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Items: 1 to 50 of 135

1.

The Impact of Prior Laparotomy and Intra-abdominal Adhesions on Bowel and Mesenteric Injury Following Blunt Abdominal Trauma.

Loftus TJ, Morrow ML, Lottenberg L, Rosenthal MD, Croft CA, Smith RS, Moore FA, Brakenridge SC, Borrego R, Efron PA, Mohr AM.

World J Surg. 2018 Sep 17. doi: 10.1007/s00268-018-4792-6. [Epub ahead of print]

PMID:
30225563
2.

Packed red blood cell donor age affects overall survival in transfused patients undergoing hepatectomy for non-hepatocellular malignancy.

Loftus TJ, Lopez AN, Jenkins TK, Downey EM, Sikora JR, Pelletier JPR, Zendejas IR, Sarosi GA, Thomas RM.

Am J Surg. 2018 Aug 27. pii: S0002-9610(18)30838-9. doi: 10.1016/j.amjsurg.2018.08.011. [Epub ahead of print]

PMID:
30172359
3.

The effects of beta blockade and clonidine on persistent injury-associated anemia.

Loftus TJ, Rosenthal MD, Croft CA, Smith RS, Moore FA, Brakenridge SC, Efron PA, Mohr AM.

J Surg Res. 2018 Oct;230:175-180. doi: 10.1016/j.jss.2018.06.001. Epub 2018 Jun 28.

PMID:
29960715
4.

Anemia and blood transfusion in elderly trauma patients.

Loftus TJ, Brakenridge SC, Murphy TW, Nguyen LL, Moore FA, Efron PA, Mohr AM.

J Surg Res. 2018 Sep;229:288-293. doi: 10.1016/j.jss.2018.04.021.

PMID:
29937004
5.

Machine learning: a useful radiological adjunct in determination of a newly diagnosed glioma's grade and IDH status.

De Looze C, Beausang A, Cryan J, Loftus T, Buckley PG, Farrell M, Looby S, Reilly R, Brett F, Kearney H.

J Neurooncol. 2018 May 16. doi: 10.1007/s11060-018-2895-4. [Epub ahead of print]

PMID:
29770897
6.

The Postinjury Inflammatory State and the Bone Marrow Response to Anemia.

Loftus TJ, Mira JC, Miller ES, Kannan KB, Plazas JM, Delitto D, Stortz JA, Hagen JE, Parvataneni HK, Sadasivan KK, Brakenridge SC, Moore FA, Moldawer LL, Efron PA, Mohr AM.

Am J Respir Crit Care Med. 2018 Sep 1;198(5):629-638. doi: 10.1164/rccm.201712-2536OC.

PMID:
29768025
7.

Innate Immunity in the Persistent Inflammation, Immunosuppression, and Catabolism Syndrome and Its Implications for Therapy.

Horiguchi H, Loftus TJ, Hawkins RB, Raymond SL, Stortz JA, Hollen MK, Weiss BP, Miller ES, Bihorac A, Larson SD, Mohr AM, Brakenridge SC, Tsujimoto H, Ueno H, Moore FA, Moldawer LL, Efron PA; Sepsis and Critical Illness Research Center Investigators.

Front Immunol. 2018 Apr 4;9:595. doi: 10.3389/fimmu.2018.00595. eCollection 2018. Review.

8.

Patient-specific and hospital resource-specific considerations in operative versus nonoperative management of acute appendicitis.

Loftus TJ, Jordan JR.

J Surg Res. 2018 Apr 2. pii: S0022-4804(18)30172-0. doi: 10.1016/j.jss.2018.03.005. [Epub ahead of print] No abstract available.

PMID:
29622400
9.

Mouse Injury Model of Polytrauma and Shock.

Mira JC, Nacionales DC, Loftus TJ, Ungaro R, Mathias B, Mohr AM, Moldawer LL, Efron PA.

Methods Mol Biol. 2018;1717:1-15. doi: 10.1007/978-1-4939-7526-6_1.

PMID:
29468579
10.

Persistent injury-associated anemia and aging: Novel insights.

Loftus TJ, Kannan KB, Carter CS, Plazas JM, Mira JC, Brakenridge SC, Leeuwenburgh C, Efron PA, Mohr AM.

J Trauma Acute Care Surg. 2018 Mar;84(3):490-496. doi: 10.1097/TA.0000000000001766.

PMID:
29466280
11.

A protocol for non-operative management of uncomplicated appendicitis.

Loftus TJ, Dessaigne CG, Croft CA, Smith RS, Efron PA, Moore FA, Brakenridge SC, Mohr AM, Jordan JR.

J Trauma Acute Care Surg. 2018 Feb;84(2):358-364. doi: 10.1097/TA.0000000000001709.

PMID:
29370051
12.

Effect of Time to Operation on Value of Care in Acute Care Surgery.

Loftus TJ, Rosenthal MD, Croft CA, Stephen Smith R, Efron PA, Moore FA, Mohr AM, Brakenridge SC.

World J Surg. 2018 Aug;42(8):2356-2363. doi: 10.1007/s00268-018-4476-2.

PMID:
29352339
13.

Regulation of inflammatory factors by double-stranded RNA receptors in breast cancer cells.

Venkatesh A, Nandigam H, Muccioli M, Singh M, Loftus T, Lewis D, Pate M, Benencia F.

Immunobiology. 2018 Jun - Jul;223(6-7):466-476. doi: 10.1016/j.imbio.2017.11.005. Epub 2017 Nov 22.

PMID:
29331323
14.

Persistent injury-associated anemia in aged rats.

Loftus TJ, Kannan KB, Carter CS, Plazas JM, Mira JC, Brakenridge SC, Leeuwenburgh C, Efron PA, Mohr AM.

Exp Gerontol. 2018 Mar;103:63-68. doi: 10.1016/j.exger.2018.01.001. Epub 2018 Jan 4.

PMID:
29307734
15.

Temporal stability of MGMT promoter methylation in glioblastoma patients undergoing STUPP protocol.

O'Regan CJ, Kearney H, Beausang A, Farrell MA, Brett FM, Cryan JB, Loftus TE, Buckley PG.

J Neurooncol. 2018 Apr;137(2):233-240. doi: 10.1007/s11060-017-2722-3. Epub 2017 Dec 20.

PMID:
29264834
16.

Benchmarking clinical outcomes and the immunocatabolic phenotype of chronic critical illness after sepsis in surgical intensive care unit patients.

Stortz JA, Mira JC, Raymond SL, Loftus TJ, Ozrazgat-Baslanti T, Wang Z, Ghita GL, Leeuwenburgh C, Segal MS, Bihorac A, Brumback BA, Mohr AM, Efron PA, Moldawer LL, Moore FA, Brakenridge SC.

J Trauma Acute Care Surg. 2018 Feb;84(2):342-349. doi: 10.1097/TA.0000000000001758.

PMID:
29251709
17.

Prognostic Value of Clinical vs Pathologic Stage in Rectal Cancer Patients Receiving Neoadjuvant Therapy.

Delitto D, George TJ Jr, Loftus TJ, Qiu P, Chang GJ, Allegra CJ, Hall WA, Hughes SJ, Tan SA, Shaw CM, Iqbal A.

J Natl Cancer Inst. 2018 May 1;110(5):460-466. doi: 10.1093/jnci/djx228.

PMID:
29165692
18.

Successful nonoperative management of uncomplicated appendicitis: predictors and outcomes.

Loftus TJ, Brakenridge SC, Croft CA, Stephen Smith R, Efron PA, Moore FA, Mohr AM, Jordan JR.

J Surg Res. 2018 Feb;222:212-218.e2. doi: 10.1016/j.jss.2017.10.006. Epub 2017 Nov 13.

PMID:
29146455
19.

Hypertonic saline resuscitation after emergent laparotomy and temporary abdominal closure.

Loftus TJ, Efron PA, Bala TM, Rosenthal MD, Croft CA, Smith RS, Moore FA, Mohr AM, Brakenridge SC.

J Trauma Acute Care Surg. 2018 Feb;84(2):350-357. doi: 10.1097/TA.0000000000001730.

PMID:
29140948
20.

Response to Er and Tez: the use of artificial neural networks in medical prognostication.

Loftus TJ, Jordan JR.

J Surg Res. 2018 Feb;222:226. doi: 10.1016/j.jss.2017.10.005. Epub 2017 Oct 27. No abstract available.

PMID:
29110965
21.

Dysregulated myelopoiesis and hematopoietic function following acute physiologic insult.

Loftus TJ, Mohr AM, Moldawer LL.

Curr Opin Hematol. 2018 Jan;25(1):37-43. doi: 10.1097/MOH.0000000000000395. Review.

PMID:
29035909
22.

ICU-Acquired Weakness, Chronic Critical Illness, and the Persistent Inflammation-Immunosuppression and Catabolism Syndrome.

Loftus TJ, Moore FA, Moldawer LL.

Crit Care Med. 2017 Nov;45(11):e1184. doi: 10.1097/CCM.0000000000002576. No abstract available.

PMID:
29028707
23.

Evidence for Persistent Immune Suppression in Patients Who Develop Chronic Critical Illness After Sepsis.

Stortz JA, Murphy TJ, Raymond SL, Mira JC, Ungaro R, Dirain ML, Nacionales DC, Loftus TJ, Wang Z, Ozrazgat-Baslanti T, Ghita GL, Brumback BA, Mohr AM, Bihorac A, Efron PA, Moldawer LL, Moore FA, Brakenridge SC.

Shock. 2018 Mar;49(3):249-258. doi: 10.1097/SHK.0000000000000981.

PMID:
28885387
24.

EBV driven natural killer cell disease of the central nervous system presenting as subacute cognitive decline.

Brett FM, Flavin R, Chen D, Loftus T, Looby S, McCarthy A, de Gascun C, Jaffe ES, Nor N, Javadpour M, McCabe D.

Hum Pathol (N Y). 2017 Nov;10:64-68. doi: 10.1016/j.ehpc.2017.06.007.

25.

Characterization of hypoalbuminemia following temporary abdominal closure.

Loftus TJ, Jordan JR, Croft CA, Smith RS, Efron PA, Moore FA, Mohr AM, Brakenridge SC.

J Trauma Acute Care Surg. 2017 Oct;83(4):650-656. doi: 10.1097/TA.0000000000001553.

PMID:
28837537
26.

The Epidemiology of Chronic Critical Illness After Severe Traumatic Injury at Two Level-One Trauma Centers.

Mira JC, Cuschieri J, Ozrazgat-Baslanti T, Wang Z, Ghita GL, Loftus TJ, Stortz JA, Raymond SL, Lanz JD, Hennessy LV, Brumback B, Efron PA, Baker HV, Moore FA, Maier RV, Moldawer LL, Brakenridge SC.

Crit Care Med. 2017 Dec;45(12):1989-1996. doi: 10.1097/CCM.0000000000002697.

PMID:
28837430
27.

Brain biopsies requiring Creutzfeldt-Jakob disease precautions in the Republic of Ireland 2005-2016.

Brett FM, Looby S, Chalissery A, Chen D, Heaney C, Heffernan J, Cunningham F, Howley R, Loftus T, Kearney H, Farrell MA.

Ir J Med Sci. 2018 May;187(2):515-520. doi: 10.1007/s11845-017-1673-1. Epub 2017 Aug 12.

PMID:
28803271
28.

Sepsis and Critical Illness Research Center investigators: protocols and standard operating procedures for a prospective cohort study of sepsis in critically ill surgical patients.

Loftus TJ, Mira JC, Ozrazgat-Baslanti T, Ghita GL, Wang Z, Stortz JA, Brumback BA, Bihorac A, Segal MS, Anton SD, Leeuwenburgh C, Mohr AM, Efron PA, Moldawer LL, Moore FA, Brakenridge SC.

BMJ Open. 2017 Aug 1;7(7):e015136. doi: 10.1136/bmjopen-2016-015136.

29.

Intravascular large B-cell lymphoma presenting clinically as rapidly progressive dementia.

Brett FM, Chen D, Loftus T, Langan Y, Looby S, Hutchinson S.

Ir J Med Sci. 2018 May;187(2):319-322. doi: 10.1007/s11845-017-1653-5. Epub 2017 Jul 19. Review.

PMID:
28726030
30.

The effects of red cell transfusion donor age on nosocomial infection among trauma patients.

Loftus TJ, Thomas RM, Murphy TW, Nguyen LL, Moore FA, Brakenridge SC, Efron PA, Mohr AM.

Am J Surg. 2017 Oct;214(4):672-676. doi: 10.1016/j.amjsurg.2017.07.004. Epub 2017 Jul 12.

PMID:
28720216
31.

Clonidine restores vascular endothelial growth factor expression and improves tissue repair following severe trauma.

Loftus TJ, Thomson AJ, Kannan KB, Alamo IG, Millar JK, Plazas JM, Whitley EE, Efron PA, Mohr AM.

Am J Surg. 2017 Oct;214(4):610-615. doi: 10.1016/j.amjsurg.2017.06.019. Epub 2017 Jun 23.

PMID:
28666582
32.

Persistent injury-associated anemia: the role of the bone marrow microenvironment.

Millar JK, Kannan KB, Loftus TJ, Alamo IG, Plazas J, Efron PA, Mohr AM.

J Surg Res. 2017 Jun 15;214:240-246. doi: 10.1016/j.jss.2017.03.018. Epub 2017 Mar 31.

33.

Neural network prediction of severe lower intestinal bleeding and the need for surgical intervention.

Loftus TJ, Brakenridge SC, Croft CA, Smith RS, Efron PA, Moore FA, Mohr AM, Jordan JR.

J Surg Res. 2017 May 15;212:42-47. doi: 10.1016/j.jss.2016.12.032. Epub 2016 Dec 30.

34.

A System-Wide Enhanced Recovery Program Focusing on Two Key Process Steps Reduces Complications and Readmissions in Patients Undergoing Bowel Surgery.

Loftus TJ, Stelton S, Efaw BW, Bloomstone J.

J Healthc Qual. 2017 May/Jun;39(3):129-135. doi: 10.1111/jhq.12068.

PMID:
28481841
35.

Effects of trauma, hemorrhagic shock, and chronic stress on lung vascular endothelial growth factor.

Loftus TJ, Thomson AJ, Kannan KB, Alamo IG, Ramos HN, Whitley EE, Efron PA, Mohr AM.

J Surg Res. 2017 Apr;210:15-21. doi: 10.1016/j.jss.2016.10.023. Epub 2016 Nov 2.

36.

Emergent laparotomy and temporary abdominal closure for the cirrhotic patient.

Loftus TJ, Jordan JR, Croft CA, Smith RS, Efron PA, Moore FA, Mohr AM, Brakenridge SC.

J Surg Res. 2017 Apr;210:108-114. doi: 10.1016/j.jss.2016.11.013. Epub 2016 Nov 11.

37.

Severe trauma and chronic stress activates extramedullary erythropoiesis.

Alamo IG, Kannan KB, Loftus TJ, Ramos H, Efron PA, Mohr AM.

J Trauma Acute Care Surg. 2017 Jul;83(1):144-150. doi: 10.1097/TA.0000000000001537.

38.

Computed tomography evidence of fluid in the hernia sac predicts surgical site infection following mesh repair of acutely incarcerated ventral and groin hernias.

Loftus TJ, Go KL, Jordan JR, Croft CA, Smith RS, Moore FA, Efron PA, Mohr AM, Brakenridge SC.

J Trauma Acute Care Surg. 2017 Jul;83(1):170-174. doi: 10.1097/TA.0000000000001503.

39.

Percutaneous cholecystostomy: prognostic factors and comparison to cholecystectomy.

Loftus TJ, Collins EM, Dessaigne CG, Himmler AN, Mohr AM, Thomas RM, Hobson CE, Sarosi GA Jr, Zingarelli WJ.

Surg Endosc. 2017 Nov;31(11):4568-4575. doi: 10.1007/s00464-017-5517-x. Epub 2017 Apr 13.

PMID:
28409378
40.

CJD surveillance in the Republic of Ireland from 2005 to 2015: a suggested algorithm for referrals.

Loftus T, Chen D, Looby S, Chalissery A, Howley R, Heaney C, Heffernan J, Farrell M, Brett F.

Clin Neuropathol. 2017 Jul/Aug;36(4):188-194. doi: 10.5414/NP301016.

PMID:
28332471
41.

Early bronchoalveolar lavage for intubated trauma patients with TBI or chest trauma.

Loftus TJ, Lemon SJ, Nguyen LL, Voils SA, Brakenridge SC, Jordan JR, Croft CA, Smith RS, Moore FA, Efron PA, Mohr AM.

J Crit Care. 2017 Jun;39:78-82. doi: 10.1016/j.jcrc.2017.02.010. Epub 2017 Feb 12.

42.

Microbial recognition and danger signals in sepsis and trauma.

Raymond SL, Holden DC, Mira JC, Stortz JA, Loftus TJ, Mohr AM, Moldawer LL, Moore FA, Larson SD, Efron PA.

Biochim Biophys Acta Mol Basis Dis. 2017 Oct;1863(10 Pt B):2564-2573. doi: 10.1016/j.bbadis.2017.01.013. Epub 2017 Jan 20. Review.

PMID:
28115287
43.

Daily propranolol administration reduces persistent injury-associated anemia after severe trauma and chronic stress.

Alamo IG, Kannan KB, Bible LE, Loftus TJ, Ramos H, Efron PA, Mohr AM.

J Trauma Acute Care Surg. 2017 Apr;82(4):714-721. doi: 10.1097/TA.0000000000001374.

44.

Predicting appendiceal tumors among patients with appendicitis.

Loftus TJ, Raymond SL, Sarosi GA Jr, Croft CA, Smith RS, Efron PA, Moore FA, Brakenridge SC, Mohr AM, Jordan JR.

J Trauma Acute Care Surg. 2017 Apr;82(4):771-775. doi: 10.1097/TA.0000000000001378.

45.

Antibiotics May be Safely Discontinued Within One Week of Percutaneous Cholecystostomy.

Loftus TJ, Brakenridge SC, Dessaigne CG, Sarosi GA Jr, Zingarelli WJ, Moore FA, Jordan JR, Croft CA, Smith RS, Efron PA, Mohr AM.

World J Surg. 2017 May;41(5):1239-1245. doi: 10.1007/s00268-016-3861-y.

46.

Acute Kidney Injury Following Exploratory Laparotomy and Temporary Abdominal Closure.

Loftus TJ, Bihorac A, Ozrazgat-Baslanti T, Jordan JR, Croft CA, Smith RS, Efron PA, Moore FA, Mohr AM, Brakenridge SC.

Shock. 2017 Jul;48(1):5-10. doi: 10.1097/SHK.0000000000000825.

47.

Routine surveillance cholangiography after percutaneous cholecystostomy delays drain removal and cholecystectomy.

Loftus TJ, Brakenridge SC, Moore FA, Dessaigne CG, Sarosi GA Jr, Zingarelli WJ, Jordan JR, Croft CA, Smith RS, Efron PA, Mohr AM.

J Trauma Acute Care Surg. 2017 Feb;82(2):351-355. doi: 10.1097/TA.0000000000001315.

48.

Temporary abdominal closure for trauma and intra-abdominal sepsis: Different patients, different outcomes.

Loftus TJ, Jordan JR, Croft CA, Smith RS, Efron PA, Mohr AM, Moore FA, Brakenridge SC.

J Trauma Acute Care Surg. 2017 Feb;82(2):345-350. doi: 10.1097/TA.0000000000001283.

49.

Improved outcomes following implementation of an acute gastrointestinal bleeding multidisciplinary protocol.

Loftus TJ, Go KL, Hughes SJ, Croft CA, Smith RS, Efron PA, Moore FA, Brakenridge SC, Mohr AM, Jordan JR.

J Trauma Acute Care Surg. 2017 Jul;83(1):41-46. doi: 10.1097/TA.0000000000001295.

50.

Minireview: Regulatory T Cells and Ovarian Cancer.

Singh M, Loftus T, Webb E, Benencia F.

Immunol Invest. 2016 Nov;45(8):712-720. Epub 2016 Jul 15. Review.

PMID:
27420920

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