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Items: 1 to 50 of 85

1.

How Accurate Is Inverse Electrocardiographic Mapping? A Systematic In Vivo Evaluation.

Bear LR, LeGrice IJ, Sands GB, Lever NA, Loiselle DS, Paterson DJ, Cheng LK, Smaill BH.

Circ Arrhythm Electrophysiol. 2018 May;11(5):e006108. doi: 10.1161/CIRCEP.117.006108.

PMID:
29700057
2.

Calcium mishandling impairs contraction in right ventricular hypertrophy prior to overt heart failure.

Power AS, Hickey AJ, Crossman DJ, Loiselle DS, Ward ML.

Pflugers Arch. 2018 Jul;470(7):1115-1126. doi: 10.1007/s00424-018-2125-0. Epub 2018 Mar 10.

PMID:
29525825
3.

Left-Ventricular Energetics in Pulmonary Arterial Hypertension-Induced Right-Ventricular Hypertrophic Failure.

Han JC, Guild SJ, Pham T, Nisbet L, Tran K, Taberner AJ, Loiselle DS.

Front Physiol. 2018 Jan 9;8:1115. doi: 10.3389/fphys.2017.01115. eCollection 2017.

4.

Real-time model-based control of afterload for in vitro cardiac tissue experimentation.

Garrett AS, Pham T, Loiselle DS, June-Chiew Han, Taberner AJ.

Conf Proc IEEE Eng Med Biol Soc. 2017 Jul;2017:1287-1290. doi: 10.1109/EMBC.2017.8037067.

PMID:
29060111
5.

The ineluctable constraints of thermodynamics in the aetiology of obesity.

Loiselle DS, Barclay CJ.

Clin Exp Pharmacol Physiol. 2018 Mar;45(3):219-225. doi: 10.1111/1440-1681.12869. Epub 2017 Nov 29. Review.

PMID:
28994136
6.

Experimental and modelling evidence of shortening heat in cardiac muscle.

Tran K, Han JC, Crampin EJ, Taberner AJ, Loiselle DS.

J Physiol. 2017 Oct 1;595(19):6313-6326. doi: 10.1113/JP274680. Epub 2017 Aug 22.

7.

Cardiac muscle energetics: Improved normalisation of heat using optical coherence tomography.

Cheuk ML, Johnston CM, June-Chiew Han, Loiselle DS, Nielsen PM, Taberner AJ.

Conf Proc IEEE Eng Med Biol Soc. 2016 Aug;2016:2905-2908. doi: 10.1109/EMBC.2016.7591337.

PMID:
28268921
8.

Thermodynamic analysis questions claims of improved cardiac efficiency by dietary fish oil.

Loiselle DS, Han JC, Goo E, Chapman B, Barclay CJ, Hickey AJ, Taberner AJ.

J Gen Physiol. 2016 Sep;148(3):183-93. doi: 10.1085/jgp.201611620.

9.

Myocardial energetics is not compromised during compensated hypertrophy in the Dahl salt-sensitive rat model of hypertension.

Tran K, Han JC, Taberner AJ, Barrett CJ, Crampin EJ, Loiselle DS.

Am J Physiol Heart Circ Physiol. 2016 Sep 1;311(3):H563-71. doi: 10.1152/ajpheart.00396.2016. Epub 2016 Jul 8.

10.

Four-Dimensional Imaging of Cardiac Trabeculae Contracting In Vitro Using Gated OCT.

Cheuk ML, Anderson AJ, Han JC, Lippok N, Vanholsbeeck F, Ruddy BP, Loiselle DS, Nielsen PM, Taberner AJ.

IEEE Trans Biomed Eng. 2017 Jan;64(1):218-224. doi: 10.1109/TBME.2016.2553154. Epub 2016 Apr 12.

PMID:
27093310
11.

Impaired ADP channeling to mitochondria and elevated reactive oxygen species in hypertensive hearts.

Power AS, Pham T, Loiselle DS, Crossman DH, Ward ML, Hickey AJ.

Am J Physiol Heart Circ Physiol. 2016 Jun 1;310(11):H1649-57. doi: 10.1152/ajpheart.00050.2016. Epub 2016 Apr 15.

12.

Cardiac activation heat remains inversely dependent on temperature over the range 27-37°C.

Johnston CM, Han JC, Loiselle DS, Nielsen PM, Taberner AJ.

Am J Physiol Heart Circ Physiol. 2016 Jun 1;310(11):H1512-9. doi: 10.1152/ajpheart.00903.2015. Epub 2016 Mar 25.

13.

Measuring the mechanical efficiency of a working cardiac muscle sample at body temperature using a flow-through calorimeter.

Taberner AJ, Johnston CM, Pham T, June-Chiew Han, Ruddy BP, Loiselle DS, Nielsen PM.

Conf Proc IEEE Eng Med Biol Soc. 2015 Aug;2015:7966-9. doi: 10.1109/EMBC.2015.7320240.

PMID:
26738140
14.

Muscle heat: a window into the thermodynamics of a molecular machine.

Loiselle DS, Johnston CM, Han JC, Nielsen PM, Taberner AJ.

Am J Physiol Heart Circ Physiol. 2016 Feb 1;310(3):H311-25. doi: 10.1152/ajpheart.00569.2015. Epub 2015 Nov 20. Review.

15.

Regulation of cardiac cellular bioenergetics: mechanisms and consequences.

Tran K, Loiselle DS, Crampin EJ.

Physiol Rep. 2015 Jul;3(7). pii: e12464. doi: 10.14814/phy2.12464.

16.

Does reduced myocardial efficiency in systemic hypertensive-hypertrophy correlate with increased left-ventricular wall thickness?

Han JC, Barrett CJ, Taberner AJ, Loiselle DS.

Hypertens Res. 2015 Aug;38(8):530-8. doi: 10.1038/hr.2015.37. Epub 2015 Mar 19.

PMID:
25787044
17.

Extracellular Ca2+-induced force restoration in K+-depressed skeletal muscle of the mouse involves an elevation of [K+]i: implications for fatigue.

Cairns SP, Leader JP, Loiselle DS, Higgins A, Lin W, Renaud JM.

J Appl Physiol (1985). 2015 Mar 15;118(6):662-74. doi: 10.1152/japplphysiol.00705.2013. Epub 2015 Jan 8.

18.

Reduced mechanical efficiency in left-ventricular trabeculae of the spontaneously hypertensive rat.

Han JC, Tran K, Johnston CM, Nielsen PM, Barrett CJ, Taberner AJ, Loiselle DS.

Physiol Rep. 2014 Nov 20;2(11). pii: e12211. doi: 10.14814/phy2.12211. Print 2014 Nov 1.

19.

Dietary supplementation with either saturated or unsaturated fatty acids does not affect the mechanoenergetics of the isolated rat heart.

Goo S, Han JC, Nisbet LA, Legrice IJ, Taberner AJ, Loiselle DS.

Physiol Rep. 2014 Mar 1;2(3):e00272. doi: 10.1002/phy2.272. Print 2014.

20.

Streptozotocin-induced diabetes prolongs twitch duration without affecting the energetics of isolated ventricular trabeculae.

Han JC, Tran K, Nielsen PM, Taberner AJ, Loiselle DS.

Cardiovasc Diabetol. 2014 Apr 15;13:79. doi: 10.1186/1475-2840-13-79.

21.

Dietary pre-exposure of rats to fish oil does not enhance myocardial efficiency of isolated working hearts or their left ventricular trabeculae.

Goo S, Han JC, Nisbet LA, LeGrice IJ, Taberner AJ, Loiselle DS.

J Physiol. 2014 Apr 15;592(8):1795-808. doi: 10.1113/jphysiol.2013.269977. Epub 2014 Feb 17.

22.

The afterload-dependent peak efficiency of the isolated working rat heart is unaffected by streptozotocin-induced diabetes.

Han JC, Goo S, Barrett CJ, Mellor KM, Taberner AJ, Loiselle DS.

Cardiovasc Diabetol. 2014 Jan 5;13:4. doi: 10.1186/1475-2840-13-4.

23.

Interventricular comparison of the energetics of contraction of trabeculae carneae isolated from the rat heart.

Han JC, Taberner AJ, Nielsen PM, Loiselle DS.

J Physiol. 2013 Feb 1;591(3):701-17. doi: 10.1113/jphysiol.2012.242719. Epub 2012 Nov 26.

24.

Comparison of the Gibbs and Suga formulations of cardiac energetics: the demise of "isoefficiency".

Han JC, Taberner AJ, Tran K, Goo S, Nickerson DP, Nash MP, Nielsen PM, Crampin EJ, Loiselle DS.

J Appl Physiol (1985). 2012 Oct;113(7):996-1003. doi: 10.1152/japplphysiol.00693.2011. Epub 2012 Aug 9. Review.

25.

Relating components of pressure-volume area in Suga's formulation of cardiac energetics to components of the stress-time integral.

Han JC, Taberner AJ, Tran K, Nickerson DP, Nash MP, Nielsen PM, Crampin EJ, Loiselle DS.

J Appl Physiol (1985). 2012 Oct;113(7):988-95. doi: 10.1152/japplphysiol.00438.2012. Epub 2012 Jul 26. Review.

26.

Myocardial twitch duration and the dependence of oxygen consumption on pressure-volume area: experiments and modelling.

Han JC, Tran K, Taberner AJ, Nickerson DP, Kirton RS, Nielsen PM, Ward ML, Nash MP, Crampin EJ, Loiselle DS.

J Physiol. 2012 Sep 15;590(18):4603-22. doi: 10.1113/jphysiol.2012.228965. Epub 2012 May 8.

27.

A work-loop calorimeter for measuring the force-length-heat relationship of working excised cardiac muscle fibers.

Taberner AJ, Han JC, Loiselle DS, Nielsen PM.

Conf Proc IEEE Eng Med Biol Soc. 2011;2011:1901-4. doi: 10.1109/IEMBS.2011.6090538.

PMID:
22254702
28.

An innovative work-loop calorimeter for in vitro measurement of the mechanics and energetics of working cardiac trabeculae.

Taberner AJ, Han JC, Loiselle DS, Nielsen PM.

J Appl Physiol (1985). 2011 Dec;111(6):1798-803. doi: 10.1152/japplphysiol.00752.2011. Epub 2011 Sep 8. Erratum in: J Appl Physiol. 2012 Mar;112(6):1090. Nielsen, Paul M F [corrected to Nielsen, Poul M F].

29.

Exacerbated potassium-induced paralysis of mouse soleus muscle at 37°C vis-à-vis 25°C: implications for fatigue. K+ -induced paralysis at 37°C.

Cairns SP, Leader JP, Loiselle DS.

Pflugers Arch. 2011 Apr;461(4):469-79. doi: 10.1007/s00424-011-0927-4. Epub 2011 Feb 22.

PMID:
21337119
30.

Radius-dependent decline of performance in isolated cardiac muscle does not reflect inadequacy of diffusive oxygen supply.

Han JC, Taberner AJ, Kirton RS, Nielsen PM, Archer R, Kim N, Loiselle DS.

Am J Physiol Heart Circ Physiol. 2011 Apr;300(4):H1222-36. doi: 10.1152/ajpheart.01157.2010. Epub 2011 Jan 7.

31.

Stress development, heat production and dynamic modulus of rat isolated cardiac trabeculae revealed in a flow-through micro-mechano-calorimeter.

Taberner AJ, Han JC, Kirton RS, Loiselle DS, Nielsen PM.

Conf Proc IEEE Eng Med Biol Soc. 2010;2010:1860-3. doi: 10.1109/IEMBS.2010.5626240.

PMID:
21095942
32.

Non-steady-state calcium handling in failing hearts from the spontaneously hypertensive rat.

Ward ML, Crossman DJ, Loiselle DS, Cannell MB.

Pflugers Arch. 2010 Nov;460(6):991-1001. doi: 10.1007/s00424-010-0876-3. Epub 2010 Sep 21.

PMID:
20857306
33.

Energetics of stress production in isolated cardiac trabeculae from the rat.

Han JC, Taberner AJ, Nielsen PM, Kirton RS, Ward ML, Loiselle DS.

Am J Physiol Heart Circ Physiol. 2010 Nov;299(5):H1382-94. doi: 10.1152/ajpheart.00454.2010. Epub 2010 Aug 20.

34.

A metabolite-sensitive, thermodynamically constrained model of cardiac cross-bridge cycling: implications for force development during ischemia.

Tran K, Smith NP, Loiselle DS, Crampin EJ.

Biophys J. 2010 Jan 20;98(2):267-76. doi: 10.1016/j.bpj.2009.10.011.

35.

Why has reversal of the actin-myosin cross-bridge cycle not been observed experimentally?

Loiselle DS, Tran K, Crampin EJ, Curtin NA.

J Appl Physiol (1985). 2010 Jun;108(6):1465-71. doi: 10.1152/japplphysiol.01198.2009. Epub 2010 Feb 4.

36.

A unique micromechanocalorimeter for simultaneous measurement of heat rate and force production of cardiac trabeculae carneae.

Han JC, Taberner AJ, Kirton RS, Nielsen PM, Smith NP, Loiselle DS.

J Appl Physiol (1985). 2009 Sep;107(3):946-51. doi: 10.1152/japplphysiol.00549.2009. Epub 2009 Jul 9.

37.

A thermodynamic model of the cardiac sarcoplasmic/endoplasmic Ca(2+) (SERCA) pump.

Tran K, Smith NP, Loiselle DS, Crampin EJ.

Biophys J. 2009 Mar 4;96(5):2029-42. doi: 10.1016/j.bpj.2008.11.045. Erratum in: Biophys J. 2011 Jun 8;100(11):2853.

38.

Changes of surface and t-tubular membrane excitability during fatigue with repeated tetani in isolated mouse fast- and slow-twitch muscle.

Cairns SP, Taberner AJ, Loiselle DS.

J Appl Physiol (1985). 2009 Jan;106(1):101-12. doi: 10.1152/japplphysiol.90878.2008. Epub 2008 Oct 23.

39.

Energetic consequences of mechanical loads.

Loiselle DS, Crampin EJ, Niederer SA, Smith NP, Barclay CJ.

Prog Biophys Mol Biol. 2008 Jun-Jul;97(2-3):348-66. doi: 10.1016/j.pbiomolbio.2008.02.015. Epub 2008 Feb 16. Review. Erratum in: Prog Biophys Mol Biol. 2009 Feb-Apr;99(2-3):114.

PMID:
18384845
40.

Double-sigmoid model for fitting fatigue profiles in mouse fast- and slow-twitch muscle.

Cairns SP, Robinson DM, Loiselle DS.

Exp Physiol. 2008 Jul;93(7):851-62. doi: 10.1113/expphysiol.2007.041285. Epub 2008 Mar 14.

41.

Can activation account for 80% of skeletal muscle energy use during isometric contraction?

Barclay CJ, Loiselle DS.

Am J Physiol Cell Physiol. 2007 Jan;292(1):C612; author reply C613-4. Epub 2006 Apr 5. No abstract available.

42.

Effects of BDM, [Ca2+]o, and temperature on the dynamic stiffness of quiescent cardiac trabeculae from rat.

Kirton RS, Taberner AJ, Nielsen PM, Young AA, Loiselle DS.

Am J Physiol Heart Circ Physiol. 2005 Apr;288(4):H1662-7. Epub 2004 Dec 2.

43.

The efficiency of muscle contraction.

Smith NP, Barclay CJ, Loiselle DS.

Prog Biophys Mol Biol. 2005 May;88(1):1-58. Review.

PMID:
15561300
44.

Strain softening behaviour in nonviable rat right-ventricular trabeculae, in the presence and the absence of butanedione monoxime.

Kirton RS, Taberner AJ, Nielsen PM, Young AA, Loiselle DS.

Exp Physiol. 2004 Sep;89(5):593-604. Epub 2004 Jul 15.

45.

Strain softening is not present during axial extensions of rat intact right ventricular trabeculae in the presence or absence of 2,3-butanedione monoxime.

Kirton RS, Taberner AJ, Young AA, Nielsen PM, Loiselle DS.

Am J Physiol Heart Circ Physiol. 2004 Feb;286(2):H708-15. Epub 2003 Oct 9.

46.

Species-independent metabolic response to an increase of [Ca(2+)](i) in quiescent cardiac muscle.

Ward ML, Cooper PJ, Hanley PJ, Loiselle DS.

Clin Exp Pharmacol Physiol. 2003 Aug;30(8):586-9.

PMID:
12890184
47.

Changes of action potentials and force at lowered [Na+]o in mouse skeletal muscle: implications for fatigue.

Cairns SP, Buller SJ, Loiselle DS, Renaud JM.

Am J Physiol Cell Physiol. 2003 Nov;285(5):C1131-41. Epub 2003 Jun 25.

48.

Restoration of osmotically inhibited twitch force in rat cardiac trabeculae: role of Na+-H+ exchange.

Cropper JR, Erac I, Loiselle DS.

Clin Exp Pharmacol Physiol. 2003 Mar;30(3):178-84.

PMID:
12603348
49.

Extracellular Ca2+ is obligatory for ouabain-induced potentiation of cardiac basal energy expenditure.

Guild SJ, Ward ML, Cooper PJ, Hanley PJ, Loiselle DS.

Clin Exp Pharmacol Physiol. 2003 Jan-Feb;30(1-2):103-9.

PMID:
12542462
50.

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