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Items: 1 to 50 of 399

1.

Candida albicans white and opaque cells exhibit distinct spectra of organ colonization in mouse models of infection.

Takagi J, Singh-Babak SD, Lohse MB, Dalal CK, Johnson AD.

PLoS One. 2019 Jun 6;14(6):e0218037. doi: 10.1371/journal.pone.0218037. eCollection 2019.

2.

Context-dependent signalling of CXC chemokine receptor 4 (CXCR4) and atypical chemokine receptor 3 (ACKR3).

Heuninck J, Perpina Viciano C, Işbilir A, Caspar B, Capoferri D, Briddon SJ, Durroux T, Hill SJ, Lohse MJ, Milligan G, Pin JP, Hoffmann C.

Mol Pharmacol. 2019 May 15. pii: mol.118.115477. doi: 10.1124/mol.118.115477. [Epub ahead of print]

3.

Quantitative Single-Residue Bioorthogonal Labeling of G Protein-Coupled Receptors in Live Cells.

Serfling R, Seidel L, Bock A, Lohse MJ, Annibale P, Coin I.

ACS Chem Biol. 2019 May 23. doi: 10.1021/acschembio.8b01115. [Epub ahead of print]

PMID:
31074969
4.

Quantifying a Biocatalytic Product from a Few Living Microbial Cells Using Microfluidic Cultivation Coupled to FT-ICR-MS.

Dusny C, Lohse M, Reemtsma T, Schmid A, Lechtenfeld OJ.

Anal Chem. 2019 Jun 4;91(11):7012-7018. doi: 10.1021/acs.analchem.9b00978. Epub 2019 May 16.

PMID:
31055912
5.

Stepwise activation of a class C GPCR begins with millisecond dimer rearrangement.

Grushevskyi EO, Kukaj T, Schmauder R, Bock A, Zabel U, Schwabe T, Benndorf K, Lohse MJ.

Proc Natl Acad Sci U S A. 2019 May 14;116(20):10150-10155. doi: 10.1073/pnas.1900261116. Epub 2019 Apr 25.

6.

Publisher Correction: Internalized TSH receptors en route to the TGN induce local Gs-protein signaling and gene transcription.

Godbole A, Lyga S, Lohse MJ, Calebiro D.

Nat Commun. 2018 Dec 19;9(1):5459. doi: 10.1038/s41467-018-07821-7.

7.

A functional genetic variation of SLC6A2 repressor hsa-miR-579-3p upregulates sympathetic noradrenergic processes of fear and anxiety.

Hommers LG, Richter J, Yang Y, Raab A, Baumann C, Lang K, Schiele MA, Weber H, Wittmann A, Wolf C, Alpers GW, Arolt V, Domschke K, Fehm L, Fydrich T, Gerlach A, Gloster AT, Hamm AO, Helbig-Lang S, Kircher T, Lang T, Pané-Farré CA, Pauli P, Pfleiderer B, Reif A, Romanos M, Straube B, Ströhle A, Wittchen HU, Frantz S, Ertl G, Lohse MJ, Lueken U, Deckert J.

Transl Psychiatry. 2018 Oct 19;8(1):226. doi: 10.1038/s41398-018-0278-4.

8.

Bioluminescence resonance energy transfer-based biosensors allow monitoring of ligand- and transducer-mediated GPCR conformational changes.

Picard LP, Schönegge AM, Lohse MJ, Bouvier M.

Commun Biol. 2018 Aug 7;1:106. doi: 10.1038/s42003-018-0101-z. eCollection 2018.

9.

A universal bioluminescence resonance energy transfer sensor design enables high-sensitivity screening of GPCR activation dynamics.

Schihada H, Vandenabeele S, Zabel U, Frank M, Lohse MJ, Maiellaro I.

Commun Biol. 2018 Aug 7;1:105. doi: 10.1038/s42003-018-0072-0. eCollection 2018.

10.

Cyclopeptide COR-1 to treat beta1-adrenergic receptor antibody-induced heart failure.

Boivin-Jahns V, Uhland K, Holthoff HP, Beyersdorf N, Kocoski V, Kerkau T, Münch G, Lohse MJ, Ungerer M, Jahns R.

PLoS One. 2018 Aug 20;13(8):e0201160. doi: 10.1371/journal.pone.0201160. eCollection 2018.

11.

Inhibition of TOR Represses Nutrient Consumption, Which Improves Greening after Extended Periods of Etiolation.

Zhang Y, Zhang Y, McFarlane HE, Obata T, Richter AS, Lohse M, Grimm B, Persson S, Fernie AR, Giavalisco P.

Plant Physiol. 2018 Sep;178(1):101-117. doi: 10.1104/pp.18.00684. Epub 2018 Jul 26.

12.

In Vitro Culturing and Screening of Candida albicans Biofilms.

Gulati M, Lohse MB, Ennis CL, Gonzalez RE, Perry AM, Bapat P, Arevalo AV, Rodriguez DL, Nobile CJ.

Curr Protoc Microbiol. 2018 Aug;50(1):e60. doi: 10.1002/cpmc.60. Epub 2018 Jul 11.

13.

Development, organization and plasticity of auditory circuits: Lessons from a cherished colleague.

Lohse M, Bajo VM, King AJ.

Eur J Neurosci. 2019 Apr;49(8):990-1004. doi: 10.1111/ejn.13979. Epub 2018 Aug 16. Review.

14.

Molecular details of dimerization kinetics reveal negligible populations of transient µ-opioid receptor homodimers at physiological concentrations.

Meral D, Provasi D, Prada-Gracia D, Möller J, Marino K, Lohse MJ, Filizola M.

Sci Rep. 2018 May 16;8(1):7705. doi: 10.1038/s41598-018-26070-8.

15.

Nε-Acryloyllysine Piperazides as Irreversible Inhibitors of Transglutaminase 2: Synthesis, Structure-Activity Relationships, and Pharmacokinetic Profiling.

Wodtke R, Hauser C, Ruiz-Gómez G, Jäckel E, Bauer D, Lohse M, Wong A, Pufe J, Ludwig FA, Fischer S, Hauser S, Greif D, Pisabarro MT, Pietzsch J, Pietsch M, Löser R.

J Med Chem. 2018 May 24;61(10):4528-4560. doi: 10.1021/acs.jmedchem.8b00286. Epub 2018 May 10.

PMID:
29664627
16.

All-optical microscope autofocus based on an electrically tunable lens and a totally internally reflected IR laser.

Bathe-Peters M, Annibale P, Lohse MJ.

Opt Express. 2018 Feb 5;26(3):2359-2368. doi: 10.1364/OE.26.002359.

17.

Structure-Activity Relationships and Computational Investigations into the Development of Potent and Balanced Dual-Acting Butyrylcholinesterase Inhibitors and Human Cannabinoid Receptor 2 Ligands with Pro-Cognitive in Vivo Profiles.

Dolles D, Hoffmann M, Gunesch S, Marinelli O, Möller J, Santoni G, Chatonnet A, Lohse MJ, Wittmann HJ, Strasser A, Nabissi M, Maurice T, Decker M.

J Med Chem. 2018 Feb 22;61(4):1646-1663. doi: 10.1021/acs.jmedchem.7b01760. Epub 2018 Feb 5.

PMID:
29400965
18.

Exploring 4D quantum Hall physics with a 2D topological charge pump.

Lohse M, Schweizer C, Price HM, Zilberberg O, Bloch I.

Nature. 2018 Jan 3;553(7686):55-58. doi: 10.1038/nature25000.

PMID:
29300006
19.

Evolutionary action and structural basis of the allosteric switch controlling β2AR functional selectivity.

Schönegge AM, Gallion J, Picard LP, Wilkins AD, Le Gouill C, Audet M, Stallaert W, Lohse MJ, Kimmel M, Lichtarge O, Bouvier M.

Nat Commun. 2017 Dec 18;8(1):2169. doi: 10.1038/s41467-017-02257-x.

20.

Emotional priming depends on the degree of conscious experience.

Lohse M, Overgaard M.

Neuropsychologia. 2019 May;128:96-102. doi: 10.1016/j.neuropsychologia.2017.10.028. Epub 2017 Nov 10.

21.

Related GPCRs couple differently to Gs: preassociation between G protein and 5-HT7 serotonin receptor reveals movement of Gαs upon receptor activation.

Andressen KW, Ulsund AH, Krobert KA, Lohse MJ, Bünemann M, Levy FO.

FASEB J. 2018 Feb;32(2):1059-1069. doi: 10.1096/fj.201700486R. Epub 2018 Jan 3.

PMID:
29079700
22.

Development and regulation of single- and multi-species Candida albicans biofilms.

Lohse MB, Gulati M, Johnson AD, Nobile CJ.

Nat Rev Microbiol. 2018 Jan;16(1):19-31. doi: 10.1038/nrmicro.2017.107. Epub 2017 Oct 3. Review.

23.

Single-molecule imaging reveals receptor-G protein interactions at cell surface hot spots.

Sungkaworn T, Jobin ML, Burnecki K, Weron A, Lohse MJ, Calebiro D.

Nature. 2017 Oct 26;550(7677):543-547. doi: 10.1038/nature24264. Epub 2017 Oct 18.

PMID:
29045395
24.

Thalamic input to auditory cortex is locally heterogeneous but globally tonotopic.

Vasquez-Lopez SA, Weissenberger Y, Lohse M, Keating P, King AJ, Dahmen JC.

Elife. 2017 Sep 11;6. pii: e25141. doi: 10.7554/eLife.25141.

25.

Internalized TSH receptors en route to the TGN induce local Gs-protein signaling and gene transcription.

Godbole A, Lyga S, Lohse MJ, Calebiro D.

Nat Commun. 2017 Sep 5;8(1):443. doi: 10.1038/s41467-017-00357-2. Erratum in: Nat Commun. 2018 Dec 19;9(1):5459.

26.

Increased fear learning, spatial learning as well as neophobia in Rgs2-/- mice.

Raab A, Popp S, Lesch KP, Lohse MJ, Fischer M, Deckert J, Hommers L.

Genes Brain Behav. 2018 Apr;17(4):e12420. doi: 10.1111/gbb.12420. Epub 2017 Sep 22.

PMID:
28846187
27.

Low-frequency oscillations employ a general coding of the spatio-temporal similarity of dynamic faces.

Furl N, Lohse M, Pizzorni-Ferrarese F.

Neuroimage. 2017 Aug 15;157:486-499. doi: 10.1016/j.neuroimage.2017.06.023. Epub 2017 Jun 12.

28.

Ligand-Specific Restriction of Extracellular Conformational Dynamics Constrains Signaling of the M2 Muscarinic Receptor.

Bermudez M, Bock A, Krebs F, Holzgrabe U, Mohr K, Lohse MJ, Wolber G.

ACS Chem Biol. 2017 Jul 21;12(7):1743-1748. doi: 10.1021/acschembio.7b00275. Epub 2017 Jun 12.

PMID:
28585805
29.

Sensitivity of White and Opaque Candida albicans Cells to Antifungal Drugs.

Craik VB, Johnson AD, Lohse MB.

Antimicrob Agents Chemother. 2017 Jul 25;61(8). pii: e00166-17. doi: 10.1128/AAC.00166-17. Print 2017 Aug.

30.

Experimental and mathematical analysis of cAMP nanodomains.

Lohse C, Bock A, Maiellaro I, Hannawacker A, Schad LR, Lohse MJ, Bauer WR.

PLoS One. 2017 Apr 13;12(4):e0174856. doi: 10.1371/journal.pone.0174856. eCollection 2017.

31.

Assessment and Optimizations of Candida albicans In Vitro Biofilm Assays.

Lohse MB, Gulati M, Valle Arevalo A, Fishburn A, Johnson AD, Nobile CJ.

Antimicrob Agents Chemother. 2017 Apr 24;61(5). pii: e02749-16. doi: 10.1128/AAC.02749-16. Print 2017 May.

32.

Phenotypic Profiling Reveals that Candida albicans Opaque Cells Represent a Metabolically Specialized Cell State Compared to Default White Cells.

Ene IV, Lohse MB, Vladu AV, Morschhäuser J, Johnson AD, Bennett RJ.

MBio. 2016 Nov 22;7(6). pii: e01269-16. doi: 10.1128/mBio.01269-16.

33.

Spin Pumping and Measurement of Spin Currents in Optical Superlattices.

Schweizer C, Lohse M, Citro R, Bloch I.

Phys Rev Lett. 2016 Oct 21;117(17):170405. Epub 2016 Oct 21.

PMID:
27824444
34.

cAMP Signals in Drosophila Motor Neurons Are Confined to Single Synaptic Boutons.

Maiellaro I, Lohse MJ, Kittel RJ, Calebiro D.

Cell Rep. 2016 Oct 25;17(5):1238-1246. doi: 10.1016/j.celrep.2016.09.090.

35.

Global Identification of Biofilm-Specific Proteolysis in Candida albicans.

Winter MB, Salcedo EC, Lohse MB, Hartooni N, Gulati M, Sanchez H, Takagi J, Hube B, Andes DR, Johnson AD, Craik CS, Nobile CJ.

MBio. 2016 Sep 13;7(5). pii: e01514-16. doi: 10.1128/mBio.01514-16.

36.

The Interplay between Carbon Availability and Growth in Different Zones of the Growing Maize Leaf.

Czedik-Eysenberg A, Arrivault S, Lohse MA, Feil R, Krohn N, Encke B, Nunes-Nesi A, Fernie AR, Lunn JE, Sulpice R, Stitt M.

Plant Physiol. 2016 Oct;172(2):943-967. Epub 2016 Aug 31.

37.

Ligand Binding Ensembles Determine Graded Agonist Efficacies at a G Protein-coupled Receptor.

Bock A, Bermudez M, Krebs F, Matera C, Chirinda B, Sydow D, Dallanoce C, Holzgrabe U, De Amici M, Lohse MJ, Wolber G, Mohr K.

J Biol Chem. 2016 Jul 29;291(31):16375-89. doi: 10.1074/jbc.M116.735431. Epub 2016 Jun 13.

38.

Systematic Genetic Screen for Transcriptional Regulators of the Candida albicans White-Opaque Switch.

Lohse MB, Ene IV, Craik VB, Hernday AD, Mancera E, Morschhäuser J, Bennett RJ, Johnson AD.

Genetics. 2016 Aug;203(4):1679-92. doi: 10.1534/genetics.116.190645. Epub 2016 Jun 8.

39.

Effective Connectivity from Early Visual Cortex to Posterior Occipitotemporal Face Areas Supports Face Selectivity and Predicts Developmental Prosopagnosia.

Lohse M, Garrido L, Driver J, Dolan RJ, Duchaine BC, Furl N.

J Neurosci. 2016 Mar 30;36(13):3821-8. doi: 10.1523/JNEUROSCI.3621-15.2016.

40.

β-Arrestin biosensors reveal a rapid, receptor-dependent activation/deactivation cycle.

Nuber S, Zabel U, Lorenz K, Nuber A, Milligan G, Tobin AB, Lohse MJ, Hoffmann C.

Nature. 2016 Mar 31;531(7596):661-4. doi: 10.1038/nature17198. Epub 2016 Mar 23.

41.

Erratum: Cardiac RKIP induces a beneficial β-adrenoceptor-dependent positive inotropy.

Schmid E, Neef S, Berlin C, Tomasovic A, Kahlert K, Nordbeck P, Deiss K, Denzinger S, Herrmann S, Wettwer E, Weidendorfer M, Becker D, Schäfer F, Wagner N, Ergün S, Schmitt JP, Katus HA, Weidemann F, Ravens U, Maack C, Hein L, Ertl G, Müller OJ, Maier LS, Lohse MJ, Lorenz K.

Nat Med. 2016 Feb;22(2):217. doi: 10.1038/nm0216-217c. No abstract available.

PMID:
26845407
42.

Persistent cAMP Signaling by Internalized LH Receptors in Ovarian Follicles.

Lyga S, Volpe S, Werthmann RC, Götz K, Sungkaworn T, Lohse MJ, Calebiro D.

Endocrinology. 2016 Apr;157(4):1613-21. doi: 10.1210/en.2015-1945. Epub 2016 Feb 1.

PMID:
26828746
43.

Ssn6 Defines a New Level of Regulation of White-Opaque Switching in Candida albicans and Is Required For the Stochasticity of the Switch.

Hernday AD, Lohse MB, Nobile CJ, Noiman L, Laksana CN, Johnson AD.

MBio. 2016 Jan 26;7(1):e01565-15. doi: 10.1128/mBio.01565-15.

44.

Identification and Characterization of Wor4, a New Transcriptional Regulator of White-Opaque Switching.

Lohse MB, Johnson AD.

G3 (Bethesda). 2016 Jan 15;6(3):721-9. doi: 10.1534/g3.115.024885.

45.

Genome-Wide Chromatin Immunoprecipitation in Candida albicans and Other Yeasts.

Lohse MB, Kongsomboonvech P, Madrigal M, Hernday AD, Nobile CJ.

Methods Mol Biol. 2016;1361:161-84. doi: 10.1007/978-1-4939-3079-1_10.

46.

Cardiac RKIP induces a beneficial β-adrenoceptor-dependent positive inotropy.

Schmid E, Neef S, Berlin C, Tomasovic A, Kahlert K, Nordbeck P, Deiss K, Denzinger S, Herrmann S, Wettwer E, Weidendorfer M, Becker D, Schäfer F, Wagner N, Ergün S, Schmitt JP, Katus HA, Weidemann F, Ravens U, Maack C, Hein L, Ertl G, Müller OJ, Maier LS, Lohse MJ, Lorenz K.

Nat Med. 2015 Nov;21(11):1298-306. doi: 10.1038/nm.3972. Epub 2015 Oct 19. Erratum in: Nat Med. 2016 Feb;22(2):217.

PMID:
26479924
47.

Impact of Small Monetary Incentives on Exercise in University Students.

Strohacker K, Galárraga O, Emerson J, Fricchione SR, Lohse M, Williams DM.

Am J Health Behav. 2015 Nov;39(6):779-86. doi: 10.5993/AJHB.39.6.5.

PMID:
26450545
48.

Single-Molecule Fluorescence Microscopy for the Analysis of Fast Receptor Dynamics.

Wagner J, Sungkaworn T, Heinze KG, Lohse MJ, Calebiro D.

Methods Mol Biol. 2015;1335:53-66. doi: 10.1007/978-1-4939-2914-6_5.

PMID:
26260594
49.

The ins and outs of adrenergic signaling.

Lohse MJ.

J Mol Med (Berl). 2015 Sep;93(9):955-62. doi: 10.1007/s00109-015-1323-x. Epub 2015 Jul 23. Review.

PMID:
26199112
50.

Spatial and Temporal Aspects of Signaling by G-Protein-Coupled Receptors.

Lohse MJ, Hofmann KP.

Mol Pharmacol. 2015 Sep;88(3):572-8. doi: 10.1124/mol.115.100248. Epub 2015 Jul 16. Review.

PMID:
26184590

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