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Items: 1 to 50 of 324

1.

Copper-catalyzed Asymmetric Silylation of Propargyl Dichlorides: Access to Enantioenriched Functionalized Allenylsilanes.

Xu Y, Liu ZL, Yang C, Xue QY, Zhao M, Shan CC, Loh TP.

Angew Chem Int Ed Engl. 2019 Sep 18. doi: 10.1002/anie.201908343. [Epub ahead of print]

PMID:
31532868
2.

The ruthenium-catalyzed C-H functionalization of enamides with isocyanates: easy entry to pyrimidin-4-ones.

Shi P, Li S, Hu LM, Wang C, Loh TP, Hu XH.

Chem Commun (Camb). 2019 Sep 12;55(74):11115-11118. doi: 10.1039/c9cc03612a.

PMID:
31461097
3.

A Ba/Pd Catalytic System Enables Dehydrative Cross-Coupling and Excellent E-Selective Wittig Reactions.

Xie P, Fu W, Cai X, Sun Z, Wu Y, Li S, Gao C, Yang X, Loh TP.

Org Lett. 2019 Aug 20. doi: 10.1021/acs.orglett.9b02623. [Epub ahead of print]

PMID:
31430163
4.

Palladium-Catalyzed Cycloaromatization/Alkylation of o-(Alkynyl)styrenes.

Li SS, Zhao M, Liu XW, Xu JL, Xu YH, Loh TP.

J Org Chem. 2019 Aug 27. doi: 10.1021/acs.joc.9b01630. [Epub ahead of print]

PMID:
31414808
5.

Two-Hour Postprandial Lipoprotein Particle Concentration Differs Between Lean and Obese Individuals.

Parvaresh Rizi E, Baig S, Loh TP, Toh SA, Khoo CM, Tai ES.

Front Physiol. 2019 Jul 16;10:856. doi: 10.3389/fphys.2019.00856. eCollection 2019.

6.

α-Amino Acetal: A Synthetic Intermediate for the Construction of Aza-Polycycles.

Liu DY, Zhu SM, Li RQ, Tian JS, Loh TP.

Org Lett. 2019 Aug 16;21(16):6357-6360. doi: 10.1021/acs.orglett.9b02240. Epub 2019 Aug 1.

PMID:
31369288
7.

Regioselective and Stereoselective Difluoromethylation of Enamides with Difluoromethyltriphenylphosphonium Bromide via Photoredox Catalysis.

Zhu TH, Zhang ZY, Tao JY, Zhao K, Loh TP.

Org Lett. 2019 Aug 2;21(15):6155-6159. doi: 10.1021/acs.orglett.9b02361. Epub 2019 Jul 24.

PMID:
31339728
8.

Iron(0)-Mediated Reformatsky Reaction for the Synthesis of β-Hydroxyl Carbonyl Compounds.

Liu XY, Li XR, Zhang C, Chu XQ, Rao W, Loh TP, Shen ZL.

Org Lett. 2019 Aug 2;21(15):5873-5878. doi: 10.1021/acs.orglett.9b01999. Epub 2019 Jul 18.

PMID:
31318222
9.

Barcoded DNA nanostructures for the multiplexed profiling of subcellular protein distribution.

Sundah NR, Ho NRY, Lim GS, Natalia A, Ding X, Liu Y, Seet JE, Chan CW, Loh TP, Shao H.

Nat Biomed Eng. 2019 Sep;3(9):684-694. doi: 10.1038/s41551-019-0417-0. Epub 2019 Jul 8.

PMID:
31285580
10.

Synthesis of Functionalized α-Vinyl Aldehydes from Enaminones.

Chen J, Guo P, Zhang J, Rong J, Sun W, Jiang Y, Loh TP.

Angew Chem Int Ed Engl. 2019 Sep 2;58(36):12674-12679. doi: 10.1002/anie.201906213. Epub 2019 Aug 1. Review.

PMID:
31278817
11.

Patient-Based Real-Time Quality Control: Review and Recommendations.

Badrick T, Bietenbeck A, Cervinski MA, Katayev A, van Rossum HH, Loh TP; International Federation of Clinical Chemistry, and Laboratory Medicine Committee on Analytical Quality.

Clin Chem. 2019 Aug;65(8):962-971. doi: 10.1373/clinchem.2019.305482. Epub 2019 Jul 1.

PMID:
31263035
12.

Manganese-Catalyzed Ring-Opening Coupling Reactions of Cyclopropanols with Enones.

Zhang YH, Zhang WW, Zhang ZY, Zhao K, Loh TP.

Org Lett. 2019 Jul 5;21(13):5101-5105. doi: 10.1021/acs.orglett.9b01703. Epub 2019 Jun 17.

PMID:
31247809
13.

Recommendations for laboratory informatics specifications needed for the application of patient-based real time quality control.

Loh TP, Cervinski MA, Katayev A, Bietenbeck A, van Rossum H, Badrick T; International Federation of Clinical Chemistry and Laboratory Medicine Committee on Analytical Quality.

Clin Chim Acta. 2019 Aug;495:625-629. doi: 10.1016/j.cca.2019.06.009. Epub 2019 Jun 10. Review.

PMID:
31194967
14.

Copper-catalyzed regiodivergent 1,4- and 1,6-conjugate silyl addition to diendioates: access to functionalized allylsilanes.

Ahmad T, Li Q, Qiu SQ, Xu JL, Xu YH, Loh TP.

Org Biomol Chem. 2019 Jun 26;17(25):6122-6126. doi: 10.1039/c9ob01086f.

PMID:
31172157
15.

Key questions about the future of laboratory medicine in the next decade of the 21st century: A report from the IFCC-Emerging Technologies Division.

Greaves RF, Bernardini S, Ferrari M, Fortina P, Gouget B, Gruson D, Lang T, Loh TP, Morris HA, Park JY, Roessler M, Yin P, Kricka LJ.

Clin Chim Acta. 2019 Aug;495:570-589. doi: 10.1016/j.cca.2019.05.021. Epub 2019 May 28.

PMID:
31145895
16.

Allylic Phosphorus Ylides Directly Generated from Alcohols with Water as the Only Byproduct.

Xie P, Fu W, Wu Y, Cai X, Sun Z, Li S, Gao C, Yang X, Loh TP.

Org Lett. 2019 Jun 7;21(11):4168-4172. doi: 10.1021/acs.orglett.9b01349. Epub 2019 May 28.

PMID:
31135163
17.

Palladium-Catalyzed Cascade Intramolecular Cyclization and Allylation of Enynoates with Allylic Alcohols.

Qiu SQ, Ahmad T, Xu YH, Loh TP.

J Org Chem. 2019 Jun 7;84(11):6729-6736. doi: 10.1021/acs.joc.9b00461. Epub 2019 May 23.

PMID:
31081618
18.

Palladium-Catalyzed Dialkylation of C-C Triple Bonds: Access to Multi-Functionalized Indenes.

Liu XW, Li SS, Dai DT, Zhao M, Shan CC, Xu YH, Loh TP.

Org Lett. 2019 May 17;21(10):3696-3700. doi: 10.1021/acs.orglett.9b01163. Epub 2019 May 9.

PMID:
31070377
19.

Genes Involved in Oxidative Stress Pathways Are Differentially Expressed in Circulating Mononuclear Cells Derived From Obese Insulin-Resistant and Lean Insulin-Sensitive Individuals Following a Single Mixed-Meal Challenge.

Baig S, Parvaresh Rizi E, Chia C, Shabeer M, Aung N, Loh TP, Magkos F, Vidal-Puig A, Seet RCS, Khoo CM, Toh SA.

Front Endocrinol (Lausanne). 2019 Apr 24;10:256. doi: 10.3389/fendo.2019.00256. eCollection 2019.

20.

Outcome-Based Critical Result Thresholds in the Adult Patient Population.

Tan EH, Yang Z, Li Y, Metz MP, Loh TP.

Am J Clin Pathol. 2019 Jul 5;152(2):177-184. doi: 10.1093/ajcp/aqz026.

PMID:
31067292
21.

Plasma Protein and MicroRNA Biomarkers of Insulin Resistance: A Network-Based Integrative -Omics Analysis.

Choi H, Koh HWL, Zhou L, Cheng H, Loh TP, Parvaresh Rizi E, Toh SA, Ronnett GV, Huang BE, Khoo CM.

Front Physiol. 2019 Apr 5;10:379. doi: 10.3389/fphys.2019.00379. eCollection 2019.

22.

Site-selective C(sp3)-H amination of thioamide with anthranils under Cp*CoIII catalysis.

Liu RH, Shan QC, Hu XH, Loh TP.

Chem Commun (Camb). 2019 May 7;55(38):5519-5522. doi: 10.1039/c9cc01715a.

PMID:
31020280
23.

Lead-Mediated Highly Diastereoselective Allylation of Aldehydes with Cyclic Allylic Halides.

Cheng BQ, Zhao SW, Song XD, Chu XQ, Rao W, Loh TP, Shen ZL.

J Org Chem. 2019 May 3;84(9):5348-5356. doi: 10.1021/acs.joc.9b00370. Epub 2019 Apr 23.

PMID:
30977647
24.

Divergent Protosilylation and Protoborylation of Polar Enynes.

Meng FF, Xue QY, Jiang B, Zhao M, Xie JH, Xu YH, Loh TP.

Org Lett. 2019 Apr 19;21(8):2932-2936. doi: 10.1021/acs.orglett.9b00995. Epub 2019 Apr 2.

PMID:
30939022
25.

Regioselective C-H Amidation of (Alkyl)arenes by Iron(II) Catalysis.

Ding Y, Zhang SY, Chen YC, Fan SX, Tian JS, Loh TP.

Org Lett. 2019 Apr 19;21(8):2736-2739. doi: 10.1021/acs.orglett.9b00697. Epub 2019 Mar 28.

PMID:
30920841
26.

Subtyping of circulating exosome-bound amyloid β reflects brain plaque deposition.

Lim CZJ, Zhang Y, Chen Y, Zhao H, Stephenson MC, Ho NRY, Chen Y, Chung J, Reilhac A, Loh TP, Chen CLH, Shao H.

Nat Commun. 2019 Mar 8;10(1):1144. doi: 10.1038/s41467-019-09030-2.

27.

Cobalt-Catalyzed N-O and C-C Bond Cleavage in 1,2-Oxazetidines: Solvent-Controlled C-H Aminomethylation and Hydroxymethylation of Heteroarenes.

Li S, Shi P, Liu RH, Hu XH, Loh TP.

Org Lett. 2019 Mar 15;21(6):1602-1606. doi: 10.1021/acs.orglett.9b00141. Epub 2019 Feb 26.

PMID:
30807182
28.

Indirect derivation of biological variation data and analytical performance specifications for therapeutic drug monitoring activities.

Chai JH, Flatman R, Teis B, Sethi SK, Badrick T, Loh TP.

Pathology. 2019 Apr;51(3):281-285. doi: 10.1016/j.pathol.2018.12.418. Epub 2019 Feb 23.

PMID:
30803737
29.

Divergent C-H Oxidative Radical Functionalization of Olefins to Install Tertiary Alkyl Motifs Enabled by Copper Catalysis.

Tian MQ, Wang C, Hu XH, Loh TP.

Org Lett. 2019 Mar 15;21(6):1607-1611. doi: 10.1021/acs.orglett.9b00142. Epub 2019 Feb 22.

PMID:
30793908
30.

Preparation of Alkyl Indium Reagents by Iodine-Catalyzed Direct Indium Insertion and Their Applications in Cross-Coupling Reactions.

Zhi ML, Chen BZ, Deng W, Chu XQ, Loh TP, Shen ZL.

J Org Chem. 2019 Mar 1;84(5):3017-3023. doi: 10.1021/acs.joc.9b00204. Epub 2019 Feb 13.

PMID:
30721056
31.

Reactions of 5-Aminoisoxazoles with α-Diazocarbonyl Compounds: Wolff Rearrangement vs N-H Insertion.

Ge Y, Sun W, Chen Y, Huang Y, Liu Z, Jiang Y, Loh TP.

J Org Chem. 2019 Mar 1;84(5):2676-2688. doi: 10.1021/acs.joc.8b02986. Epub 2019 Feb 12.

PMID:
30702883
32.

Relative criticalness of common laboratory tests for critical value reporting.

Yang Z, Tan EH, Li Y, Lim B, Metz MP, Loh TP.

J Clin Pathol. 2019 Apr;72(4):325-328. doi: 10.1136/jclinpath-2018-205549. Epub 2018 Dec 28.

PMID:
30593460
33.

A primer on patient-based quality control techniques.

Badrick T, Cervinski M, Loh TP.

Clin Biochem. 2019 Feb;64:1-5. doi: 10.1016/j.clinbiochem.2018.12.004. Epub 2018 Dec 11. Review.

PMID:
30550876
34.

Commutable whole blood reference materials for hemoglobin A1c validated on multiple clinical analyzers.

Liu H, Wong L, Yong S, Liu Q, Teo TL, Lee TK, Loh TP, Sethi SK, Wong MS, Cosio SMDS, Ho CKM, Setoh JWS, Lim SFM, Lee GLL, Khalid H, Lim S, Lam CW, Lee MY, Yeo CP, Chincholkar PR, Hawkins R, Ng BY.

Clin Chem Lab Med. 2019 Apr 24;57(5):648-658. doi: 10.1515/cclm-2018-0861.

PMID:
30543519
35.

Hemoglobin A1c Levels Are Slightly but Significantly Lower in Normoglycemic Subjects With the Hemoglobin E Phenotype.

Pratumvinit B, Reesukumal K, Hanyongyuth S, Wangchaijaroenkit S, Pooliam J, Kost GJ, Kamkang P, Loh TP.

Ann Lab Med. 2019 Mar;39(2):209-213. doi: 10.3343/alm.2019.39.2.209.

36.

Synthesis of Polyaromatic Rings: Rh(III)-Catalyzed [5 + 1] Annulation of Enaminones with Vinyl Esters through C-H Bond Functionalization.

Liang G, Rong J, Sun W, Chen G, Jiang Y, Loh TP.

Org Lett. 2018 Nov 16;20(22):7326-7331. doi: 10.1021/acs.orglett.8b03284. Epub 2018 Nov 7.

PMID:
30403359
37.

Polycyclic heteroaromatic ring construction driven by silver/cobalt co-catalyzed desulfonylative and defluorinative fragment-recombination of enol nonaflates with amidines.

Xie T, Zhang YW, Liu LL, Shen ZL, Loh TP, Chu XQ.

Chem Commun (Camb). 2018 Nov 8;54(90):12722-12725. doi: 10.1039/c8cc07409g.

PMID:
30357236
38.

Palladium-Catalyzed One-Pot Highly Regioselective 6- Endo Cyclization and Alkylation of Enynoates: Synthesis of 2-Alkanone Pyrones.

Ahmad T, Qiu SQ, Xu YH, Loh TP.

J Org Chem. 2018 Nov 2;83(21):13414-13426. doi: 10.1021/acs.joc.8b02198. Epub 2018 Oct 24.

PMID:
30354107
39.

Correction: A knowledge, attitude, and practice survey on mediation among clinicians in a tertiary-care hospital in Singapore.

Lin W, Ling ZJ, Liu S, Lee JTB, Lim M, Goh A, Lim S, Manning PG, Feng M, Loh TP.

PLoS One. 2018 Oct 4;13(10):e0205451. doi: 10.1371/journal.pone.0205451. eCollection 2018.

40.

Barium-catalyzed C-OH/P-H dehydrative cross-coupling for C-P bond construction.

Wo X, Xie P, Fu W, Gao C, Liu Y, Sun Z, Loh TP.

Chem Commun (Camb). 2018 Oct 2;54(79):11132-11135. doi: 10.1039/c8cc06530f.

PMID:
30225501
41.
42.

MS-based lipidomics of human blood plasma: a community-initiated position paper to develop accepted guidelines.

Burla B, Arita M, Arita M, Bendt AK, Cazenave-Gassiot A, Dennis EA, Ekroos K, Han X, Ikeda K, Liebisch G, Lin MK, Loh TP, Meikle PJ, Orešič M, Quehenberger O, Shevchenko A, Torta F, Wakelam MJO, Wheelock CE, Wenk MR.

J Lipid Res. 2018 Oct;59(10):2001-2017. doi: 10.1194/jlr.S087163. Epub 2018 Aug 16.

43.

Chromium(III)-Catalyzed Addition of Water and Alcohol to α,β-Unsaturated Ketones for the Synthesis of β-Hydroxyl and β-Alkoxyl Ketones in Aqueous Media.

Yun JJ, Liu XY, Deng W, Chu XQ, Shen ZL, Loh TP.

J Org Chem. 2018 Sep 21;83(18):10898-10907. doi: 10.1021/acs.joc.8b01584. Epub 2018 Aug 27.

PMID:
30110165
44.

Direct Substitution of Secondary and Tertiary Alcohols To Generate Sulfones under Catalyst- and Additive-Free Conditions.

Liu Y, Xie P, Sun Z, Wo X, Gao C, Fu W, Loh TP.

Org Lett. 2018 Sep 7;20(17):5353-5356. doi: 10.1021/acs.orglett.8b02188. Epub 2018 Aug 14.

PMID:
30106300
45.

Visual and modular detection of pathogen nucleic acids with enzyme-DNA molecular complexes.

Ho NRY, Lim GS, Sundah NR, Lim D, Loh TP, Shao H.

Nat Commun. 2018 Aug 13;9(1):3238. doi: 10.1038/s41467-018-05733-0.

46.

A knowledge, attitude, and practice survey on mediation among clinicians in a tertiary-care hospital in Singapore.

Lin W, Ling ZJ, Liu S, Lee JTB, Lim M, Goh A, Lim S, Manning PG, Feng M, Loh TP.

PLoS One. 2018 Jul 9;13(7):e0199885. doi: 10.1371/journal.pone.0199885. eCollection 2018. Erratum in: PLoS One. 2018 Oct 4;13(10):e0205451.

47.

Regioselective Copper-Catalyzed Oxidative Coupling of α-Alkylated Styrenes with Tertiary Alkyl Radicals.

Wang C, Liu RH, Tian MQ, Hu XH, Loh TP.

Org Lett. 2018 Jul 6;20(13):4032-4035. doi: 10.1021/acs.orglett.8b01600. Epub 2018 Jun 26.

PMID:
29943570
48.

Palladium-Catalyzed Regiocontrollable Reductive Heck Reaction of Unactivated Aliphatic Alkenes.

Wang C, Xiao G, Guo T, Ding Y, Wu X, Loh TP.

J Am Chem Soc. 2018 Aug 1;140(30):9332-9336. doi: 10.1021/jacs.8b03619. Epub 2018 Jun 22.

PMID:
29925236
49.

Palladium-Catalyzed Regioselective Olefination of O-Acetyl Cyanohydrins.

Liang QJ, Jiang B, Xu YH, Loh TP.

J Org Chem. 2018 Aug 3;83(15):8265-8271. doi: 10.1021/acs.joc.8b00991. Epub 2018 Jul 2.

PMID:
29902382
50.

Regioselective Formal [4 + 2] Cycloadditions of Enaminones with Diazocarbonyls through RhIII-Catalyzed C-H Bond Functionalization.

Zhou S, Yan BW, Fan SX, Tian JS, Loh TP.

Org Lett. 2018 Jul 6;20(13):3975-3979. doi: 10.1021/acs.orglett.8b01540. Epub 2018 Jun 11.

PMID:
29888603

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