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Items: 40

1.

Acute and Repeated Treatment with 5-PAHSA or 9-PAHSA Isomers Does Not Improve Glucose Control in Mice.

Pflimlin E, Bielohuby M, Korn M, Breitschopf K, Löhn M, Wohlfart P, Konkar A, Podeschwa M, Bärenz F, Pfenninger A, Schwahn U, Opatz T, Reimann M, Petry S, Tennagels N.

Cell Metab. 2018 Aug 7;28(2):217-227.e13. doi: 10.1016/j.cmet.2018.05.028. Epub 2018 Jun 21.

PMID:
29937376
2.

Synthesis and Characterization of a Promising Novel FFAR1/GPR40 Targeting Fluorescent Probe for β-Cell Imaging.

Bertrand R, Wolf A, Ivashchenko Y, Löhn M, Schäfer M, Brönstrup M, Gotthardt M, Derdau V, Plettenburg O.

ACS Chem Biol. 2016 Jun 17;11(6):1745-54. doi: 10.1021/acschembio.5b00791. Epub 2016 Apr 26.

PMID:
27115176
3.

Discovery and pharmacological characterization of a novel potent inhibitor of diacylglycerol-sensitive TRPC cation channels.

Maier T, Follmann M, Hessler G, Kleemann HW, Hachtel S, Fuchs B, Weissmann N, Linz W, Schmidt T, Löhn M, Schroeter K, Wang L, Rütten H, Strübing C.

Br J Pharmacol. 2015 Jul;172(14):3650-60. doi: 10.1111/bph.13151. Epub 2015 May 19.

4.

Microfabricated microporous membranes reduce the host immune response and prolong the functional lifetime of a closed-loop insulin delivery implant in a type 1 diabetic rat model.

Li J, Chu MK, Gordijo CR, Abbasi AZ, Chen K, Adissu HA, Löhn M, Giacca A, Plettenburg O, Wu XY.

Biomaterials. 2015 Apr;47:51-61. doi: 10.1016/j.biomaterials.2015.01.005. Epub 2015 Feb 4.

PMID:
25682160
5.

End-organ protection in hypertension by the novel and selective Rho-kinase inhibitor, SAR407899.

Löhn M, Plettenburg O, Kannt A, Kohlmann M, Hofmeister A, Kadereit D, Monecke P, Schiffer A, Schulte A, Ruetten H, Ivashchenko Y.

World J Cardiol. 2015 Jan 26;7(1):31-42. doi: 10.4330/wjc.v7.i1.31.

6.

Rho kinase inhibition mitigates sunitinib-induced rise in arterial pressure and renal vascular resistance but not increased renal sodium reabsorption.

Grisk O, Koenen A, Meissner T, Donner A, Braun D, Steinbach A, Glöckl G, Zimmermann U, Evert K, Evert M, Katsari E, Löhn M, Plettenburg O, Rettig R.

J Hypertens. 2014 Nov;32(11):2199-210; discussion 2110. doi: 10.1097/HJH.0000000000000326.

PMID:
25275248
7.

Activation of Rac-1 and RhoA contributes to podocyte injury in chronic kidney disease.

Babelova A, Jansen F, Sander K, Löhn M, Schäfer L, Fork C, Ruetten H, Plettenburg O, Stark H, Daniel C, Amann K, Pavenstädt H, Jung O, Brandes RP.

PLoS One. 2013 Nov 7;8(11):e80328. doi: 10.1371/journal.pone.0080328. eCollection 2013.

8.

Inhibition of diacylglycerol-sensitive TRPC channels by synthetic and natural steroids.

Miehe S, Crause P, Schmidt T, Löhn M, Kleemann HW, Licher T, Dittrich W, Rütten H, Strübing C.

PLoS One. 2012;7(4):e35393. doi: 10.1371/journal.pone.0035393. Epub 2012 Apr 17.

9.

The Rho kinase inhibitor SAR407899 potently inhibits endothelin-1-induced constriction of renal resistance arteries.

Grisk O, Schlüter T, Reimer N, Zimmermann U, Katsari E, Plettenburg O, Löhn M, Wollert HG, Rettig R.

J Hypertens. 2012 May;30(5):980-9. doi: 10.1097/HJH.0b013e328351d459.

PMID:
22388233
10.

Pharmacological characterization of SAR407899, a novel rho-kinase inhibitor.

Löhn M, Plettenburg O, Ivashchenko Y, Kannt A, Hofmeister A, Kadereit D, Schaefer M, Linz W, Kohlmann M, Herbert JM, Janiak P, O'Connor SE, Ruetten H.

Hypertension. 2009 Sep;54(3):676-83. doi: 10.1161/HYPERTENSIONAHA.109.134353. Epub 2009 Jul 13.

PMID:
19597037
11.

Biochemistry and pharmacology of novel anthranilic acid derivatives activating heme-oxidized soluble guanylyl cyclase.

Schindler U, Strobel H, Schönafinger K, Linz W, Löhn M, Martorana PA, Rütten H, Schindler PW, Busch AE, Sohn M, Töpfer A, Pistorius A, Jannek C, Mülsch A.

Mol Pharmacol. 2006 Apr;69(4):1260-8. Epub 2005 Dec 6.

12.

Insulin-sensitizing and cardiovascular effects of the sodium-hydrogen exchange inhibitor, cariporide, in the JCR: LA-cp rat and db/db mouse.

Russell JC, Proctor SD, Kelly SE, Löhn M, Busch AE, Schäfer S.

J Cardiovasc Pharmacol. 2005 Dec;46(6):746-53.

PMID:
16306797
13.

Long term Rho-kinase inhibition ameliorates endothelial dysfunction in LDL-Receptor deficient mice.

Steioff K, Rütten H, Busch AE, Plettenburg O, Ivashchenko Y, Löhn M.

Eur J Pharmacol. 2005 Apr 11;512(2-3):247-9.

PMID:
15840411
14.

Down-regulation of calpain 9 is linked to hypertensive heart and kidney disease.

Markmann A, Schäfer S, Linz W, Löhn M, Busch AE, Wohlfart P.

Cell Physiol Biochem. 2005;15(1-4):109-16.

15.

Inhibition of Rho-kinase stimulates nitric oxide-independent vasorelaxation.

Löhn M, Steioff K, Bleich M, Busch AE, Ivashchenko Y.

Eur J Pharmacol. 2005 Jan 10;507(1-3):179-86. Epub 2004 Dec 31.

PMID:
15659308
16.

Chronic vasopeptidase inhibition normalizes diabetic endothelial dysfunction.

Schäfer S, Steioff K, Linz W, Bleich M, Busch AE, Löhn M.

Eur J Pharmacol. 2004 Jan 26;484(2-3):361-2.

PMID:
14744624
17.

Regulation of arterial tone by smooth muscle myosin type II.

Löhn M, Kämpf D, Gui-Xuan C, Haller H, Luft FC, Gollasch M.

Am J Physiol Cell Physiol. 2002 Nov;283(5):C1383-9.

18.

Periadventitial fat releases a vascular relaxing factor.

Löhn M, Dubrovska G, Lauterbach B, Luft FC, Gollasch M, Sharma AM.

FASEB J. 2002 Jul;16(9):1057-63.

PMID:
12087067
19.

Cilnidipine is a novel slow-acting blocker of vascular L-type calcium channels that does not target protein kinase C.

Löhn M, Muzzulini U, Essin K, Tsang SY, Kirsch T, Litteral J, Waldron P, Conrad H, Klugbauer N, Hofmann F, Haller H, Luft FC, Huang Y, Gollasch M.

J Hypertens. 2002 May;20(5):885-93.

PMID:
12011649
20.

Cell cycle retardation in monocytoid cells induced by aminopeptidase N (CD13).

Löhn M, Mueller C, Langner J.

Leuk Lymphoma. 2002 Feb;43(2):407-13.

PMID:
11999577
21.

Regulation of calcium sparks and spontaneous transient outward currents by RyR3 in arterial vascular smooth muscle cells.

Löhn M, Jessner W, Fürstenau M, Wellner M, Sorrentino V, Haller H, Luft FC, Gollasch M.

Circ Res. 2001 Nov 23;89(11):1051-7.

PMID:
11717163
22.

beta(1)-Subunit of BK channels regulates arterial wall[Ca(2+)] and diameter in mouse cerebral arteries.

Löhn M, Lauterbach B, Haller H, Pongs O, Luft FC, Gollasch M.

J Appl Physiol (1985). 2001 Sep;91(3):1350-4.

23.

Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted mice.

Drab M, Verkade P, Elger M, Kasper M, Lohn M, Lauterbach B, Menne J, Lindschau C, Mende F, Luft FC, Schedl A, Haller H, Kurzchalia TV.

Science. 2001 Sep 28;293(5539):2449-52. Epub 2001 Aug 9.

24.

Sodium block and depolarization diminish P2Z-dependent Ca2+ entry in human B lymphocytes.

Löhn M, Klapperstück M, Riemann D, Markwardt F.

Cell Calcium. 2001 Jun;29(6):395-408.

PMID:
11352505
25.

Mice with disrupted BK channel beta1 subunit gene feature abnormal Ca(2+) spark/STOC coupling and elevated blood pressure.

Plüger S, Faulhaber J, Fürstenau M, Löhn M, Waldschütz R, Gollasch M, Haller H, Luft FC, Ehmke H, Pongs O.

Circ Res. 2000 Nov 24;87(11):E53-60.

PMID:
11090555
26.

Ignition of calcium sparks in arterial and cardiac muscle through caveolae.

Löhn M, Fürstenau M, Sagach V, Elger M, Schulze W, Luft FC, Haller H, Gollasch M.

Circ Res. 2000 Nov 24;87(11):1034-9.

PMID:
11090549
27.

Calcium sparks in human coronary artery smooth muscle cells resolved by confocal imaging.

Fürstenau M, Löhn M, Ried C, Luft FC, Haller H, Gollasch M.

J Hypertens. 2000 Sep;18(9):1215-22.

PMID:
10994752
28.

Ca2+ channels, 'quantized' Ca2+ release, and differentiation of myocytes in the cardiovascular system.

Gollasch M, Löhn M, Furstenau M, Nelson MT, Luft FC, Haller H.

J Hypertens. 2000 Aug;18(8):989-98. Review.

PMID:
10953988
29.

Ca2+ channels, Ca2+ sparks, and regulation of arterial smooth muscle function.

Gollasch M, Löhn M, Fürstenau M, Nelson MT, Luft FC, Haller H.

Z Kardiol. 2000;89 Suppl 2:15-9. Review.

PMID:
10769399
30.

Purinoceptors in human B-lymphocytes.

Markwardt F, Klapperstück M, Löhn M, Riemann D, Büttner C, Schmalzing G.

Prog Brain Res. 1999;120:345-53. No abstract available.

PMID:
10551010
31.

[Liposomal DNA transfection of human sarcoma cells with p53 alterations].

Meye A, Würl P, Löhn M, Lasch J, Bache M, Hinze R, Holzhausen HJ, Schmidt H, Rath FW, Taubert H.

Verh Dtsch Ges Pathol. 1998;82:220-5. German.

PMID:
10095438
32.

Monocyte infiltration and adhesion molecules in a rat model of high human renin hypertension.

Mervaala EM, Müller DN, Park JK, Schmidt F, Löhn M, Breu V, Dragun D, Ganten D, Haller H, Luft FC.

Hypertension. 1999 Jan;33(1 Pt 2):389-95.

PMID:
9931135
33.
34.

Aminopeptidase N-mediated signal transduction and inhibition of proliferation of human myeloid cells.

Löhn M, Mueller C, Thiele K, Kähne T, Riemann D, Langner J.

Adv Exp Med Biol. 1997;421:85-91. No abstract available.

PMID:
9330684
35.

Two transfected endothelial cell lines expressing high levels of membrane bound or soluble aminopeptidase N.

Thiele K, Riemann D, Kehlen A, Löhn M, Vogel LK, Langner J.

Adv Exp Med Biol. 1997;421:81-4. No abstract available.

PMID:
9330683
36.

Co-incubation of lymphocytes with fibroblast-like synoviocytes and other cell types can induce lymphocytic surface expression of aminopeptidase N/CD13.

Riemann D, Kehlen A, Thiele K, Löhn M, Langner J.

Adv Exp Med Biol. 1997;421:75-9. No abstract available.

PMID:
9330682
37.

Purinoceptor-operated cationic channels in human B lymphocytes.

Markwardt F, Löhn M, Böhm T, Klapperstück M.

J Physiol. 1997 Jan 1;498 ( Pt 1):143-51.

38.

Deformation of the Bowditch staircase in Ca(2+)-overloaded mammalian cardiac tissue--a calcium phenomenon?

Löhn M, Szymanski G, Markwardt F.

Mol Cell Biochem. 1996 Jul-Aug;160-161:13-25.

PMID:
8901450
39.

Nonselective cationic currents elicited by extracellular ATP in human B-lymphocytes.

Bretschneider F, Klapperstück M, Löhn M, Markwardt F.

Pflugers Arch. 1995 Mar;429(5):691-8.

PMID:
7540747
40.

Effects of cooling the legs on performance in a standard Wingate anaerobic power test.

Crowley GC, Garg A, Lohn MS, Van Someren N, Wade AJ.

Br J Sports Med. 1991 Dec;25(4):200-3.

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