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Items: 1 to 50 of 66

1.

Acute Lymphoblastic Leukemia With INPP5D-ABL1 Fusion Responds to Imatinib Treatment.

Poukka M, Lund-Aho T, Raittinen P, Nikkilä A, Kivinen K, Lundán T, Porkka K, Lohi O.

J Pediatr Hematol Oncol. 2018 Jul 24. doi: 10.1097/MPH.0000000000001267. [Epub ahead of print]

PMID:
30045148
2.

Radiation exposure from computerised tomography and risk of childhood leukemia: Finnish register-based case-control study of childhood leukemia (FRECCLE).

Nikkilä A, Raitanen J, Lohi O, Auvinen A.

Haematologica. 2018 Jul 5. pii: haematol.2018.187716. doi: 10.3324/haematol.2018.187716. [Epub ahead of print]

3.

Effects of incomplete residential histories on studies of environmental exposure with application to childhood leukaemia and background radiation.

Nikkilä A, Kendall G, Raitanen J, Spycher B, Lohi O, Auvinen A.

Environ Res. 2018 Jun 22;166:466-472. doi: 10.1016/j.envres.2018.06.035. [Epub ahead of print]

PMID:
29945121
4.

Erratum: Whole-exome sequencing identifies germline mutation in TP53 and ATRX in a child with genomically aberrant AT/RT and her mother with anaplastic astrocytoma.

Nordfors K, Haapasalo J, Afyounian E, Tuominen J, Annala M, Häyrynen S, Karhu R, Helén P, Lohi O, Nykter M, Haapasalo H, Granberg KJ.

Cold Spring Harb Mol Case Stud. 2018 Jun 1;4(3). pii: a003129. doi: 10.1101/mcs.a003129. Print 2018 Jun. No abstract available.

5.

Whole-exome sequencing identifies germline mutation in TP53 and ATRX in a child with genomically aberrant AT/RT and her mother with anaplastic astrocytoma.

Nordfors K, Haapasalo J, Afyounian E, Tuominen J, Annala M, Häyrynen S, Karhu R, Helén P, Lohi O, Nykter M, Haapasalo H, Granberg KJ.

Cold Spring Harb Mol Case Stud. 2018 Apr 2;4(2). pii: a002246. doi: 10.1101/mcs.a002246. Print 2018 Apr. Erratum in: Cold Spring Harb Mol Case Stud. 2018 Jun 1;4(3):.

6.

HOXA9 Cooperates with Activated JAK/STAT Signaling to Drive Leukemia Development.

de Bock CE, Demeyer S, Degryse S, Verbeke D, Sweron B, Gielen O, Vandepoel R, Vicente C, Vanden Bempt M, Dagklis A, Geerdens E, Bornschein S, Gijsbers R, Soulier J, Meijerink JP, Heinäniemi M, Teppo S, Bouvy-Liivrand M, Lohi O, Radaelli E, Cools J.

Cancer Discov. 2018 May;8(5):616-631. doi: 10.1158/2159-8290.CD-17-0583. Epub 2018 Mar 1.

PMID:
29496663
7.

Novel variants in Nordic patients referred for genetic testing of telomere-related disorders.

Norberg A, Rosén A, Raaschou-Jensen K, Kjeldsen L, Moilanen JS, Paulsson-Karlsson Y, Baliakas P, Lohi O, Ahmed A, Kittang AO, Larsson P, Roos G, Degerman S, Hultdin M.

Eur J Hum Genet. 2018 Jun;26(6):858-867. doi: 10.1038/s41431-018-0112-8. Epub 2018 Feb 26.

PMID:
29483670
8.

In silico and preclinical drug screening identifies dasatinib as a targeted therapy for T-ALL.

Laukkanen S, Grönroos T, Pölönen P, Kuusanmäki H, Mehtonen J, Cloos J, Ossenkoppele G, Gjertsen B, Øystein B, Heckman C, Heinäniemi M, Kontro M, Lohi O.

Blood Cancer J. 2017 Sep 8;7(9):e604. doi: 10.1038/bcj.2017.87. No abstract available.

9.

Haematopoietic stem cell transplantation induces severe dysbiosis in intestinal microbiota of paediatric ALL patients.

Lähteenmäki K, Wacklin P, Taskinen M, Tuovinen E, Lohi O, Partanen J, Mättö J, Vettenranta K.

Bone Marrow Transplant. 2017 Oct;52(10):1479-1482. doi: 10.1038/bmt.2017.168. Epub 2017 Aug 7. No abstract available.

PMID:
28783141
10.

Deregulation of the non-coding genome in leukemia.

Teppo S, Heinäniemi M, Lohi O.

RNA Biol. 2017 Jul 3;14(7):827-830. doi: 10.1080/15476286.2017.1312228. Epub 2017 Apr 7.

11.

Derailed regulatory network in childhood acute leukaemia.

Lohi O, Heinäniemi M.

Acta Paediatr. 2017 Mar;106(3):359-360. doi: 10.1111/apa.13714. No abstract available.

PMID:
28186373
12.

Overexpression of PTP4A3 in ETV6-RUNX1 acute lymphoblastic leukemia.

Grönroos T, Teppo S, Mehtonen J, Laukkanen S, Liuksiala T, Nykter M, Heinäniemi M, Lohi O.

Leuk Res. 2017 Mar;54:1-6. doi: 10.1016/j.leukres.2016.12.005. Epub 2016 Dec 26.

PMID:
28063378
13.

Genome-wide repression of eRNA and target gene loci by the ETV6-RUNX1 fusion in acute leukemia.

Teppo S, Laukkanen S, Liuksiala T, Nordlund J, Oittinen M, Teittinen K, Grönroos T, St-Onge P, Sinnett D, Syvänen AC, Nykter M, Viiri K, Heinäniemi M, Lohi O.

Genome Res. 2016 Nov;26(11):1468-1477. Epub 2016 Sep 12.

14.

Transcription-coupled genetic instability marks acute lymphoblastic leukemia structural variation hotspots.

Heinäniemi M, Vuorenmaa T, Teppo S, Kaikkonen MU, Bouvy-Liivrand M, Mehtonen J, Niskanen H, Zachariadis V, Laukkanen S, Liuksiala T, Teittinen K, Lohi O.

Elife. 2016 Jul 19;5. pii: e13087. doi: 10.7554/eLife.13087.

15.

Background radiation and childhood leukemia: A nationwide register-based case-control study.

Nikkilä A, Erme S, Arvela H, Holmgren O, Raitanen J, Lohi O, Auvinen A.

Int J Cancer. 2016 Nov 1;139(9):1975-82. doi: 10.1002/ijc.30264. Epub 2016 Jul 22.

16.

Single-centre study reports a 84% five-year overall survival rate for paediatric solid tumours.

Teppo E, Penttinen J, Myöhänen O, Vettenranta K, Lohi O.

Acta Paediatr. 2016 Aug;105(8):952-8. doi: 10.1111/apa.13425. Epub 2016 Apr 24.

PMID:
27060472
17.

Residential mobility and the risk of childhood leukemia.

Järvelä L, Raitanen J, Erme S, Lohi O, Auvinen A.

Cancer Causes Control. 2016 Mar;27(3):433-43. doi: 10.1007/s10552-016-0720-y. Epub 2016 Feb 1.

PMID:
26830898
18.

Audits show that specialist paediatric training programmes are sensitive to medical, staffing and economic changes.

Lohi O, Helminen M, Korppi M.

Acta Paediatr. 2016 Jun;105(6):701-4. doi: 10.1111/apa.13330. Epub 2016 Feb 5.

PMID:
26776769
19.

Redox-dependent disulfide bond formation in SAP30L corepressor protein: Implications for structure and function.

Laitaoja M, Tossavainen H, Pihlajamaa T, Valjakka J, Viiri K, Lohi O, Permi P, Jänis J.

Protein Sci. 2016 Mar;25(3):572-86. doi: 10.1002/pro.2849. Epub 2015 Dec 10.

20.

[Solid tumors in children].

Lohi O, Jahnukainen K, Huttunen P, Taskinen M, Taskinen S, Pakarinen M, Koivusalo A, Rintala R, Kanerva J, Grönroos M, Heikinheimo M, Vettenranta K.

Duodecim. 2014;130(20):2050-9. Review. Finnish.

PMID:
25558602
21.

Burkitt lymphoma and Ewing sarcoma in a child with Williams syndrome.

Vanhapiha N, Knuutila S, Vettenranta K, Lohi O.

Pediatr Blood Cancer. 2014 Oct;61(10):1877-9. doi: 10.1002/pbc.25055. Epub 2014 Apr 19.

PMID:
24753445
22.

Novel activating STAT5B mutations as putative drivers of T-cell acute lymphoblastic leukemia.

Kontro M, Kuusanmäki H, Eldfors S, Burmeister T, Andersson EI, Bruserud O, Brümmendorf TH, Edgren H, Gjertsen BT, Itälä-Remes M, Lagström S, Lohi O, Lundán T, Martí JM, Majumder MM, Parsons A, Pemovska T, Rajala H, Vettenranta K, Kallioniemi O, Mustjoki S, Porkka K, Heckman CA.

Leukemia. 2014 Aug;28(8):1738-42. doi: 10.1038/leu.2014.89. Epub 2014 Feb 27. No abstract available.

PMID:
24573384
23.

Overexpression of SNORD114-3 marks acute promyelocytic leukemia.

Liuksiala T, Teittinen KJ, Granberg K, Heinäniemi M, Annala M, Mäki M, Nykter M, Lohi O.

Leukemia. 2014 Jan;28(1):233-6. doi: 10.1038/leu.2013.250. Epub 2013 Aug 27. No abstract available.

PMID:
23979522
24.

[Childhood leukemia].

Lohi O, Kanerva J, Taskinen M, Harila-Saari A, Rounioja S, Jahnukainen K, Lähteenmäki P, Vettenranta K.

Duodecim. 2013;129(9):939-46. Review. Finnish.

PMID:
23786106
25.

[Childhood brain tumors].

Nordfors K, Lohi O, Haapasalo H, Wigren T, Helén P, Vettenranta K, Arola M.

Duodecim. 2013;129(3):235-43. Review. Finnish.

PMID:
23457774
26.

Expression of small nucleolar RNAs in leukemic cells.

Teittinen KJ, Laiho A, Uusimäki A, Pursiheimo JP, Gyenesei A, Lohi O.

Cell Oncol (Dordr). 2013 Feb;36(1):55-63. doi: 10.1007/s13402-012-0113-5. Epub 2012 Nov 15.

PMID:
23229394
27.

[Outcome of childhood cancer in Tampere, Finland].

Palonkoski L, Lohi O, Arola M, Vettenranta K.

Duodecim. 2012;128(19):2015-20. Finnish.

PMID:
23155753
28.

The zebrafish as a model for paediatric diseases.

Lohi O, Parikka M, Rämet M.

Acta Paediatr. 2013 Feb;102(2):104-10. doi: 10.1111/j.1651-2227.2012.02835.x. Epub 2012 Sep 7. Review.

PMID:
22924984
29.

SAP30L (Sin3A-associated protein 30-like) is involved in regulation of cardiac development and hematopoiesis in zebrafish embryos.

Teittinen KJ, Grönroos T, Parikka M, Junttila S, Uusimäki A, Laiho A, Korkeamäki H, Kurppa K, Turpeinen H, Pesu M, Gyenesei A, Rämet M, Lohi O.

J Cell Biochem. 2012 Dec;113(12):3843-52. doi: 10.1002/jcb.24298.

PMID:
22821512
30.

The zebrafish as a tool in leukemia research.

Teittinen KJ, Grönroos T, Parikka M, Rämet M, Lohi O.

Leuk Res. 2012 Sep;36(9):1082-8. doi: 10.1016/j.leukres.2012.06.001. Epub 2012 Jun 27. Review.

PMID:
22749067
31.

Phosphoinositides as regulators of protein-chromatin interactions.

Viiri K, Mäki M, Lohi O.

Sci Signal. 2012 May 1;5(222):pe19. doi: 10.1126/scisignal.2002917. Review. Erratum in: Sci Signal. 2013 Nov 12;6(301):er7.

PMID:
22550339
32.

[Eosinophilic diseases of the gastrointestinal tract].

Kurppa K, Lohi O, Vornanen M, Ruuska T.

Duodecim. 2012;128(3):275-82. Review. Finnish.

PMID:
22428381
33.

Recurrent congenital fibrosarcoma with heart metastases.

Lohi O, Vornanen M, Kähkönen M, Vettenranta K, Parto K, Arola M.

J Pediatr Hematol Oncol. 2012 Jul;34(5):e202-5. doi: 10.1097/MPH.0b013e31823320e9.

PMID:
22217490
34.

[Leucopenia in children].

Lohi O, Vettenranta K.

Duodecim. 2011;127(14):1440-6. Review. Finnish.

PMID:
21888045
35.

Nucleolar proteins with altered expression in leukemic cell lines.

Teittinen KJ, Kärkkäinen P, Salonen J, Rönnholm G, Korkeamäki H, Vihinen M, Kalkkinen N, Lohi O.

Leuk Res. 2012 Feb;36(2):232-6. doi: 10.1016/j.leukres.2011.06.038. Epub 2011 Jul 23.

PMID:
21783252
36.

Structure of the 30-kDa Sin3-associated protein (SAP30) in complex with the mammalian Sin3A corepressor and its role in nucleic acid binding.

Xie T, He Y, Korkeamaki H, Zhang Y, Imhoff R, Lohi O, Radhakrishnan I.

J Biol Chem. 2011 Aug 5;286(31):27814-24. doi: 10.1074/jbc.M111.252494. Epub 2011 Jun 15.

37.

A high circulating copy number of HHV-6 due to chromosomal integration in a child with acute lymphoblastic leukemia.

Lohi O, Arola M, Lautenschlager I, Nacheva EP, Vettenranta K.

Pediatr Blood Cancer. 2010 Dec 1;55(6):1236-8. doi: 10.1002/pbc.22671.

PMID:
20589623
38.
39.

Coeliac disease autoantibodies in seminal plasma from cases with screen-detected coeliac disease.

Lohi S, Lohi O, Vierula M, Maki M, Toppari J.

Scand J Gastroenterol. 2009;44(4):509-11. doi: 10.1080/00365520802556007. No abstract available.

PMID:
19031265
40.

DNA-binding and -bending activities of SAP30L and SAP30 are mediated by a zinc-dependent module and monophosphoinositides.

Viiri KM, Jänis J, Siggers T, Heinonen TY, Valjakka J, Bulyk ML, Mäki M, Lohi O.

Mol Cell Biol. 2009 Jan;29(2):342-56. doi: 10.1128/MCB.01213-08. Epub 2008 Nov 17.

41.

Secretion of celiac disease autoantibodies after in vitro gliadin challenge is dependent on small-bowel mucosal transglutaminase 2-specific IgA deposits.

Stenman SM, Lindfors K, Korponay-Szabo IR, Lohi O, Saavalainen P, Partanen J, Haimila K, Wieser H, Mäki M, Kaukinen K.

BMC Immunol. 2008 Feb 29;9:6. doi: 10.1186/1471-2172-9-6.

42.

Alternative mRNA splicing of SAP30L regulates its transcriptional repression activity.

Korkeamäki H, Viiri K, Kukkonen MK, Mäki M, Lohi O.

FEBS Lett. 2008 Jan 23;582(2):379-84. Epub 2007 Dec 10.

43.

Increasing prevalence of coeliac disease over time.

Lohi S, Mustalahti K, Kaukinen K, Laurila K, Collin P, Rissanen H, Lohi O, Bravi E, Gasparin M, Reunanen A, Mäki M.

Aliment Pharmacol Ther. 2007 Nov 1;26(9):1217-25.

44.

Deficient activity of mammalian prolyl oligopeptidase on the immunoactive peptide digestion in coeliac disease.

Garcia-Horsman JA, Venäläinen JI, Lohi O, Auriola IS, Korponay-Szabo IR, Kaukinen K, Mäki M, Männistö PT.

Scand J Gastroenterol. 2007 May;42(5):562-71.

PMID:
17454876
45.

SAP30L interacts with members of the Sin3A corepressor complex and targets Sin3A to the nucleolus.

Viiri KM, Korkeamäki H, Kukkonen MK, Nieminen LK, Lindfors K, Peterson P, Mäki M, Kainulainen H, Lohi O.

Nucleic Acids Res. 2006 Jul 4;34(11):3288-98. Print 2006.

46.

A novel deletion in a Pearson syndrome infant with hypospadias and cleft lip and palate.

Lohi O, Kuusela AL, Arola M.

J Inherit Metab Dis. 2005;28(6):1165-6.

PMID:
16435219
47.

[Pediatric facial paralysis:is it a "bell" or "alarming bell"?].

Lohi O, Kuusela AL.

Duodecim. 2005;121(8):847-9. Finnish. No abstract available.

PMID:
15931828
48.

[Wheat to celiac disease].

Lohi O, Mäki M.

Duodecim. 2004;120(6):645-6. Finnish. No abstract available.

PMID:
15119224
49.
50.

ITAM motif in an apoptosis-receptor.

Lohi O, Lehto VP.

Apoptosis. 1998 Oct;3(5):335-6.

PMID:
14646480

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