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Items: 1 to 50 of 143


Circulating Osteogenic Progenitor Cells in Mild, Moderate, and Severe Aortic Valve Stenosis.

Al-Hijji M, Narula N, Go JL, Khosla S, Enriquez-Sarano M, Loeffler D, Lennon R, Lerman LO, Lerman A.

Mayo Clin Proc. 2019 Apr;94(4):652-659. doi: 10.1016/j.mayocp.2019.01.005.


Influence of Normal Aging on Brain Autophagy: A Complex Scenario.

Loeffler DA.

Front Aging Neurosci. 2019 Mar 11;11:49. doi: 10.3389/fnagi.2019.00049. eCollection 2019. Review.


Linkage of the CF foundation patient registry with the pediatric health information system database.

Cogen JD, Hall M, Loeffler DR, Gove N, Onchiri F, Sawicki GS, Fink AK.

Pediatr Pulmonol. 2019 Jun;54(6):721-728. doi: 10.1002/ppul.24272. Epub 2019 Mar 18.


Understanding cell fate control by continuous single-cell quantification.

Loeffler D, Schroeder T.

Blood. 2019 Mar 28;133(13):1406-1414. doi: 10.1182/blood-2018-09-835397. Epub 2019 Feb 6. Review.


Development of Decreased-Gluten Wheat Enabled by Determination of the Genetic Basis of lys3a Barley.

Moehs CP, Austill WJ, Holm A, Large TAG, Loeffler D, Mullenberg J, Schnable PS, Skinner W, van Boxtel J, Wu L, McGuire C.

Plant Physiol. 2019 Apr;179(4):1692-1703. doi: 10.1104/pp.18.00771. Epub 2019 Jan 29.


Intraductal papillary mucinous neoplasm complicated by a gastropancreatic fistula.

Patel A, Allen A, Kuwahara J, Wadsworth T, Loeffler DM, Xie KL.

Radiol Case Rep. 2018 Dec 7;14(3):320-323. doi: 10.1016/j.radcr.2018.11.015. eCollection 2019 Mar.


Renal cell carcinoma presenting as epistaxis from a nasal cavity metastasis.

Allen A, Michals E, Karo A, Loeffler DM, Saran N.

Radiol Case Rep. 2018 Oct 26;14(1):116-120. doi: 10.1016/j.radcr.2018.10.009. eCollection 2019 Jan.


Local Production of Soluble Urokinase Plasminogen Activator Receptor and Plasminogen Activator Inhibitor-1 in the Coronary Circulation Is Associated With Coronary Endothelial Dysfunction in Humans.

Corban MT, Prasad A, Nesbitt L, Loeffler D, Herrmann J, Lerman LO, Lerman A.

J Am Heart Assoc. 2018 Aug 7;7(15):e009881. doi: 10.1161/JAHA.118.009881.


Inflammatory signals directly instruct PU.1 in HSCs via TNF.

Etzrodt M, Ahmed N, Hoppe PS, Loeffler D, Skylaki S, Hilsenbeck O, Kokkaliaris KD, Kaltenbach HM, Stelling J, Nerlov C, Schroeder T.

Blood. 2019 Feb 21;133(8):816-819. doi: 10.1182/blood-2018-02-832998. Epub 2018 Oct 9.


Rate and predictors of prescription of lumacaftor - Ivacaftor in the 18 months following approval in the United States.

Sawicki GS, Fink AK, Schechter MS, Loeffler DR, Mayer-Hamblett N.

J Cyst Fibros. 2018 Nov;17(6):742-746. doi: 10.1016/j.jcf.2018.08.007. Epub 2018 Sep 7.


Automated Microfluidic System for Dynamic Stimulation and Tracking of Single Cells.

Dettinger P, Frank T, Etzrodt M, Ahmed N, Reimann A, Trenzinger C, Loeffler D, Kokkaliaris KD, Schroeder T, Tay S.

Anal Chem. 2018 Sep 18;90(18):10695-10700. doi: 10.1021/acs.analchem.8b00312. Epub 2018 Jul 30.


Lineage marker synchrony in hematopoietic genealogies refutes the PU.1/GATA1 toggle switch paradigm.

Strasser MK, Hoppe PS, Loeffler D, Kokkaliaris KD, Schroeder T, Theis FJ, Marr C.

Nat Commun. 2018 Jul 12;9(1):2697. doi: 10.1038/s41467-018-05037-3.


Single-cell approaches identify the molecular network driving malignant hematopoietic stem cell self-renewal.

Shepherd MS, Li J, Wilson NK, Oedekoven CA, Li J, Belmonte M, Fink J, Prick JCM, Pask DC, Hamilton TL, Loeffler D, Rao A, Schröder T, Göttgens B, Green AR, Kent DG.

Blood. 2018 Aug 23;132(8):791-803. doi: 10.1182/blood-2017-12-821066. Epub 2018 Jul 10.


Cerebrospinal Fluid Concentration of Key Autophagy Protein Lamp2 Changes Little During Normal Aging.

Loeffler DA, Klaver AC, Coffey MP, Aasly JO.

Front Aging Neurosci. 2018 May 8;10:130. doi: 10.3389/fnagi.2018.00130. eCollection 2018.


Inductive and Selective Effects of GSK3 and MEK Inhibition on Nanog Heterogeneity in Embryonic Stem Cells.

Hastreiter S, Skylaki S, Loeffler D, Reimann A, Hilsenbeck O, Hoppe PS, Coutu DL, Kokkaliaris KD, Schwarzfischer M, Anastassiadis K, Theis FJ, Schroeder T.

Stem Cell Reports. 2018 Jul 10;11(1):58-69. doi: 10.1016/j.stemcr.2018.04.019. Epub 2018 May 17.


CSF lamp2 concentrations are decreased in female Parkinson's disease patients with LRRK2 mutations.

Klaver AC, Coffey MP, Aasly JO, Loeffler DA.

Brain Res. 2018 Mar 15;1683:12-16. doi: 10.1016/j.brainres.2018.01.016. Epub 2018 Feb 3.


Mouse and human HSPC immobilization in liquid culture by CD43- or CD44-antibody coating.

Loeffler D, Wang W, Hopf A, Hilsenbeck O, Bourgine PE, Rudolf F, Martin I, Schroeder T.

Blood. 2018 Mar 29;131(13):1425-1429. doi: 10.1182/blood-2017-07-794131. Epub 2018 Feb 16.


Dorsal thermal necrosis in dogs: a retrospective analysis of 16 cases in the southwestern USA (2009-2016).

Schwartz SL, Schick AE, Lewis TP, Loeffler D.

Vet Dermatol. 2018 Apr;29(2):139-e55. doi: 10.1111/vde.12519. Epub 2018 Feb 1.


Specific serum antibody binding to phosphorylated and non-phosphorylated tau in non-cognitively impaired, mildly cognitively impaired, and Alzheimer's disease subjects: an exploratory study.

Klaver AC, Coffey MP, Bennett DA, Loeffler DA.

Transl Neurodegener. 2017 Nov 24;6:32. doi: 10.1186/s40035-017-0100-x. eCollection 2017.


Polyvalent immunoglobulin binding is an obstacle to accurate measurement of specific antibodies with ELISA despite inclusion of blocking agents.

Loeffler DA, Klaver AC.

Int Immunopharmacol. 2017 Nov;52:227-229. doi: 10.1016/j.intimp.2017.09.016. Epub 2017 Sep 22.


Data that empower: The success and promise of CF patient registries.

Fink AK, Loeffler DR, Marshall BC, Goss CH, Morgan WJ.

Pediatr Pulmonol. 2017 Nov;52(S48):S44-S51. doi: 10.1002/ppul.23790. Epub 2017 Sep 14. Review.


Increased Oxidative Stress Markers in Cerebrospinal Fluid from Healthy Subjects with Parkinson's Disease-Associated LRRK2 Gene Mutations.

Loeffler DA, Klaver AC, Coffey MP, Aasly JO, LeWitt PA.

Front Aging Neurosci. 2017 Apr 3;9:89. doi: 10.3389/fnagi.2017.00089. eCollection 2017.


fastER: a user-friendly tool for ultrafast and robust cell segmentation in large-scale microscopy.

Hilsenbeck O, Schwarzfischer M, Loeffler D, Dimopoulos S, Hastreiter S, Marr C, Theis FJ, Schroeder T.

Bioinformatics. 2017 Jul 1;33(13):2020-2028. doi: 10.1093/bioinformatics/btx107.


Prospective identification of hematopoietic lineage choice by deep learning.

Buggenthin F, Buettner F, Hoppe PS, Endele M, Kroiss M, Strasser M, Schwarzfischer M, Loeffler D, Kokkaliaris KD, Hilsenbeck O, Schroeder T, Theis FJ, Marr C.

Nat Methods. 2017 Apr;14(4):403-406. doi: 10.1038/nmeth.4182. Epub 2017 Feb 20.


CSF-1-induced Src signaling can instruct monocytic lineage choice.

Endele M, Loeffler D, Kokkaliaris KD, Hilsenbeck O, Skylaki S, Hoppe PS, Schambach A, Stanley ER, Schroeder T.

Blood. 2017 Mar 23;129(12):1691-1701. doi: 10.1182/blood-2016-05-714329. Epub 2017 Feb 3.


Intramedullary amputation neuroma: a case report and review of the literature.

McGuire LS, Behbahini M, Das S, Loeffler D, Burger P, Engelhard H, Valyi-Nagy T, Mehta A.

Clin Neuropathol. 2017 Mar/Apr;36 (2017)(2):73-77. doi: 10.5414/NP300996. Review.


Circulating osteogenic endothelial progenitor cell counts: new biomarker for the severity of coronary artery disease.

Yang SW, Hennessy RR, Khosla S, Lennon R, Loeffler D, Sun T, Liu Z, Park KH, Wang FL, Lerman LO, Lerman A.

Int J Cardiol. 2017 Jan 15;227:833-839. doi: 10.1016/j.ijcard.2016.10.036. Epub 2016 Oct 27.


Solitary parotid metastasis 8 years after a nephrectomy for renal cell carcinoma.

Hussain F, Yedavalli N, Loeffler D, Kajdacsy-Balla A.

J Community Hosp Intern Med Perspect. 2016 Sep 7;6(4):31950. doi: 10.3402/jchimp.v6.31950. eCollection 2016.


Age-Related Decrease in Heat Shock 70-kDa Protein 8 in Cerebrospinal Fluid Is Associated with Increased Oxidative Stress.

Loeffler DA, Klaver AC, Coffey MP, Aasly JO, LeWitt PA.

Front Aging Neurosci. 2016 Jul 26;8:178. doi: 10.3389/fnagi.2016.00178. eCollection 2016.


The challenge of measuring intra-individual change in fatigue during cancer treatment.

Moinpour CM, Donaldson GW, Davis KM, Potosky AL, Jensen RE, Gralow JR, Back AL, Hwang JJ, Yoon J, Bernard DL, Loeffler DR, Rothrock NE, Hays RD, Reeve BB, Smith AW, Hahn EA, Cella D.

Qual Life Res. 2017 Feb;26(2):259-271. doi: 10.1007/s11136-016-1372-9. Epub 2016 Jul 28.


Early myeloid lineage choice is not initiated by random PU.1 to GATA1 protein ratios.

Hoppe PS, Schwarzfischer M, Loeffler D, Kokkaliaris KD, Hilsenbeck O, Moritz N, Endele M, Filipczyk A, Gambardella A, Ahmed N, Etzrodt M, Coutu DL, Rieger MA, Marr C, Strasser MK, Schauberger B, Burtscher I, Ermakova O, Bürger A, Lickert H, Nerlov C, Theis FJ, Schroeder T.

Nature. 2016 Jul 14;535(7611):299-302. doi: 10.1038/nature18320.


Nocardia asteroides-Induced movement abnormalities in mice: Relevance for Parkinson's disease?

Loeffler DA, LeWitt PA, Camp DM.

Mov Disord. 2016 Aug;31(8):1134-8. doi: 10.1002/mds.26711. Epub 2016 Jul 14. Review. No abstract available.


Software tools for single-cell tracking and quantification of cellular and molecular properties.

Hilsenbeck O, Schwarzfischer M, Skylaki S, Schauberger B, Hoppe PS, Loeffler D, Kokkaliaris KD, Hastreiter S, Skylaki E, Filipczyk A, Strasser M, Buggenthin F, Feigelman JS, Krumsiek J, van den Berg AJ, Endele M, Etzrodt M, Marr C, Theis FJ, Schroeder T.

Nat Biotechnol. 2016 Jul 12;34(7):703-6. doi: 10.1038/nbt.3626. No abstract available.


Identification of factors promoting ex vivo maintenance of mouse hematopoietic stem cells by long-term single-cell quantification.

Kokkaliaris KD, Drew E, Endele M, Loeffler D, Hoppe PS, Hilsenbeck O, Schauberger B, Hinzen C, Skylaki S, Theodorou M, Kieslinger M, Lemischka I, Moore K, Schroeder T.

Blood. 2016 Sep 1;128(9):1181-92. doi: 10.1182/blood-2016-03-705590. Epub 2016 Jun 30.


Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal.

Pietras EM, Mirantes-Barbeito C, Fong S, Loeffler D, Kovtonyuk LV, Zhang S, Lakshminarasimhan R, Chin CP, Techner JM, Will B, Nerlov C, Steidl U, Manz MG, Schroeder T, Passegué E.

Nat Cell Biol. 2016 Jun;18(6):607-18. doi: 10.1038/ncb3346. Epub 2016 Apr 25.


CSF Nrf2 and HSPA8 in Parkinson's disease patients with and without LRRK2 gene mutations.

Loeffler DA, Smith LM, Coffey MP, Aasly JO, LeWitt PA.

J Neural Transm (Vienna). 2016 Mar;123(3):179-87. doi: 10.1007/s00702-015-1479-0. Epub 2015 Nov 3.


Biophysical characterization data on Aβ soluble oligomers produced through a method enabling prolonged oligomer stability and biological buffer conditions.

Crisostomo AC, Dang L, Digambaranath JL, Klaver AC, Loeffler DA, Payne JJ, Smith LM, Yokom AL, Finke JM.

Data Brief. 2015 Aug 6;4:650-8. doi: 10.1016/j.dib.2015.07.034. eCollection 2015 Sep.


Network plasticity of pluripotency transcription factors in embryonic stem cells.

Filipczyk A, Marr C, Hastreiter S, Feigelman J, Schwarzfischer M, Hoppe PS, Loeffler D, Kokkaliaris KD, Endele M, Schauberger B, Hilsenbeck O, Skylaki S, Hasenauer J, Anastassiadis K, Theis FJ, Schroeder T.

Nat Cell Biol. 2015 Oct;17(10):1235-46. doi: 10.1038/ncb3237. Epub 2015 Sep 21.


ELISA measurement of specific antibodies to phosphorylated tau in intravenous immunoglobulin products.

Loeffler DA, Klaver AC, Coffey MP.

Int Immunopharmacol. 2015 Oct;28(2):1108-12. doi: 10.1016/j.intimp.2015.08.022. Epub 2015 Aug 30.


Inflammation-Induced Emergency Megakaryopoiesis Driven by Hematopoietic Stem Cell-like Megakaryocyte Progenitors.

Haas S, Hansson J, Klimmeck D, Loeffler D, Velten L, Uckelmann H, Wurzer S, Prendergast ÁM, Schnell A, Hexel K, Santarella-Mellwig R, Blaszkiewicz S, Kuck A, Geiger H, Milsom MD, Steinmetz LM, Schroeder T, Trumpp A, Krijgsveld J, Essers MA.

Cell Stem Cell. 2015 Oct 1;17(4):422-34. doi: 10.1016/j.stem.2015.07.007. Epub 2015 Aug 20.


Kinetic analysis of IgG antibodies to beta-amyloid oligomers with surface plasmon resonance.

Crisostomo AC, Dang L, Digambaranath JL, Klaver AC, Loeffler DA, Payne JJ, Smith LM, Yokom AL, Finke JM.

Anal Biochem. 2015 Jul 15;481:43-54. doi: 10.1016/j.ab.2015.03.032. Epub 2015 Apr 25.


Effects of antibodies to phosphorylated and non-phosphorylated tau on in vitro tau phosphorylation at Serine-199: Preliminary report.

Loeffler DA, Smith LM, Klaver AC, Martić S.

Exp Gerontol. 2015 Jul;67:15-8. doi: 10.1016/j.exger.2015.04.010. Epub 2015 Apr 22.


Erratum: Should development of Alzheimer's disease-specific intravenous immunoglobulin be considered?

Loeffler DA.

J Neuroinflammation. 2015 Apr 9;12:68. doi: 10.1186/s12974-015-0290-z. No abstract available.


Canine alopecia secondary to human topical hormone replacement therapy in six dogs.

Berger DJ, Lewis TP, Schick AE, Miller RI, Loeffler DG.

J Am Anim Hosp Assoc. 2015 Mar-Apr;51(2):136-42. doi: 10.5326/JAAHA-MS-6247. Epub 2015 Feb 19.


Effects of tau domain-specific antibodies and intravenous immunoglobulin on tau aggregation and aggregate degradation.

Esteves-Villanueva JO, Trzeciakiewicz H, Loeffler DA, Martić S.

Biochemistry. 2015 Jan 20;54(2):293-302. doi: 10.1021/bi501272x. Epub 2015 Jan 6.


Osteogenic monocytes within the coronary circulation and their association with plaque vulnerability in patients with early atherosclerosis.

Collin J, Gössl M, Matsuo Y, Cilluffo RR, Flammer AJ, Loeffler D, Lennon RJ, Simari RD, Spoon DB, Erbel R, Lerman LO, Khosla S, Lerman A.

Int J Cardiol. 2015 Feb 15;181:57-64. doi: 10.1016/j.ijcard.2014.11.156. Epub 2014 Nov 26.


Should development of Alzheimer's disease-specific intravenous immunoglobulin be considered?

Loeffler DA.

J Neuroinflammation. 2014 Dec 5;11:198. doi: 10.1186/s12974-014-0198-z. Review. Erratum in: J Neuroinflammation. 2015;12:68.


Aβ anti-idiotypic antibodies are present in intravenous immunoglobulin and are produced in mice following its administration.

Loeffler DA, Klaver AC, Coffey MP.

Autoimmunity. 2015 Jun;48(4):196-200. doi: 10.3109/08916934.2014.983265. Epub 2014 Nov 13.


Perinatal Immunization With Vaccine-Grade Listeria monocytogenes Provides Protection Against Murine Th2 Airway Inflammation.

Aloyouni SY, Segeritz CP, Sherrid AM, Gold MJ, Loeffler DI, Blanchet MR, Cai B, Hirota J, McNagny KM, Kollmann TR.

Allergy Asthma Immunol Res. 2014 Jul;6(4):341-9. doi: 10.4168/aair.2014.6.4.341. Epub 2014 Mar 21.


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