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Items: 21

1.

Phase I study of RGB-286638, a novel, multitargeted cyclin-dependent kinase inhibitor in patients with solid tumors.

van der Biessen DA, Burger H, de Bruijn P, Lamers CH, Naus N, Loferer H, Wiemer EA, Mathijssen RH, de Jonge MJ.

Clin Cancer Res. 2014 Sep 15;20(18):4776-83. doi: 10.1158/1078-0432.CCR-14-0325. Epub 2014 Jul 14.

2.

Small-molecule multi-targeted kinase inhibitor RGB-286638 triggers P53-dependent and -independent anti-multiple myeloma activity through inhibition of transcriptional CDKs.

Cirstea D, Hideshima T, Santo L, Eda H, Mishima Y, Nemani N, Hu Y, Mimura N, Cottini F, Gorgun G, Ohguchi H, Suzuki R, Loferer H, Munshi NC, Anderson KC, Raje N.

Leukemia. 2013 Dec;27(12):2366-75. doi: 10.1038/leu.2013.194. Epub 2013 Jun 28.

3.

Prediction of mechanisms of action of antibacterial compounds by gene expression profiling.

Hutter B, Schaab C, Albrecht S, Borgmann M, Brunner NA, Freiberg C, Ziegelbauer K, Rock CO, Ivanov I, Loferer H.

Antimicrob Agents Chemother. 2004 Aug;48(8):2838-44.

4.

Panel of Bacillus subtilis reporter strains indicative of various modes of action.

Hutter B, Fischer C, Jacobi A, Schaab C, Loferer H.

Antimicrob Agents Chemother. 2004 Jul;48(7):2588-94.

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DNA microarray technology and antimicrobial drug discovery.

Ivanov I, Schaab C, Planitzer S, Teichmann U, Machl A, Theml S, Meier-Ewert S, Seizinger B, Loferer H.

Pharmacogenomics. 2000 May;1(2):169-78. Review.

PMID:
11256588
8.

Mining bacterial genomes for antimicrobial targets.

Loferer H.

Mol Med Today. 2000 Dec;6(12):470-4. Review.

PMID:
11099952
9.

A genome-based approach for the identification of essential bacterial genes.

Arigoni F, Talabot F, Peitsch M, Edgerton MD, Meldrum E, Allet E, Fish R, Jamotte T, Curchod ML, Loferer H.

Nat Biotechnol. 1998 Sep;16(9):851-6.

PMID:
9743119
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Bradyrhizobium japonicum cytochrome c550 is required for nitrate respiration but not for symbiotic nitrogen fixation.

Bott M, Thöny-Meyer L, Loferer H, Rossbach S, Tully RE, Keister D, Appleby CA, Hennecke H.

J Bacteriol. 1995 Apr;177(8):2214-7.

14.

Bacterial genes and proteins involved in the biogenesis of c-type cytochromes and terminal oxidases.

Thöny-Meyer L, Loferer H, Ritz D, Hennecke H.

Biochim Biophys Acta. 1994 Aug 30;1187(2):260-3.

PMID:
8075119
16.

Protein disulphide oxidoreductases in bacteria.

Loferer H, Hennecke H.

Trends Biochem Sci. 1994 Apr;19(4):169-71. Review.

PMID:
8016867
18.

Cloning, sequencing and mutational analysis of the cytochrome c552 gene (cycB) from Bradyrhizobium japonicum strain 110.

Rossbach S, Loferer H, Acuña G, Appleby CA, Hennecke H.

FEMS Microbiol Lett. 1991 Oct 1;67(2):145-52.

PMID:
1663888
19.

Radiation-induced activation of transcription factors in mammalian cells.

Krämer M, Stein B, Mai S, Kunz E, König H, Loferer H, Grunicke HH, Ponta H, Herrlich P, Rahmsdorf HJ.

Radiat Environ Biophys. 1990;29(4):303-13. Review.

PMID:
2281136
20.

Mechanism and biological significance of the Ha-ras-induced activation of the Na+/H(+)-antiporter.

Maly K, Hochleitner B, Uberall F, Loferer H, Oberhuber H, Doppler W, Grunicke H.

Adv Enzyme Regul. 1990;30:63-74.

PMID:
2169700
21.

Ha-ras activates the Na+/H+ antiporter by a protein kinase C-independent mechanism.

Maly K, Uberall F, Loferer H, Doppler W, Oberhuber H, Groner B, Grunicke HH.

J Biol Chem. 1989 Jul 15;264(20):11839-42.

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