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Items: 1 to 50 of 64

1.

Will CRISPR Germline Engineering Close the Door to an Open Future?

Mintz RL, Loike JD, Fischbach RL.

Sci Eng Ethics. 2018 Oct 24. doi: 10.1007/s11948-018-0069-6. [Epub ahead of print]

PMID:
30357560
2.

Ethical rejections of xenotransplantation? The potential and challenges of using human-pig chimeras to create organs for transplantation.

Loike JD, Kadish A.

EMBO Rep. 2018 Aug;19(8). pii: e46337. doi: 10.15252/embr.201846337. Epub 2018 Jul 10. No abstract available.

PMID:
29991538
3.

Outer Limits of Biotechnologies: A Jewish Perspective.

Loike JD, Kadish A.

Rambam Maimonides Med J. 2018 Jan 29;9(1). doi: 10.5041/RMMJ.10328.

4.

Mitochondrial Replacement Therapy: Halachic Considerations for Enrolling in an Experimental Clinical Trial.

Tendler RM, Loike JD.

Rambam Maimonides Med J. 2015 Jul 30;6(3). doi: 10.5041/RMMJ.10216.

5.

Creating a three-parent child: an educational paradigm for the responsible conduct of research.

Fischbach RL, Benston S, Loike JD.

J Microbiol Biol Educ. 2014 Dec 15;15(2):186-90. doi: 10.1128/jmbe.v15i2.873. eCollection 2014 Dec.

6.

The HMGB1/RAGE axis triggers neutrophil-mediated injury amplification following necrosis.

Huebener P, Pradere JP, Hernandez C, Gwak GY, Caviglia JM, Mu X, Loike JD, Jenkins RE, Antoine DJ, Schwabe RF.

J Clin Invest. 2015 Feb;125(2):539-50. doi: 10.1172/JCI76887. Epub 2014 Dec 22.

7.

Neuronal MHC-I expression and its implications in synaptic function, axonal regeneration and Parkinson's and other brain diseases.

Cebrián C, Loike JD, Sulzer D.

Front Neuroanat. 2014 Oct 13;8:114. doi: 10.3389/fnana.2014.00114. eCollection 2014. Review.

8.

Neuroinflammation in Parkinson's disease animal models: a cell stress response or a step in neurodegeneration?

Cebrián C, Loike JD, Sulzer D.

Curr Top Behav Neurosci. 2015;22:237-70. doi: 10.1007/7854_2014_356. Review.

PMID:
25293443
9.

Cultural influences on transnational gestational surrogacy.

Zivotofsky AZ, Loike JD.

Am J Bioeth. 2014;14(5):44-6. doi: 10.1080/15265161.2014.892181. No abstract available.

PMID:
24766124
10.

Maternal-fetal cell transfer in surrogacy: ties that bind.

Fischbach RL, Loike JD.

Am J Bioeth. 2014;14(5):35-6. doi: 10.1080/15265161.2014.892179. No abstract available.

PMID:
24766119
11.

MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degeneration.

Cebrián C, Zucca FA, Mauri P, Steinbeck JA, Studer L, Scherzer CR, Kanter E, Budhu S, Mandelbaum J, Vonsattel JP, Zecca L, Loike JD, Sulzer D.

Nat Commun. 2014 Apr 16;5:3633. doi: 10.1038/ncomms4633.

12.

Lessons learned from undergraduate students in designing a science-based course in bioethics.

Loike JD, Rush BS, Schweber A, Fischbach RL.

CBE Life Sci Educ. 2013 Winter;12(4):701-10. doi: 10.1187/cbe.13-01-0012.

13.

Surface acoustic waves enhance neutrophil killing of bacteria.

Loike JD, Plitt A, Kothari K, Zumeris J, Budhu S, Kavalus K, Ray Y, Jacob H.

PLoS One. 2013 Aug 6;8(8):e68334. doi: 10.1371/journal.pone.0068334. Print 2013.

14.

BioCEP - a model educational program for cross-cultural bioethics.

Miller J, Loike JD.

Camb Q Healthc Ethics. 2012 Jul;21(3):409-16. doi: 10.1017/S0963180112000187. No abstract available.

PMID:
22624549
15.

Neurodegeneration and inflammation in Parkinson's disease.

Phani S, Loike JD, Przedborski S.

Parkinsonism Relat Disord. 2012 Jan;18 Suppl 1:S207-9. doi: 10.1016/S1353-8020(11)70064-5. Review.

PMID:
22166436
16.

CD8+ T cell concentration determines their efficiency in killing cognate antigen-expressing syngeneic mammalian cells in vitro and in mouse tissues.

Budhu S, Loike JD, Pandolfi A, Han S, Catalano G, Constantinescu A, Clynes R, Silverstein SC.

J Exp Med. 2010 Jan 18;207(1):223-35. doi: 10.1084/jem.20091279. Epub 2010 Jan 11.

17.

Jewish views on the beginnings of human life and the use of medical intervention to produce children.

Loike JD, Fischbach RL, Tendler MD.

Am J Bioeth. 2009 Nov;9(11):45-7. doi: 10.1080/15265160903263432. No abstract available.

PMID:
19882459
18.

Teachers' participation in research programs improves their students' achievement in science.

Silverstein SC, Dubner J, Miller J, Glied S, Loike JD.

Science. 2009 Oct 16;326(5951):440-2. doi: 10.1126/science.1177344.

19.

Reconstituting a human brain in animals: a Jewish perspective on human sanctity.

Loike JD, Tendler M.

Kennedy Inst Ethics J. 2008 Dec;18(4):347-67.

PMID:
19143409
20.

Postmortem fatherhood: life after life.

Fischbach RL, Loike JD.

Lancet. 2008 Jun 28;371(9631):2166-7. No abstract available.

PMID:
18595168
21.

Ma adam va-teda-ehu: halakhic criteria for defining human beings.

Loike JD, Tendler MD.

Tradition. 2003 Summer;37(2):1-19. No abstract available.

PMID:
15468502
22.

Determination of the critical concentration of neutrophils required to block bacterial growth in tissues.

Li Y, Karlin A, Loike JD, Silverstein SC.

J Exp Med. 2004 Sep 6;200(5):613-22.

23.

Statin inhibition of Fc receptor-mediated phagocytosis by macrophages is modulated by cell activation and cholesterol.

Loike JD, Shabtai DY, Neuhut R, Malitzky S, Lu E, Husemann J, Goldberg IJ, Silverstein SC.

Arterioscler Thromb Vasc Biol. 2004 Nov;24(11):2051-6. Epub 2004 Sep 2.

PMID:
15345508
24.

Revisiting the definition of homo sapiens.

Loike JD, Tendler MD.

Kennedy Inst Ethics J. 2002 Dec;12(4):343-50.

PMID:
12645611
25.

Adult mouse astrocytes degrade amyloid-beta in vitro and in situ.

Wyss-Coray T, Loike JD, Brionne TC, Lu E, Anankov R, Yan F, Silverstein SC, Husemann J.

Nat Med. 2003 Apr;9(4):453-7. Epub 2003 Mar 3.

PMID:
12612547
26.

Scavenger receptors in neurobiology and neuropathology: their role on microglia and other cells of the nervous system.

Husemann J, Loike JD, Anankov R, Febbraio M, Silverstein SC.

Glia. 2002 Nov;40(2):195-205. Review.

PMID:
12379907
27.

A critical concentration of neutrophils is required for effective bacterial killing in suspension.

Li Y, Karlin A, Loike JD, Silverstein SC.

Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):8289-94.

28.

Different G(i)-coupled chemoattractant receptors signal qualitatively different functions in human neutrophils.

Berger M, Budhu S, Lu E, Li Y, Loike D, Silverstein SC, Loike JD.

J Leukoc Biol. 2002 May;71(5):798-806.

PMID:
11994504
29.

The bacterial peptide N-formyl-Met-Leu-Phe inhibits killing of Staphylococcus epidermidis by human neutrophils in fibrin gels.

Li Y, Loike JD, Ember JA, Cleary PP, Lu E, Budhu S, Cao L, Silverstein SC.

J Immunol. 2002 Jan 15;168(2):816-24.

30.

Human cloning: scientific, ethical and Jewish perspectives.

Steinberg A, Loike JD.

Assia Jew Med Ethics. 1998 Sep;3(2):11-9. No abstract available.

PMID:
11657947
32.

Scavenger receptor class B type I (SR-BI) mediates adhesion of neonatal murine microglia to fibrillar beta-amyloid.

Husemann J, Loike JD, Kodama T, Silverstein SC.

J Neuroimmunol. 2001 Mar 1;114(1-2):142-50.

PMID:
11240025
33.

Mitochondrial DNA genotypes in nuclear transfer-derived cloned sheep.

Evans MJ, Gurer C, Loike JD, Wilmut I, Schnieke AE, Schon EA.

Nat Genet. 1999 Sep;23(1):90-3.

34.

Differential regulation of beta1 integrins by chemoattractants regulates neutrophil migration through fibrin.

Loike JD, Cao L, Budhu S, Marcantonio EE, El Khoury J, Hoffman S, Yednock TA, Silverstein SC.

J Cell Biol. 1999 Mar 8;144(5):1047-56.

35.
36.

Microglia, scavenger receptors, and the pathogenesis of Alzheimer's disease.

El Khoury J, Hickman SE, Thomas CA, Loike JD, Silverstein SC.

Neurobiol Aging. 1998 Jan-Feb;19(1 Suppl):S81-4. Review.

PMID:
9562474
37.

Lipoprotein lipase regulates Fc receptor-mediated phagocytosis by macrophages maintained in glucose-deficient medium.

Yin B, Loike JD, Kako Y, Weinstock PH, Breslow JL, Silverstein SC, Goldberg IJ.

J Clin Invest. 1997 Aug 1;100(3):649-57.

38.

Mac-1 (CD11b/CD18) is an oligodeoxynucleotide-binding protein.

Benimetskaya L, Loike JD, Khaled Z, Loike G, Silverstein SC, Cao L, el Khoury J, Cai TQ, Stein CA.

Nat Med. 1997 Apr;3(4):414-20.

PMID:
9095175
39.

Sodium-glucose cotransporters display sodium- and phlorizin-dependent water permeability.

Loike JD, Hickman S, Kuang K, Xu M, Cao L, Vera JC, Silverstein SC, Fischbarg J.

Am J Physiol. 1996 Nov;271(5 Pt 1):C1774-9.

PMID:
8944663
40.

Scavenger receptor-mediated adhesion of microglia to beta-amyloid fibrils.

El Khoury J, Hickman SE, Thomas CA, Cao L, Silverstein SC, Loike JD.

Nature. 1996 Aug 22;382(6593):716-9.

PMID:
8751442
41.

Fibrin regulates neutrophil migration in response to interleukin 8, leukotriene B4, tumor necrosis factor, and formyl-methionyl-leucyl-phenylalanine.

Loike JD, el Khoury J, Cao L, Richards CP, Rascoff H, Mandeville JT, Maxfield FR, Silverstein SC.

J Exp Med. 1995 May 1;181(5):1763-72.

42.

Macrophages adhere to glucose-modified basement membrane collagen IV via their scavenger receptors.

el Khoury J, Thomas CA, Loike JD, Hickman SE, Cao L, Silverstein SC.

J Biol Chem. 1994 Apr 8;269(14):10197-200.

43.

Functional characterization of antiadhesion molecules.

Hoffman S, Dutton SL, Ernst H, Boackle MK, Everman D, Tourkin A, Loike JD.

Perspect Dev Neurobiol. 1994;2(1):101-10. Review.

PMID:
7530136
44.

Role of facilitative glucose transporters in diffusional water permeability through J774 cells.

Loike JD, Cao L, Kuang K, Vera JC, Silverstein SC, Fischbarg J.

J Gen Physiol. 1993 Nov;102(5):897-906.

45.

Scientists must educate the public that NIH is the principal federal agency that supports biomedical research.

Silverstein SC, Loike JD.

FASEB J. 1993 Nov;7(14):1309. No abstract available.

PMID:
8224603
46.

Activated platelets form protected zones of adhesion on fibrinogen and fibronectin-coated surfaces.

Loike JD, Silverstein R, Cao L, Solomon L, Weitz J, Haber E, Matsueda GR, Bernatowicz MS, Silverstein SC.

J Cell Biol. 1993 May;121(4):945-55.

47.

Lactate transport in macrophages.

Loike JD, Kaback E, Silverstein SC, Steinberg TH.

J Immunol. 1993 Mar 1;150(5):1951-8.

PMID:
8436827
48.

The role of protected extracellular compartments in interactions between leukocytes, and platelets, and fibrin/fibrinogen matrices.

Loike JD, Silverstein R, Wright SD, Weitz JI, Huang AJ, Silverstein SC.

Ann N Y Acad Sci. 1992 Dec 4;667:163-72. Review.

PMID:
1309032
49.

Hypoxia induces glucose transporter expression in endothelial cells.

Loike JD, Cao L, Brett J, Ogawa S, Silverstein SC, Stern D.

Am J Physiol. 1992 Aug;263(2 Pt 1):C326-33.

PMID:
1514581
50.

CD11c/CD18 on neutrophils recognizes a domain at the N terminus of the A alpha chain of fibrinogen.

Loike JD, Sodeik B, Cao L, Leucona S, Weitz JI, Detmers PA, Wright SD, Silverstein SC.

Proc Natl Acad Sci U S A. 1991 Feb 1;88(3):1044-8.

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