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Items: 1 to 50 of 330

1.

Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

Kichaev G, Bhatia G, Loh PR, Gazal S, Burch K, Freund MK, Schoech A, Pasaniuc B, Price AL.

Am J Hum Genet. 2019 Jan 3;104(1):65-75. doi: 10.1016/j.ajhg.2018.11.008. Epub 2018 Dec 27.

PMID:
30595370
2.

Occlusal schemes for complete dentures.

Loh PJ, Levey C.

Evid Based Dent. 2018 Dec;19(4):116-117. doi: 10.1038/sj.ebd.6401346.

PMID:
30573857
3.

Evaluation of Changes in the Motor Network Following BCI Therapy Based on Graph Theory Analysis.

Mazrooyisebdani M, Nair VA, Loh PL, Remsik AB, Young BM, Moreno BS, Dodd KC, Kang TJ, William JC, Prabhakaran V.

Front Neurosci. 2018 Nov 27;12:861. doi: 10.3389/fnins.2018.00861. eCollection 2018.

4.

Multivessel coronary artery spasm in pericarditis.

Lim Y, Singh D, Loh PH, Poh KK.

Singapore Med J. 2018 Nov;59(11):611-613. doi: 10.11622/smedj.2018138. No abstract available.

5.

Estimating cross-population genetic correlations of causal effect sizes.

Galinsky KJ, Reshef YA, Finucane HK, Loh PR, Zaitlen N, Patterson NJ, Brown BC, Price AL.

Genet Epidemiol. 2018 Nov 25. doi: 10.1002/gepi.22173. [Epub ahead of print]

PMID:
30474154
6.

Antiemetic doses of dexamethasone and their effects on immune cell populations and plasma mediators of inflammation resolution in healthy volunteers.

Barden A, Phillips M, Hill LM, Fletcher EM, Mas E, Loh PS, French MA, Ho KM, Mori TA, Corcoran TB.

Prostaglandins Leukot Essent Fatty Acids. 2018 Dec;139:31-39. doi: 10.1016/j.plefa.2018.11.004. Epub 2018 Nov 8.

PMID:
30471772
7.

Clinical outcomes one year and beyond after combination sirolimus eluting endothelial progenitor cell capture stenting during primary percutaneous coronary intervention in ST-segment elevation myocardial infarction.

Sim HW, Thong EH, Tan HC, Low AF, Lee CH, Chan MY, Tay EL, Loh PH, Chan KH, Loh JP.

Cardiovasc Revasc Med. 2018 Nov 7. pii: S1553-8389(18)30493-7. doi: 10.1016/j.carrev.2018.11.004. [Epub ahead of print]

PMID:
30442536
8.

Author Correction: A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

Zhu Z, Lee PH, Chaffin MD, Chung W, Loh PR, Lu Q, Christiani DC, Liang L.

Nat Genet. 2018 Dec;50(12):1753. doi: 10.1038/s41588-018-0284-8.

PMID:
30390058
9.

Atrial Dysfunction in Arrhythmogenic Right Ventricular Cardiomyopathy.

Zghaib T, Bourfiss M, van der Heijden JF, Loh P, Hauer RN, Tandri H, Calkins H, Nazarian S, Te Riele ASJM, Zimmerman SL, Velthuis BK.

Circ Cardiovasc Imaging. 2018 Sep;11(9):e007344. doi: 10.1161/CIRCIMAGING.117.007344.

PMID:
30354672
10.

Takotsubo hypertrophic obstructive cardiomyopathy and bicuspid valvulopathy: implication of multiple imaging modalities.

Kong WK, Loh PH, Teo L, Ong CC, Wong RC.

Eur Heart J. 2018 Oct 17. doi: 10.1093/eurheartj/ehy673. [Epub ahead of print] No abstract available.

PMID:
30339220
11.

Functional architecture of low-frequency variants highlights strength of negative selection across coding and non-coding annotations.

Gazal S, Loh PR, Finucane HK, Ganna A, Schoech A, Sunyaev S, Price AL.

Nat Genet. 2018 Nov;50(11):1600-1607. doi: 10.1038/s41588-018-0231-8. Epub 2018 Oct 8.

PMID:
30297966
12.

Detecting genome-wide directional effects of transcription factor binding on polygenic disease risk.

Reshef YA, Finucane HK, Kelley DR, Gusev A, Kotliar D, Ulirsch JC, Hormozdiari F, Nasser J, O'Connor L, van de Geijn B, Loh PR, Grossman SR, Bhatia G, Gazal S, Palamara PF, Pinello L, Patterson N, Adams RP, Price AL.

Nat Genet. 2018 Oct;50(10):1483-1493. doi: 10.1038/s41588-018-0196-7. Epub 2018 Sep 3.

PMID:
30177862
13.

Deformation of the median nerve at different finger postures and wrist angles.

Loh PY, Yeoh WL, Nakashima H, Muraki S.

PeerJ. 2018 Aug 9;6:e5406. doi: 10.7717/peerj.5406. eCollection 2018.

14.

An Unexpected Cause of Trauma-related Myocardial Infarction: Multimodality Assessment of Right Coronary Artery Dissection.

Ngam PI, Ong CC, Koo CC, Loh PH, Loo LM, Teo LL.

Ann Acad Med Singapore. 2018 Jul;47(7):269-271. No abstract available.

15.

Insights into clonal haematopoiesis from 8,342 mosaic chromosomal alterations.

Loh PR, Genovese G, Handsaker RE, Finucane HK, Reshef YA, Palamara PF, Birmann BM, Talkowski ME, Bakhoum SF, McCarroll SA, Price AL.

Nature. 2018 Jul;559(7714):350-355. doi: 10.1038/s41586-018-0321-x. Epub 2018 Jul 11.

16.

Rationale and design for the detection and neurological impact of cerebrovascular events in non-cardiac surgery patients cohort evaluation (NeuroVISION) study: a prospective international cohort study.

Mrkobrada M, Chan MTV, Cowan D, Spence J, Campbell D, Wang CY, Torres D, Malaga G, Sanders RD, Brown C, Sigamani A, Szczeklik W, Dmytriw AA, Agid R, Smith EE, Hill MD, Sharma M, Sharma M, Tsai S, Mensinkai A, Sahlas DJ, Guyatt G, Pettit S, Copland I, Wu WKK, Yu SCH, Gin T, Loh PS, Ramli N, Siow YL, Short TG, Waymouth E, Kumar J, Dasgupta M, Murkin JM, Fuentes M, Ortiz-Soriano V, Lindroth H, Simpson S, Sessler D, Devereaux PJ.

BMJ Open. 2018 Jul 6;8(7):e021521. doi: 10.1136/bmjopen-2018-021521.

17.

Leveraging molecular quantitative trait loci to understand the genetic architecture of diseases and complex traits.

Hormozdiari F, Gazal S, van de Geijn B, Finucane HK, Ju CJ, Loh PR, Schoech A, Reshef Y, Liu X, O'Connor L, Gusev A, Eskin E, Price AL.

Nat Genet. 2018 Jul;50(7):1041-1047. doi: 10.1038/s41588-018-0148-2. Epub 2018 Jun 25.

18.

Mixed-model association for biobank-scale datasets.

Loh PR, Kichaev G, Gazal S, Schoech AP, Price AL.

Nat Genet. 2018 Jul;50(7):906-908. doi: 10.1038/s41588-018-0144-6. No abstract available.

19.

RNA Structure Design Improves Activity and Specificity of trans-Splicing-Triggered Cell Death in a Suicide Gene Therapy Approach.

Poddar S, Loh PS, Ooi ZH, Osman F, Eul J, Patzel V.

Mol Ther Nucleic Acids. 2018 Jun 1;11:41-56. doi: 10.1016/j.omtn.2018.01.006. Epub 2018 Jan 31.

20.

A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

Zhu Z, Lee PH, Chaffin MD, Chung W, Loh PR, Lu Q, Christiani DC, Liang L.

Nat Genet. 2018 Jun;50(6):857-864. doi: 10.1038/s41588-018-0121-0. Epub 2018 May 21. Erratum in: Nat Genet. 2018 Dec;50(12):1753.

21.

Incidence of Pulmonary Vein Stenosis After Radiofrequency Catheter Ablation of Atrial Fibrillation.

Teunissen C, Velthuis BK, Hassink RJ, van der Heijden JF, Vonken EPA, Clappers N, Doevendans PA, Loh P.

JACC Clin Electrophysiol. 2017 Jun;3(6):589-598. doi: 10.1016/j.jacep.2017.02.003. Epub 2017 Apr 26.

22.

Intra-operative cell salvage and sickle cell trait in liver transplantation: time to reconsider?

Loh PS, Gilder F, Klinck J.

Transpl Int. 2018 Jul;31(7):781-782. doi: 10.1111/tri.13268. Epub 2018 May 11. No abstract available.

PMID:
29672993
23.

Treatment of Very Small De Novo Coronary Artery Disease With 2.0 mm Drug-Coated Balloons Showed 1-Year Clinical Outcome Comparable With 2.0 mm Drug-Eluting Stents.

Sim HW, Ananthakrishna R, Chan SP, Low AF, Lee CH, Chan MY, Tay EL, Loh PH, Chan KH, Tan HC, Loh JP.

J Invasive Cardiol. 2018 Jul;30(7):256-261. Epub 2018 Apr 15.

24.

Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types.

Finucane HK, Reshef YA, Anttila V, Slowikowski K, Gusev A, Byrnes A, Gazal S, Loh PR, Lareau C, Shoresh N, Genovese G, Saunders A, Macosko E, Pollack S; Brainstorm Consortium, Perry JRB, Buenrostro JD, Bernstein BE, Raychaudhuri S, McCarroll S, Neale BM, Price AL.

Nat Genet. 2018 Apr;50(4):621-629. doi: 10.1038/s41588-018-0081-4. Epub 2018 Apr 9.

25.

Incidence and predictors of target lesion failure in a multiethnic Asian population receiving the SYNERGY coronary stent: A prospective all-comers registry.

Ananthakrishna R, Kristanto W, Liu L, Chan SP, Loh PH, Tay EL, Chan KH, Chan MY, Lee CH, Low AF, Tan HC, Loh JP.

Catheter Cardiovasc Interv. 2018 Nov 15;92(6):1097-1103. doi: 10.1002/ccd.27577. Epub 2018 Mar 7.

PMID:
29513378
26.

Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness.

Willems SM, Wright DJ, Day FR, Trajanoska K, Joshi PK, Morris JA, Matteini AM, Garton FC, Grarup N, Oskolkov N, Thalamuthu A, Mangino M, Liu J, Demirkan A, Lek M, Xu L, Wang G, Oldmeadow C, Gaulton KJ, Lotta LA, Miyamoto-Mikami E, Rivas MA, White T, Loh PR, Aadahl M, Amin N, Attia JR, Austin K, Benyamin B, Brage S, Cheng YC, Cięszczyk P, Derave W, Eriksson KF, Eynon N, Linneberg A, Lucia A, Massidda M, Mitchell BD, Miyachi M, Murakami H, Padmanabhan S, Pandey A, Papadimitriou I, Rajpal DK, Sale C, Schnurr TM, Sessa F, Shrine N, Tobin MD, Varley I, Wain LV, Wray NR, Lindgren CM, MacArthur DG, Waterworth DM, McCarthy MI, Pedersen O, Khaw KT, Kiel DP; GEFOS Any-Type of Fracture Consortium, Pitsiladis Y, Fuku N, Franks PW, North KN, van Duijn CM, Mather KA, Hansen T, Hansson O, Spector T, Murabito JM, Richards JB, Rivadeneira F, Langenberg C, Perry JRB, Wareham NJ, Scott RA.

Nat Commun. 2017 Jul 12;8:16015. doi: 10.1038/ncomms16015.

27.

Heritability of Atrial Fibrillation.

Weng LC, Choi SH, Klarin D, Smith JG, Loh PR, Chaffin M, Roselli C, Hulme OL, Lunetta KL, Dupuis J, Benjamin EJ, Newton-Cheh C, Kathiresan S, Ellinor PT, Lubitz SA.

Circ Cardiovasc Genet. 2017 Dec;10(6). pii: e001838. doi: 10.1161/CIRCGENETICS.117.001838.

28.

The hemodynamic and pain impact of peripheral nerve block versus spinal anesthesia in diabetic patients undergoing diabetic foot surgery.

Lai HY, Foo LL, Lim SM, Yong CF, Loh PS, Chaw SH, Hasan MS, Wang CY.

Clin Auton Res. 2017 Dec 1. doi: 10.1007/s10286-017-0485-8. [Epub ahead of print]

PMID:
29196938
29.

Machine learning to detect signatures of disease in liquid biopsies - a user's guide.

Ko J, Baldassano SN, Loh PL, Kording K, Litt B, Issadore D.

Lab Chip. 2018 Jan 30;18(3):395-405. doi: 10.1039/c7lc00955k. Review.

PMID:
29192299
30.

Multiethnic polygenic risk scores improve risk prediction in diverse populations.

Márquez-Luna C, Loh PR; South Asian Type 2 Diabetes (SAT2D) Consortium; SIGMA Type 2 Diabetes Consortium, Price AL.

Genet Epidemiol. 2017 Dec;41(8):811-823. doi: 10.1002/gepi.22083. Epub 2017 Nov 7.

31.

Linkage disequilibrium-dependent architecture of human complex traits shows action of negative selection.

Gazal S, Finucane HK, Furlotte NA, Loh PR, Palamara PF, Liu X, Schoech A, Bulik-Sullivan B, Neale BM, Gusev A, Price AL.

Nat Genet. 2017 Oct;49(10):1421-1427. doi: 10.1038/ng.3954. Epub 2017 Sep 11.

32.

Real world experience with pegylated interferon and ribavirin in hepatitis C genotype 1 population with favourable IL28B polymorphism.

Ekstrom V, Kumar R, Zhao Y, Yee ML, Sung C, Toh D, Loh PY, Tan J, Teo EK, Chow WC.

Gastroenterol Rep (Oxf). 2017 Aug;5(3):208-212. doi: 10.1093/gastro/gow033. Epub 2016 Oct 24.

33.

Combining glidescope and fiber-optic for intubation in oral maxillofacial surgery.

Loh PS, Ng KWS.

J Anaesthesiol Clin Pharmacol. 2017 Apr-Jun;33(2):254-255. doi: 10.4103/0970-9185.209738.

34.

A decade of atrial fibrillation ablation : Shifts in patient characteristics and procedural outcomes.

Teunissen C, Clappers N, Hassink RJ, van der Heijden JF, Wittkampf FH, Loh P.

Neth Heart J. 2017 Oct;25(10):559-566. doi: 10.1007/s12471-017-1019-7.

35.

Active immunization for prevention of De novo hepatitis B virus infection after adult living donor liver transplantation with a hepatitis B core antigen-positive graft.

Wang SH, Loh PY, Lin TL, Lin LM, Li WF, Lin YH, Lin CC, Chen CL.

Liver Transpl. 2017 Oct;23(10):1266-1272. doi: 10.1002/lt.24814.

36.

Effects of immunonutrition on biomarkers in traumatic brain injury patients in Malaysia: a prospective randomized controlled trial.

Rai VRH, Phang LF, Sia SF, Amir A, Veerakumaran JS, Kassim MKA, Othman R, Tah PC, Loh PS, Jailani MIO, Ong G.

BMC Anesthesiol. 2017 Jun 15;17(1):81. doi: 10.1186/s12871-017-0369-4.

37.

Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk.

Day FR, Thompson DJ, Helgason H, Chasman DI, Finucane H, Sulem P, Ruth KS, Whalen S, Sarkar AK, Albrecht E, Altmaier E, Amini M, Barbieri CM, Boutin T, Campbell A, Demerath E, Giri A, He C, Hottenga JJ, Karlsson R, Kolcic I, Loh PR, Lunetta KL, Mangino M, Marco B, McMahon G, Medland SE, Nolte IM, Noordam R, Nutile T, Paternoster L, Perjakova N, Porcu E, Rose LM, Schraut KE, Segrè AV, Smith AV, Stolk L, Teumer A, Andrulis IL, Bandinelli S, Beckmann MW, Benitez J, Bergmann S, Bochud M, Boerwinkle E, Bojesen SE, Bolla MK, Brand JS, Brauch H, Brenner H, Broer L, Brüning T, Buring JE, Campbell H, Catamo E, Chanock S, Chenevix-Trench G, Corre T, Couch FJ, Cousminer DL, Cox A, Crisponi L, Czene K, Davey Smith G, de Geus EJCN, de Mutsert R, De Vivo I, Dennis J, Devilee P, Dos-Santos-Silva I, Dunning AM, Eriksson JG, Fasching PA, Fernández-Rhodes L, Ferrucci L, Flesch-Janys D, Franke L, Gabrielson M, Gandin I, Giles GG, Grallert H, Gudbjartsson DF, Guénel P, Hall P, Hallberg E, Hamann U, Harris TB, Hartman CA, Heiss G, Hooning MJ, Hopper JL, Hu F, Hunter DJ, Ikram MA, Im HK, Järvelin MR, Joshi PK, Karasik D, Kellis M, Kutalik Z, LaChance G, Lambrechts D, Langenberg C, Launer LJ, Laven JSE, Lenarduzzi S, Li J, Lind PA, Lindstrom S, Liu Y, Luan J, Mägi R, Mannermaa A, Mbarek H, McCarthy MI, Meisinger C, Meitinger T, Menni C, Metspalu A, Michailidou K, Milani L, Milne RL, Montgomery GW, Mulligan AM, Nalls MA, Navarro P, Nevanlinna H, Nyholt DR, Oldehinkel AJ, O'Mara TA, Padmanabhan S, Palotie A, Pedersen N, Peters A, Peto J, Pharoah PDP, Pouta A, Radice P, Rahman I, Ring SM, Robino A, Rosendaal FR, Rudan I, Rueedi R, Ruggiero D, Sala CF, Schmidt MK, Scott RA, Shah M, Sorice R, Southey MC, Sovio U, Stampfer M, Steri M, Strauch K, Tanaka T, Tikkanen E, Timpson NJ, Traglia M, Truong T, Tyrer JP, Uitterlinden AG, Edwards DRV, Vitart V, Völker U, Vollenweider P, Wang Q, Widen E, van Dijk KW, Willemsen G, Winqvist R, Wolffenbuttel BHR, Zhao JH, Zoledziewska M, Zygmunt M, Alizadeh BZ, Boomsma DI, Ciullo M, Cucca F, Esko T, Franceschini N, Gieger C, Gudnason V, Hayward C, Kraft P, Lawlor DA, Magnusson PKE, Martin NG, Mook-Kanamori DO, Nohr EA, Polasek O, Porteous D, Price AL, Ridker PM, Snieder H, Spector TD, Stöckl D, Toniolo D, Ulivi S, Visser JA, Völzke H, Wareham NJ, Wilson JF; LifeLines Cohort Study; InterAct Consortium; kConFab/AOCS Investigators; Endometrial Cancer Association Consortium; Ovarian Cancer Association Consortium; PRACTICAL consortium, Spurdle AB, Thorsteindottir U, Pollard KS, Easton DF, Tung JY, Chang-Claude J, Hinds D, Murray A, Murabito JM, Stefansson K, Ong KK, Perry JRB.

Nat Genet. 2017 Jun;49(6):834-841. doi: 10.1038/ng.3841. Epub 2017 Apr 24.

38.

Stepwise Distributed Open Innovation Contests for Software Development: Acceleration of Genome-Wide Association Analysis.

Hill A, Loh PR, Bharadwaj RB, Pons P, Shang J, Guinan E, Lakhani K, Kilty I, Jelinsky SA.

Gigascience. 2017 May 1;6(5):1-10. doi: 10.1093/gigascience/gix009.

40.

Sources and distribution of sedimentary organic matter along the northern Bering and Chukchi Seas.

Xu F, Jin H, Ji Z, Chen J, Loh PS.

J Environ Sci (China). 2017 Feb;52:66-75. doi: 10.1016/j.jes.2016.04.003. Epub 2016 Apr 27.

PMID:
28254059
41.

Evaluation of Structural Progression in Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy.

Mast TP, James CA, Calkins H, Teske AJ, Tichnell C, Murray B, Loh P, Russell SD, Velthuis BK, Judge DP, Dooijes D, Tedford RJ, van der Heijden JF, Tandri H, Hauer RN, Abraham TP, Doevendans PA, Te Riele AS, Cramer MJ.

JAMA Cardiol. 2017 Mar 1;2(3):293-302. doi: 10.1001/jamacardio.2016.5034.

PMID:
28097316
42.

Next-generation sequencing of a large gene panel in patients initially diagnosed with idiopathic ventricular fibrillation.

Visser M, Dooijes D, van der Smagt JJ, van der Heijden JF, Doevendans PA, Loh P, Asselbergs FW, Hassink RJ.

Heart Rhythm. 2017 Jul;14(7):1035-1040. doi: 10.1016/j.hrthm.2017.01.010. Epub 2017 Jan 11.

PMID:
28087426
43.

Mixed Model Association with Family-Biased Case-Control Ascertainment.

Hayeck TJ, Loh PR, Pollack S, Gusev A, Patterson N, Zaitlen NA, Price AL.

Am J Hum Genet. 2017 Jan 5;100(1):31-39. doi: 10.1016/j.ajhg.2016.11.015. Epub 2016 Dec 22.

44.

Right Ventricular Imaging and Computer Simulation for Electromechanical Substrate Characterization in Arrhythmogenic Right Ventricular Cardiomyopathy.

Mast TP, Teske AJ, Walmsley J, van der Heijden JF, van Es R, Prinzen FW, Delhaas T, van Veen TA, Loh P, Doevendans PA, Cramer MJ, Lumens J.

J Am Coll Cardiol. 2016 Nov 15;68(20):2185-2197. doi: 10.1016/j.jacc.2016.08.061.

45.

Characterization of Chlamydomonas Ribulose-1,5-bisphosphate carboxylase/oxygenase variants mutated at residues that are post-translationally modified.

Rasineni GK, Loh PC, Lim BH.

Biochim Biophys Acta Gen Subj. 2017 Feb;1861(2):79-85. doi: 10.1016/j.bbagen.2016.10.027. Epub 2016 Nov 3.

PMID:
27816753
46.

Response to Shen et al.

Galinsky KJ, Bhatia G, Loh PR, Georgiev S, Mukherjee S, Patterson NJ, Price AL.

Am J Hum Genet. 2016 Nov 3;99(5):1220-1221. doi: 10.1016/j.ajhg.2016.09.013. No abstract available.

47.

Reference-based phasing using the Haplotype Reference Consortium panel.

Loh PR, Danecek P, Palamara PF, Fuchsberger C, A Reshef Y, K Finucane H, Schoenherr S, Forer L, McCarthy S, Abecasis GR, Durbin R, L Price A.

Nat Genet. 2016 Nov;48(11):1443-1448. doi: 10.1038/ng.3679. Epub 2016 Oct 3.

48.

Population Structure of UK Biobank and Ancient Eurasians Reveals Adaptation at Genes Influencing Blood Pressure.

Galinsky KJ, Loh PR, Mallick S, Patterson NJ, Price AL.

Am J Hum Genet. 2016 Nov 3;99(5):1130-1139. doi: 10.1016/j.ajhg.2016.09.014. Epub 2016 Oct 20.

49.

Long-Term Outcome of Patients Initially Diagnosed With Idiopathic Ventricular Fibrillation: A Descriptive Study.

Visser M, van der Heijden JF, van der Smagt JJ, Doevendans PA, Wilde AA, Loh P, Hassink RJ.

Circ Arrhythm Electrophysiol. 2016 Oct;9(10). pii: e004258.

PMID:
27733492
50.

Time matters: adenosine testing immediately after pulmonary vein isolation does not substitute a waiting period.

Teunissen C, Clappers N, Kassenberg W, Hassink RJ, van der Heijden JF, Loh P.

Europace. 2017 Jul 1;19(7):1140-1145. doi: 10.1093/europace/euw173.

PMID:
27702849

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