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Development and evaluation of a whole blood-based approach for flow cytometric quantification of CD154+ mould-reactive T cells.

Weis P, Helm J, Page L, Lauruschkat CD, Lazariotou M, Einsele H, Loeffler J, Ullmann AJ, Wurster S.

Med Mycol. 2019 May 16. pii: myz038. doi: 10.1093/mmy/myz038. [Epub ahead of print]


Long-term outcomes and late adverse effects of a prospective study on proton radiotherapy for patients with low-grade glioma.

Tabrizi S, Yeap BY, Sherman JC, Nachtigall LB, Colvin MK, Dworkin M, Fullerton BC, Daartz J, Royce TJ, Oh KS, Batchelor TT, Curry WT, Loeffler JS, Shih HA.

Radiother Oncol. 2019 May 10;137:95-101. doi: 10.1016/j.radonc.2019.04.027. [Epub ahead of print]


Antifungal-resistant Mucorales in different indoor environments.

Caetano LA, Faria T, Springer J, Loeffler J, Viegas C.

Mycology. 2018 Nov 26;10(2):75-83. doi: 10.1080/21501203.2018.1551251. eCollection 2019 Jun.


Give Me Five? Examining the Psychophysiological Effects of High-Fives in Athletes.

Lautenbach F, Jeraj D, Loeffler J, Musculus L.

Appl Psychophysiol Biofeedback. 2019 Apr 12. doi: 10.1007/s10484-019-09435-1. [Epub ahead of print]


Anomalous pacing in a biventricular device due to spontaneous premature beats: What is the mechanism?

Larsen TR, Saini H, Saini A, Loeffler J, Ellenbogen KA, Koneru JN.

Pacing Clin Electrophysiol. 2019 Jun;42(6):739-742. doi: 10.1111/pace.13677. Epub 2019 Apr 9. No abstract available.


Treatment-Induced Brain Tissue Necrosis: A Clinical Challenge in Neuro-Oncology.

Winter SF, Loebel F, Loeffler J, Batchelor TT, Martinez-Lage M, Vajkoczy P, Dietrich J.

Neuro Oncol. 2019 Mar 4. pii: noz048. doi: 10.1093/neuonc/noz048. [Epub ahead of print]


Patterns of Failure Among Patients With Low-grade Glioma Treated With Proton Radiation Therapy.

Kamran SC, Dworkin M, Niemierko A, Bussiere M, Oh KS, Loeffler JS, Shih HA.

Pract Radiat Oncol. 2019 Feb 18. pii: S1879-8500(19)30049-9. doi: 10.1016/j.prro.2019.02.002. [Epub ahead of print]


Hypopituitarism After Cranial Irradiation for Meningiomas: A Single-Institution Experience.

Lamba N, Bussiere MR, Niemierko A, Abedi P, Fullerton BC, Loeffler JS, Oh KS, Nachtigall LB, Shih HA.

Pract Radiat Oncol. 2019 May;9(3):e266-e273. doi: 10.1016/j.prro.2019.01.009. Epub 2019 Feb 4.


Performance of a Hospital Pathway for Patients With a New Single Brain Mass.

Arrillaga-Romany I, Curry WT Jr, Jordan JT, Cahill DP, Nahed BV, Martuza RL, Loeffler JS, Järhult SJ, Muzikansky A, Cohen AB, Singhal AB, Goldstein JN, Batchelor TT.

J Oncol Pract. 2019 Mar;15(3):e211-e218. doi: 10.1200/JOP.17.00098. Epub 2019 Jan 25.


Comparative Analysis of Inflammatory Cytokine Release and Alveolar Epithelial Barrier Invasion in a Transwell® Bilayer Model of Mucormycosis.

Belic S, Page L, Lazariotou M, Waaga-Gasser AM, Dragan M, Springer J, Loeffler J, Morton CO, Einsele H, Ullmann AJ, Wurster S.

Front Microbiol. 2019 Jan 8;9:3204. doi: 10.3389/fmicb.2018.03204. eCollection 2018.


Characterizing the Diversity of the CDR-H3 Loop Conformational Ensembles in Relationship to Antibody Binding Properties.

Fernández-Quintero ML, Loeffler JR, Kraml J, Kahler U, Kamenik AS, Liedl KR.

Front Immunol. 2019 Jan 7;9:3065. doi: 10.3389/fimmu.2018.03065. eCollection 2018.


Interrelations Between Temporal and Spatial Cognition: The Role of Modality-Specific Processing.

Loeffler J, Cañal-Bruland R, Schroeger A, Tolentino-Castro JW, Raab M.

Front Psychol. 2018 Dec 21;9:2609. doi: 10.3389/fpsyg.2018.02609. eCollection 2018. Review.


Human NK cells adapt their immune response towards increasing multiplicities of infection of Aspergillus fumigatus.

Marischen L, Englert A, Schmitt AL, Einsele H, Loeffler J.

BMC Immunol. 2018 Dec 18;19(1):39. doi: 10.1186/s12865-018-0276-6.


Immunomodulation as a Therapy for Aspergillus Infection: Current Status and Future Perspectives.

Lauruschkat CD, Einsele H, Loeffler J.

J Fungi (Basel). 2018 Dec 14;4(4). pii: E137. doi: 10.3390/jof4040137. Review.


Long-term impact of a faculty mentoring program in academic medicine.

Efstathiou JA, Drumm MR, Paly JP, Lawton DM, O'Neill RM, Niemierko A, Leffert LR, Loeffler JS, Shih HA.

PLoS One. 2018 Nov 29;13(11):e0207634. doi: 10.1371/journal.pone.0207634. eCollection 2018.


Increase of pseudoprogression and other treatment related effects in low-grade glioma patients treated with proton radiation and temozolomide.

Dworkin M, Mehan W, Niemierko A, Kamran SC, Lamba N, Dietrich J, Martinez-Lage M, Oh KS, Batchelor TT, Wen PY, Loeffler JS, Shih HA.

J Neurooncol. 2019 Mar;142(1):69-77. doi: 10.1007/s11060-018-03063-1. Epub 2018 Nov 28.


Structural basis for the bi-functionality of human oxaloacetate decarboxylase FAHD1.

Weiss AKH, Naschberger A, Loeffler JR, Gstach H, Bowler MW, Holzknecht M, Cappuccio E, Pittl A, Etemad S, Dunzendorfer-Matt T, Scheffzek K, Liedl KR, Jansen-Dürr P.

Biochem J. 2018 Nov 20;475(22):3561-3576. doi: 10.1042/BCJ20180750.


Triacetylfusarinine C: A urine biomarker for diagnosis of invasive aspergillosis.

Hoenigl M, Orasch T, Faserl K, Prattes J, Loeffler J, Springer J, Gsaller F, Reischies F, Duettmann W, Raggam RB, Lindner H, Haas H.

J Infect. 2019 Feb;78(2):150-157. doi: 10.1016/j.jinf.2018.09.006. Epub 2018 Sep 26.


Correction to: Criteria for the definition of Pituitary Tumor Centers of Excellence (PTCOE): A Pituitary Society Statement.

Casanueva FF, Barkan AL, Buchfelder M, Klibanski A, Laws ER, Loeffler JS, Melmed S, Mortini P, Wass J, Giustina A; Pituitary Society, Expert Group on Pituitary Tumors.

Pituitary. 2018 Dec;21(6):663. doi: 10.1007/s11102-018-0912-4.


Validation of a simplified in vitro Transwell® model of the alveolar surface to assess host immunity induced by different morphotypes of Aspergillus fumigatus.

Morton CO, Wurster S, Fliesser M, Ebel F, Page L, Hünniger K, Kurzai O, Schmitt AL, Michel D, Springer J, Einsele H, Loeffler J.

Int J Med Microbiol. 2018 Dec;308(8):1009-1017. doi: 10.1016/j.ijmm.2018.09.001. Epub 2018 Sep 3.


First Insights in NK-DC Cross-Talk and the Importance of Soluble Factors During Infection With Aspergillus fumigatus.

Weiss E, Ziegler S, Fliesser M, Schmitt AL, Hünniger K, Kurzai O, Morton CO, Einsele H, Loeffler J.

Front Cell Infect Microbiol. 2018 Aug 20;8:288. doi: 10.3389/fcimb.2018.00288. eCollection 2018.


Comment on: T2Candida MR as a predictor of outcome in patients with suspected invasive candidiasis starting empirical antifungal treatment: a prospective pilot study.

White PL, Barnes RA, Gorton R, Cruciani M, Loeffler J; Fungal PCR Initiative (Working Group of the International Society of Human and Animal Mycology) .

J Antimicrob Chemother. 2019 Feb 1;74(2):532-533. doi: 10.1093/jac/dky325. No abstract available.


Proton Stereotactic Radiosurgery for Brain Metastases: A Single-Institution Analysis of 370 Patients.

Atkins KM, Pashtan IM, Bussière MR, Kang KH, Niemierko A, Daly JE, Botticello TM, Hurd MC, Chapman PH, Oh K, Loeffler JS, Shih HA.

Int J Radiat Oncol Biol Phys. 2018 Jul 15;101(4):820-829. doi: 10.1016/j.ijrobp.2018.03.056. Epub 2018 Apr 4.


Application of long single-stranded DNA donors in genome editing: generation and validation of mouse mutants.

Codner GF, Mianné J, Caulder A, Loeffler J, Fell R, King R, Allan AJ, Mackenzie M, Pike FJ, McCabe CV, Christou S, Joynson S, Hutchison M, Stewart ME, Kumar S, Simon MM, Agius L, Anstee QM, Volynski KE, Kullmann DM, Wells S, Teboul L.

BMC Biol. 2018 Jun 21;16(1):70. doi: 10.1186/s12915-018-0530-7.


C11 Methionine PET (MET-PET) Imaging of Glioblastoma for Detecting Postoperative Residual Disease and Response to Chemoradiation Therapy.

Wang Y, Rapalino O, Heidari P, Loeffler J, Shih HA, Oh K, Mahmood U.

Int J Radiat Oncol Biol Phys. 2018 Nov 15;102(4):1024-1028. doi: 10.1016/j.ijrobp.2018.06.011. Epub 2018 Jun 18.


Safety of combining radiotherapy with immune-checkpoint inhibition.

Hwang WL, Pike LRG, Royce TJ, Mahal BA, Loeffler JS.

Nat Rev Clin Oncol. 2018 Aug;15(8):477-494. doi: 10.1038/s41571-018-0046-7. Review.


"Radiobiology of Proton Therapy": Results of an international expert workshop.

Lühr A, von Neubeck C, Pawelke J, Seidlitz A, Peitzsch C, Bentzen SM, Bortfeld T, Debus J, Deutsch E, Langendijk JA, Loeffler JS, Mohan R, Scholz M, Sørensen BS, Weber DC, Baumann M, Krause M; “Radiobiology of Proton Therapy”.

Radiother Oncol. 2018 Jul;128(1):56-67. doi: 10.1016/j.radonc.2018.05.018. Epub 2018 Jun 1. Review.


The role of proton beam therapy in central neurocytoma: A single-institution experience.

Kang KH, Schapira E, Niemierko A, Martinez-Lage M, Bussière MR, Yock TI, Loeffler JS, Butler WE, Carter BS, Shih HA.

Pract Radiat Oncol. 2018 Sep - Oct;8(5):e305-e311. doi: 10.1016/j.prro.2018.02.005. Epub 2018 Feb 16.


The fumarylacetoacetate hydrolase (FAH) superfamily of enzymes: multifunctional enzymes from microbes to mitochondria.

Weiss AKH, Loeffler JR, Liedl KR, Gstach H, Jansen-Dürr P.

Biochem Soc Trans. 2018 Apr 17;46(2):295-309. doi: 10.1042/BST20170518. Epub 2018 Feb 27. Review.


Sphingolipid Metabolism Is Dysregulated at Transcriptomic and Metabolic Levels in the Spinal Cord of an Animal Model of Amyotrophic Lateral Sclerosis.

Henriques A, Croixmarie V, Bouscary A, Mosbach A, Keime C, Boursier-Neyret C, Walter B, Spedding M, Loeffler JP.

Front Mol Neurosci. 2018 Jan 4;10:433. doi: 10.3389/fnmol.2017.00433. eCollection 2017.


The Metabolic Microenvironment Steers Bone Tissue Regeneration.

Loeffler J, Duda GN, Sass FA, Dienelt A.

Trends Endocrinol Metab. 2018 Feb;29(2):99-110. doi: 10.1016/j.tem.2017.11.008. Epub 2017 Dec 28. Review.


Editorial: Charged Particles in Oncology.

Durante M, Cucinotta FA, Loeffler JS.

Front Oncol. 2017 Dec 8;7:301. doi: 10.3389/fonc.2017.00301. eCollection 2017. No abstract available.


Human and Murine Innate Immune Cell Populations Display Common and Distinct Response Patterns during Their In Vitro Interaction with the Pathogenic Mold Aspergillus fumigatus.

Hellmann AM, Lother J, Wurster S, Lutz MB, Schmitt AL, Morton CO, Eyrich M, Czakai K, Einsele H, Loeffler J.

Front Immunol. 2017 Dec 6;8:1716. doi: 10.3389/fimmu.2017.01716. eCollection 2017.


A Comparison of Aspergillus and Mucorales PCR Testing of Different Bronchoalveolar Lavage Fluid Fractions from Patients with Suspected Invasive Pulmonary Fungal Disease.

Springer J, White PL, Kessel J, Wieters I, Teschner D, Korczynski D, Liebregts T, Cornely OA, Schwartz S, Elgeti T, Meintker L, Krause SW, Posso RB, Heinz WJ, Fuhrmann S, Vehreschild JJ, Einsele H, Rickerts V, Loeffler J.

J Clin Microbiol. 2018 Jan 24;56(2). pii: e01655-17. doi: 10.1128/JCM.01655-17. Print 2018 Feb.


Walking Back to the Future.

Loeffler J, Raab M, Cañal-Bruland R.

Exp Psychol. 2017 Sep;64(5):346-358. doi: 10.1027/1618-3169/a000377.


NCCN Guidelines Insights: Central Nervous System Cancers, Version 1.2017.

Nabors LB, Portnow J, Ammirati M, Baehring J, Brem H, Butowski N, Fenstermaker RA, Forsyth P, Hattangadi-Gluth J, Holdhoff M, Howard S, Junck L, Kaley T, Kumthekar P, Loeffler JS, Moots PL, Mrugala MM, Nagpal S, Pandey M, Parney I, Peters K, Puduvalli VK, Ragsdale J, Rockhill J, Rogers L, Rusthoven C, Shonka N, Shrieve DC, Sills AK, Swinnen LJ, Tsien C, Weiss S, Wen PY, Willmarth N, Bergman MA, Engh A.

J Natl Compr Canc Netw. 2017 Nov;15(11):1331-1345. doi: 10.6004/jnccn.2017.0166.


The impact of different stereotactic radiation therapy regimens for brain metastases on local control and toxicity.

Jimenez RB, Alexander BM, Mahadevan A, Niemierko A, Rajakesari S, Arvold ND, Floyd SR, Oh KS, Loeffler JS, Shih HA.

Adv Radiat Oncol. 2017 Jun 6;2(3):391-397. doi: 10.1016/j.adro.2017.05.008. eCollection 2017 Jul-Sep.


Diagnosis of aspergillosis by PCR: Clinical considerations and technical tips.

Barnes RA, White PL, Morton CO, Rogers TR, Cruciani M, Loeffler J, Donnelly JP.

Med Mycol. 2018 Apr 1;56(suppl_1):60-72. doi: 10.1093/mmy/myx091. Review.


MicroRNA-378 enhances radiation response in ectopic and orthotopic implantation models of glioblastoma.

Li W, Liu Y, Yang W, Han X, Li S, Liu H, Gerweck LE, Fukumura D, Loeffler JS, Yang BB, Jain RK, Huang P.

J Neurooncol. 2018 Jan;136(1):63-71. doi: 10.1007/s11060-017-2646-y. Epub 2017 Oct 28.


Three ways to make proton therapy affordable.

Bortfeld TR, Loeffler JS.

Nature. 2017 Sep 25;549(7673):451-453. doi: 10.1038/549451a. No abstract available.


Criteria for the definition of Pituitary Tumor Centers of Excellence (PTCOE): A Pituitary Society Statement.

Casanueva FF, Barkan AL, Buchfelder M, Klibanski A, Laws ER, Loeffler JS, Melmed S, Mortini P, Wass J, Giustina A; Pituitary Society, Expert Group on Pituitary Tumors.

Pituitary. 2017 Oct;20(5):489-498. doi: 10.1007/s11102-017-0838-2. Erratum in: Pituitary. 2018 Sep 20;:.


Human primary myeloid dendritic cells interact with the opportunistic fungal pathogen Aspergillus fumigatus via the C-type lectin receptor Dectin-1.

Hefter M, Lother J, Weiß E, Schmitt AL, Fliesser M, Einsele H, Loeffler J.

Med Mycol. 2017 Jul 1;55(5):573-578. doi: 10.1093/mmy/myw105.


Prospective, Randomized Study of Radiation Dose Escalation With Combined Proton-Photon Therapy for Benign Meningiomas.

Sanford NN, Yeap BY, Larvie M, Daartz J, Munzenrider JE, Liebsch NJ, Fullerton B, Pan E, Loeffler JS, Shih HA.

Int J Radiat Oncol Biol Phys. 2017 Nov 15;99(4):787-796. doi: 10.1016/j.ijrobp.2017.07.008. Epub 2017 Jul 12.


CD56 Is a Pathogen Recognition Receptor on Human Natural Killer Cells.

Ziegler S, Weiss E, Schmitt AL, Schlegel J, Burgert A, Terpitz U, Sauer M, Moretta L, Sivori S, Leonhardt I, Kurzai O, Einsele H, Loeffler J.

Sci Rep. 2017 Jul 21;7(1):6138. doi: 10.1038/s41598-017-06238-4.


Inhibition of β-Glucocerebrosidase Activity Preserves Motor Unit Integrity in a Mouse Model of Amyotrophic Lateral Sclerosis.

Henriques A, Huebecker M, Blasco H, Keime C, Andres CR, Corcia P, Priestman DA, Platt FM, Spedding M, Loeffler JP.

Sci Rep. 2017 Jul 12;7(1):5235. doi: 10.1038/s41598-017-05313-0.


Histopathological prognostic factors of recurrence following definitive therapy for atypical and malignant meningiomas.

Kim D, Niemierko A, Hwang WL, Stemmer-Rachamimov AO, Curry WT, Barker FG, Martuza RL, Oh KS, Loeffler JS, Shih HA.

J Neurosurg. 2018 Apr;128(4):1123-1132. doi: 10.3171/2016.11.JNS16913. Epub 2017 Jun 16.


Autophagy in neuroinflammatory diseases.

Muller S, Brun S, René F, de Sèze J, Loeffler JP, Jeltsch-David H.

Autoimmun Rev. 2017 Aug;16(8):856-874. doi: 10.1016/j.autrev.2017.05.015. Epub 2017 May 29. Review.


Medical therapy and intervention do not improve uncomplicated isolated mesenteric artery dissection outcomes over observation alone.

Loeffler JW, Obara H, Fujimura N, Bove P, Newton DH, Zettervall SL, van Petersen AS, Geelkerken RH, Charlton-Ouw KM, Shalhub S, Singh N, Roussel A, Glebova NO, Harlander-Locke MP, Gasper WJ, Humphries MD, Lawrence PF.

J Vasc Surg. 2017 Jul;66(1):202-208. doi: 10.1016/j.jvs.2017.01.059. Epub 2017 May 12.


A prospective study of fungal biomarkers to improve management of invasive fungal diseases in a mixed specialty critical care unit.

Talento AF, Dunne K, Joyce EA, Palmer M, Johnson E, White PL, Springer J, Loeffler J, Ryan T, Collins D, Rogers TR.

J Crit Care. 2017 Aug;40:119-127. doi: 10.1016/j.jcrc.2017.03.025. Epub 2017 Mar 30.


Does movement influence representations of time and space?

Loeffler J, Raab M, Cañal-Bruland R.

PLoS One. 2017 Apr 4;12(4):e0175192. doi: 10.1371/journal.pone.0175192. eCollection 2017.

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