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Items: 1 to 50 of 175

1.

Do cholesterol and sphingomyelin change the mechanism of Aβ25-35 peptide binding to zwitterionic bilayer?

Smith AK, Khayat E, Lockhart C, Klimov DK.

J Chem Inf Model. 2019 Nov 18. doi: 10.1021/acs.jcim.9b00763. [Epub ahead of print]

PMID:
31738555
2.

Determinants of ferritin response to oral iron supplementation in children with sleep movement disorders.

DelRosso LM, Yi T, Chan JHM, Wrede JE, Lockhart CT, Ferri R.

Sleep. 2019 Sep 29. pii: zsz234. doi: 10.1093/sleep/zsz234. [Epub ahead of print]

PMID:
31563958
3.

Comorbidities in children with elevated periodic limb movement index during sleep.

DelRosso LM, Lockhart C, Wrede JE, Chen ML, Samson M, Reed J, Martin-Washo S, Arp M, Ferri R.

Sleep. 2019 Sep 26. pii: zsz221. doi: 10.1093/sleep/zsz221. [Epub ahead of print]

PMID:
31555831
4.

32 year follow up of patients following atrial redirection surgery for transposition of the great arteries.

Morrison ML, Grant B, McCrossan BA, Sands AJ, Owens CG, Spence MS, Casey FA, Craig BG, Lockhart CJ.

Congenit Heart Dis. 2019 Sep;14(5):846-853. doi: 10.1111/chd.12822. Epub 2019 Sep 6.

PMID:
31489769
5.

Technology to Assist Aging in Place: The Perspective of Health Organizations.

Hunter I, Elers P, Lockhart C, Whiddett D, Guesgen H, Singh A.

Stud Health Technol Inform. 2019 Aug 21;264:1688-1689. doi: 10.3233/SHTI190598.

PMID:
31438294
6.

Descriptive Analysis of Long- and Intermediate-Acting Insulin and Key Safety Outcomes in Adults with Type 2 Diabetes Mellitus.

Kent DJ, McMahill-Walraven CN, Panozzo CA, Pawloski PA, Haynes K, Marshall J, Brown J, Eichelberger B, Lockhart CM.

J Manag Care Spec Pharm. 2019 Nov;25(11):1162-1171. doi: 10.18553/jmcp.2019.19042. Epub 2019 Aug 12.

7.

Barriers and facilitators to conduct high-quality, large-scale safety and comparative effectiveness research: The Biologics and Biosimilars Collective Intelligence Consortium experience.

Lockhart CM, McDermott CL, Felix T, Lin ND, Cziraky MJ, Mendelsohn AB, Brown JS.

Pharmacoepidemiol Drug Saf. 2019 Aug 11. doi: 10.1002/pds.4885. [Epub ahead of print] No abstract available.

PMID:
31402533
8.

Harnessing the Biologics and Biosimilars Collective Intelligence Consortium to Evaluate Patterns of Care.

McMahill-Walraven CN, Kent DJ, Panozzo CA, Pawloski PA, Haynes K, Marshall J, Brown J, Eichelberger B, Lockhart CM.

J Manag Care Spec Pharm. 2019 Nov;25(11):1156-1161. doi: 10.18553/jmcp.2019.19041. Epub 2019 Aug 9.

9.

Methodologic considerations for noninterventional studies of switching from reference biologic to biosimilars.

Desai RJ, Kim SC, Curtis JR, Bosco JLF, Eichelberger B, Barr CE, Lockhart CM, Bradbury BD, Clewell J, Cohen HP, Gagne JJ; Biologics and Biosimilars Collective Intelligence Consortium (BBCIC) Switching Workgroup.

Pharmacoepidemiol Drug Saf. 2019 Jul 12. doi: 10.1002/pds.4809. [Epub ahead of print] Review.

PMID:
31298463
10.

Methionine Oxidation Changes the Mechanism of Aβ Peptide Binding to the DMPC Bilayer.

Lockhart C, Smith AK, Klimov DK.

Sci Rep. 2019 Apr 11;9(1):5947. doi: 10.1038/s41598-019-42304-9.

11.

Predictive Models to Determine Clinically Relevant Deviations in Delivered Dose for Head and Neck Cancer.

McCulloch MM, Lee C, Rosen BS, Kamp JD, Lockhart CM, Lee JY, Polan DF, Hawkins PG, Anderson CJR, Heukelom J, Sonke JJ, Fuller CD, Balter JM, Ten Haken RK, Eisbruch A, Brock KK.

Pract Radiat Oncol. 2019 Jul - Aug;9(4):e422-e431. doi: 10.1016/j.prro.2019.02.014. Epub 2019 Mar 2.

PMID:
30836190
12.

Acute Effects of Interset Rest Duration on Physiological and Perceptual Responses to Resistance Exercise in Hypoxia.

Lockhart C, Scott BR, Thoseby B, Dascombe BJ.

J Strength Cond Res. 2018 Jul 30. doi: 10.1519/JSC.0000000000002755. [Epub ahead of print]

PMID:
30063554
13.

Early Changes in Serial CBCT-Measured Parotid Gland Biomarkers Predict Chronic Xerostomia After Head and Neck Radiation Therapy.

Rosen BS, Hawkins PG, Polan DF, Balter JM, Brock KK, Kamp JD, Lockhart CM, Eisbruch A, Mierzwa ML, Ten Haken RK, El Naqa I.

Int J Radiat Oncol Biol Phys. 2018 Nov 15;102(4):1319-1329. doi: 10.1016/j.ijrobp.2018.06.048. Epub 2018 Jul 10.

14.

User Requirements for Technology to Assist Aging in Place: Qualitative Study of Older People and Their Informal Support Networks.

Elers P, Hunter I, Whiddett D, Lockhart C, Guesgen H, Singh A.

JMIR Mhealth Uhealth. 2018 Jun 6;6(6):e10741. doi: 10.2196/10741.

15.
16.

Intelligent Digital Environment for Wellbeing and Health.

Hunter I, Lockhart C, Elers P, Whiddett D, Guesgen H.

Stud Health Technol Inform. 2017;245:1229.

PMID:
29295316
17.

Intracameral ketorolac concentration at the beginning and end of cataract surgery following preoperative topical ketorolac administration.

Katsev DA, Katsev CC, Pinnow J, Lockhart CM.

Clin Ophthalmol. 2017 Oct 24;11:1897-1901. doi: 10.2147/OPTH.S149523. eCollection 2017.

18.

Cholesterol Changes the Mechanisms of Aβ Peptide Binding to the DMPC Bilayer.

Lockhart C, Klimov DK.

J Chem Inf Model. 2017 Oct 23;57(10):2554-2565. doi: 10.1021/acs.jcim.7b00431. Epub 2017 Oct 2.

PMID:
28910085
19.

Longitudinal characterisation of function and structure of Bietti crystalline dystrophy: report on a novel homozygous mutation in CYP4V2.

Lockhart CM, Smith TB, Yang P, Naidu M, Rettie AE, Nath A, Weleber R, Kelly EJ.

Br J Ophthalmol. 2018 Feb;102(2):187-194. doi: 10.1136/bjophthalmol-2016-309696. Epub 2017 Jul 11.

20.

Congenital Bilateral C2 Transverse Foramina Stenosis Causing Adult-Onset Vertebrobasilar Insufficiency and Posterior Circulation Stroke.

Gordhan A, Lockhart C.

Case Rep Neurol. 2017 May 17;9(2):137-142. doi: 10.1159/000476031. eCollection 2017 May-Aug.

21.

Is the Conformational Ensemble of Alzheimer's Aβ10-40 Peptide Force Field Dependent?

Siwy CM, Lockhart C, Klimov DK.

PLoS Comput Biol. 2017 Jan 13;13(1):e1005314. doi: 10.1371/journal.pcbi.1005314. eCollection 2017 Jan.

22.

Acute Physiological Responses to Moderate-Load Resistance Exercise in Hypoxia.

Scott BR, Slattery KM, Sculley DV, Lockhart C, Dascombe BJ.

J Strength Cond Res. 2017 Jul;31(7):1973-1981. doi: 10.1519/JSC.0000000000001649.

PMID:
27662491
23.

Does Replica Exchange with Solute Tempering Efficiently Sample Aβ Peptide Conformational Ensembles?

Smith AK, Lockhart C, Klimov DK.

J Chem Theory Comput. 2016 Oct 11;12(10):5201-5214. Epub 2016 Sep 6.

PMID:
27560127
24.

Contemporary imaging following atrial redirection surgery for transposition of the great arteries.

Morrison ML, Lockhart CJ, Grant B.

Heart. 2016 Oct 1;102(19):1551. doi: 10.1136/heartjnl-2016-309602. Epub 2016 Jun 10.

PMID:
27288280
25.

Clinical T2N0 Esophageal Cancer: Identifying Pretreatment Characteristics Associated With Pathologic Upstaging and the Potential Role for Induction Therapy.

Samson P, Puri V, Robinson C, Lockhart C, Carpenter D, Broderick S, Kreisel D, Krupnick AS, Patterson GA, Meyers B, Crabtree T.

Ann Thorac Surg. 2016 Jun;101(6):2102-11. doi: 10.1016/j.athoracsur.2016.01.033. Epub 2016 Apr 12.

26.

The Alzheimer's disease Aβ peptide binds to the anionic DMPS lipid bilayer.

Lockhart C, Klimov DK.

Biochim Biophys Acta. 2016 Jun;1858(6):1118-28. doi: 10.1016/j.bbamem.2016.03.001. Epub 2016 Mar 4.

27.

A Phase I Trial of BKM120 (Buparlisib) in Combination with Fulvestrant in Postmenopausal Women with Estrogen Receptor-Positive Metastatic Breast Cancer.

Ma CX, Luo J, Naughton M, Ademuyiwa F, Suresh R, Griffith M, Griffith OL, Skidmore ZL, Spies NC, Ramu A, Trani L, Pluard T, Nagaraj G, Thomas S, Guo Z, Hoog J, Han J, Mardis E, Lockhart C, Ellis MJ.

Clin Cancer Res. 2016 Apr 1;22(7):1583-91. doi: 10.1158/1078-0432.CCR-15-1745. Epub 2015 Nov 12.

28.

Greedy replica exchange algorithm for heterogeneous computing grids.

Lockhart C, O'Connor J, Armentrout S, Klimov DK.

J Mol Model. 2015 Sep;21(9):243. doi: 10.1007/s00894-015-2763-5. Epub 2015 Aug 27.

PMID:
26311229
29.

Hydrogen bond donation to the heme distal ligand of Staphylococcus aureus IsdG tunes the electronic structure.

Lockhart CL, Conger MA, Pittman DS, Liptak MD.

J Biol Inorg Chem. 2015 Jul;20(5):757-70. doi: 10.1007/s00775-015-1263-5. Epub 2015 Apr 25.

PMID:
25911498
30.

Calcium enhances binding of Aβ monomer to DMPC lipid bilayer.

Lockhart C, Klimov DK.

Biophys J. 2015 Apr 7;108(7):1807-1818. doi: 10.1016/j.bpj.2015.03.001.

31.

Classical eye signs in bacterial endocarditis.

Loughrey PB, Armstrong D, Lockhart CJ.

QJM. 2015 Nov;108(11):909-10. doi: 10.1093/qjmed/hcv055. Epub 2015 Mar 11. No abstract available.

PMID:
25762500
32.

Outcomes of Hybrid Video Assisted Thoracoscopic Surgery for Pulmonary Metastasectomy.

Raza A, Takabe K, Wolfe LG, Lockhart CG, Kim RH.

J Surg Sci. 2014 Dec;2(1):18-24.

33.

Using exceedance probabilities to detect anomalies in routinely recorded animal health data, with particular reference to foot-and-mouth disease in Viet Nam.

Richards KK, Hazelton ML, Stevenson MA, Lockhart CY, Pinto J, Nguyen L.

Spat Spatiotemporal Epidemiol. 2014 Oct;11:125-33. doi: 10.1016/j.sste.2014.08.002. Epub 2014 Sep 28.

PMID:
25457601
34.

Multimodal functional and anatomic imaging identifies preclinical microvascular abnormalities in type 1 diabetes mellitus.

Lockhart CJ, McCann AJ, Pinnock RA, Hamilton PK, Harbinson MT, McVeigh GE.

Am J Physiol Heart Circ Physiol. 2014 Dec 15;307(12):H1729-36. doi: 10.1152/ajpheart.00372.2014. Epub 2014 Oct 3.

35.

Generation and characterization of a murine model of Bietti crystalline dystrophy.

Lockhart CM, Nakano M, Rettie AE, Kelly EJ.

Invest Ophthalmol Vis Sci. 2014 Aug 12;55(9):5572-81. doi: 10.1167/iovs.13-13717.

36.

Binding of Aβ peptide creates lipid density depression in DMPC bilayer.

Lockhart C, Klimov DK.

Biochim Biophys Acta. 2014 Oct;1838(10):2678-88. doi: 10.1016/j.bbamem.2014.07.010. Epub 2014 Jul 15.

37.

Sedentary behavior and sleep efficiency in active community-dwelling older adults.

Madden KM, Ashe MC, Lockhart C, Chase JM.

Sleep Sci. 2014 Jun;7(2):82-8. doi: 10.1016/j.slsci.2014.09.009. Epub 2014 Sep 16.

38.

Ocular cytochrome P450s and transporters: roles in disease and endobiotic and xenobiotic disposition.

Nakano M, Lockhart CM, Kelly EJ, Rettie AE.

Drug Metab Rev. 2014 Aug;46(3):247-60. doi: 10.3109/03602532.2014.921190. Epub 2014 May 26. Review.

39.

Accelerometer-based measures of sedentary behavior and cardio-metabolic risk in active older adults.

Chase JM, Lockhart CK, Ashe MC, Madden KM.

Clin Invest Med. 2014 Apr 1;37(2):E108-16.

PMID:
24690418
40.

Alzheimer's Aβ10-40 peptide binds and penetrates DMPC bilayer: an isobaric-isothermal replica exchange molecular dynamics study.

Lockhart C, Klimov DK.

J Phys Chem B. 2014 Mar 13;118(10):2638-48. doi: 10.1021/jp412153s. Epub 2014 Feb 28.

PMID:
24547901
41.

Aerobic training in older adults with type 2 diabetes and vasodepressive carotid sinus hypersensitivity.

Madden KM, Lockhart C, Cuff D, Potter TF, Meneilly GS.

Aging Clin Exp Res. 2013 Dec;25(6):651-7. doi: 10.1007/s40520-013-0160-4. Epub 2013 Oct 22.

PMID:
24146363
42.

Revealing hidden helix propensity in Aβ peptides by molecular dynamics simulations.

Lockhart C, Klimov DK.

J Phys Chem B. 2013 Oct 10;117(40):12030-8. doi: 10.1021/jp407705j. Epub 2013 Sep 25.

PMID:
24016319
43.

Experience using the new GORE Septal Occluder at the margins.

Lockhart CJ, Johnston NG, Spence MS.

Catheter Cardiovasc Interv. 2013 Jun 1;81(7):1244-8. doi: 10.1002/ccd.24736. Epub 2013 Feb 27.

PMID:
23418128
44.

Molecular interactions of Alzheimer's biomarker FDDNP with Aβ peptide.

Lockhart C, Klimov DK.

Biophys J. 2012 Dec 5;103(11):2341-51. doi: 10.1016/j.bpj.2012.10.003.

45.

Synthesis and structural characterization of a family of modified hafnium tert-butoxide for use as precursors to hafnia nanoparticles.

Boyle TJ, Steele LA, Burton PD, Hoppe SM, Lockhart C, Rodriguez MA.

Inorg Chem. 2012 Nov 19;51(22):12075-92. doi: 10.1021/ic300622h. Epub 2012 Nov 6.

PMID:
23131086
46.

Explicit solvent molecular dynamics simulations of Aβ peptide interacting with ibuprofen ligands.

Lockhart C, Kim S, Klimov DK.

J Phys Chem B. 2012 Nov 1;116(43):12922-32. doi: 10.1021/jp306208n. Epub 2012 Oct 18.

PMID:
23051147
47.

Aerobic training-induced improvements in arterial stiffness are not sustained in older adults with multiple cardiovascular risk factors.

Madden KM, Lockhart C, Cuff D, Potter TF, Meneilly GS.

J Hum Hypertens. 2013 May;27(5):335-9. doi: 10.1038/jhh.2012.38. Epub 2012 Sep 6.

48.

Mammaglobin-A cDNA vaccination of breast cancer patients induces antigen-specific cytotoxic CD4+ICOShi T cells.

Tiriveedhi V, Fleming TP, Goedegebuure PS, Naughton M, Ma C, Lockhart C, Gao F, Gillanders WE, Mohanakumar T.

Breast Cancer Res Treat. 2013 Feb;138(1):109-18. doi: 10.1007/s10549-012-2110-9. Epub 2012 Jun 8.

49.

Short-term efficacy of palliative balloon aortic valvuloplasty in selected patients with high operative risk.

Daly MJ, Monaghan M, Hamilton A, Lockhart C, Kodoth V, Pillai S, Manoharan G, Spence MS.

J Invasive Cardiol. 2012 Feb;24(2):58-62.

50.

Outcomes of a hybrid technique for video-assisted thoracoscopic surgery (VATS) pulmonary resection in a community setting.

Kim RH, Takabe K, Lockhart CG.

J Thorac Dis. 2010 Dec;2(4):210-4. doi: 10.3978/j.issn.2072-1439.2010.11.5.

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