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Items: 1 to 50 of 316

1.

Barcoded DNA nanostructures for the multiplexed profiling of subcellular protein distribution.

Sundah NR, Ho NRY, Lim GS, Natalia A, Ding X, Liu Y, Seet JE, Chan CW, Loh TP, Shao H.

Nat Biomed Eng. 2019 Jul 8. doi: 10.1038/s41551-019-0417-0. [Epub ahead of print]

PMID:
31285580
2.

Catalytic Synthesis of Functionalized α-Vinyl Aldehydes from Enaminones.

Chen J, Guo P, Zhang J, Rong J, Sun W, Jiang Y, Loh TP.

Angew Chem Int Ed Engl. 2019 Jul 6. doi: 10.1002/anie.201906213. [Epub ahead of print]

PMID:
31278817
3.

Patient-Based Real-Time Quality Control: Review and Recommendations.

Badrick T, Bietenbeck A, Cervinski MA, Katayev A, van Rossum HH, Loh TP; International Federation of Clinical Chemistry, and Laboratory Medicine Committee on Analytical Quality.

Clin Chem. 2019 Jul 1. pii: clinchem.2019.305482. doi: 10.1373/clinchem.2019.305482. [Epub ahead of print]

PMID:
31263035
4.

Manganese-Catalyzed Ring-Opening Coupling Reactions of Cyclopropanols with Enones.

Zhang YH, Zhang WW, Zhang ZY, Zhao K, Loh TP.

Org Lett. 2019 Jul 5;21(13):5101-5105. doi: 10.1021/acs.orglett.9b01703. Epub 2019 Jun 17.

PMID:
31247809
5.

Recommendations for laboratory informatics specifications needed for the application of patient-based real time quality control.

Loh TP, Cervinski MA, Katayev A, Bietenbeck A, van Rossum H, Badrick T; International Federation of Clinical Chemistry and Laboratory Medicine Committee on Analytical Quality.

Clin Chim Acta. 2019 Aug;495:625-629. doi: 10.1016/j.cca.2019.06.009. Epub 2019 Jun 10. Review.

PMID:
31194967
6.

Copper-catalyzed regiodivergent 1,4- and 1,6-conjugate silyl addition to diendioates: access to functionalized allylsilanes.

Ahmad T, Li Q, Qiu SQ, Xu JL, Xu YH, Loh TP.

Org Biomol Chem. 2019 Jun 26;17(25):6122-6126. doi: 10.1039/c9ob01086f.

PMID:
31172157
7.

Key questions about the future of laboratory medicine in the next decade of the 21st century: A report from the IFCC-Emerging Technologies Division.

Greaves RF, Bernardini S, Ferrari M, Fortina P, Gouget B, Gruson D, Lang T, Loh TP, Morris HA, Park JY, Roessler M, Yin P, Kricka LJ.

Clin Chim Acta. 2019 Aug;495:570-589. doi: 10.1016/j.cca.2019.05.021. Epub 2019 May 28.

PMID:
31145895
8.

Allylic Phosphorus Ylides Directly Generated from Alcohols with Water as the Only Byproduct.

Xie P, Fu W, Wu Y, Cai X, Sun Z, Li S, Gao C, Yang X, Loh TP.

Org Lett. 2019 Jun 7;21(11):4168-4172. doi: 10.1021/acs.orglett.9b01349. Epub 2019 May 28.

PMID:
31135163
9.

Palladium-Catalyzed Cascade Intramolecular Cyclization and Allylation of Enynoates with Allylic Alcohols.

Qiu SQ, Ahmad T, Xu YH, Loh TP.

J Org Chem. 2019 Jun 7;84(11):6729-6736. doi: 10.1021/acs.joc.9b00461. Epub 2019 May 23.

PMID:
31081618
10.

Palladium-Catalyzed Dialkylation of C-C Triple Bonds: Access to Multi-Functionalized Indenes.

Liu XW, Li SS, Dai DT, Zhao M, Shan CC, Xu YH, Loh TP.

Org Lett. 2019 May 17;21(10):3696-3700. doi: 10.1021/acs.orglett.9b01163. Epub 2019 May 9.

PMID:
31070377
11.

Genes Involved in Oxidative Stress Pathways Are Differentially Expressed in Circulating Mononuclear Cells Derived From Obese Insulin-Resistant and Lean Insulin-Sensitive Individuals Following a Single Mixed-Meal Challenge.

Baig S, Parvaresh Rizi E, Chia C, Shabeer M, Aung N, Loh TP, Magkos F, Vidal-Puig A, Seet RCS, Khoo CM, Toh SA.

Front Endocrinol (Lausanne). 2019 Apr 24;10:256. doi: 10.3389/fendo.2019.00256. eCollection 2019.

12.

Outcome-Based Critical Result Thresholds in the Adult Patient Population.

Tan EH, Yang Z, Li Y, Metz MP, Loh TP.

Am J Clin Pathol. 2019 Jul 5;152(2):177-184. doi: 10.1093/ajcp/aqz026.

PMID:
31067292
13.

Plasma Protein and MicroRNA Biomarkers of Insulin Resistance: A Network-Based Integrative -Omics Analysis.

Choi H, Koh HWL, Zhou L, Cheng H, Loh TP, Parvaresh Rizi E, Toh SA, Ronnett GV, Huang BE, Khoo CM.

Front Physiol. 2019 Apr 5;10:379. doi: 10.3389/fphys.2019.00379. eCollection 2019.

14.

Site-selective C(sp3)-H amination of thioamide with anthranils under Cp*CoIII catalysis.

Liu RH, Shan QC, Hu XH, Loh TP.

Chem Commun (Camb). 2019 May 7;55(38):5519-5522. doi: 10.1039/c9cc01715a.

PMID:
31020280
15.

Lead-Mediated Highly Diastereoselective Allylation of Aldehydes with Cyclic Allylic Halides.

Cheng BQ, Zhao SW, Song XD, Chu XQ, Rao W, Loh TP, Shen ZL.

J Org Chem. 2019 May 3;84(9):5348-5356. doi: 10.1021/acs.joc.9b00370. Epub 2019 Apr 23.

PMID:
30977647
16.

Divergent Protosilylation and Protoborylation of Polar Enynes.

Meng FF, Xue QY, Jiang B, Zhao M, Xie JH, Xu YH, Loh TP.

Org Lett. 2019 Apr 19;21(8):2932-2936. doi: 10.1021/acs.orglett.9b00995. Epub 2019 Apr 2.

PMID:
30939022
17.

Regioselective C-H Amidation of (Alkyl)arenes by Iron(II) Catalysis.

Ding Y, Zhang SY, Chen YC, Fan SX, Tian JS, Loh TP.

Org Lett. 2019 Apr 19;21(8):2736-2739. doi: 10.1021/acs.orglett.9b00697. Epub 2019 Mar 28.

PMID:
30920841
18.

Subtyping of circulating exosome-bound amyloid β reflects brain plaque deposition.

Lim CZJ, Zhang Y, Chen Y, Zhao H, Stephenson MC, Ho NRY, Chen Y, Chung J, Reilhac A, Loh TP, Chen CLH, Shao H.

Nat Commun. 2019 Mar 8;10(1):1144. doi: 10.1038/s41467-019-09030-2.

19.

Cobalt-Catalyzed N-O and C-C Bond Cleavage in 1,2-Oxazetidines: Solvent-Controlled C-H Aminomethylation and Hydroxymethylation of Heteroarenes.

Li S, Shi P, Liu RH, Hu XH, Loh TP.

Org Lett. 2019 Mar 15;21(6):1602-1606. doi: 10.1021/acs.orglett.9b00141. Epub 2019 Feb 26.

PMID:
30807182
20.

Indirect derivation of biological variation data and analytical performance specifications for therapeutic drug monitoring activities.

Chai JH, Flatman R, Teis B, Sethi SK, Badrick T, Loh TP.

Pathology. 2019 Apr;51(3):281-285. doi: 10.1016/j.pathol.2018.12.418. Epub 2019 Feb 23.

PMID:
30803737
21.

Divergent C-H Oxidative Radical Functionalization of Olefins to Install Tertiary Alkyl Motifs Enabled by Copper Catalysis.

Tian MQ, Wang C, Hu XH, Loh TP.

Org Lett. 2019 Mar 15;21(6):1607-1611. doi: 10.1021/acs.orglett.9b00142. Epub 2019 Feb 22.

PMID:
30793908
22.

Preparation of Alkyl Indium Reagents by Iodine-Catalyzed Direct Indium Insertion and Their Applications in Cross-Coupling Reactions.

Zhi ML, Chen BZ, Deng W, Chu XQ, Loh TP, Shen ZL.

J Org Chem. 2019 Mar 1;84(5):3017-3023. doi: 10.1021/acs.joc.9b00204. Epub 2019 Feb 13.

PMID:
30721056
23.

Reactions of 5-Aminoisoxazoles with α-Diazocarbonyl Compounds: Wolff Rearrangement vs N-H Insertion.

Ge Y, Sun W, Chen Y, Huang Y, Liu Z, Jiang Y, Loh TP.

J Org Chem. 2019 Mar 1;84(5):2676-2688. doi: 10.1021/acs.joc.8b02986. Epub 2019 Feb 12.

PMID:
30702883
24.

Relative criticalness of common laboratory tests for critical value reporting.

Yang Z, Tan EH, Li Y, Lim B, Metz MP, Loh TP.

J Clin Pathol. 2019 Apr;72(4):325-328. doi: 10.1136/jclinpath-2018-205549. Epub 2018 Dec 28.

PMID:
30593460
25.

A primer on patient-based quality control techniques.

Badrick T, Cervinski M, Loh TP.

Clin Biochem. 2019 Feb;64:1-5. doi: 10.1016/j.clinbiochem.2018.12.004. Epub 2018 Dec 11. Review.

PMID:
30550876
26.

Commutable whole blood reference materials for hemoglobin A1c validated on multiple clinical analyzers.

Liu H, Wong L, Yong S, Liu Q, Teo TL, Lee TK, Loh TP, Sethi SK, Wong MS, Cosio SMDS, Ho CKM, Setoh JWS, Lim SFM, Lee GLL, Khalid H, Lim S, Lam CW, Lee MY, Yeo CP, Chincholkar PR, Hawkins R, Ng BY.

Clin Chem Lab Med. 2019 Apr 24;57(5):648-658. doi: 10.1515/cclm-2018-0861.

PMID:
30543519
27.

Hemoglobin A1c Levels Are Slightly but Significantly Lower in Normoglycemic Subjects With the Hemoglobin E Phenotype.

Pratumvinit B, Reesukumal K, Hanyongyuth S, Wangchaijaroenkit S, Pooliam J, Kost GJ, Kamkang P, Loh TP.

Ann Lab Med. 2019 Mar;39(2):209-213. doi: 10.3343/alm.2019.39.2.209.

28.

Synthesis of Polyaromatic Rings: Rh(III)-Catalyzed [5 + 1] Annulation of Enaminones with Vinyl Esters through C-H Bond Functionalization.

Liang G, Rong J, Sun W, Chen G, Jiang Y, Loh TP.

Org Lett. 2018 Nov 16;20(22):7326-7331. doi: 10.1021/acs.orglett.8b03284. Epub 2018 Nov 7.

PMID:
30403359
29.

Polycyclic heteroaromatic ring construction driven by silver/cobalt co-catalyzed desulfonylative and defluorinative fragment-recombination of enol nonaflates with amidines.

Xie T, Zhang YW, Liu LL, Shen ZL, Loh TP, Chu XQ.

Chem Commun (Camb). 2018 Nov 8;54(90):12722-12725. doi: 10.1039/c8cc07409g.

PMID:
30357236
30.

Palladium-Catalyzed One-Pot Highly Regioselective 6- Endo Cyclization and Alkylation of Enynoates: Synthesis of 2-Alkanone Pyrones.

Ahmad T, Qiu SQ, Xu YH, Loh TP.

J Org Chem. 2018 Nov 2;83(21):13414-13426. doi: 10.1021/acs.joc.8b02198. Epub 2018 Oct 24.

PMID:
30354107
31.

Correction: A knowledge, attitude, and practice survey on mediation among clinicians in a tertiary-care hospital in Singapore.

Lin W, Ling ZJ, Liu S, Lee JTB, Lim M, Goh A, Lim S, Manning PG, Feng M, Loh TP.

PLoS One. 2018 Oct 4;13(10):e0205451. doi: 10.1371/journal.pone.0205451. eCollection 2018.

32.

Barium-catalyzed C-OH/P-H dehydrative cross-coupling for C-P bond construction.

Wo X, Xie P, Fu W, Gao C, Liu Y, Sun Z, Loh TP.

Chem Commun (Camb). 2018 Oct 2;54(79):11132-11135. doi: 10.1039/c8cc06530f.

PMID:
30225501
33.
34.

MS-based lipidomics of human blood plasma: a community-initiated position paper to develop accepted guidelines.

Burla B, Arita M, Arita M, Bendt AK, Cazenave-Gassiot A, Dennis EA, Ekroos K, Han X, Ikeda K, Liebisch G, Lin MK, Loh TP, Meikle PJ, Orešič M, Quehenberger O, Shevchenko A, Torta F, Wakelam MJO, Wheelock CE, Wenk MR.

J Lipid Res. 2018 Oct;59(10):2001-2017. doi: 10.1194/jlr.S087163. Epub 2018 Aug 16.

35.

Chromium(III)-Catalyzed Addition of Water and Alcohol to α,β-Unsaturated Ketones for the Synthesis of β-Hydroxyl and β-Alkoxyl Ketones in Aqueous Media.

Yun JJ, Liu XY, Deng W, Chu XQ, Shen ZL, Loh TP.

J Org Chem. 2018 Sep 21;83(18):10898-10907. doi: 10.1021/acs.joc.8b01584. Epub 2018 Aug 27.

PMID:
30110165
36.

Direct Substitution of Secondary and Tertiary Alcohols To Generate Sulfones under Catalyst- and Additive-Free Conditions.

Liu Y, Xie P, Sun Z, Wo X, Gao C, Fu W, Loh TP.

Org Lett. 2018 Sep 7;20(17):5353-5356. doi: 10.1021/acs.orglett.8b02188. Epub 2018 Aug 14.

PMID:
30106300
37.

Visual and modular detection of pathogen nucleic acids with enzyme-DNA molecular complexes.

Ho NRY, Lim GS, Sundah NR, Lim D, Loh TP, Shao H.

Nat Commun. 2018 Aug 13;9(1):3238. doi: 10.1038/s41467-018-05733-0.

38.

A knowledge, attitude, and practice survey on mediation among clinicians in a tertiary-care hospital in Singapore.

Lin W, Ling ZJ, Liu S, Lee JTB, Lim M, Goh A, Lim S, Manning PG, Feng M, Loh TP.

PLoS One. 2018 Jul 9;13(7):e0199885. doi: 10.1371/journal.pone.0199885. eCollection 2018. Erratum in: PLoS One. 2018 Oct 4;13(10):e0205451.

39.

Regioselective Copper-Catalyzed Oxidative Coupling of α-Alkylated Styrenes with Tertiary Alkyl Radicals.

Wang C, Liu RH, Tian MQ, Hu XH, Loh TP.

Org Lett. 2018 Jul 6;20(13):4032-4035. doi: 10.1021/acs.orglett.8b01600. Epub 2018 Jun 26.

PMID:
29943570
40.

Palladium-Catalyzed Regiocontrollable Reductive Heck Reaction of Unactivated Aliphatic Alkenes.

Wang C, Xiao G, Guo T, Ding Y, Wu X, Loh TP.

J Am Chem Soc. 2018 Aug 1;140(30):9332-9336. doi: 10.1021/jacs.8b03619. Epub 2018 Jun 22.

PMID:
29925236
41.

Palladium-Catalyzed Regioselective Olefination of O-Acetyl Cyanohydrins.

Liang QJ, Jiang B, Xu YH, Loh TP.

J Org Chem. 2018 Aug 3;83(15):8265-8271. doi: 10.1021/acs.joc.8b00991. Epub 2018 Jul 2.

PMID:
29902382
42.

Regioselective Formal [4 + 2] Cycloadditions of Enaminones with Diazocarbonyls through RhIII-Catalyzed C-H Bond Functionalization.

Zhou S, Yan BW, Fan SX, Tian JS, Loh TP.

Org Lett. 2018 Jul 6;20(13):3975-3979. doi: 10.1021/acs.orglett.8b01540. Epub 2018 Jun 11.

PMID:
29888603
43.

Evaluation of the Luminex ARIES HSV 1&2 Assay and Comparison with the FTD Neuro 9 and In-house Real-Time PCR Assays for Detecting Herpes Simplex Viruses.

Lee CK, Chai CN, Capinpin SM, Ang A, Ng SY, Lee PL, Ng CWS, Yan G, Lee HK, Chiu LL, Jureen R, Yan B, Loh TP.

Ann Lab Med. 2018 Sep;38(5):440-445. doi: 10.3343/alm.2018.38.5.440.

44.

Copper-Catalyzed Dehydrogenative Diels-Alder Reaction.

Jiang B, Liang QJ, Han Y, Zhao M, Xu YH, Loh TP.

Org Lett. 2018 Jun 1;20(11):3215-3219. doi: 10.1021/acs.orglett.8b01067. Epub 2018 May 23.

PMID:
29790760
45.

Bronsted Acid/Organic Photoredox Cooperative Catalysis: Easy Access to Tri- and Tetrasubstituted Alkenylphosphorus Compounds from Alcohols and P-H Species.

Xie P, Fan J, Liu Y, Wo X, Fu W, Loh TP.

Org Lett. 2018 Jun 1;20(11):3341-3344. doi: 10.1021/acs.orglett.8b01173. Epub 2018 May 21.

PMID:
29781271
46.

Rh-Catalyzed C-H bond alkylation of indoles with α,α-difluorovinyl tosylate via indolyl group migration.

Zhou L, Zhu C, Loh TP, Feng C.

Chem Commun (Camb). 2018 May 29;54(44):5618-5621. doi: 10.1039/c8cc02183j.

PMID:
29770372
47.

Hoveyda-Grubbs II Catalyst: A Useful Catalyst for One-Pot Visible-Light-Promoted Ring Contraction and Olefin Metathesis Reactions.

Ge Y, Sun W, Pei B, Ding J, Jiang Y, Loh TP.

Org Lett. 2018 May 4;20(9):2774-2777. doi: 10.1021/acs.orglett.8b00971. Epub 2018 Apr 25.

PMID:
29693396
48.

In(III)-TMSBr-Catalyzed Cascade Reaction of Diarylalkynes with Acrylates for the Synthesis of Aryldihydronaphthalene Derivatives.

Zhang QC, Zhang WW, Shen L, Shen ZL, Loh TP.

Molecules. 2018 Apr 23;23(4). pii: E979. doi: 10.3390/molecules23040979.

49.

Combining Fluoroalkylation and Defluorination to Enable Formal [3 + 2 + 1] Heteroannulation by Using Visible-Light Photoredox Organocatalysis.

Chu XQ, Xie T, Li L, Ge D, Shen ZL, Loh TP.

Org Lett. 2018 May 4;20(9):2749-2752. doi: 10.1021/acs.orglett.8b00963. Epub 2018 Apr 23.

PMID:
29683679
50.

Indirect methods for reference interval determination - review and recommendations.

Jones GRD, Haeckel R, Loh TP, Sikaris K, Streichert T, Katayev A, Barth JH, Ozarda Y; IFCC Committee on Reference Intervals and Decision Limits.

Clin Chem Lab Med. 2018 Dec 19;57(1):20-29. doi: 10.1515/cclm-2018-0073.

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