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Items: 1 to 50 of 76

1.

A clinical assessment and lung tissue burden from an individual who worked as a Libby vermiculite miner.

Black B, Dodson RF, Bruce JR, Poye LW, Henschke C, Loewen G.

Inhal Toxicol. 2017 Aug;29(9):404-413. doi: 10.1080/08958378.2017.1372536. Epub 2017 Oct 17.

PMID:
29039215
2.

Single Dose and Repeat Once-Daily Dose Safety, Tolerability and Pharmacokinetics of Valbenazine in Healthy Male Subjects.

Luo R, Bozigian H, Jimenez R, Loewen G, O'Brien CF.

Psychopharmacol Bull. 2017 Aug 1;47(3):44-52.

3.

Differences in Dihydrotetrabenazine Isomer Concentrations Following Administration of Tetrabenazine and Valbenazine.

Skor H, Smith EB, Loewen G, O'Brien CF, Grigoriadis DE, Bozigian H.

Drugs R D. 2017 Sep;17(3):449-459. doi: 10.1007/s40268-017-0202-z.

4.

Progranulin Levels in Plasma and Cerebrospinal Fluid in Granulin Mutation Carriers.

Meeter LH, Patzke H, Loewen G, Dopper EG, Pijnenburg YA, van Minkelen R, van Swieten JC.

Dement Geriatr Cogn Dis Extra. 2016 Jul 22;6(2):330-340. eCollection 2016 May-Aug.

5.

Global marine pollutants inhibit P-glycoprotein: Environmental levels, inhibitory effects, and cocrystal structure.

Nicklisch SC, Rees SD, McGrath AP, Gökirmak T, Bonito LT, Vermeer LM, Cregger C, Loewen G, Sandin S, Chang G, Hamdoun A.

Sci Adv. 2016 Apr 15;2(4):e1600001. doi: 10.1126/sciadv.1600001. eCollection 2016 Apr.

6.

A Phase I Study of Light Dose for Photodynamic Therapy Using 2-[1-Hexyloxyethyl]-2 Devinyl Pyropheophorbide-a for the Treatment of Non-Small Cell Carcinoma In Situ or Non-Small Cell Microinvasive Bronchogenic Carcinoma: A Dose Ranging Study.

Dhillon SS, Demmy TL, Yendamuri S, Loewen G, Nwogu C, Cooper M, Henderson BW.

J Thorac Oncol. 2016 Feb;11(2):234-41. doi: 10.1016/j.jtho.2015.10.020. Epub 2015 Dec 22.

7.

Vitamin D and Dental Caries in Children.

Schroth RJ, Rabbani R, Loewen G, Moffatt ME.

J Dent Res. 2016 Feb;95(2):173-9. doi: 10.1177/0022034515616335. Epub 2015 Nov 9.

PMID:
26553883
8.

Membrane Assays to Characterize Interaction of Drugs with ABCB1.

Fekete Z, Rajnai Z, Nagy T, Jakab KT, Kurunczi A, Gémes K, Herédi-Szabó K, Fülöp F, Tóth GK, Czerwinski M, Loewen G, Krajcsi P.

J Membr Biol. 2015 Dec;248(6):967-77. doi: 10.1007/s00232-015-9804-y. Epub 2015 Apr 30.

PMID:
25926125
9.

lincRNA HOTAIR as a novel promoter of cancer progression.

Loewen G, Zhuo Y, Zhuang Y, Jayawickramarajah J, Shan B.

J Can Res Updates. 2014 Jul;3(3):134-140.

10.

Functions of lncRNA HOTAIR in lung cancer.

Loewen G, Jayawickramarajah J, Zhuo Y, Shan B.

J Hematol Oncol. 2014 Dec 10;7:90. doi: 10.1186/s13045-014-0090-4. Review.

11.

Comparison of performance status with peak oxygen consumption in operable patients with non-small-cell lung cancer.

Roman MA, Koelwyn GJ, Eves ND, Hornsby WE, Watson D, Herndon Ii JE, Kohman L, Loewen G, Jones LW.

Respirology. 2014 Jan;19(1):105-8. doi: 10.1111/resp.12162.

12.

Lung cancer screening update.

Dhillon SS, Loewen G, Jayaprakash V, Reid ME.

J Carcinog. 2013 Jan 31;12:2. doi: 10.4103/1477-3163.106681. Print 2013.

13.

The pre-clinical absorption, distribution, metabolism and excretion properties of IPI-926, an orally bioavailable antagonist of the hedgehog signal transduction pathway.

Smith S, Hoyt J, Whitebread N, Manna J, Peluso M, Faia K, Campbell V, Tremblay M, Nair S, Grogan M, Castro A, Campbell M, Ferguson J, Arsenault B, Nevejans J, Carter B, Lee J, Dunbar J, McGovern K, Read M, Adams J, Constan A, Loewen G, Sydor J, Palombella V, Soglia J.

Xenobiotica. 2013 Oct;43(10):875-85. doi: 10.3109/00498254.2013.780671. Epub 2013 Mar 25.

PMID:
23527529
14.

Lysosomal sequestration (trapping) of lipophilic amine (cationic amphiphilic) drugs in immortalized human hepatocytes (Fa2N-4 cells).

Kazmi F, Hensley T, Pope C, Funk RS, Loewen GJ, Buckley DB, Parkinson A.

Drug Metab Dispos. 2013 Apr;41(4):897-905. doi: 10.1124/dmd.112.050054. Epub 2013 Feb 1.

15.

Bioavailability of intranasal vs. rectal diazepam.

Ivaturi V, Kriel R, Brundage R, Loewen G, Mansbach H, Cloyd J.

Epilepsy Res. 2013 Feb;103(2-3):254-61. doi: 10.1016/j.eplepsyres.2012.07.018. Epub 2012 Sep 13.

PMID:
22981338
16.

Peak oxygen consumption and long-term all-cause mortality in nonsmall cell lung cancer.

Jones LW, Watson D, Herndon JE 2nd, Eves ND, Haithcock BE, Loewen G, Kohman L.

Cancer. 2010 Oct 15;116(20):4825-32. doi: 10.1002/cncr.25396.

17.

Detection and localization of intraepithelial neoplasia and invasive carcinoma using fluorescence-reflectance bronchoscopy: an international, multicenter clinical trial.

Edell E, Lam S, Pass H, Miller YE, Sutedja T, Kennedy T, Loewen G, Keith RL, Gazdar A.

J Thorac Oncol. 2009 Jan;4(1):49-54. doi: 10.1097/JTO.0b013e3181914506. Erratum in: J Thorac Oncol. 2009 Apr;4(4):558. Gazdar, Adi [added].

18.

Hormone replacement therapy as a risk factor for non-small cell lung cancer: results of a case-control study.

Ramnath N, Menezes RJ, Loewen G, Dua P, Eid F, Alkhaddo J, Paganelli G, Natarajan N, Reid ME.

Oncology. 2007;73(5-6):305-10. doi: 10.1159/000134238. Epub 2008 May 21.

PMID:
18493157
19.

Vitamin D receptor expression in normal, premalignant, and malignant human lung tissue.

Menezes RJ, Cheney RT, Husain A, Tretiakova M, Loewen G, Johnson CS, Jayaprakash V, Moysich KB, Salgia R, Reid ME.

Cancer Epidemiol Biomarkers Prev. 2008 May;17(5):1104-10. doi: 10.1158/1055-9965.EPI-07-2713.

20.

Administration of morphine sulfate extended-release capsules via gastrostomy: dissolution study and case reports.

Shaiova L, Mori M, Anderson K, Loewen G, Ghalie R, Homel P, Portenoy R.

J Palliat Med. 2007 Oct;10(5):1063-7.

PMID:
17985962
21.

Preoperative exercise Vo2 measurement for lung resection candidates: results of Cancer and Leukemia Group B Protocol 9238.

Loewen GM, Watson D, Kohman L, Herndon JE 2nd, Shennib H, Kernstine K, Olak J, Mador MJ, Harpole D, Sugarbaker D, Green M; Cancer and Leukemia Group B.

J Thorac Oncol. 2007 Jul;2(7):619-25.

22.

Cross-linking of signal transducer and activator of transcription 3--a molecular marker for the photodynamic reaction in cells and tumors.

Henderson BW, Daroqui C, Tracy E, Vaughan LA, Loewen GM, Cooper MT, Baumann H.

Clin Cancer Res. 2007 Jun 1;13(11):3156-63.

23.

Approaches to tobacco control & lung cancer screening among physician assistants.

Lawvere S, Mahoney MC, Englert J, Murphy J, Hyland A, Loewen G, Mirand A.

J Cancer Educ. 2006 Winter;21(4):248-52.

PMID:
17542718
24.

Pneumonectomy for bronchogenic carcinoma: analysis of factors predicting survival.

Ramnath N, Demmy TL, Antun A, Natarajan N, Nwogu CE, Loewen GM, Reid ME.

Ann Thorac Surg. 2007 May;83(5):1831-6.

PMID:
17462408
25.

Autofluorescence bronchoscopy for lung cancer surveillance based on risk assessment.

Loewen G, Natarajan N, Tan D, Nava E, Klippenstein D, Mahoney M, Cummings M, Reid M.

Thorax. 2007 Apr;62(4):335-40. Epub 2006 Nov 13.

26.

CYP4F enzymes are the major enzymes in human liver microsomes that catalyze the O-demethylation of the antiparasitic prodrug DB289 [2,5-bis(4-amidinophenyl)furan-bis-O-methylamidoxime].

Wang MZ, Saulter JY, Usuki E, Cheung YL, Hall M, Bridges AS, Loewen G, Parkinson OT, Stephens CE, Allen JL, Zeldin DC, Boykin DW, Tidwell RR, Parkinson A, Paine MF, Hall JE.

Drug Metab Dispos. 2006 Dec;34(12):1985-94. Epub 2006 Sep 22.

27.

Endobronchial photodynamic therapy for lung cancer.

Loewen GM, Pandey R, Bellnier D, Henderson B, Dougherty T.

Lasers Surg Med. 2006 Jun;38(5):364-70. Review.

PMID:
16788932
28.

Characterization of cell-type specific profiles in tissues and isolated cells from squamous cell carcinomas of the lung.

Hawthorn L, Stein L, Panzarella J, Loewen GM, Baumann H.

Lung Cancer. 2006 Aug;53(2):129-42. Epub 2006 Jun 6.

PMID:
16757060
29.
30.

Transformation of human bronchial epithelial cells alters responsiveness to inflammatory cytokines.

Loewen GM, Tracy E, Blanchard F, Tan D, Yu J, Raza S, Matsui S, Baumann H.

BMC Cancer. 2005 Nov 4;5:145.

31.

Mild skin photosensitivity in cancer patients following injection of Photochlor (2-[1-hexyloxyethyl]-2-devinyl pyropheophorbide-a; HPPH) for photodynamic therapy.

Bellnier DA, Greco WR, Nava H, Loewen GM, Oseroff AR, Dougherty TJ.

Cancer Chemother Pharmacol. 2006 Jan;57(1):40-5. Epub 2005 Nov 5.

PMID:
16001178
32.

Upregulation of the tissue inhibitor of metalloproteinase-1 protein is associated with progression of human non-small-cell lung cancer.

Aljada IS, Ramnath N, Donohue K, Harvey S, Brooks JJ, Wiseman SM, Khoury T, Loewen G, Slocum HK, Anderson TM, Bepler G, Tan D.

J Clin Oncol. 2004 Aug 15;22(16):3218-29. Epub 2004 Jul 12.

PMID:
15249585
33.

Bimodality lung cancer screening in high-risk patients: a preliminary report.

Loewen G, Reid M, Tan D, Klippenstein D, Nava E, Natarajan R, Mahoney M.

Chest. 2004 May;125(5 Suppl):163S-4S. No abstract available.

PMID:
15136489
34.

The evolution of lung cancer screening.

Wilkinson NW, Loewen GM, Klippenstein DL, Litwin AM, Anderson TM.

J Surg Oncol. 2003 Dec;84(4):234-8. Review.

PMID:
14756435
35.

HER-2/neu protein expression and gene alteration in stage I-IIIA non-small-cell lung cancer: a study of 140 cases using a combination of high throughput tissue microarray, immunohistochemistry, and fluorescent in situ hybridization.

Tan D, Deeb G, Wang J, Slocum HK, Winston J, Wiseman S, Beck A, Sait S, Anderson T, Nwogu C, Ramnath N, Loewen G.

Diagn Mol Pathol. 2003 Dec;12(4):201-11.

PMID:
14639106
36.

Nurse practitioners' knowledge, practice and attitudes about tobacco cessation & lung cancer screening.

Lawvere S, Mahoney MC, Englert JJ, Murphy JM, Hyland A, Klein SB, Loewen GM.

J Am Acad Nurse Pract. 2003 Aug;15(8):376-81.

PMID:
14509103
37.

Thyroid transcription factor-1 expression prevalence and its clinical implications in non-small cell lung cancer: a high-throughput tissue microarray and immunohistochemistry study.

Tan D, Li Q, Deeb G, Ramnath N, Slocum HK, Brooks J, Cheney R, Wiseman S, Anderson T, Loewen G.

Hum Pathol. 2003 Jun;34(6):597-604.

PMID:
12827614
38.

Population pharmacokinetics of the photodynamic therapy agent 2-[1-hexyloxyethyl]-2-devinyl pyropheophorbide-a in cancer patients.

Bellnier DA, Greco WR, Loewen GM, Nava H, Oseroff AR, Pandey RK, Tsuchida T, Dougherty TJ.

Cancer Res. 2003 Apr 15;63(8):1806-13.

39.

Effect of concurrent radiation therapy and chemotherapy on pulmonary function in patients with esophageal cancer: dose-volume histogram analysis.

Gergel TJ, Leichman L, Nava HR, Blumenson LE, Loewen GM, Gibbs JE, Khushalani NI, Leichman CG, Bodnar LM, Douglass HO, Smith JL, Kuettel MR, Proulx GM.

Cancer J. 2002 Nov-Dec;8(6):451-60.

PMID:
12500854
40.

Regular aspirin use and lung cancer risk.

Moysich KB, Menezes RJ, Ronsani A, Swede H, Reid ME, Cummings KM, Falkner KL, Loewen GM, Bepler G.

BMC Cancer. 2002 Nov 26;2:31. Epub 2002 Nov 26.

41.

Validated liquid chromatographic method for the determination of bexarotene in human plasma.

van de Merbel NC, van Veen JH, Wilkens G, Loewen G.

J Chromatogr B Analyt Technol Biomed Life Sci. 2002 Aug 5;775(2):189-95.

PMID:
12113985
43.

Pharmacokinetic evaluation of a sprinkle-dose regimen of a once-daily, extended-release morphine formulation.

Eliot L, Butler J, Devane J, Loewen G.

Clin Ther. 2002 Feb;24(2):260-8.

PMID:
11911556
44.

MCM2--a promising marker for premalignant lesions of the lung: a cohort study.

Tan DF, Huberman JA, Hyland A, Loewen GM, Brooks JS, Beck AF, Todorov IT, Bepler G.

BMC Cancer. 2001;1:6. Epub 2001 Jun 25.

45.

A phase I-II study of 9-cis retinoic acid and interferon-alpha2b in patients with advanced renal-cell carcinoma: an NCIC Clinical Trials Group study.

Miller WH Jr, Reyno LM, Loewen GR, Huan S, Winquist E, Moore M, Cato A 3rd, Jaunakais D, Truglia JA, Matthews S, Dancey J, Eisenhauer E.

Ann Oncol. 2000 Nov;11(11):1387-9.

PMID:
11142476
46.

Topical treatment of cutaneous lesions of acquired immunodeficiency syndrome-related Kaposi sarcoma using alitretinoin gel: results of phase 1 and 2 trials.

Duvic M, Friedman-Kien AE, Looney DJ, Miles SA, Myskowski PL, Scadden DT, Von Roenn J, Galpin JE, Groopman J, Loewen G, Stevens V, Truglia JA, Yocum RC.

Arch Dermatol. 2000 Dec;136(12):1461-9.

PMID:
11115156
47.

A Phase I study of LGD1069 in adults with advanced cancer.

Rizvi NA, Marshall JL, Dahut W, Ness E, Truglia JA, Loewen G, Gill GM, Ulm EH, Geiser R, Jaunakais D, Hawkins MJ.

Clin Cancer Res. 1999 Jul;5(7):1658-64.

48.

Preliminary phase II clinical and pharmacokinetic study of 9-cis retinoic acid in advanced cervical cancer. New York Gynecologic Oncology Group.

Wadler S, Schwartz EL, Anderson P, Runowicz CD, Chuang L, Del Priore G, Hochster H, Goldberg G, Fields A, Loewen G, Haynes H.

Cancer J Sci Am. 1999 May-Jun;5(3):165-70.

PMID:
10367173
49.

Phase I study of 9-cis-retinoic acid (ALRT1057 capsules) in adults with advanced cancer.

Rizvi NA, Marshall JL, Ness E, Yoe J, Gill GM, Truglia JA, Loewen GR, Jaunakais D, Ulm EH, Hawkins MJ.

Clin Cancer Res. 1998 Jun;4(6):1437-42.

50.

Gloeolactone, a New Epoxy Lactone from a Blue-Green Alga

Stierle DB, Stierle AA, Bugni T, Loewen G.

J Nat Prod. 1998 Feb 27;61(2):251-2.

PMID:
9548854

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