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Items: 26

1.

HDAC inhibition does not induce estrogen receptor in human triple-negative breast cancer cell lines and patient-derived xenografts.

de Cremoux P, Dalvai M, N'Doye O, Moutahir F, Rolland G, Chouchane-Mlik O, Assayag F, Lehmann-Che J, Kraus-Berthie L, Nicolas A, Lockhart BP, Marangoni E, de Thé H, Depil S, Bystricky K, Decaudin D.

Breast Cancer Res Treat. 2015 Jan;149(1):81-9. doi: 10.1007/s10549-014-3233-y. Epub 2014 Dec 12.

PMID:
25503779
2.

S49076 is a novel kinase inhibitor of MET, AXL, and FGFR with strong preclinical activity alone and in association with bevacizumab.

Burbridge MF, Bossard CJ, Saunier C, Fejes I, Bruno A, Léonce S, Ferry G, Da Violante G, Bouzom F, Cattan V, Jacquet-Bescond A, Comoglio PM, Lockhart BP, Boutin JA, Cordi A, Ortuno JC, Pierré A, Hickman JA, Cruzalegui FH, Depil S.

Mol Cancer Ther. 2013 Sep;12(9):1749-62. doi: 10.1158/1535-7163.MCT-13-0075. Epub 2013 Jun 26.

3.

Applying systems biology in drug discovery and development.

Galizzi JP, Lockhart BP, Bril A.

Drug Metabol Drug Interact. 2013;28(2):67-78. doi: 10.1515/dmdi-2013-0002. Review.

PMID:
23612649
4.

Genetic deletion of trace amine 1 receptors reveals their role in auto-inhibiting the actions of ecstasy (MDMA).

Di Cara B, Maggio R, Aloisi G, Rivet JM, Lundius EG, Yoshitake T, Svenningsson P, Brocco M, Gobert A, De Groote L, Cistarelli L, Veiga S, De Montrion C, Rodriguez M, Galizzi JP, Lockhart BP, Cogé F, Boutin JA, Vayer P, Verdouw PM, Groenink L, Millan MJ.

J Neurosci. 2011 Nov 23;31(47):16928-40. doi: 10.1523/JNEUROSCI.2502-11.2011.

5.

Molecular characterization of the AMPA-receptor potentiator S70340 in rat primary cortical culture: whole-genome expression profiling.

Mourlevat S, Galizzi JP, Guigal-Stéphan N, Courtade-Gaïani S, Rolland-Valognes G, Rodriguez M, Barbet F, Bourrier C, Catesson S, Chomel A, Danober L, Villain N, Caignard DH, Pirotte B, Lestage P, Lockhart BP.

Neurosci Res. 2011 Aug;70(4):349-60. doi: 10.1016/j.neures.2011.05.004. Epub 2011 May 14.

PMID:
21609738
6.

Neuropilin-1 is upregulated in hepatocellular carcinoma and contributes to tumour growth and vascular remodelling.

Bergé M, Allanic D, Bonnin P, de Montrion C, Richard J, Suc M, Boivin JF, Contrerès JO, Lockhart BP, Pocard M, Lévy BI, Tucker GC, Tobelem G, Merkulova-Rainon T.

J Hepatol. 2011 Oct;55(4):866-75. doi: 10.1016/j.jhep.2011.01.033. Epub 2011 Feb 19.

PMID:
21338642
7.

Coordinate Transcriptomic and Metabolomic Effects of the Insulin Sensitizer Rosiglitazone on Fundamental Metabolic Pathways in Liver, Soleus Muscle, and Adipose Tissue in Diabetic db/db Mice.

Le Bouter S, Rodriguez M, Guigal-Stephan N, Courtade-Gaïani S, Xuereb L, de Montrion C, Croixmarie V, Umbdenstock T, Boursier-Neyret C, Lonchampt M, Brun M, Dacquet C, Ktorza A, Lockhart BP, Galizzi JP.

PPAR Res. 2010;2010. pii: 679184. doi: 10.1155/2010/679184. Epub 2010 Oct 10.

8.

Only a subset of Met-activated pathways are required to sustain oncogene addiction.

Bertotti A, Burbridge MF, Gastaldi S, Galimi F, Torti D, Medico E, Giordano S, Corso S, Rolland-Valognes G, Lockhart BP, Hickman JA, Comoglio PM, Trusolino L.

Sci Signal. 2009;2(102):er11.

PMID:
20039471
9.

Only a subset of Met-activated pathways are required to sustain oncogene addiction.

Bertotti A, Burbridge MF, Gastaldi S, Galimi F, Torti D, Medico E, Giordano S, Corso S, Rolland-Valognes G, Lockhart BP, Hickman JA, Comoglio PM, Trusolino L.

Sci Signal. 2009 Dec 8;2(100):ra80. doi: 10.1126/scisignal.2000643. Erratum in: Sci Signal. 2009 Dec 22;2(102):er11. Corrected and republished in: Sci Signal. 2009;2(102):er11.

10.

Nox4 mediates the expression of plasminogen activator inhibitor-1 via p38 MAPK pathway in cultured human endothelial cells.

Jaulmes A, Sansilvestri-Morel P, Rolland-Valognes G, Bernhardt F, Gaertner R, Lockhart BP, Cordi A, Wierzbicki M, Rupin A, Verbeuren TJ.

Thromb Res. 2009 Sep;124(4):439-46. doi: 10.1016/j.thromres.2009.05.018. Epub 2009 Jun 21.

PMID:
19540572
11.

[Biomarkers: "Found in translation"].

Lockhart BP, Walther B.

Med Sci (Paris). 2009 Apr;25(4):423-30. doi: 10.1051/medsci/2009254423. Review. French.

12.

S18986: a positive modulator of AMPA-receptors enhances (S)-AMPA-mediated BDNF mRNA and protein expression in rat primary cortical neuronal cultures.

Lockhart BP, Rodriguez M, Mourlevat S, Peron P, Catesson S, Villain N, Galizzi JP, Boutin JA, Lestage P.

Eur J Pharmacol. 2007 Apr 30;561(1-3):23-31. Epub 2007 Feb 1.

PMID:
17331496
13.

Cognition enhancing or neuroprotective compounds for the treatment of cognitive disorders: why? when? which?

Lockhart BP, Lestage PJ.

Exp Gerontol. 2003 Jan-Feb;38(1-2):119-28. Review.

PMID:
12543269
14.

Suppression of nitric oxide formation by tyrosine kinase inhibitors in murine N9 microglia.

Lockhart BP, Cressey KC, Lepagnol JM.

Br J Pharmacol. 1998 Mar;123(5):879-89.

15.

Neuroprotective and anti-amnesic potentials of sigma (sigma) receptor ligands.

Maurice T, Lockhart BP.

Prog Neuropsychopharmacol Biol Psychiatry. 1997 Jan;21(1):69-102. Review.

PMID:
9075259
16.

Reversion of beta 25-35-amyloid peptide-induced amnesia by NMDA receptor-associated glycine site agonists.

Maurice T, Lockhart BP, Su TP, Privat A.

Brain Res. 1996 Aug 26;731(1-2):249-53.

PMID:
8883881
17.

Amnesia induced in mice by centrally administered beta-amyloid peptides involves cholinergic dysfunction.

Maurice T, Lockhart BP, Privat A.

Brain Res. 1996 Jan 15;706(2):181-93.

PMID:
8822355
18.

The epidermolytic (exfoliative) toxins of Staphylococcus aureus.

Bailey CJ, Lockhart BP, Redpath MB, Smith TP.

Med Microbiol Immunol. 1995 Aug;184(2):53-61. Review.

PMID:
7500911
19.
20.

A N-methyl-D-aspartate receptor-mediated neurotoxic effect of aspartate-based hydroxamate compounds in rat primary neuronal cultures.

Lockhart BP, Hamedi-Sangsari F, Vignon J, Privat A, Vila J.

Brain Res. 1995 Jan 30;670(2):313-6.

PMID:
7743196
21.
22.
23.

ELISA estimation of the binding of epidermolytic toxin to neonatal mouse skin.

Lockhart BP, Bailey CJ.

Toxicon. 1993 May;31(5):569-76.

PMID:
8332989
24.

Inhibition of rabies virus transcription in rat cortical neurons with the dissociative anesthetic ketamine.

Lockhart BP, Tordo N, Tsiang H.

Antimicrob Agents Chemother. 1992 Aug;36(8):1750-5.

25.

Actin-independent maturation of rabies virus in neuronal cultures.

Lockhart BP, Tsiang H.

J Gen Virol. 1991 Sep;72 ( Pt 9):2257-61.

PMID:
1895064
26.

Immunofluorescence localization of the epidermolytic toxin target in mouse epidermal cells and tissue.

Lockhart BP, Smith TP, Bailey CJ.

Histochem J. 1991 Sep;23(9):385-91.

PMID:
1720767

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