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Items: 1 to 50 of 67

1.

Amikacin Liposome Inhalation Suspension for Treatment-Refractory Lung Disease Caused by Mycobacterium avium Complex (CONVERT): A Prospective, Open-Label, Randomized Study.

Griffith DE, Eagle G, Thomson R, Aksamit TR, Hasegawa N, Morimoto K, Addrizzo-Harris DJ, O'Donnell AE, Marras TK, Flume PA, Loebinger MR, Morgan L, Codecasa LR, Hill AT, Ruoss SJ, Yim JJ, Ringshausen FC, Field SK, Philley JV, Wallace RJ Jr, van Ingen J, Coulter C, Nezamis J, Winthrop KL; CONVERT Study Group.

Am J Respir Crit Care Med. 2018 Sep 14. doi: 10.1164/rccm.201807-1318OC. [Epub ahead of print]

PMID:
30216086
2.

The cost of Mycobacterium avium complex lung disease in Canada, France, Germany, and the United Kingdom: a nationally representative observational study.

Goring SM, Wilson JB, Risebrough NR, Gallagher J, Carroll S, Heap KJ, Obradovic M, Loebinger MR, Diel R.

BMC Health Serv Res. 2018 Sep 10;18(1):700. doi: 10.1186/s12913-018-3489-8.

3.

Latent class analysis to define radiological subgroups in pulmonary nontuberculous mycobacterial disease.

Cowman SA, Jacob J, Obaidee S, Andres Floto R, Wilson R, Haworth CS, Loebinger MR.

BMC Pulm Med. 2018 Aug 31;18(1):145. doi: 10.1186/s12890-018-0675-8.

4.

Risk factors for situs defects and congenital heart disease in primary ciliary dyskinesia.

Best S, Shoemark A, Rubbo B, Patel MP, Fassad MR, Dixon M, Rogers AV, Hirst RA, Rutman A, Ollosson S, Jackson CL, Goggin P, Thomas S, Pengelly R, Cullup T, Pissaridou E, Hayward J, Onoufriadis A, O'Callaghan C, Loebinger MR, Wilson R, Chung EM, Kenia P, Doughty VL, Carvalho JS, Lucas JS, Mitchison HM, Hogg C.

Thorax. 2018 Aug 30. pii: thoraxjnl-2018-212104. doi: 10.1136/thoraxjnl-2018-212104. [Epub ahead of print]

PMID:
30166424
5.

The Italian registry of pulmonary non-tuberculous mycobacteria - IRENE: the study protocol.

Aliberti S, Codecasa LR, Gori A, Sotgiu G, Spotti M, Di Biagio A, Calcagno A, Nardini S, Assael BM, Tortoli E, Besozzi G, Ferrarese M, Matteelli A, Girardi E, De Lorenzo S, Seia M, Gramegna A, Del Prato B, Terranova L, Oriano M, Sverzellati N, Mirsaeidi M, Chalmers JD, Haworth CS, Loebinger MR, Aksamit T, Winthrop K, Ringshausen FC, Previdi G, Blasi F; IRENE Network.

Multidiscip Respir Med. 2018 Aug 9;13(Suppl 1):33. doi: 10.1186/s40248-018-0141-8. eCollection 2018.

6.

Diagnosis of Nontuberculous Mycobacteria Lung Disease.

Cowman SA, Loebinger MR.

Semin Respir Crit Care Med. 2018 Jun;39(3):343-350. doi: 10.1055/s-0038-1651493. Epub 2018 Aug 2.

PMID:
30071549
7.

Lung function in patients with primary ciliary dyskinesia: an iPCD Cohort study.

Halbeisen FS, Goutaki M, Spycher BD, Amirav I, Behan L, Boon M, Hogg C, Casaulta C, Crowley S, Haarman EG, Karadag B, Koerner-Rettberg C, Loebinger MR, Mazurek H, Morgan L, Nielsen KG, Omran H, Santamaria F, Schwerk N, Thouvenin G, Yiallouros P, Lucas JS, Latzin P, Kuehni CE.

Eur Respir J. 2018 Aug 23;52(2). pii: 1801040. doi: 10.1183/13993003.01040-2018. Print 2018 Aug.

PMID:
30049738
8.

The utility of drug reaction assessment trials for inhaled therapies in patients with chronic lung diseases.

Dennis BB, Rinaldi G, Housley G, Shah A, Shah OA, Loebinger MR.

Respir Med. 2018 Jul;140:122-126. doi: 10.1016/j.rmed.2018.06.008. Epub 2018 Jun 8.

PMID:
29957273
9.

Reply to: Reduced IFN-γ in Patients with Pulmonary Nontuberculous Mycobacterial Disease: Potentially Multiple Causes.

Cowman SA, Loebinger MR.

Am J Respir Cell Mol Biol. 2018 Jul;59(1):131. doi: 10.1165/rcmb.2018-0032LE. No abstract available.

PMID:
29957047
10.

The impact of acute air pollution fluctuations on bronchiectasis pulmonary exacerbation: a case-crossover analysis.

Goeminne PC, Cox B, Finch S, Loebinger MR, Bedi P, Hill AT, Fardon TC, de Hoogh K, Nawrot TS, Chalmers JD.

Eur Respir J. 2018 Jul 27;52(1). pii: 1702557. doi: 10.1183/13993003.02557-2017. Print 2018 Jul.

PMID:
29903857
11.

Primary ciliary dyskinesia with normal ultrastructure: three-dimensional tomography detects absence of DNAH11.

Shoemark A, Burgoyne T, Kwan R, Dixon M, Patel MP, Rogers AV, Onoufriadis A, Scully J, Daudvohra F, Cullup T, Loebinger MR, Wilson R, Chung EMK, Bush A, Mitchison HM, Hogg C.

Eur Respir J. 2018 Feb 21;51(2). pii: 1701809. doi: 10.1183/13993003.01809-2017. Print 2018 Feb.

PMID:
29467202
12.

British Thoracic Society Guideline for the management of non-tuberculous mycobacterial pulmonary disease (NTM-PD).

Haworth CS, Banks J, Capstick T, Fisher AJ, Gorsuch T, Laurenson IF, Leitch A, Loebinger MR, Milburn HJ, Nightingale M, Ormerod P, Shingadia D, Smith D, Whitehead N, Wilson R, Floto RA.

BMJ Open Respir Res. 2017 Oct 19;4(1):e000242. doi: 10.1136/bmjresp-2017-000242. eCollection 2017. Review.

13.

Primary Ciliary Dyskinesia Due to Microtubular Defects is Associated with Worse Lung Clearance Index.

Irving S, Dixon M, Fassad MR, Frost E, Hayward J, Kilpin K, Ollosson S, Onoufriadis A, Patel MP, Scully J, Carr SB, Mitchison HM, Loebinger MR, Hogg C, Shoemark A, Bush A.

Lung. 2018 Apr;196(2):231-238. doi: 10.1007/s00408-018-0086-x. Epub 2018 Jan 24.

14.

Growth and nutritional status, and their association with lung function: a study from the international Primary Ciliary Dyskinesia Cohort.

Goutaki M, Halbeisen FS, Spycher BD, Maurer E, Belle F, Amirav I, Behan L, Boon M, Carr S, Casaulta C, Clement A, Crowley S, Dell S, Ferkol T, Haarman EG, Karadag B, Knowles M, Koerner-Rettberg C, Leigh MW, Loebinger MR, Mazurek H, Morgan L, Nielsen KG, Phillipsen M, Sagel SD, Santamaria F, Schwerk N, Yiallouros P, Lucas JS, Kuehni CE; PCD Israeli Consortium; Swiss PCD Group; French Reference Centre for Rare Lung Diseases.

Eur Respir J. 2017 Dec 21;50(6). pii: 1701659. doi: 10.1183/13993003.01659-2017. Print 2017 Dec.

PMID:
29269581
15.

The BRICS (Bronchiectasis Radiologically Indexed CT Score): A Multicenter Study Score for Use in Idiopathic and Postinfective Bronchiectasis.

Bedi P, Chalmers JD, Goeminne PC, Mai C, Saravanamuthu P, Velu PP, Cartlidge MK, Loebinger MR, Jacob J, Kamal F, Schembri N, Aliberti S, Hill U, Harrison M, Johnson C, Screaton N, Haworth C, Polverino E, Rosales E, Torres A, Benegas MN, Rossi AG, Patel D, Hill AT.

Chest. 2018 May;153(5):1177-1186. doi: 10.1016/j.chest.2017.11.033. Epub 2017 Dec 13.

PMID:
29247616
16.

Whole-Blood Gene Expression in Pulmonary Nontuberculous Mycobacterial Infection.

Cowman SA, Jacob J, Hansell DM, Kelleher P, Wilson R, Cookson WOC, Moffatt MF, Loebinger MR.

Am J Respir Cell Mol Biol. 2018 Apr;58(4):510-518. doi: 10.1165/rcmb.2017-0230OC.

17.

British Thoracic Society guidelines for the management of non-tuberculous mycobacterial pulmonary disease (NTM-PD).

Haworth CS, Banks J, Capstick T, Fisher AJ, Gorsuch T, Laurenson IF, Leitch A, Loebinger MR, Milburn HJ, Nightingale M, Ormerod P, Shingadia D, Smith D, Whitehead N, Wilson R, Floto RA.

Thorax. 2017 Nov;72(Suppl 2):ii1-ii64. doi: 10.1136/thoraxjnl-2017-210927. Review. No abstract available.

PMID:
29054853
18.

Pulmonary disease by non-tuberculous mycobacteria - clinical management, unmet needs and future perspectives.

Larsson LO, Polverino E, Hoefsloot W, Codecasa LR, Diel R, Jenkins SG, Loebinger MR.

Expert Rev Respir Med. 2017 Dec;11(12):977-989. doi: 10.1080/17476348.2017.1386563. Epub 2017 Oct 10. Review.

PMID:
28967797
19.

Mycobacterium avium complex infection: phenotypes and outcomes.

Loebinger MR.

Eur Respir J. 2017 Sep 27;50(3). pii: 1701380. doi: 10.1183/13993003.01380-2017. Print 2017 Sep. No abstract available.

PMID:
28954776
20.

The European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC): experiences from a successful ERS Clinical Research Collaboration.

Chalmers JD, Crichton M, Goeminne PC, Loebinger MR, Haworth C, Almagro M, Vendrell M, De Soyza A, Dhar R, Morgan L, Blasi F, Aliberti S, Boyd J, Polverino E.

Breathe (Sheff). 2017 Sep;13(3):180-192. doi: 10.1183/20734735.005117. Review.

21.

European Respiratory Society guidelines for the management of adult bronchiectasis.

Polverino E, Goeminne PC, McDonnell MJ, Aliberti S, Marshall SE, Loebinger MR, Murris M, Cantón R, Torres A, Dimakou K, De Soyza A, Hill AT, Haworth CS, Vendrell M, Ringshausen FC, Subotic D, Wilson R, Vilaró J, Stallberg B, Welte T, Rohde G, Blasi F, Elborn S, Almagro M, Timothy A, Ruddy T, Tonia T, Rigau D, Chalmers JD.

Eur Respir J. 2017 Sep 9;50(3). pii: 1700629. doi: 10.1183/13993003.00629-2017. Print 2017 Sep.

PMID:
28889110
22.

High prevalence of CCDC103 p.His154Pro mutation causing primary ciliary dyskinesia disrupts protein oligomerisation and is associated with normal diagnostic investigations.

Shoemark A, Moya E, Hirst RA, Patel MP, Robson EA, Hayward J, Scully J, Fassad MR, Lamb W, Schmidts M, Dixon M, Patel-King RS, Rogers AV, Rutman A, Jackson CL, Goggin P, Rubbo B, Ollosson S, Carr S, Walker W, Adler B, Loebinger MR, Wilson R, Bush A, Williams H, Boustred C, Jenkins L, Sheridan E, Chung EMK, Watson CM, Cullup T, Lucas JS, Kenia P, O'Callaghan C, King SM, Hogg C, Mitchison HM.

Thorax. 2018 Feb;73(2):157-166. doi: 10.1136/thoraxjnl-2017-209999. Epub 2017 Aug 8.

PMID:
28790179
23.

The Objective Assessment of Cough Frequency in Bronchiectasis.

Spinou A, Lee KK, Sinha A, Elston C, Loebinger MR, Wilson R, Chung KF, Yousaf N, Pavord ID, Matos S, Garrod R, Birring SS.

Lung. 2017 Oct;195(5):575-585. doi: 10.1007/s00408-017-0038-x. Epub 2017 Jul 13.

24.

Pulmonary exacerbation in adults with bronchiectasis: a consensus definition for clinical research.

Hill AT, Haworth CS, Aliberti S, Barker A, Blasi F, Boersma W, Chalmers JD, De Soyza A, Dimakou K, Elborn JS, Feldman C, Flume P, Goeminne PC, Loebinger MR, Menendez R, Morgan L, Murris M, Polverino E, Quittner A, Ringshausen FC, Tino G, Torres A, Vendrell M, Welte T, Wilson R, Wong C, O'Donnell A, Aksamit T; EMBARC/BRR definitions working group.

Eur Respir J. 2017 Jun 8;49(6). pii: 1700051. doi: 10.1183/13993003.00051-2017. Print 2017 Jun.

PMID:
28596426
25.

The development and validation of the Bronchiectasis Health Questionnaire.

Spinou A, Siegert RJ, Guan WJ, Patel AS, Gosker HR, Lee KK, Elston C, Loebinger MR, Wilson R, Garrod R, Birring SS.

Eur Respir J. 2017 May 11;49(5). pii: 1601532. doi: 10.1183/13993003.01532-2016. Print 2017 May.

26.

A lesson in plasticity: a 74-year-old man with plastic bronchitis.

Shah A, Donovan J, Marino P, Shah PL, Devaraj A, Wechalekar K, Maher TM, Loebinger MR, Wilson R.

Thorax. 2017 Nov;72(11):1055-1057. doi: 10.1136/thoraxjnl-2017-209965. Epub 2017 Apr 3. No abstract available.

27.

Scoliosis convexity and organ anatomy are related.

Schlösser TPC, Semple T, Carr SB, Padley S, Loebinger MR, Hogg C, Castelein RM.

Eur Spine J. 2017 Jun;26(6):1595-1599. doi: 10.1007/s00586-017-4970-5. Epub 2017 Feb 8.

PMID:
28180983
28.

X-linked primary ciliary dyskinesia due to mutations in the cytoplasmic axonemal dynein assembly factor PIH1D3.

Olcese C, Patel MP, Shoemark A, Kiviluoto S, Legendre M, Williams HJ, Vaughan CK, Hayward J, Goldenberg A, Emes RD, Munye MM, Dyer L, Cahill T, Bevillard J, Gehrig C, Guipponi M, Chantot S, Duquesnoy P, Thomas L, Jeanson L, Copin B, Tamalet A, Thauvin-Robinet C, Papon JF, Garin A, Pin I, Vera G, Aurora P, Fassad MR, Jenkins L, Boustred C, Cullup T, Dixon M, Onoufriadis A, Bush A, Chung EM, Antonarakis SE, Loebinger MR, Wilson R, Armengot M, Escudier E, Hogg C; UK10K Rare Group, Amselem S, Sun Z, Bartoloni L, Blouin JL, Mitchison HM.

Nat Commun. 2017 Feb 8;8:14279. doi: 10.1038/ncomms14279.

29.

Longitudinal assessment of sputum microbiome by sequencing of the 16S rRNA gene in non-cystic fibrosis bronchiectasis patients.

Cox MJ, Turek EM, Hennessy C, Mirza GK, James PL, Coleman M, Jones A, Wilson R, Bilton D, Cookson WO, Moffatt MF, Loebinger MR.

PLoS One. 2017 Feb 7;12(2):e0170622. doi: 10.1371/journal.pone.0170622. eCollection 2017.

30.

The international primary ciliary dyskinesia cohort (iPCD Cohort): methods and first results.

Goutaki M, Maurer E, Halbeisen FS, Amirav I, Barbato A, Behan L, Boon M, Casaulta C, Clement A, Crowley S, Haarman E, Hogg C, Karadag B, Koerner-Rettberg C, Leigh MW, Loebinger MR, Mazurek H, Morgan L, Nielsen KG, Omran H, Schwerk N, Scigliano S, Werner C, Yiallouros P, Zivkovic Z, Lucas JS, Kuehni CE; PCD Italian Consortium; Swiss PCD Group; French Reference Centre for Rare Lung Diseases; Genetic Disorders of Mucociliary Clearance Consortium.

Eur Respir J. 2017 Jan 4;49(1). pii: 1601181. doi: 10.1183/13993003.01181-2016. Print 2017 Jan.

31.

Comorbidities and the risk of mortality in patients with bronchiectasis: an international multicentre cohort study.

McDonnell MJ, Aliberti S, Goeminne PC, Restrepo MI, Finch S, Pesci A, Dupont LJ, Fardon TC, Wilson R, Loebinger MR, Skrbic D, Obradovic D, De Soyza A, Ward C, Laffey JG, Rutherford RM, Chalmers JD.

Lancet Respir Med. 2016 Dec;4(12):969-979. doi: 10.1016/S2213-2600(16)30320-4. Epub 2016 Nov 16.

32.

Characterizing Non-Tuberculous Mycobacteria Infection in Bronchiectasis.

Faverio P, Stainer A, Bonaiti G, Zucchetti SC, Simonetta E, Lapadula G, Marruchella A, Gori A, Blasi F, Codecasa L, Pesci A, Chalmers JD, Loebinger MR, Aliberti S.

Int J Mol Sci. 2016 Nov 16;17(11). pii: E1913.

33.

Long-term antibiotic treatment for non-cystic fibrosis bronchiectasis in adults: evidence, current practice and future use.

Goldman N, Loebinger MR, Wilson R.

Expert Rev Respir Med. 2016 Dec;10(12):1259-1268. Epub 2016 Nov 21.

PMID:
27820964
34.

Bronchiectasis in yellow nail syndrome.

Woodfield G, Nisbet M, Jacob J, Mok W, Loebinger MR, Hansell DM, Wells AU, Wilson R.

Respirology. 2017 Jan;22(1):101-107. doi: 10.1111/resp.12866. Epub 2016 Aug 23.

35.

Multidimensional severity assessment in bronchiectasis: an analysis of seven European cohorts.

McDonnell MJ, Aliberti S, Goeminne PC, Dimakou K, Zucchetti SC, Davidson J, Ward C, Laffey JG, Finch S, Pesci A, Dupont LJ, Fardon TC, Skrbic D, Obradovic D, Cowman S, Loebinger MR, Rutherford RM, De Soyza A, Chalmers JD.

Thorax. 2016 Dec;71(12):1110-1118. doi: 10.1136/thoraxjnl-2016-208481. Epub 2016 Aug 11.

36.

A longitudinal study characterising a large adult primary ciliary dyskinesia population.

Shah A, Shoemark A, MacNeill SJ, Bhaludin B, Rogers A, Bilton D, Hansell DM, Wilson R, Loebinger MR.

Eur Respir J. 2016 Aug;48(2):441-50. doi: 10.1183/13993003.00209-2016. Epub 2016 Jun 10.

37.

Research priorities in bronchiectasis: a consensus statement from the EMBARC Clinical Research Collaboration.

Aliberti S, Masefield S, Polverino E, De Soyza A, Loebinger MR, Menendez R, Ringshausen FC, Vendrell M, Powell P, Chalmers JD; EMBARC Study Group.

Eur Respir J. 2016 Sep;48(3):632-47. doi: 10.1183/13993003.01888-2015. Epub 2016 Jun 10.

38.

Hyperthermia treatment of tumors by mesenchymal stem cell-delivered superparamagnetic iron oxide nanoparticles.

Kalber TL, Ordidge KL, Southern P, Loebinger MR, Kyrtatos PG, Pankhurst QA, Lythgoe MF, Janes SM.

Int J Nanomedicine. 2016 May 9;11:1973-83. doi: 10.2147/IJN.S94255. eCollection 2016.

39.

The validity of health-related quality of life questionnaires in bronchiectasis: a systematic review and meta-analysis.

Spinou A, Fragkos KC, Lee KK, Elston C, Siegert RJ, Loebinger MR, Wilson R, Garrod R, Birring SS.

Thorax. 2016 Aug;71(8):683-94. doi: 10.1136/thoraxjnl-2015-207315. Epub 2016 Feb 11. Review.

PMID:
26869589
40.

The antimicrobial susceptibility of non-tuberculous mycobacteria.

Cowman S, Burns K, Benson S, Wilson R, Loebinger MR.

J Infect. 2016 Mar;72(3):324-31. doi: 10.1016/j.jinf.2015.12.007. Epub 2015 Dec 24.

PMID:
26723913
41.

Predicting mortality in bronchiectasis using bronchiectasis severity index and FACED scores: a 19-year cohort study.

Ellis HC, Cowman S, Fernandes M, Wilson R, Loebinger MR.

Eur Respir J. 2016 Feb;47(2):482-9. doi: 10.1183/13993003.01312-2015. Epub 2015 Nov 19.

42.

The reproducibility and responsiveness of the lung clearance index in bronchiectasis.

Grillo L, Irving S, Hansell DM, Nair A, Annan B, Ward S, Bilton D, Main E, Davies J, Bush A, Wilson R, Loebinger MR.

Eur Respir J. 2015 Dec;46(6):1645-53. doi: 10.1183/13993003.00152-2015. Epub 2015 Sep 4.

43.

Screening for latent tuberculosis before tumour necrosis factor antagonist therapy.

Loebinger MR, Pozniak A.

Eur Respir J. 2015 May;45(5):1512-3. doi: 10.1183/09031936.00020315. No abstract available.

44.

Chronic Infection by Mucoid Pseudomonas aeruginosa Associated with Dysregulation in T-Cell Immunity to Outer Membrane Porin F.

Quigley KJ, Reynolds CJ, Goudet A, Raynsford EJ, Sergeant R, Quigley A, Worgall S, Bilton D, Wilson R, Loebinger MR, Maillere B, Altmann DM, Boyton RJ.

Am J Respir Crit Care Med. 2015 Jun 1;191(11):1250-64. doi: 10.1164/rccm.201411-1995OC.

45.

Non-cystic fibrosis bronchiectasis: an evidence-base for new therapies.

Bilton D, Loebinger MR, Wilson R.

Lancet Respir Med. 2014 Dec;2(12):958-60. doi: 10.1016/S2213-2600(14)70274-7. Epub 2014 Nov 19. No abstract available.

PMID:
25466345
46.

An evaluation of the use of a negative interferon-γ release assay for tuberculosis screening before TNF antagonist therapy.

Woodfield G, Passey-Heaton B, Chakrabarti A, Pozniak A, Loebinger MR.

Eur Respir J. 2014 Nov;44(5):1369-72. doi: 10.1183/09031936.00125714. Epub 2014 Sep 3. No abstract available.

47.

Evidence of mycobacterial disease in COPD patients with lung volume reduction surgery; the importance of histological assessment of specimens: a cohort study.

Char A, Hopkinson NS, Hansell DM, Nicholson AG, Shaw EC, Clark SJ, Sedgwick P, Wilson R, Jordan S, Loebinger MR.

BMC Pulm Med. 2014 Aug 2;14:124. doi: 10.1186/1471-2466-14-124.

48.

Mycobacterium avium complex infection in non-cystic fibrosis bronchiectasis.

Zoumot Z, Boutou AK, Gill SS, van Zeller M, Hansell DM, Wells AU, Wilson R, Loebinger MR.

Respirology. 2014 Jul;19(5):714-22. doi: 10.1111/resp.12287. Epub 2014 Apr 1.

49.

BIIL 284 reduces neutrophil numbers but increases P. aeruginosa bacteremia and inflammation in mouse lungs.

Döring G, Bragonzi A, Paroni M, Aktürk FF, Cigana C, Schmidt A, Gilpin D, Heyder S, Born T, Smaczny C, Kohlhäufl M, Wagner TO, Loebinger MR, Bilton D, Tunney MM, Elborn JS, Pier GB, Konstan MW, Ulrich M.

J Cyst Fibros. 2014 Mar;13(2):156-63. doi: 10.1016/j.jcf.2013.10.007. Epub 2013 Oct 31.

50.

Cyclical caspofungin for chronic pulmonary aspergillosis in sarcoidosis.

Keir GJ, Garfield B, Hansell DM, Loebinger MR, Wilson R, Renzoni EA, Wells AU, Maher TM.

Thorax. 2014 Mar;69(3):287-8. doi: 10.1136/thoraxjnl-2013-203988. Epub 2013 Sep 12.

PMID:
24029745

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