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Items: 1 to 50 of 143

1.

DeepSOFA: A Continuous Acuity Score for Critically Ill Patients using Clinically Interpretable Deep Learning.

Shickel B, Loftus TJ, Adhikari L, Ozrazgat-Baslanti T, Bihorac A, Rashidi P.

Sci Rep. 2019 Feb 12;9(1):1879. doi: 10.1038/s41598-019-38491-0.

2.

Cardiac Pseudoaneurysm Following Non-Operative Management After Penetrating Thoracoabdominal Trauma and Pericardial Window.

Jacobs C, Loftus TJ, Manning EW 3rd, Moore FA, Brakenridge SC.

J Trauma Acute Care Surg. 2019 Jan 8. doi: 10.1097/TA.0000000000002189. [Epub ahead of print] No abstract available.

PMID:
30629012
3.

Modulation of double-stranded RNA pattern recognition receptor signaling in ovarian cancer cells promotes inflammatory queues.

Muccioli M, Nandigam H, Loftus T, Singh M, Venkatesh A, Wright J, Pate M, McCall K, Benencia F.

Oncotarget. 2018 Nov 30;9(94):36666-36683. doi: 10.18632/oncotarget.26378. eCollection 2018 Nov 30.

4.

The impact of standardized protocol implementation for surgical damage control and temporary abdominal closure after emergent laparotomy.

Loftus TJ, Efron PA, Bala TM, Rosenthal MD, Croft CA, Walters MS, Smith RS, Moore FA, Mohr AM, Brakenridge SC.

J Trauma Acute Care Surg. 2018 Dec 18. doi: 10.1097/TA.0000000000002170. [Epub ahead of print]

PMID:
30562327
5.

Occult bowel injury after blunt abdominal trauma.

Loftus TJ, Morrow ML, Lottenberg L, Rosenthal MD, Croft CA, Smith RS, Moore FA, Brakenridge SC, Borrego R, Efron PA, Mohr AM.

Am J Surg. 2018 Nov 28. pii: S0002-9610(18)31253-4. doi: 10.1016/j.amjsurg.2018.11.018. [Epub ahead of print]

PMID:
30509454
6.

Persistent inflammation and anemia among critically ill septic patients.

Loftus TJ, Mira JC, Stortz JA, Ozrazgat-Baslanti T, Ghita GL, Wang Z, Brumback BA, Ungaro RF, Bihorac A, Leeuwenburgh C, Moore FA, Moldawer LL, Brakenridge SC, Efron PA, Mohr AM.

J Trauma Acute Care Surg. 2019 Feb;86(2):260-267. doi: 10.1097/TA.0000000000002147.

PMID:
30489504
7.

Pathologic stage dictates survival after neoadjuvant radiation for rectal cancer.

Delitto D, Loftus TJ, Iqbal A.

Oncotarget. 2018 Oct 26;9(84):35474-35475. doi: 10.18632/oncotarget.26262. eCollection 2018 Oct 26. No abstract available.

8.

Angiographic embolization followed by piecemeal resection of giant posterior mediastinal schwannoma: Case report and concise review.

Loftus TJ, Pipkin M, Machuca T, Oduntan O.

Int J Surg Case Rep. 2018;53:250-253. doi: 10.1016/j.ijscr.2018.10.055. Epub 2018 Oct 29.

9.

The Impact of Prior Laparotomy and Intra-abdominal Adhesions on Bowel and Mesenteric Injury Following Blunt Abdominal Trauma.

Loftus TJ, Morrow ML, Lottenberg L, Rosenthal MD, Croft CA, Smith RS, Moore FA, Brakenridge SC, Borrego R, Efron PA, Mohr AM.

World J Surg. 2019 Feb;43(2):457-465. doi: 10.1007/s00268-018-4792-6.

PMID:
30225563
10.

Packed red blood cell donor age affects overall survival in transfused patients undergoing hepatectomy for non-hepatocellular malignancy.

Loftus TJ, Lopez AN, Jenkins TK, Downey EM, Sikora JR, Pelletier JPR, Zendejas IR, Sarosi GA, Thomas RM.

Am J Surg. 2019 Jan;217(1):71-77. doi: 10.1016/j.amjsurg.2018.08.011. Epub 2018 Aug 27.

PMID:
30172359
11.

The effects of beta blockade and clonidine on persistent injury-associated anemia.

Loftus TJ, Rosenthal MD, Croft CA, Smith RS, Moore FA, Brakenridge SC, Efron PA, Mohr AM.

J Surg Res. 2018 Oct;230:175-180. doi: 10.1016/j.jss.2018.06.001. Epub 2018 Jun 28.

PMID:
29960715
12.

Anemia and blood transfusion in elderly trauma patients.

Loftus TJ, Brakenridge SC, Murphy TW, Nguyen LL, Moore FA, Efron PA, Mohr AM.

J Surg Res. 2018 Sep;229:288-293. doi: 10.1016/j.jss.2018.04.021.

PMID:
29937004
13.

Machine learning: a useful radiological adjunct in determination of a newly diagnosed glioma's grade and IDH status.

De Looze C, Beausang A, Cryan J, Loftus T, Buckley PG, Farrell M, Looby S, Reilly R, Brett F, Kearney H.

J Neurooncol. 2018 Sep;139(2):491-499. doi: 10.1007/s11060-018-2895-4. Epub 2018 May 16.

PMID:
29770897
14.

The Postinjury Inflammatory State and the Bone Marrow Response to Anemia.

Loftus TJ, Mira JC, Miller ES, Kannan KB, Plazas JM, Delitto D, Stortz JA, Hagen JE, Parvataneni HK, Sadasivan KK, Brakenridge SC, Moore FA, Moldawer LL, Efron PA, Mohr AM.

Am J Respir Crit Care Med. 2018 Sep 1;198(5):629-638. doi: 10.1164/rccm.201712-2536OC.

PMID:
29768025
15.

Innate Immunity in the Persistent Inflammation, Immunosuppression, and Catabolism Syndrome and Its Implications for Therapy.

Horiguchi H, Loftus TJ, Hawkins RB, Raymond SL, Stortz JA, Hollen MK, Weiss BP, Miller ES, Bihorac A, Larson SD, Mohr AM, Brakenridge SC, Tsujimoto H, Ueno H, Moore FA, Moldawer LL, Efron PA; Sepsis and Critical Illness Research Center Investigators.

Front Immunol. 2018 Apr 4;9:595. doi: 10.3389/fimmu.2018.00595. eCollection 2018. Review.

16.

Patient-specific and hospital resource-specific considerations in operative versus nonoperative management of acute appendicitis.

Loftus TJ, Jordan JR.

J Surg Res. 2018 Apr 2. pii: S0022-4804(18)30172-0. doi: 10.1016/j.jss.2018.03.005. [Epub ahead of print] No abstract available.

PMID:
29622400
17.

Mouse Injury Model of Polytrauma and Shock.

Mira JC, Nacionales DC, Loftus TJ, Ungaro R, Mathias B, Mohr AM, Moldawer LL, Efron PA.

Methods Mol Biol. 2018;1717:1-15. doi: 10.1007/978-1-4939-7526-6_1. Review.

18.

Persistent injury-associated anemia and aging: Novel insights.

Loftus TJ, Kannan KB, Carter CS, Plazas JM, Mira JC, Brakenridge SC, Leeuwenburgh C, Efron PA, Mohr AM.

J Trauma Acute Care Surg. 2018 Mar;84(3):490-496. doi: 10.1097/TA.0000000000001766.

PMID:
29466280
19.

A protocol for non-operative management of uncomplicated appendicitis.

Loftus TJ, Dessaigne CG, Croft CA, Smith RS, Efron PA, Moore FA, Brakenridge SC, Mohr AM, Jordan JR.

J Trauma Acute Care Surg. 2018 Feb;84(2):358-364. doi: 10.1097/TA.0000000000001709.

20.

Effect of Time to Operation on Value of Care in Acute Care Surgery.

Loftus TJ, Rosenthal MD, Croft CA, Stephen Smith R, Efron PA, Moore FA, Mohr AM, Brakenridge SC.

World J Surg. 2018 Aug;42(8):2356-2363. doi: 10.1007/s00268-018-4476-2.

PMID:
29352339
21.

Regulation of inflammatory factors by double-stranded RNA receptors in breast cancer cells.

Venkatesh A, Nandigam H, Muccioli M, Singh M, Loftus T, Lewis D, Pate M, Benencia F.

Immunobiology. 2018 Jun - Jul;223(6-7):466-476. doi: 10.1016/j.imbio.2017.11.005. Epub 2017 Nov 22.

PMID:
29331323
22.

Persistent injury-associated anemia in aged rats.

Loftus TJ, Kannan KB, Carter CS, Plazas JM, Mira JC, Brakenridge SC, Leeuwenburgh C, Efron PA, Mohr AM.

Exp Gerontol. 2018 Mar;103:63-68. doi: 10.1016/j.exger.2018.01.001. Epub 2018 Jan 4.

PMID:
29307734
23.

Temporal stability of MGMT promoter methylation in glioblastoma patients undergoing STUPP protocol.

O'Regan CJ, Kearney H, Beausang A, Farrell MA, Brett FM, Cryan JB, Loftus TE, Buckley PG.

J Neurooncol. 2018 Apr;137(2):233-240. doi: 10.1007/s11060-017-2722-3. Epub 2017 Dec 20.

PMID:
29264834
24.

Benchmarking clinical outcomes and the immunocatabolic phenotype of chronic critical illness after sepsis in surgical intensive care unit patients.

Stortz JA, Mira JC, Raymond SL, Loftus TJ, Ozrazgat-Baslanti T, Wang Z, Ghita GL, Leeuwenburgh C, Segal MS, Bihorac A, Brumback BA, Mohr AM, Efron PA, Moldawer LL, Moore FA, Brakenridge SC.

J Trauma Acute Care Surg. 2018 Feb;84(2):342-349. doi: 10.1097/TA.0000000000001758.

25.

Prognostic Value of Clinical vs Pathologic Stage in Rectal Cancer Patients Receiving Neoadjuvant Therapy.

Delitto D, George TJ Jr, Loftus TJ, Qiu P, Chang GJ, Allegra CJ, Hall WA, Hughes SJ, Tan SA, Shaw CM, Iqbal A.

J Natl Cancer Inst. 2018 May 1;110(5):460-466. doi: 10.1093/jnci/djx228.

26.

Successful nonoperative management of uncomplicated appendicitis: predictors and outcomes.

Loftus TJ, Brakenridge SC, Croft CA, Stephen Smith R, Efron PA, Moore FA, Mohr AM, Jordan JR.

J Surg Res. 2018 Feb;222:212-218.e2. doi: 10.1016/j.jss.2017.10.006. Epub 2017 Nov 13.

27.

Hypertonic saline resuscitation after emergent laparotomy and temporary abdominal closure.

Loftus TJ, Efron PA, Bala TM, Rosenthal MD, Croft CA, Smith RS, Moore FA, Mohr AM, Brakenridge SC.

J Trauma Acute Care Surg. 2018 Feb;84(2):350-357. doi: 10.1097/TA.0000000000001730.

28.

Response to Er and Tez: the use of artificial neural networks in medical prognostication.

Loftus TJ, Jordan JR.

J Surg Res. 2018 Feb;222:226. doi: 10.1016/j.jss.2017.10.005. Epub 2017 Oct 27. No abstract available.

29.

Dysregulated myelopoiesis and hematopoietic function following acute physiologic insult.

Loftus TJ, Mohr AM, Moldawer LL.

Curr Opin Hematol. 2018 Jan;25(1):37-43. doi: 10.1097/MOH.0000000000000395. Review.

30.

ICU-Acquired Weakness, Chronic Critical Illness, and the Persistent Inflammation-Immunosuppression and Catabolism Syndrome.

Loftus TJ, Moore FA, Moldawer LL.

Crit Care Med. 2017 Nov;45(11):e1184. doi: 10.1097/CCM.0000000000002576. No abstract available.

31.

Evidence for Persistent Immune Suppression in Patients Who Develop Chronic Critical Illness After Sepsis.

Stortz JA, Murphy TJ, Raymond SL, Mira JC, Ungaro R, Dirain ML, Nacionales DC, Loftus TJ, Wang Z, Ozrazgat-Baslanti T, Ghita GL, Brumback BA, Mohr AM, Bihorac A, Efron PA, Moldawer LL, Moore FA, Brakenridge SC.

Shock. 2018 Mar;49(3):249-258. doi: 10.1097/SHK.0000000000000981.

PMID:
28885387
32.

EBV driven natural killer cell disease of the central nervous system presenting as subacute cognitive decline.

Brett FM, Flavin R, Chen D, Loftus T, Looby S, McCarthy A, de Gascun C, Jaffe ES, Nor N, Javadpour M, McCabe D.

Hum Pathol (N Y). 2017 Nov;10:64-68. doi: 10.1016/j.ehpc.2017.06.007.

33.

Characterization of hypoalbuminemia following temporary abdominal closure.

Loftus TJ, Jordan JR, Croft CA, Smith RS, Efron PA, Moore FA, Mohr AM, Brakenridge SC.

J Trauma Acute Care Surg. 2017 Oct;83(4):650-656. doi: 10.1097/TA.0000000000001553.

34.

The Epidemiology of Chronic Critical Illness After Severe Traumatic Injury at Two Level-One Trauma Centers.

Mira JC, Cuschieri J, Ozrazgat-Baslanti T, Wang Z, Ghita GL, Loftus TJ, Stortz JA, Raymond SL, Lanz JD, Hennessy LV, Brumback B, Efron PA, Baker HV, Moore FA, Maier RV, Moldawer LL, Brakenridge SC.

Crit Care Med. 2017 Dec;45(12):1989-1996. doi: 10.1097/CCM.0000000000002697.

35.

Brain biopsies requiring Creutzfeldt-Jakob disease precautions in the Republic of Ireland 2005-2016.

Brett FM, Looby S, Chalissery A, Chen D, Heaney C, Heffernan J, Cunningham F, Howley R, Loftus T, Kearney H, Farrell MA.

Ir J Med Sci. 2018 May;187(2):515-520. doi: 10.1007/s11845-017-1673-1. Epub 2017 Aug 12.

PMID:
28803271
36.

Sepsis and Critical Illness Research Center investigators: protocols and standard operating procedures for a prospective cohort study of sepsis in critically ill surgical patients.

Loftus TJ, Mira JC, Ozrazgat-Baslanti T, Ghita GL, Wang Z, Stortz JA, Brumback BA, Bihorac A, Segal MS, Anton SD, Leeuwenburgh C, Mohr AM, Efron PA, Moldawer LL, Moore FA, Brakenridge SC.

BMJ Open. 2017 Aug 1;7(7):e015136. doi: 10.1136/bmjopen-2016-015136.

37.

Intravascular large B-cell lymphoma presenting clinically as rapidly progressive dementia.

Brett FM, Chen D, Loftus T, Langan Y, Looby S, Hutchinson S.

Ir J Med Sci. 2018 May;187(2):319-322. doi: 10.1007/s11845-017-1653-5. Epub 2017 Jul 19. Review.

PMID:
28726030
38.

The effects of red cell transfusion donor age on nosocomial infection among trauma patients.

Loftus TJ, Thomas RM, Murphy TW, Nguyen LL, Moore FA, Brakenridge SC, Efron PA, Mohr AM.

Am J Surg. 2017 Oct;214(4):672-676. doi: 10.1016/j.amjsurg.2017.07.004. Epub 2017 Jul 12.

39.

Clonidine restores vascular endothelial growth factor expression and improves tissue repair following severe trauma.

Loftus TJ, Thomson AJ, Kannan KB, Alamo IG, Millar JK, Plazas JM, Whitley EE, Efron PA, Mohr AM.

Am J Surg. 2017 Oct;214(4):610-615. doi: 10.1016/j.amjsurg.2017.06.019. Epub 2017 Jun 23.

40.

Persistent injury-associated anemia: the role of the bone marrow microenvironment.

Millar JK, Kannan KB, Loftus TJ, Alamo IG, Plazas J, Efron PA, Mohr AM.

J Surg Res. 2017 Jun 15;214:240-246. doi: 10.1016/j.jss.2017.03.018. Epub 2017 Mar 31.

41.

Neural network prediction of severe lower intestinal bleeding and the need for surgical intervention.

Loftus TJ, Brakenridge SC, Croft CA, Smith RS, Efron PA, Moore FA, Mohr AM, Jordan JR.

J Surg Res. 2017 May 15;212:42-47. doi: 10.1016/j.jss.2016.12.032. Epub 2016 Dec 30.

42.

A System-Wide Enhanced Recovery Program Focusing on Two Key Process Steps Reduces Complications and Readmissions in Patients Undergoing Bowel Surgery.

Loftus TJ, Stelton S, Efaw BW, Bloomstone J.

J Healthc Qual. 2017 May/Jun;39(3):129-135. doi: 10.1111/jhq.12068.

PMID:
28481841
43.

Effects of trauma, hemorrhagic shock, and chronic stress on lung vascular endothelial growth factor.

Loftus TJ, Thomson AJ, Kannan KB, Alamo IG, Ramos HN, Whitley EE, Efron PA, Mohr AM.

J Surg Res. 2017 Apr;210:15-21. doi: 10.1016/j.jss.2016.10.023. Epub 2016 Nov 2.

44.

Emergent laparotomy and temporary abdominal closure for the cirrhotic patient.

Loftus TJ, Jordan JR, Croft CA, Smith RS, Efron PA, Moore FA, Mohr AM, Brakenridge SC.

J Surg Res. 2017 Apr;210:108-114. doi: 10.1016/j.jss.2016.11.013. Epub 2016 Nov 11.

45.

Severe trauma and chronic stress activates extramedullary erythropoiesis.

Alamo IG, Kannan KB, Loftus TJ, Ramos H, Efron PA, Mohr AM.

J Trauma Acute Care Surg. 2017 Jul;83(1):144-150. doi: 10.1097/TA.0000000000001537.

46.

Computed tomography evidence of fluid in the hernia sac predicts surgical site infection following mesh repair of acutely incarcerated ventral and groin hernias.

Loftus TJ, Go KL, Jordan JR, Croft CA, Smith RS, Moore FA, Efron PA, Mohr AM, Brakenridge SC.

J Trauma Acute Care Surg. 2017 Jul;83(1):170-174. doi: 10.1097/TA.0000000000001503.

47.

Percutaneous cholecystostomy: prognostic factors and comparison to cholecystectomy.

Loftus TJ, Collins EM, Dessaigne CG, Himmler AN, Mohr AM, Thomas RM, Hobson CE, Sarosi GA Jr, Zingarelli WJ.

Surg Endosc. 2017 Nov;31(11):4568-4575. doi: 10.1007/s00464-017-5517-x. Epub 2017 Apr 13.

48.

CJD surveillance in the Republic of Ireland from 2005 to 2015: a suggested algorithm for referrals.

Loftus T, Chen D, Looby S, Chalissery A, Howley R, Heaney C, Heffernan J, Farrell M, Brett F.

Clin Neuropathol. 2017 Jul/Aug;36(4):188-194. doi: 10.5414/NP301016.

PMID:
28332471
49.

Early bronchoalveolar lavage for intubated trauma patients with TBI or chest trauma.

Loftus TJ, Lemon SJ, Nguyen LL, Voils SA, Brakenridge SC, Jordan JR, Croft CA, Smith RS, Moore FA, Efron PA, Mohr AM.

J Crit Care. 2017 Jun;39:78-82. doi: 10.1016/j.jcrc.2017.02.010. Epub 2017 Feb 12.

50.

Microbial recognition and danger signals in sepsis and trauma.

Raymond SL, Holden DC, Mira JC, Stortz JA, Loftus TJ, Mohr AM, Moldawer LL, Moore FA, Larson SD, Efron PA.

Biochim Biophys Acta Mol Basis Dis. 2017 Oct;1863(10 Pt B):2564-2573. doi: 10.1016/j.bbadis.2017.01.013. Epub 2017 Jan 20. Review.

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