort study.

Grossi CM, Richardson K, Fox C, Maidment I, Steel N, Loke YK, Arthur A, Myint PK, Campbell N, Boustani M, Robinson L, Brayne C, Matthews FE, Savva GM.

BMC Geriatr. 2019 Oct 21;19(1):276. doi: 10.1186/s12877-019-1280-2.


Interventions to Reduce Anticholinergic Burden in Adults Aged 65 and Older: A Systematic Review.

Nakham A, Myint PK, Bond CM, Newlands R, Loke YK, Cruickshank M.

J Am Med Dir Assoc. 2020 Feb;21(2):172-180.e5. doi: 10.1016/j.jamda.2019.06.001. Epub 2019 Jul 24. Review.


The development of search filters for adverse effects of medical devices in medline and embase.

Golder S, Farrah K, Mierzwinski-Urban M, Wright K, Loke YK.

Health Info Libr J. 2019 Sep;36(3):244-263. doi: 10.1111/hir.12260. Epub 2019 Jun 11.


Overview: comprehensive and carefully constructed strategies are required when conducting searches for adverse effects data.

Golder S, Peryer G, Loke YK.

J Clin Epidemiol. 2019 Sep;113:36-43. doi: 10.1016/j.jclinepi.2019.05.019. Epub 2019 May 28.


History of Benzodiazepine Prescriptions and Risk of Dementia: Possible Bias Due to Prevalent Users and Covariate Measurement Timing in a Nested Case-Control Study.

Richardson K, Mattishent K, Loke YK, Steel N, Fox C, Grossi CM, Bennett K, Maidment I, Boustani M, Matthews FE, Myint PK, Campbell NL, Brayne C, Robinson L, Savva GM.

Am J Epidemiol. 2019 Jul 1;188(7):1228-1236. doi: 10.1093/aje/kwz073.


The effects of hypoglycaemia and dementia on cardiovascular events, falls and fractures and all-cause mortality in older individuals: A retrospective cohort study.

Mattishent K, Richardson K, Dhatariya K, Savva GM, Fox C, Loke YK.

Diabetes Obes Metab. 2019 Sep;21(9):2076-2085. doi: 10.1111/dom.13769. Epub 2019 Jun 12.


Hepatic late adverse effects after antineoplastic treatment for childhood cancer.

Mulder RL, Bresters D, Van den Hof M, Koot BG, Castellino SM, Loke YKK, Post PN, Postma A, Szőnyi LP, Levitt GA, Bardi E, Skinner R, van Dalen EC.

Cochrane Database Syst Rev. 2019 Apr 15;4:CD008205. doi: 10.1002/14651858.CD008205.pub3.


Dietary components and risk of cardiovascular disease and all-cause mortality: a review of evidence from meta-analyses.

Kwok CS, Gulati M, Michos ED, Potts J, Wu P, Watson L, Loke YK, Mallen C, Mamas MA.

Eur J Prev Cardiol. 2019 Sep;26(13):1415-1429. doi: 10.1177/2047487319843667. Epub 2019 Apr 11.


Effectiveness of 80% vs 30-35% fraction of inspired oxygen in patients undergoing surgery: an updated systematic review and meta-analysis.

de Jonge S, Egger M, Latif A, Loke YK, Berenholtz S, Boermeester M, Allegranzi B, Solomkin J.

Br J Anaesth. 2019 Mar;122(3):325-334. doi: 10.1016/j.bja.2018.11.024. Epub 2019 Jan 6.


Safety of 80% vs 30-35% fraction of inspired oxygen in patients undergoing surgery: a systematic review and meta-analysis.

Mattishent K, Thavarajah M, Sinha A, Peel A, Egger M, Solomkin J, de Jonge S, Latif A, Berenholtz S, Allegranzi B, Loke YK.

Br J Anaesth. 2019 Mar;122(3):311-324. doi: 10.1016/j.bja.2018.11.026. Epub 2019 Jan 3.


Nonspecific Chest Pain and 30-Day Unplanned Readmissions in the United States (From the Nationwide Readmission Database).

Kwok CS, Parwani PJ, Fischman DL, Thamman R, Suwaidi JA, Mohamed M, Borovac JA, Loke YK, Kontopantelis E, Brown DL, Mamas MA.

Am J Cardiol. 2019 Apr 15;123(8):1343-1350. doi: 10.1016/j.amjcard.2019.01.012. Epub 2019 Jan 25.


Self-Reported Sleep Duration and Quality and Cardiovascular Disease and Mortality: A Dose-Response Meta-Analysis.

Kwok CS, Kontopantelis E, Kuligowski G, Gray M, Muhyaldeen A, Gale CP, Peat GM, Cleator J, Chew-Graham C, Loke YK, Mamas MA.

J Am Heart Assoc. 2018 Aug 7;7(15):e008552. doi: 10.1161/JAHA.118.008552.


Oral direct-acting antivirals and the incidence or recurrence of hepatocellular carcinoma: a systematic review and meta-analysis.

Singh S, Nautiyal A, Loke YK.

Frontline Gastroenterol. 2018 Oct;9(4):262-270. doi: 10.1136/flgastro-2018-101017. Epub 2018 Jul 30.


Effect of Antiplatelet Therapy (Aspirin + Dipyridamole Versus Clopidogrel) on Mortality Outcome in Ischemic Stroke.

Barlas RS, Loke YK, Mamas MA, Bettencourt-Silva JH, Ford I, Clark AB, Bowles KM, Metcalf AK, Potter JF, Myint PK.

Am J Cardiol. 2018 Sep 15;122(6):1085-1090. doi: 10.1016/j.amjcard.2018.05.043. Epub 2018 Jul 30.


Detection of asymptomatic drug-induced hypoglycemia using continuous glucose monitoring in older people - Systematic review.

Mattishent K, Loke YK.

J Diabetes Complications. 2018 Aug;32(8):805-812. doi: 10.1016/j.jdiacomp.2018.05.005. Epub 2018 May 18.


Asthma Breathomics and Biomedium Consideration.

Peel AM, Loke YK, Wilson AM.

Chest. 2018 May;153(5):1283. doi: 10.1016/j.chest.2018.02.029. No abstract available.


Anticholinergic drugs and risk of dementia: case-control study.

Richardson K, Fox C, Maidment I, Steel N, Loke YK, Arthur A, Myint PK, Grossi CM, Mattishent K, Bennett K, Campbell NL, Boustani M, Robinson L, Brayne C, Matthews FE, Savva GM.

BMJ. 2018 Apr 25;361:k1315. doi: 10.1136/bmj.k1315. Erratum in: BMJ. 2019 Oct 31;367:l6213.


The development of search filters for adverse effects of surgical interventions in medline and Embase.

Golder S, Wright K, Loke YK.

Health Info Libr J. 2018 Jun;35(2):121-129. doi: 10.1111/hir.12213. Epub 2018 Mar 31. Review.


Asthma breathomics-promising biomarkers in need of validation.

Peel AM, Wilson AM, Loke YK.

Pediatr Pulmonol. 2018 Mar;53(3):263-265. doi: 10.1002/ppul.23941. Epub 2018 Jan 23. No abstract available.


World Health Organization Responds to Concerns about Surgical Site Infection Prevention Recommendations.

Solomkin J, Egger M, de Jonge S, Latif A, Loke YK, Berenholtz S, Allegranzi B.

Anesthesiology. 2018 Jan;128(1):221-222. doi: 10.1097/ALN.0000000000001941. No abstract available.


Closure methods of the appendix stump for complications during laparoscopic appendectomy.

Mannu GS, Sudul MK, Bettencourt-Silva JH, Cumber E, Li F, Clark AB, Loke YK.

Cochrane Database Syst Rev. 2017 Nov 13;11:CD006437. doi: 10.1002/14651858.CD006437.pub3. Review.


Protocol for a feasibility randomised controlled trial of Screening and Enhanced Risk management for Vascular Event-related Decline in Memory (SERVED Memory).

Myint PK, Loke YK, Davison W, Mattishent K, Fox GC, Fleetcroft R, Turner D, Shepstone L, Potter JF.

BMJ Open. 2017 Nov 28;7(11):e017416. doi: 10.1136/bmjopen-2017-017416.


The feasibility of a search filter for the adverse effects of nondrug interventions in MEDLINE and Embase.

Golder S, Wright K, Loke YK.

Res Synth Methods. 2017 Dec;8(4):506-513. doi: 10.1002/jrsm.1267. Epub 2017 Oct 11.


Communication skills training for mental health professionals working with people with severe mental illness.

Papageorgiou A, Loke YK, Fromage M.

Cochrane Database Syst Rev. 2017 Jun 13;6:CD010006. doi: 10.1002/14651858.CD010006.pub2. Review.


Overview of systematic reviews of therapeutic ranges: methodologies and recommendations for practice.

Cooney L, Loke YK, Golder S, Kirkham J, Jorgensen A, Sinha I, Hawcutt D.

BMC Med Res Methodol. 2017 Jun 2;17(1):84. doi: 10.1186/s12874-017-0363-z. Review.


Strengths and limitations of healthcare databases in the evaluation of hypoglycaemia.

Loke YK, Mattishent K.

Diabetes Obes Metab. 2017 Oct;19(10):1337-1338. doi: 10.1111/dom.12984. Epub 2017 Jul 13. No abstract available.


Statistical reporting of clinical pharmacology research.

Ring A, Schall R, Loke YK, Day S.

Br J Clin Pharmacol. 2017 Jun;83(6):1159-1162. doi: 10.1111/bcp.13254. Epub 2017 Mar 21.


The effect of co-trimoxazole on serum potassium concentration: safety evaluation of a randomized controlled trial.

Chan WY, Clark AB, Wilson AM, Loke YK; TIPAC investigators.

Br J Clin Pharmacol. 2017 Aug;83(8):1808-1814. doi: 10.1111/bcp.13263. Epub 2017 Mar 20.


Important factors in predicting mortality outcome from stroke: findings from the Anglia Stroke Clinical Network Evaluation Study.

Myint PK, O Bachmann M, Loke YK, D Musgrave S, Price GM, Hale R, Metcalf AK, Turner DA, Day DJ, A Warburton E, Potter JF.

Age Ageing. 2017 Jan 28;46(1):83-90. doi: 10.1093/ageing/afw175.


Biomarkers in adult asthma: a systematic review of 8-isoprostane in exhaled breath condensate.

Peel AM, Crossman-Barnes CJ, Tang J, Fowler SJ, Davies GA, Wilson AM, Loke YK.

J Breath Res. 2017 Feb 10;11(1):016011. doi: 10.1088/1752-7163/aa5a8a. Review.


Diagnostic accuracy of motor evoked potentials to detect neurological deficit during idiopathic scoliosis correction: a systematic review.

Thirumala PD, Crammond DJ, Loke YK, Cheng HL, Huang J, Balzer JR.

J Neurosurg Spine. 2017 Mar;26(3):374-383. doi: 10.3171/2015.7.SPINE15466. Epub 2016 Dec 9. Review.


Incidentally Raised Cardiac Troponin I Has a Worse Prognosis in Older Patients Compared to Those with Normal Cardiac Troponin I and Patients with Acute Coronary Syndrome: A Cohort Study.

Mannu GS, Honney K, Spooner R, Clark AB, Bettencourt-Silva JH, Zaman MJ, Loke YK, Myint PK.

Gerontology. 2016;62(6):581-587. Epub 2016 Mar 24.


ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions.

Sterne JA, Hernán MA, Reeves BC, Savović J, Berkman ND, Viswanathan M, Henry D, Altman DG, Ansari MT, Boutron I, Carpenter JR, Chan AW, Churchill R, Deeks JJ, Hróbjartsson A, Kirkham J, Jüni P, Loke YK, Pigott TD, Ramsay CR, Regidor D, Rothstein HR, Sandhu L, Santaguida PL, Schünemann HJ, Shea B, Shrier I, Tugwell P, Turner L, Valentine JC, Waddington H, Waters E, Wells GA, Whiting PF, Higgins JP.

BMJ. 2016 Oct 12;355:i4919. doi: 10.1136/bmj.i4919. No abstract available.


Reporting of Adverse Events in Published and Unpublished Studies of Health Care Interventions: A Systematic Review.

Golder S, Loke YK, Wright K, Norman G.

PLoS Med. 2016 Sep 20;13(9):e1002127. doi: 10.1371/journal.pmed.1002127. eCollection 2016 Sep. Review.


Impact of Hemoglobin Levels and Anemia on Mortality in Acute Stroke: Analysis of UK Regional Registry Data, Systematic Review, and Meta-Analysis.

Barlas RS, Honney K, Loke YK, McCall SJ, Bettencourt-Silva JH, Clark AB, Bowles KM, Metcalf AK, Mamas MA, Potter JF, Myint PK.

J Am Heart Assoc. 2016 Aug 17;5(8). pii: e003019. doi: 10.1161/JAHA.115.003019. Review.


Methodological review: quality of randomized controlled trials in health literacy.

Brainard J, Wilsher SH, Salter C, Loke YK.

BMC Health Serv Res. 2016 Jul 11;16:246. doi: 10.1186/s12913-016-1479-2. Review.


Meta-Analysis of the Prognostic Impact of Anemia in Patients Undergoing Percutaneous Coronary Intervention.

Kwok CS, Tiong D, Pradhan A, Andreou AY, Nolan J, Bertrand OF, Curzen N, Urban P, Myint PK, Zaman AG, Loke YK, Mamas MA.

Am J Cardiol. 2016 Aug 15;118(4):610-20. doi: 10.1016/j.amjcard.2016.05.059. Epub 2016 May 29. Review.


Most systematic reviews of adverse effects did not include unpublished data.

Golder S, Loke YK, Wright K, Sterrantino C.

J Clin Epidemiol. 2016 Sep;77:125-133. doi: 10.1016/j.jclinepi.2016.05.003. Epub 2016 Jun 1.


Meta-analysis: Association between hypoglycaemia and serious adverse events in older patients.

Mattishent K, Loke YK.

J Diabetes Complications. 2016 Jul;30(5):811-8. doi: 10.1016/j.jdiacomp.2016.03.018. Epub 2016 Mar 17. Review.


Habitual chocolate consumption and the risk of incident heart failure among healthy men and women.

Kwok CS, Loke YK, Welch AA, Luben RN, Lentjes MA, Boekholdt SM, Pfister R, Mamas MA, Wareham NJ, Khaw KT, Myint PK.

Nutr Metab Cardiovasc Dis. 2016 Aug;26(8):722-34. doi: 10.1016/j.numecd.2016.01.003. Epub 2016 Jan 28. Review.


Diagnostic accuracy of somatosensory evoked potential monitoring during scoliosis fusion.

Thirumala PD, Cheng HL, Loke YK, Kojo Hamilton D, Balzer J, Crammond DJ.

J Clin Neurosci. 2016 Aug;30:8-14. doi: 10.1016/j.jocn.2016.01.017. Epub 2016 Mar 25. Review.


Prolonged PR interval, first-degree heart block and adverse cardiovascular outcomes: a systematic review and meta-analysis.

Kwok CS, Rashid M, Beynon R, Barker D, Patwala A, Morley-Davies A, Satchithananda D, Nolan J, Myint PK, Buchan I, Loke YK, Mamas MA.

Heart. 2016 May;102(9):672-80. doi: 10.1136/heartjnl-2015-308956. Epub 2016 Feb 15. Review.


PRISMA harms checklist: improving harms reporting in systematic reviews.

Zorzela L, Loke YK, Ioannidis JP, Golder S, Santaguida P, Altman DG, Moher D, Vohra S; PRISMAHarms Group.

BMJ. 2016 Feb 1;352:i157. doi: 10.1136/bmj.i157. Erratum in: BMJ. 2016;353:i2229.


The thorough QT study - do we need more of the same?

Loke YK.

Br J Clin Pharmacol. 2016 Mar;81(3):400-1. doi: 10.1111/bcp.12871. Epub 2016 Feb 17. No abstract available.


Value of intraoperative neurophysiological monitoring to reduce neurological complications in patients undergoing anterior cervical spine procedures for cervical spondylotic myelopathy.

Thirumala PD, Muralidharan A, Loke YK, Habeych M, Crammond D, Balzer J.

J Clin Neurosci. 2016 Mar;25:27-35. doi: 10.1016/j.jocn.2015.06.027. Epub 2015 Dec 8. Review.


Bone mineral density and fracture risk with long-term use of inhaled corticosteroids in patients with asthma: systematic review and meta-analysis.

Loke YK, Gilbert D, Thavarajah M, Blanco P, Wilson AM.

BMJ Open. 2015 Nov 24;5(11):e008554. doi: 10.1136/bmjopen-2015-008554. Review.


Erratum to: The association of health literacy with adherence in older adults, and its role in interventions: a systematic meta-review.

Geboers B, Brainard JS, Loke YK, Jansen CJ, Salter C, Reijneveld SA, de Winter AF.

BMC Public Health. 2015 Oct 26;15:1091. doi: 10.1186/s12889-015-2419-5. No abstract available.

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