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Items: 1 to 50 of 180

1.

Transgenic Expression of PRSS1R122H Sensitizes Mice to Pancreatitis.

Huang H, Swidnicka-Siergiejko AK, Daniluk J, Gaiser S, Yao Y, Peng L, Zhang Y, Liu Y, Dong M, Zhan X, Wang H, Bi Y, Li Z, Ji B, Logsdon CD.

Gastroenterology. 2019 Aug 13. pii: S0016-5085(19)41228-6. doi: 10.1053/j.gastro.2019.08.016. [Epub ahead of print]

2.

Oncogenic KRAS Reduces Expression of FGF21 in Acinar Cells to Promote Pancreatic Tumorigenesis in Mice on a High-Fat Diet.

Luo Y, Yang Y, Liu M, Wang D, Wang F, Bi Y, Ji J, Li S, Liu Y, Chen R, Huang H, Wang X, Swidnicka-Siergiejko AK, Janowitz T, Beyaz S, Wang G, Xu S, Bialkowska AB, Luo CK, Pin CL, Liang G, Lu X, Wu M, Shroyer KR, Wolff RA, Plunkett W, Ji B, Li Z, Li E, Li X, Yang VW, Logsdon CD, Abbruzzese JL, Lu W.

Gastroenterology. 2019 Jul 25. pii: S0016-5085(19)41127-X. doi: 10.1053/j.gastro.2019.07.030. [Epub ahead of print]

PMID:
31352001
3.

Small interfering RNAs (siRNAs) in cancer therapy: a nano-based approach.

Mahmoodi Chalbatani G, Dana H, Gharagouzloo E, Grijalvo S, Eritja R, Logsdon CD, Memari F, Miri SR, Rad MR, Marmari V.

Int J Nanomedicine. 2019 May 2;14:3111-3128. doi: 10.2147/IJN.S200253. eCollection 2019. Review.

4.

Obesogenic high-fat diet heightens aerobic glycolysis through hyperactivation of oncogenic KRAS.

Wang D, Bi Y, Hu L, Luo Y, Ji J, Mao AZ, Logsdon CD, Li E, Abbruzzese JL, Li Z, Yang VW, Lu W.

Cell Commun Signal. 2019 Feb 28;17(1):19. doi: 10.1186/s12964-019-0333-7.

5.

Transgenic expression of cyclooxygenase-2 in pancreatic acinar cells induces chronic pancreatitis.

Huang H, Chen J, Peng L, Yao Y, Deng D, Zhang Y, Liu Y, Wang H, Li Z, Bi Y, Haddock AN, Zhan X, Lu W, Logsdon CD, Ji B.

Am J Physiol Gastrointest Liver Physiol. 2019 Jan 1;316(1):G179-G186. doi: 10.1152/ajpgi.00096.2018. Epub 2018 Nov 15.

PMID:
30431318
6.

Suppression of stromal-derived Dickkopf-3 (DKK3) inhibits tumor progression and prolongs survival in pancreatic ductal adenocarcinoma.

Zhou L, Husted H, Moore T, Lu M, Deng D, Liu Y, Ramachandran V, Arumugam T, Niehrs C, Wang H, Chiao P, Ling J, Curran MA, Maitra A, Hung MC, Lee JE, Logsdon CD, Hwang RF.

Sci Transl Med. 2018 Oct 24;10(464). pii: eaat3487. doi: 10.1126/scitranslmed.aat3487.

7.

Galectin-3 Mediates Tumor Cell-Stroma Interactions by Activating Pancreatic Stellate Cells to Produce Cytokines via Integrin Signaling.

Zhao W, Ajani JA, Sushovan G, Ochi N, Hwang R, Hafley M, Johnson RL, Bresalier RS, Logsdon CD, Zhang Z, Song S.

Gastroenterology. 2018 Apr;154(5):1524-1537.e6. doi: 10.1053/j.gastro.2017.12.014. Epub 2017 Dec 21.

PMID:
29274868
8.

The immune system in cancer metastasis: friend or foe?

Janssen LME, Ramsay EE, Logsdon CD, Overwijk WW.

J Immunother Cancer. 2017 Oct 17;5(1):79. doi: 10.1186/s40425-017-0283-9. Review.

9.

RAGE maintains high levels of NFκB and oncogenic Kras activity in pancreatic cancer.

Azizan N, Suter MA, Liu Y, Logsdon CD.

Biochem Biophys Res Commun. 2017 Nov 4;493(1):592-597. doi: 10.1016/j.bbrc.2017.08.147. Epub 2017 Sep 1.

PMID:
28867179
10.

Lipocalin-2 Promotes Pancreatic Ductal Adenocarcinoma by Regulating Inflammation in the Tumor Microenvironment.

Gomez-Chou SB, Swidnicka-Siergiejko AK, Badi N, Chavez-Tomar M, Lesinski GB, Bekaii-Saab T, Farren MR, Mace TA, Schmidt C, Liu Y, Deng D, Hwang RF, Zhou L, Moore T, Chatterjee D, Wang H, Leng X, Arlinghaus RB, Logsdon CD, Cruz-Monserrate Z.

Cancer Res. 2017 May 15;77(10):2647-2660. doi: 10.1158/0008-5472.CAN-16-1986. Epub 2017 Mar 1.

11.

Chronic inflammation initiates multiple forms of K-Ras-independent mouse pancreatic cancer in the absence of TP53.

Swidnicka-Siergiejko AK, Gomez-Chou SB, Cruz-Monserrate Z, Deng D, Liu Y, Huang H, Ji B, Azizian N, Daniluk J, Lu W, Wang H, Maitra A, Logsdon CD.

Oncogene. 2017 Jun 1;36(22):3149-3158. doi: 10.1038/onc.2016.461. Epub 2016 Dec 19.

12.

The MET Receptor Tyrosine Kinase Confers Repair of Murine Pancreatic Acinar Cells following Acute and Chronic Injury.

Gaziova I, Jackson D, Boor PJ, Carter D, Cruz-Monserrate Z, Elferink CJ, Joshi AD, Kaphalia B, Logsdon CD, Pereira de Castro K, Soong L, Tao X, Qiu S, Elferink LA.

PLoS One. 2016 Oct 31;11(10):e0165485. doi: 10.1371/journal.pone.0165485. eCollection 2016.

13.

TM4SF1 Regulates Pancreatic Cancer Migration and Invasion In Vitro and In Vivo.

Cao J, Yang JC, Ramachandran V, Arumugam T, Deng DF, Li ZS, Xu LM, Logsdon CD.

Cell Physiol Biochem. 2016;39(2):740-50. doi: 10.1159/000445664. Epub 2016 Jul 27.

14.

Acinar Ductal Metaplasia: Yap Fills a Gap.

Means AL, Logsdon CD.

Gastroenterology. 2016 Sep;151(3):393-5. doi: 10.1053/j.gastro.2016.07.022. Epub 2016 Jul 25. No abstract available.

PMID:
27456389
15.

The Significance of Ras Activity in Pancreatic Cancer Initiation.

Logsdon CD, Lu W.

Int J Biol Sci. 2016 Jan 28;12(3):338-46. doi: 10.7150/ijbs.15020. eCollection 2016. Review.

16.

TM4SF1 Promotes Gemcitabine Resistance of Pancreatic Cancer In Vitro and In Vivo.

Cao J, Yang J, Ramachandran V, Arumugam T, Deng D, Li Z, Xu L, Logsdon CD.

PLoS One. 2015 Dec 28;10(12):e0144969. doi: 10.1371/journal.pone.0144969. eCollection 2015.

17.

Ductal activation of oncogenic KRAS alone induces sarcomatoid phenotype.

Fu Y, Cruz-Monserrate Z, Helen Lin H, Chung Y, Ji B, Lin SM, Vonderfecht S, Logsdon CD, Li CF, Ann DK.

Sci Rep. 2015 Aug 20;5:13347. doi: 10.1038/srep13347.

18.

Animal Models of Gastrointestinal and Liver Diseases. The difficulty of animal modeling of pancreatic cancer for preclinical evaluation of therapeutics.

Logsdon CD, Arumugam T, Ramachandran V.

Am J Physiol Gastrointest Liver Physiol. 2015 Sep 1;309(5):G283-91. doi: 10.1152/ajpgi.00169.2015. Epub 2015 Jul 9. Review.

19.

New Blocking Antibodies against Novel AGR2-C4.4A Pathway Reduce Growth and Metastasis of Pancreatic Tumors and Increase Survival in Mice.

Arumugam T, Deng D, Bover L, Wang H, Logsdon CD, Ramachandran V.

Mol Cancer Ther. 2015 Apr;14(4):941-51. doi: 10.1158/1535-7163.MCT-14-0470. Epub 2015 Feb 2.

20.

Preliminary evaluation of 1'-[(18)F]fluoroethyl-β-D-lactose ([(18)F]FEL) for detection of pancreatic cancer in nude mouse orthotopic xenografts.

Arumugam T, Paolillo V, Young D, Wen X, Logsdon CD, De Palatis L, Alauddin MM.

Nucl Med Biol. 2014 Nov-Dec;41(10):833-40. doi: 10.1016/j.nucmedbio.2014.08.001. Epub 2014 Aug 8.

21.

Convergence of nanotechnology and cancer prevention: are we there yet?

Menter DG, Patterson SL, Logsdon CD, Kopetz S, Sood AK, Hawk ET.

Cancer Prev Res (Phila). 2014 Oct;7(10):973-92. doi: 10.1158/1940-6207.CAPR-14-0079. Epub 2014 Jul 24. Review.

22.

Cell surface lactate receptor GPR81 is crucial for cancer cell survival.

Roland CL, Arumugam T, Deng D, Liu SH, Philip B, Gomez S, Burns WR, Ramachandran V, Wang H, Cruz-Monserrate Z, Logsdon CD.

Cancer Res. 2014 Sep 15;74(18):5301-10. doi: 10.1158/0008-5472.CAN-14-0319. Epub 2014 Jun 13.

23.

Targeting pancreatic ductal adenocarcinoma acidic microenvironment.

Cruz-Monserrate Z, Roland CL, Deng D, Arumugam T, Moshnikova A, Andreev OA, Reshetnyak YK, Logsdon CD.

Sci Rep. 2014 Mar 19;4:4410. doi: 10.1038/srep04410.

24.

Dietary energy balance modulation of Kras- and Ink4a/Arf+/--driven pancreatic cancer: the role of insulin-like growth factor-I.

Lashinger LM, Harrison LM, Rasmussen AJ, Logsdon CD, Fischer SM, McArthur MJ, Hursting SD.

Cancer Prev Res (Phila). 2013 Oct;6(10):1046-55. doi: 10.1158/1940-6207.CAPR-13-0185. Epub 2013 Aug 26.

25.

A high-fat diet activates oncogenic Kras and COX2 to induce development of pancreatic ductal adenocarcinoma in mice.

Philip B, Roland CL, Daniluk J, Liu Y, Chatterjee D, Gomez SB, Ji B, Huang H, Wang H, Fleming JB, Logsdon CD, Cruz-Monserrate Z.

Gastroenterology. 2013 Dec;145(6):1449-58. doi: 10.1053/j.gastro.2013.08.018. Epub 2013 Aug 16.

26.

A novel epigenetic CREB-miR-373 axis mediates ZIP4-induced pancreatic cancer growth.

Zhang Y, Yang J, Cui X, Chen Y, Zhu VF, Hagan JP, Wang H, Yu X, Hodges SE, Fang J, Chiao PJ, Logsdon CD, Fisher WE, Brunicardi FC, Chen C, Yao Q, Fernandez-Zapico ME, Li M.

EMBO Mol Med. 2013 Sep;5(9):1322-34. doi: 10.1002/emmm.201302507. Epub 2013 Jul 16.

27.

Dynamic mast cell-stromal cell interactions promote growth of pancreatic cancer.

Ma Y, Hwang RF, Logsdon CD, Ullrich SE.

Cancer Res. 2013 Jul 1;73(13):3927-37. doi: 10.1158/0008-5472.CAN-12-4479. Epub 2013 Apr 30.

28.

Roles for KRAS in pancreatic tumor development and progression.

di Magliano MP, Logsdon CD.

Gastroenterology. 2013 Jun;144(6):1220-9. doi: 10.1053/j.gastro.2013.01.071. Review.

29.

Plectin-1 Targeted AAV Vector for the Molecular Imaging of Pancreatic Cancer.

Konkalmatt PR, Deng D, Thomas S, Wu MT, Logsdon CD, French BA, Kelly KA.

Front Oncol. 2013 Apr 18;3:84. doi: 10.3389/fonc.2013.00084. eCollection 2013.

30.

The role of protein synthesis and digestive enzymes in acinar cell injury.

Logsdon CD, Ji B.

Nat Rev Gastroenterol Hepatol. 2013 Jun;10(6):362-70. doi: 10.1038/nrgastro.2013.36. Epub 2013 Mar 19. Review.

31.

Pancreatic cancer-associated Cathepsin E as a drug activator.

Abd-Elgaliel WR, Cruz-Monserrate Z, Wang H, Logsdon CD, Tung CH.

J Control Release. 2013 May 10;167(3):221-7. doi: 10.1016/j.jconrel.2013.02.007. Epub 2013 Feb 26.

32.

Oncogenic K-Ras requires activation for enhanced activity.

Huang H, Daniluk J, Liu Y, Chu J, Li Z, Ji B, Logsdon CD.

Oncogene. 2014 Jan 23;33(4):532-5. doi: 10.1038/onc.2012.619. Epub 2013 Jan 21.

33.

Designing and developing S100P inhibitor 5-methyl cromolyn for pancreatic cancer therapy.

Arumugam T, Ramachandran V, Sun D, Peng Z, Pal A, Maxwell DS, Bornmann WG, Logsdon CD.

Mol Cancer Ther. 2013 May;12(5):654-62. doi: 10.1158/1535-7163.MCT-12-0771. Epub 2013 Jan 9.

34.

Study human pancreatic cancer in mice: how close are they?

Zhang Y, Chen L, Yang J, Fleming JB, Chiao PJ, Logsdon CD, Li M.

Biochim Biophys Acta. 2013 Jan;1835(1):110-8. doi: 10.1016/j.bbcan.2012.11.001. Epub 2012 Nov 9. Review.

35.

Prostaglandin E2 regulates pancreatic stellate cell activity via the EP4 receptor.

Charo C, Holla V, Arumugam T, Hwang R, Yang P, Dubois RN, Menter DG, Logsdon CD, Ramachandran V.

Pancreas. 2013 Apr;42(3):467-74. doi: 10.1097/MPA.0b013e318264d0f8.

36.

Activation of nuclear factor-κB in acinar cells increases the severity of pancreatitis in mice.

Huang H, Liu Y, Daniluk J, Gaiser S, Chu J, Wang H, Li ZS, Logsdon CD, Ji B.

Gastroenterology. 2013 Jan;144(1):202-10. doi: 10.1053/j.gastro.2012.09.059. Epub 2012 Oct 3.

37.

Adrenomedullin is up-regulated in patients with pancreatic cancer and causes insulin resistance in β cells and mice.

Aggarwal G, Ramachandran V, Javeed N, Arumugam T, Dutta S, Klee GG, Klee EW, Smyrk TC, Bamlet W, Han JJ, Rumie Vittar NB, de Andrade M, Mukhopadhyay D, Petersen GM, Fernandez-Zapico ME, Logsdon CD, Chari ST.

Gastroenterology. 2012 Dec;143(6):1510-1517.e1. doi: 10.1053/j.gastro.2012.08.044. Epub 2012 Sep 6.

38.

Inhibition of the hedgehog pathway targets the tumor-associated stroma in pancreatic cancer.

Hwang RF, Moore TT, Hattersley MM, Scarpitti M, Yang B, Devereaux E, Ramachandran V, Arumugam T, Ji B, Logsdon CD, Brown JL, Godin R.

Mol Cancer Res. 2012 Sep;10(9):1147-57. Epub 2012 Aug 2.

39.

Met receptor tyrosine kinase signaling induces secretion of the angiogenic chemokine interleukin-8/CXCL8 in pancreatic cancer.

Hill KS, Gaziova I, Harrigal L, Guerra YA, Qiu S, Sastry SK, Arumugam T, Logsdon CD, Elferink LA.

PLoS One. 2012;7(7):e40420. doi: 10.1371/journal.pone.0040420. Epub 2012 Jul 17.

40.

S100P-derived RAGE antagonistic peptide reduces tumor growth and metastasis.

Arumugam T, Ramachandran V, Gomez SB, Schmidt AM, Logsdon CD.

Clin Cancer Res. 2012 Aug 15;18(16):4356-64. doi: 10.1158/1078-0432.CCR-12-0221. Epub 2012 Jun 20.

41.

An NF-κB pathway-mediated positive feedback loop amplifies Ras activity to pathological levels in mice.

Daniluk J, Liu Y, Deng D, Chu J, Huang H, Gaiser S, Cruz-Monserrate Z, Wang H, Ji B, Logsdon CD.

J Clin Invest. 2012 Apr;122(4):1519-28. doi: 10.1172/JCI59743. Epub 2012 Mar 12.

42.

A novel FoxM1-caveolin signaling pathway promotes pancreatic cancer invasion and metastasis.

Huang C, Qiu Z, Wang L, Peng Z, Jia Z, Logsdon CD, Le X, Wei D, Huang S, Xie K.

Cancer Res. 2012 Feb 1;72(3):655-65. doi: 10.1158/0008-5472.CAN-11-3102. Epub 2011 Dec 22.

43.

StellaTUM: current consensus and discussion on pancreatic stellate cell research.

Erkan M, Adler G, Apte MV, Bachem MG, Buchholz M, Detlefsen S, Esposito I, Friess H, Gress TM, Habisch HJ, Hwang RF, Jaster R, Kleeff J, Klöppel G, Kordes C, Logsdon CD, Masamune A, Michalski CW, Oh J, Phillips PA, Pinzani M, Reiser-Erkan C, Tsukamoto H, Wilson J.

Gut. 2012 Feb;61(2):172-8. doi: 10.1136/gutjnl-2011-301220. Epub 2011 Nov 24. No abstract available.

44.

Detection of pancreatic cancer tumours and precursor lesions by cathepsin E activity in mouse models.

Cruz-Monserrate Z, Abd-Elgaliel WR, Grote T, Deng D, Ji B, Arumugam T, Wang H, Tung CH, Logsdon CD.

Gut. 2012 Sep;61(9):1315-22. doi: 10.1136/gutjnl-2011-300544. Epub 2011 Nov 7.

45.

Digesting new information about the role of trypsin in pancreatitis.

Ji B, Logsdon CD.

Gastroenterology. 2011 Dec;141(6):1972-5. doi: 10.1053/j.gastro.2011.10.021. Epub 2011 Oct 25. No abstract available.

46.

Mast cells in tumor microenvironment promotes the in vivo growth of pancreatic ductal adenocarcinoma.

Chang DZ, Ma Y, Ji B, Wang H, Deng D, Liu Y, Abbruzzese JL, Liu YJ, Logsdon CD, Hwu P.

Clin Cancer Res. 2011 Nov 15;17(22):7015-23. doi: 10.1158/1078-0432.CCR-11-0607. Epub 2011 Oct 5.

47.

Molecular imaging of Cathepsin E-positive tumors in mice using a novel protease-activatable fluorescent probe.

Abd-Elgaliel WR, Cruz-Monserrate Z, Logsdon CD, Tung CH.

Mol Biosyst. 2011 Dec;7(12):3207-3213. doi: 10.1039/c1mb05215b. Epub 2011 Sep 20.

48.

Duct cells contribute to regeneration of endocrine and acinar cells following pancreatic damage in adult mice.

Criscimanna A, Speicher JA, Houshmand G, Shiota C, Prasadan K, Ji B, Logsdon CD, Gittes GK, Esni F.

Gastroenterology. 2011 Oct;141(4):1451-62, 1462.e1-6. doi: 10.1053/j.gastro.2011.07.003. Epub 2011 Jul 18.

49.

Trefoil factor 1 stimulates both pancreatic cancer and stellate cells and increases metastasis.

Arumugam T, Brandt W, Ramachandran V, Moore TT, Wang H, May FE, Westley BR, Hwang RF, Logsdon CD.

Pancreas. 2011 Aug;40(6):815-22. doi: 10.1097/MPA.0b013e31821f6927.

50.

Intracellular activation of trypsinogen in transgenic mice induces acute but not chronic pancreatitis.

Gaiser S, Daniluk J, Liu Y, Tsou L, Chu J, Lee W, Longnecker DS, Logsdon CD, Ji B.

Gut. 2011 Oct;60(10):1379-88. doi: 10.1136/gut.2010.226175. Epub 2011 Apr 6.

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