Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 35

1.

Clinical validation of the next-generation sequencing-based Extended RAS Panel assay using metastatic colorectal cancer patient samples from the phase 3 PRIME study.

Udar N, Lofton-Day C, Dong J, Vavrek D, Jung AS, Meier K, Iyer A, Slaughter R, Gutekunst K, Bach BA, Peeters M, Douillard JY.

J Cancer Res Clin Oncol. 2018 Oct;144(10):2001-2010. doi: 10.1007/s00432-018-2688-3. Epub 2018 Jul 17.

2.

Final Analysis of Outcomes and RAS/BRAF Status in a Randomized Phase 3 Study of Panitumumab and Best Supportive Care in Chemorefractory Wild Type KRAS Metastatic Colorectal Cancer.

Kim TW, Elme A, Park JO, Udrea AA, Kim SY, Ahn JB, Valencia RV, Krishnan S, Manojlovic N, Guan X, Lofton-Day C, Jung AS, Vrdoljak E.

Clin Colorectal Cancer. 2018 Sep;17(3):206-214. doi: 10.1016/j.clcc.2018.03.008. Epub 2018 Mar 21.

3.

Diagnostic Quality Assurance Pilot: A Model to Demonstrate Comparative Laboratory Test Performance with an Oncology Companion Diagnostic Assay.

Zehnbauer B, Lofton-Day C, Pfeifer J, Shaughnessy E, Goh L.

J Mol Diagn. 2017 Jan;19(1):1-3. doi: 10.1016/j.jmoldx.2016.10.001.

PMID:
27993328
4.

A phase 3 trial evaluating panitumumab plus best supportive care vs best supportive care in chemorefractory wild-type KRAS or RAS metastatic colorectal cancer.

Kim TW, Elme A, Kusic Z, Park JO, Udrea AA, Kim SY, Ahn JB, Valencia RV, Krishnan S, Bilic A, Manojlovic N, Dong J, Guan X, Lofton-Day C, Jung AS, Vrdoljak E.

Br J Cancer. 2016 Nov 8;115(10):1206-1214. doi: 10.1038/bjc.2016.309. Epub 2016 Oct 13.

5.

The State of the Art in Colorectal Cancer Molecular Biomarker Testing.

Pillai RK, Lopategui JR, Dhall D, Guindi M, Slavin T, Lofton-Day CE, Patterson SD.

Adv Anat Pathol. 2016 Mar;23(2):92-103. doi: 10.1097/PAP.0000000000000107. Review.

6.

Validation of a real-time PCR-based qualitative assay for the detection of methylated SEPT9 DNA in human plasma.

Potter NT, Hurban P, White MN, Whitlock KD, Lofton-Day CE, Tetzner R, Koenig T, Quigley NB, Weiss G.

Clin Chem. 2014 Sep;60(9):1183-91. doi: 10.1373/clinchem.2013.221044. Epub 2014 Jun 17.

7.

Prospective evaluation of methylated SEPT9 in plasma for detection of asymptomatic colorectal cancer.

Church TR, Wandell M, Lofton-Day C, Mongin SJ, Burger M, Payne SR, Castaños-Vélez E, Blumenstein BA, Rösch T, Osborn N, Snover D, Day RW, Ransohoff DF; PRESEPT Clinical Study Steering Committee, Investigators and Study Team.

Gut. 2014 Feb;63(2):317-25. doi: 10.1136/gutjnl-2012-304149. Epub 2013 Feb 13.

8.

TFAP2E-DKK4 and chemoresistance in colorectal cancer.

Ebert MP, Tänzer M, Balluff B, Burgermeister E, Kretzschmar AK, Hughes DJ, Tetzner R, Lofton-Day C, Rosenberg R, Reinacher-Schick AC, Schulmann K, Tannapfel A, Hofheinz R, Röcken C, Keller G, Langer R, Specht K, Porschen R, Stöhlmacher-Williams J, Schuster T, Ströbel P, Schmid RM.

N Engl J Med. 2012 Jan 5;366(1):44-53. doi: 10.1056/NEJMoa1009473.

9.

Performance of epigenetic markers SEPT9 and ALX4 in plasma for detection of colorectal precancerous lesions.

Tänzer M, Balluff B, Distler J, Hale K, Leodolter A, Röcken C, Molnar B, Schmid R, Lofton-Day C, Schuster T, Ebert MP.

PLoS One. 2010 Feb 4;5(2):e9061. doi: 10.1371/journal.pone.0009061.

10.

Circulating methylated SEPT9 DNA in plasma is a biomarker for colorectal cancer.

deVos T, Tetzner R, Model F, Weiss G, Schuster M, Distler J, Steiger KV, Grützmann R, Pilarsky C, Habermann JK, Fleshner PR, Oubre BM, Day R, Sledziewski AZ, Lofton-Day C.

Clin Chem. 2009 Jul;55(7):1337-46. doi: 10.1373/clinchem.2008.115808. Epub 2009 Apr 30.

11.

Sensitive detection of colorectal cancer in peripheral blood by septin 9 DNA methylation assay.

Grützmann R, Molnar B, Pilarsky C, Habermann JK, Schlag PM, Saeger HD, Miehlke S, Stolz T, Model F, Roblick UJ, Bruch HP, Koch R, Liebenberg V, Devos T, Song X, Day RH, Sledziewski AZ, Lofton-Day C.

PLoS One. 2008;3(11):e3759. doi: 10.1371/journal.pone.0003759. Epub 2008 Nov 19.

12.

Distinct TPEF/HPP1 gene methylation patterns in gastric cancer indicate a field effect in gastric carcinogenesis.

Ivanauskas A, Hoffmann J, Jonaitis LV, Markelis R, Juozaityte E, Kupcinskas L, Lofton-Day C, Röcken C, Malfertheiner P.

Dig Liver Dis. 2008 Dec;40(12):920-6. doi: 10.1016/j.dld.2008.05.004. Epub 2008 Sep 16.

PMID:
18799374
13.

DNA methylation biomarkers for blood-based colorectal cancer screening.

Lofton-Day C, Model F, Devos T, Tetzner R, Distler J, Schuster M, Song X, Lesche R, Liebenberg V, Ebert M, Molnar B, Grützmann R, Pilarsky C, Sledziewski A.

Clin Chem. 2008 Feb;54(2):414-23. Epub 2007 Dec 18.

14.

Comparative DNA methylation analysis in normal and tumour tissues and in cancer cell lines using differential methylation hybridisation.

Lewin J, Plum A, Hildmann T, Rujan T, Eckhardt F, Liebenberg V, Lofton-Day C, Wasserkort R.

Int J Biochem Cell Biol. 2007;39(7-8):1539-50. Epub 2007 Mar 15.

PMID:
17499000
15.

Identification and validation of colorectal neoplasia-specific methylation markers for accurate classification of disease.

Model F, Osborn N, Ahlquist D, Gruetzmann R, Molnar B, Sipos F, Galamb O, Pilarsky C, Saeger HD, Tulassay Z, Hale K, Mooney S, Lograsso J, Adorjan P, Lesche R, Dessauer A, Kleiber J, Porstmann B, Sledziewski A, Lofton-Day C.

Mol Cancer Res. 2007 Feb;5(2):153-63.

16.

Aristaless-like homeobox-4 gene methylation is a potential marker for colorectal adenocarcinomas.

Ebert MP, Model F, Mooney S, Hale K, Lograsso J, Tonnes-Priddy L, Hoffmann J, Csepregi A, Röcken C, Molnar B, Schulz HU, Malfertheiner P, Lofton-Day C.

Gastroenterology. 2006 Nov;131(5):1418-30. Epub 2006 Aug 18.

PMID:
17101318
17.

Aberrant methylation of the eyes absent 4 gene in ulcerative colitis-associated dysplasia.

Osborn NK, Zou H, Molina JR, Lesche R, Lewin J, Lofton-Day C, Klatt KK, Harrington JJ, Burgart LJ, Ahlquist DA.

Clin Gastroenterol Hepatol. 2006 Feb;4(2):212-8.

PMID:
16469682
18.

Hypermethylation of the TPEF/HPP1 gene in primary and metastatic colorectal cancers.

Ebert MP, Mooney SH, Tonnes-Priddy L, Lograsso J, Hoffmann J, Chen J, Röcken C, Schulz HU, Malfertheiner P, Lofton-Day C.

Neoplasia. 2005 Aug;7(8):771-8.

19.

Molecular analysis of APC promoter methylation and protein expression in colorectal cancer metastasis.

Chen J, Röcken C, Lofton-Day C, Schulz HU, Müller O, Kutzner N, Malfertheiner P, Ebert MP.

Carcinogenesis. 2005 Jan;26(1):37-43. Epub 2004 Sep 16.

PMID:
15375009
21.

Expressed CpG island sequence tag microarray for dual screening of DNA hypermethylation and gene silencing in cancer cells.

Shi H, Yan PS, Chen CM, Rahmatpanah F, Lofton-Day C, Caldwell CW, Huang TH.

Cancer Res. 2002 Jun 1;62(11):3214-20.

22.

Identification and characterization of an isoform of murine Mpl.

Sabath DF, Lofton-Day C, Lin N, Lok S, Kaushansky K, Broudy VC.

Biochim Biophys Acta. 2002 Apr 12;1574(3):383-6.

PMID:
11997107
23.

Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function.

Parrish-Novak J, Dillon SR, Nelson A, Hammond A, Sprecher C, Gross JA, Johnston J, Madden K, Xu W, West J, Schrader S, Burkhead S, Heipel M, Brandt C, Kuijper JL, Kramer J, Conklin D, Presnell SR, Berry J, Shiota F, Bort S, Hambly K, Mudri S, Clegg C, Moore M, Grant FJ, Lofton-Day C, Gilbert T, Rayond F, Ching A, Yao L, Smith D, Webster P, Whitmore T, Maurer M, Kaushansky K, Holly RD, Foster D.

Nature. 2000 Nov 2;408(6808):57-63.

PMID:
11081504
24.

Human secretin (SCT): gene structure, chromosome location, and distribution of mRNA.

Whitmore TE, Holloway JL, Lofton-Day CE, Maurer MF, Chen L, Quinton TJ, Vincent JB, Scherer SW, Lok S.

Cytogenet Cell Genet. 2000;90(1-2):47-52.

PMID:
11060443
25.

Identification of INSL6, a new member of the insulin family that is expressed in the testis of the human and rat.

Lok S, Johnston DS, Conklin D, Lofton-Day CE, Adams RL, Jelmberg AC, Whitmore TE, Schrader S, Griswold MD, Jaspers SR.

Biol Reprod. 2000 Jun;62(6):1593-9.

PMID:
10819760
26.

TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease.

Gross JA, Johnston J, Mudri S, Enselman R, Dillon SR, Madden K, Xu W, Parrish-Novak J, Foster D, Lofton-Day C, Moore M, Littau A, Grossman A, Haugen H, Foley K, Blumberg H, Harrison K, Kindsvogel W, Clegg CH.

Nature. 2000 Apr 27;404(6781):995-9.

PMID:
10801128
27.

Identification of INSL5, a new member of the insulin superfamily.

Conklin D, Lofton-Day CE, Haldeman BA, Ching A, Whitmore TE, Lok S, Jaspers S.

Genomics. 1999 Aug 15;60(1):50-6.

PMID:
10458910
28.

A novel human GnRH receptor homolog gene: abundant and wide tissue distribution of the antisense transcript.

Millar R, Conklin D, Lofton-Day C, Hutchinson E, Troskie B, Illing N, Sealfon SC, Hapgood J.

J Endocrinol. 1999 Jul;162(1):117-26.

PMID:
10396028
30.

Do the preclinical effects of thrombopoietin correlate with its in vitro properties?

Kaushansky K, Broudy VC, Sitnicka E, Lofton-Day C, Grossmann A, Sprugel K.

Stem Cells. 1996;14 Suppl 1:108-11. Review.

31.

Recombinant ob protein reduces feeding and body weight in the ob/ob mouse.

Weigle DS, Bukowski TR, Foster DC, Holderman S, Kramer JM, Lasser G, Lofton-Day CE, Prunkard DE, Raymond C, Kuijper JL.

J Clin Invest. 1995 Oct;96(4):2065-70.

32.

Thrombopoietin, the Mp1 ligand, is essential for full megakaryocyte development.

Kaushansky K, Broudy VC, Lin N, Jorgensen MJ, McCarty J, Fox N, Zucker-Franklin D, Lofton-Day C.

Proc Natl Acad Sci U S A. 1995 Apr 11;92(8):3234-8.

33.

Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo.

Lok S, Kaushansky K, Holly RD, Kuijper JL, Lofton-Day CE, Oort PJ, Grant FJ, Heipel MD, Burkhead SK, Kramer JM, et al.

Nature. 1994 Jun 16;369(6481):565-8.

PMID:
8202158
34.

Complete cDNA encoding human phospholipid transfer protein from human endothelial cells.

Day JR, Albers JJ, Lofton-Day CE, Gilbert TL, Ching AF, Grant FJ, O'Hara PJ, Marcovina SM, Adolphson JL.

J Biol Chem. 1994 Mar 25;269(12):9388-91.

35.

Molecular cloning and sequence analysis of the cDNA encoding human apolipoprotein H (beta 2-glycoprotein I).

Day JR, O'Hara PJ, Grant FJ, Lofton-Day C, Berkaw MN, Werner P, Arnaud P.

Int J Clin Lab Res. 1992;21(3):256-63.

PMID:
1339416

Supplemental Content

Loading ...
Support Center