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Items: 1 to 20 of 253

1.

Tissue-specific pathways extrude activated ILC2s to disseminate type 2 immunity.

Ricardo-Gonzalez RR, Schneider C, Liao C, Lee J, Liang HE, Locksley RM.

J Exp Med. 2020 Apr 6;217(4). pii: e20191172. doi: 10.1084/jem.20191172.

PMID:
32031571
2.

Differences in the chitinolytic activity of mammalian chitinases on soluble and insoluble substrates.

Barad BA, Liu L, Diaz RE, Basilio R, Van Dyken SJ, Locksley RM, Fraser JS.

Protein Sci. 2020 Jan 12. doi: 10.1002/pro.3822. [Epub ahead of print]

PMID:
31930591
3.

Tissue immunity broadcasts near and far.

Molofsky AB, Locksley RM.

Nat Rev Immunol. 2020 Feb;20(2):93-94. doi: 10.1038/s41577-019-0250-4. No abstract available.

PMID:
31748703
4.

Production of IFNβ by Conventional Dendritic Cells after Stimulation with Viral Compounds and IFNβ-Independent IFNAR1-Signaling Pathways are Associated with Aggravation of Polymicrobial Sepsis.

Howe M, Bauer J, Schulze A, Kropp S, Locksley RM, Alferink J, Weighardt H, Scheu S.

Int J Mol Sci. 2019 Sep 7;20(18). pii: E4410. doi: 10.3390/ijms20184410.

5.

Making Asthma Crystal Clear.

Fahy JV, Locksley RM.

N Engl J Med. 2019 Aug 29;381(9):882-884. doi: 10.1056/NEJMcibr1908064. No abstract available.

PMID:
31461600
6.

ILC2s chew the fat.

Ricardo-Gonzalez RR, Locksley RM.

J Exp Med. 2019 Sep 2;216(9):1972-1973. doi: 10.1084/jem.20191098. Epub 2019 Aug 12.

PMID:
31405894
7.

Tissue-Resident Group 2 Innate Lymphoid Cells Differentiate by Layered Ontogeny and In Situ Perinatal Priming.

Schneider C, Lee J, Koga S, Ricardo-Gonzalez RR, Nussbaum JC, Smith LK, Villeda SA, Liang HE, Locksley RM.

Immunity. 2019 Jun 18;50(6):1425-1438.e5. doi: 10.1016/j.immuni.2019.04.019. Epub 2019 May 22.

PMID:
31128962
8.

Regulation of immune responses by tuft cells.

Schneider C, O'Leary CE, Locksley RM.

Nat Rev Immunol. 2019 Sep;19(9):584-593. doi: 10.1038/s41577-019-0176-x. Review.

PMID:
31114038
9.

Tuft Cells-Systemically Dispersed Sensory Epithelia Integrating Immune and Neural Circuitry.

O'Leary CE, Schneider C, Locksley RM.

Annu Rev Immunol. 2019 Apr 26;37:47-72. doi: 10.1146/annurev-immunol-042718-041505. Epub 2018 Oct 31.

PMID:
30379593
10.

Tissue signals imprint ILC2 identity with anticipatory function.

Ricardo-Gonzalez RR, Van Dyken SJ, Schneider C, Lee J, Nussbaum JC, Liang HE, Vaka D, Eckalbar WL, Molofsky AB, Erle DJ, Locksley RM.

Nat Immunol. 2018 Oct;19(10):1093-1099. doi: 10.1038/s41590-018-0201-4. Epub 2018 Sep 10.

11.

Innate Lymphoid Cells: 10 Years On.

Vivier E, Artis D, Colonna M, Diefenbach A, Di Santo JP, Eberl G, Koyasu S, Locksley RM, McKenzie ANJ, Mebius RE, Powrie F, Spits H.

Cell. 2018 Aug 23;174(5):1054-1066. doi: 10.1016/j.cell.2018.07.017. Review.

12.

Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development.

Miller CN, Proekt I, von Moltke J, Wells KL, Rajpurkar AR, Wang H, Rattay K, Khan IS, Metzger TC, Pollack JL, Fries AC, Lwin WW, Wigton EJ, Parent AV, Kyewski B, Erle DJ, Hogquist KA, Steinmetz LM, Locksley RM, Anderson MS.

Nature. 2018 Jul;559(7715):627-631. doi: 10.1038/s41586-018-0345-2. Epub 2018 Jul 18.

13.

Detection of Succinate by Intestinal Tuft Cells Triggers a Type 2 Innate Immune Circuit.

Nadjsombati MS, McGinty JW, Lyons-Cohen MR, Jaffe JB, DiPeso L, Schneider C, Miller CN, Pollack JL, Nagana Gowda GA, Fontana MF, Erle DJ, Anderson MS, Locksley RM, Raftery D, von Moltke J.

Immunity. 2018 Jul 17;49(1):33-41.e7. doi: 10.1016/j.immuni.2018.06.016.

14.

Publisher Correction: Parasitic helminths induce fetal-like reversion in the intestinal stem cell niche.

Nusse YM, Savage AK, Marangoni P, Rosendahl-Huber AKM, Landman TA, de Sauvage FJ, Locksley RM, Klein OD.

Nature. 2018 Oct;562(7727):E22. doi: 10.1038/s41586-018-0370-1.

PMID:
30013120
15.

Chitins and chitinase activity in airway diseases.

Van Dyken SJ, Locksley RM.

J Allergy Clin Immunol. 2018 Aug;142(2):364-369. doi: 10.1016/j.jaci.2018.06.017. Epub 2018 Jun 28. Review.

16.

Parasitic helminths induce fetal-like reversion in the intestinal stem cell niche.

Nusse YM, Savage AK, Marangoni P, Rosendahl-Huber AKM, Landman TA, de Sauvage FJ, Locksley RM, Klein OD.

Nature. 2018 Jul;559(7712):109-113. doi: 10.1038/s41586-018-0257-1. Epub 2018 Jun 27. Erratum in: Nature. 2018 Oct;562(7727):E22.

17.

Why Innate Lymphoid Cells?

Kotas ME, Locksley RM.

Immunity. 2018 Jun 19;48(6):1081-1090. doi: 10.1016/j.immuni.2018.06.002. Review.

18.

A Metabolite-Triggered Tuft Cell-ILC2 Circuit Drives Small Intestinal Remodeling.

Schneider C, O'Leary CE, von Moltke J, Liang HE, Ang QY, Turnbaugh PJ, Radhakrishnan S, Pellizzon M, Ma A, Locksley RM.

Cell. 2018 Jul 12;174(2):271-284.e14. doi: 10.1016/j.cell.2018.05.014. Epub 2018 Jun 7.

19.

Pulmonary neuroendocrine cells amplify allergic asthma responses.

Sui P, Wiesner DL, Xu J, Zhang Y, Lee J, Van Dyken S, Lashua A, Yu C, Klein BS, Locksley RM, Deutsch G, Sun X.

Science. 2018 Jun 8;360(6393). pii: eaan8546. doi: 10.1126/science.aan8546. Epub 2018 Mar 29.

20.

Perinatal Licensing of Thermogenesis by IL-33 and ST2.

Odegaard JI, Lee MW, Sogawa Y, Bertholet AM, Locksley RM, Weinberg DE, Kirichok Y, Deo RC, Chawla A.

Cell. 2017 Dec 14;171(7):1707. doi: 10.1016/j.cell.2017.12.003. No abstract available.

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