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Items: 25


Phosphatidylinositol 3,4-bisphosphate synthesis and turnover are spatially segregated in the endocytic pathway.

Wang H, Loerke D, Bruns C, Müller R, Koch PA, Puchkov D, Schultz C, Haucke V.

J Biol Chem. 2019 Dec 12. pii: jbc.RA119.011774. doi: 10.1074/jbc.RA119.011774. [Epub ahead of print]


Nanoscale coupling of endocytic pit growth and stability.

Lehmann M, Lukonin I, Noé F, Schmoranzer J, Clementi C, Loerke D, Haucke V.

Sci Adv. 2019 Nov 27;5(11):eaax5775. doi: 10.1126/sciadv.aax5775. eCollection 2019 Nov.


Viscoelastic voyages - Biophysical perspectives on cell intercalation during Drosophila gastrulation.

Loerke D, Blankenship JT.

Semin Cell Dev Biol. 2019 Nov 26. pii: S1084-9521(19)30033-3. doi: 10.1016/j.semcdb.2019.11.005. [Epub ahead of print] Review.


Cell ratcheting through the Sbf RabGEF directs force balancing and stepped apical constriction.

Miao H, Vanderleest TE, Jewett CE, Loerke D, Blankenship JT.

J Cell Biol. 2019 Nov 4;218(11):3845-3860. doi: 10.1083/jcb.201905082. Epub 2019 Sep 27.


Vertex sliding drives intercalation by radial coupling of adhesion and actomyosin networks during Drosophila germband extension.

Vanderleest TE, Smits CM, Xie Y, Jewett CE, Blankenship JT, Loerke D.

Elife. 2018 Jul 9;7. pii: e34586. doi: 10.7554/eLife.34586.


Planar polarized Rab35 functions as an oscillatory ratchet during cell intercalation in the Drosophila epithelium.

Jewett CE, Vanderleest TE, Miao H, Xie Y, Madhu R, Loerke D, Blankenship JT.

Nat Commun. 2017 Sep 7;8(1):476. doi: 10.1038/s41467-017-00553-0.


Regulation of clathrin-mediated endocytosis by hierarchical allosteric activation of AP2.

Kadlecova Z, Spielman SJ, Loerke D, Mohanakrishnan A, Reed DK, Schmid SL.

J Cell Biol. 2017 Jan 2;216(1):167-179. doi: 10.1083/jcb.201608071. Epub 2016 Dec 21.


Rab8 directs furrow ingression and membrane addition during epithelial formation in Drosophila melanogaster.

Mavor LM, Miao H, Zuo Z, Holly RM, Xie Y, Loerke D, Blankenship JT.

Development. 2016 Mar 1;143(5):892-903. doi: 10.1242/dev.128876. Epub 2016 Feb 2.


Exocyst-Dependent Membrane Addition Is Required for Anaphase Cell Elongation and Cytokinesis in Drosophila.

Giansanti MG, Vanderleest TE, Jewett CE, Sechi S, Frappaolo A, Fabian L, Robinett CC, Brill JA, Loerke D, Fuller MT, Blankenship JT.

PLoS Genet. 2015 Nov 3;11(11):e1005632. doi: 10.1371/journal.pgen.1005632. eCollection 2015 Nov.


Quantitative imaging of epithelial cell scattering identifies specific inhibitors of cell motility and cell-cell dissociation.

Loerke D, le Duc Q, Blonk I, Kerstens A, Spanjaard E, Machacek M, Danuser G, de Rooij J.

Sci Signal. 2012 Jul 3;5(231):rs5. doi: 10.1126/scisignal.2002677.


RAB-5 controls the cortical organization and dynamics of PAR proteins to maintain C. elegans early embryonic polarity.

Hyenne V, Tremblay-Boudreault T, Velmurugan R, Grant BD, Loerke D, Labbé JC.

PLoS One. 2012;7(4):e35286. doi: 10.1371/journal.pone.0035286. Epub 2012 Apr 24.


Hotspots organize clathrin-mediated endocytosis by efficient recruitment and retention of nucleating resources.

Nunez D, Antonescu C, Mettlen M, Liu A, Schmid SL, Loerke D, Danuser G.

Traffic. 2011 Dec;12(12):1868-78. doi: 10.1111/j.1600-0854.2011.01273.x. Epub 2011 Sep 30.


Measuring the hierarchy of molecular events during clathrin-mediated endocytosis.

Loerke D, Mettlen M, Schmid SL, Danuser G.

Traffic. 2011 Jul;12(7):815-25. doi: 10.1111/j.1600-0854.2011.01197.x. Epub 2011 Apr 21.


Cargo- and adaptor-specific mechanisms regulate clathrin-mediated endocytosis.

Mettlen M, Loerke D, Yarar D, Danuser G, Schmid SL.

J Cell Biol. 2010 Mar 22;188(6):919-33. doi: 10.1083/jcb.200908078. Epub 2010 Mar 15.


Global and local regulation of clathrin-coated pit dynamics detected on patterned substrates.

Liu AP, Loerke D, Schmid SL, Danuser G.

Biophys J. 2009 Aug 19;97(4):1038-47. doi: 10.1016/j.bpj.2009.06.003.


Endocytic accessory proteins are functionally distinguished by their differential effects on the maturation of clathrin-coated pits.

Mettlen M, Stoeber M, Loerke D, Antonescu CN, Danuser G, Schmid SL.

Mol Biol Cell. 2009 Jul;20(14):3251-60. doi: 10.1091/mbc.E09-03-0256. Epub 2009 May 20.


Cargo and dynamin regulate clathrin-coated pit maturation.

Loerke D, Mettlen M, Yarar D, Jaqaman K, Jaqaman H, Danuser G, Schmid SL.

PLoS Biol. 2009 Mar 17;7(3):e57. doi: 10.1371/journal.pbio.1000057.


Robust single-particle tracking in live-cell time-lapse sequences.

Jaqaman K, Loerke D, Mettlen M, Kuwata H, Grinstein S, Schmid SL, Danuser G.

Nat Methods. 2008 Aug;5(8):695-702. doi: 10.1038/nmeth.1237. Epub 2008 Jul 20.


Probing intracellular force distributions by high-resolution live cell imaging and inverse dynamics.

Ji L, Loerke D, Gardel M, Danuser G.

Methods Cell Biol. 2007;83:199-235.


Differential control of clathrin subunit dynamics measured with EW-FRAP microscopy.

Loerke D, Wienisch M, Kochubey O, Klingauf J.

Traffic. 2005 Oct;6(10):918-29.


Quantifying axial secretory-granule motion with variable-angle evanescent-field excitation.

Loerke D, Stühmer W, Oheim M.

J Neurosci Methods. 2002 Sep 15;119(1):65-73.


Super-resolution measurements with evanescent-wave fluorescence excitation using variable beam incidence.

Loerke D, Preitz B, Stühmer W, Oheim M.

J Biomed Opt. 2000 Jan;5(1):23-30. Review.


Evanescent-wave microscopy: a new tool to gain insight into the control of transmitter release.

Oheim M, Loerke D, Chow RH, Stühmer W.

Philos Trans R Soc Lond B Biol Sci. 1999 Feb 28;354(1381):307-18. Review.


Multiple stimulation-dependent processes regulate the size of the releasable pool of vesicles.

Oheim M, Loerke D, Stühmer W, Chow RH.

Eur Biophys J. 1999;28(2):91-101.


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