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Items: 1 to 50 of 59

1.

Inducible nitric oxide synthase-derived extracellular nitric oxide flux regulates proinflammatory responses at the single cell level.

Somasundaram V, Gilmore AC, Basudhar D, Palmieri EM, Scheiblin DA, Heinz WF, Cheng RYS, Ridnour LA, Altan-Bonnet G, Lockett SJ, McVicar DW, Wink DA.

Redox Biol. 2020 Jan;28:101354. doi: 10.1016/j.redox.2019.101354. Epub 2019 Nov 1.

2.

The Natural Product Butylcycloheptyl Prodiginine Binds Pre-miR-21, Inhibits Dicer-Mediated Processing of Pre-miR-21, and Blocks Cellular Proliferation.

Matarlo JS, Krumpe LRH, Heinz WF, Oh D, Shenoy SR, Thomas CL, Goncharova EI, Lockett SJ, O'Keefe BR.

Cell Chem Biol. 2019 Aug 15;26(8):1133-1142.e4. doi: 10.1016/j.chembiol.2019.04.011. Epub 2019 May 30.

PMID:
31155509
3.

Photoinducible Oncometabolite Detection.

Kulkarni RA, Briney CA, Crooks DR, Bergholtz SE, Mushti C, Lockett SJ, Lane AN, Fan TW, Swenson RE, Marston Linehan W, Meier JL.

Chembiochem. 2019 Feb 1;20(3):360-365. doi: 10.1002/cbic.201800651. Epub 2018 Dec 13.

PMID:
30358041
4.

Understanding the tumour micro-environment communication network from an NOS2/COX2 perspective.

Basudhar D, Bharadwaj G, Somasundaram V, Cheng RYS, Ridnour LA, Fujita M, Lockett SJ, Anderson SK, McVicar DW, Wink DA.

Br J Pharmacol. 2019 Jan;176(2):155-176. doi: 10.1111/bph.14488. Epub 2018 Nov 6. Review.

PMID:
30152521
5.

Coexpression of NOS2 and COX2 accelerates tumor growth and reduces survival in estrogen receptor-negative breast cancer.

Basudhar D, Glynn SA, Greer M, Somasundaram V, No JH, Scheiblin DA, Garrido P, Heinz WF, Ryan AE, Weiss JM, Cheng RYS, Ridnour LA, Lockett SJ, McVicar DW, Ambs S, Wink DA.

Proc Natl Acad Sci U S A. 2017 Dec 5;114(49):13030-13035. doi: 10.1073/pnas.1709119114. Epub 2017 Oct 27.

6.

pH Alkalinization by Chloroquine Suppresses Pathogenic Burkholderia Type 6 Secretion System 1 and Multinucleated Giant Cells.

Chua J, Senft JL, Lockett SJ, Brett PJ, Burtnick MN, DeShazer D, Friedlander AM.

Infect Immun. 2016 Dec 29;85(1). pii: e00586-16. doi: 10.1128/IAI.00586-16. Print 2017 Jan.

7.

Cytoskeletal abnormalities and neutrophil dysfunction in WDR1 deficiency.

Kuhns DB, Fink DL, Choi U, Sweeney C, Lau K, Priel DL, Riva D, Mendez L, Uzel G, Freeman AF, Olivier KN, Anderson VL, Currens R, Mackley V, Kang A, Al-Adeli M, Mace E, Orange JS, Kang E, Lockett SJ, Chen, Steinbach PJ, Hsu AP, Zarember KA, Malech HL, Gallin JI, Holland SM.

Blood. 2016 Oct 27;128(17):2135-2143. Epub 2016 Aug 24.

8.

Speeding up image cytometry.

Lockett SJ.

Cytometry A. 2015 Feb;87(2):99-100. doi: 10.1002/cyto.a.22617. Epub 2014 Dec 16. No abstract available.

9.

Nucleocytoplasmic shuttling of valosin-containing protein (VCP/p97) regulated by its N domain and C-terminal region.

Song C, Wang Q, Song C, Lockett SJ, Colburn NH, Li CC, Wang JM, Rogers TJ.

Biochim Biophys Acta. 2015 Jan;1853(1):222-32. doi: 10.1016/j.bbamcr.2014.10.019. Epub 2014 Oct 30.

10.

TCR Microclusters pre-exist and contain molecules necessary for TCR signal transduction.

Crites TJ, Padhan K, Muller J, Krogsgaard M, Gudla PR, Lockett SJ, Varma R.

J Immunol. 2014 Jul 1;193(1):56-67. doi: 10.4049/jimmunol.1400315. Epub 2014 May 23.

11.

Segmentation and quantitative analysis of individual cells in developmental tissues.

Nandy K, Kim J, McCullough DP, McAuliffe M, Meaburn KJ, Yamaguchi TP, Gudla PR, Lockett SJ.

Methods Mol Biol. 2014;1092:235-53. doi: 10.1007/978-1-60327-292-6_16.

PMID:
24318825
12.

Microscopy of molecular interactions.

Vereb G, Lockett SJ.

Cytometry A. 2013 Sep;83(9):763-4. doi: 10.1002/cyto.a.22339. No abstract available.

13.

Activation of different split functionalities on re-association of RNA-DNA hybrids.

Afonin KA, Viard M, Martins AN, Lockett SJ, Maciag AE, Freed EO, Heldman E, Jaeger L, Blumenthal R, Shapiro BA.

Nat Nanotechnol. 2013 Apr;8(4):296-304. doi: 10.1038/nnano.2013.44. Epub 2013 Mar 31.

14.

IL-27 inhibits HIV-1 infection in human macrophages by down-regulating host factor SPTBN1 during monocyte to macrophage differentiation.

Dai L, Lidie KB, Chen Q, Adelsberger JW, Zheng X, Huang D, Yang J, Lempicki RA, Rehman T, Dewar RL, Wang Y, Hornung RL, Canizales KA, Lockett SJ, Lane HC, Imamichi T.

J Exp Med. 2013 Mar 11;210(3):517-34. doi: 10.1084/jem.20120572. Epub 2013 Mar 4.

15.

Ty1 gag enhances the stability and nuclear export of Ty1 mRNA.

Checkley MA, Mitchell JA, Eizenstat LD, Lockett SJ, Garfinkel DJ.

Traffic. 2013 Jan;14(1):57-69. doi: 10.1111/tra.12013. Epub 2012 Oct 17.

16.

Ranked retrieval of segmented nuclei for objective assessment of cancer gene repositioning.

Cukierski WJ, Nandy K, Gudla P, Meaburn KJ, Misteli T, Foran DJ, Lockett SJ.

BMC Bioinformatics. 2012 Sep 12;13:232. doi: 10.1186/1471-2105-13-232.

17.

Automatic segmentation and supervised learning-based selection of nuclei in cancer tissue images.

Nandy K, Gudla PR, Amundsen R, Meaburn KJ, Misteli T, Lockett SJ.

Cytometry A. 2012 Sep;81(9):743-54. doi: 10.1002/cyto.a.22097. Epub 2012 Jul 31.

18.

Supervised learning framework for screening nuclei in tissue sections.

Nandy K, Gudla PR, Amundsen R, Meaburn KJ, Misteli T, Lockett SJ.

Conf Proc IEEE Eng Med Biol Soc. 2011;2011:5989-92. doi: 10.1109/IEMBS.2011.6091480.

19.

Schweinfurthin A selectively inhibits proliferation and Rho signaling in glioma and neurofibromatosis type 1 tumor cells in a NF1-GRD-dependent manner.

Turbyville TJ, Gürsel DB, Tuskan RG, Walrath JC, Lipschultz CA, Lockett SJ, Wiemer DF, Beutler JA, Reilly KM.

Mol Cancer Ther. 2010 May;9(5):1234-43. doi: 10.1158/1535-7163.MCT-09-0834. Epub 2010 May 4.

20.

Disease-specific gene repositioning in breast cancer.

Meaburn KJ, Gudla PR, Khan S, Lockett SJ, Misteli T.

J Cell Biol. 2009 Dec 14;187(6):801-12. doi: 10.1083/jcb.200909127.

21.

Automatic nuclei segmentation and spatial FISH analysis for cancer detection.

Nandy K, Gudla PR, Meaburn KJ, Misteli T, Lockett SJ.

Conf Proc IEEE Eng Med Biol Soc. 2009;2009:6718-21. doi: 10.1109/IEMBS.2009.5332922.

22.

P-body components are required for Ty1 retrotransposition during assembly of retrotransposition-competent virus-like particles.

Checkley MA, Nagashima K, Lockett SJ, Nyswaner KM, Garfinkel DJ.

Mol Cell Biol. 2010 Jan;30(2):382-98. doi: 10.1128/MCB.00251-09. Epub 2009 Nov 9.

23.

Loss of SUMO1 in mice affects RanGAP1 localization and formation of PML nuclear bodies, but is not lethal as it can be compensated by SUMO2 or SUMO3.

Evdokimov E, Sharma P, Lockett SJ, Lualdi M, Kuehn MR.

J Cell Sci. 2008 Dec 15;121(Pt 24):4106-13. doi: 10.1242/jcs.038570. Epub 2008 Nov 25.

24.

Three-dimensional image visualization and analysis.

Lockett SJ.

Curr Protoc Cytom. 2001 May;Chapter 10:Unit 10.10. doi: 10.1002/0471142956.cy1010s10.

PMID:
18770674
25.

Segmentation of whole cells and cell nuclei from 3-D optical microscope images using dynamic programming.

McCullough DP, Gudla PR, Harris BS, Collins JA, Meaburn KJ, Nakaya MA, Yamaguchi TP, Misteli T, Lockett SJ.

IEEE Trans Med Imaging. 2008 May;27(5):723-34. doi: 10.1109/TMI.2007.913135.

26.

A high-throughput system for segmenting nuclei using multiscale techniques.

Gudla PR, Nandy K, Collins J, Meaburn KJ, Misteli T, Lockett SJ.

Cytometry A. 2008 May;73(5):451-66. doi: 10.1002/cyto.a.20550.

27.

The heavy metal cadmium induces valosin-containing protein (VCP)-mediated aggresome formation.

Song C, Xiao Z, Nagashima K, Li CC, Lockett SJ, Dai RM, Cho EH, Conrads TP, Veenstra TD, Colburn NH, Wang Q, Wang JM.

Toxicol Appl Pharmacol. 2008 May 1;228(3):351-63. doi: 10.1016/j.taap.2007.12.026. Epub 2008 Jan 8.

28.

Rationally designed inhibitors identify STAT3 N-domain as a promising anticancer drug target.

Timofeeva OA, Gaponenko V, Lockett SJ, Tarasov SG, Jiang S, Michejda CJ, Perantoni AO, Tarasova NI.

ACS Chem Biol. 2007 Dec 21;2(12):799-809.

PMID:
18154267
29.

Restricted lateral mobility of plasma membrane CD4 impairs HIV-1 envelope glycoprotein mediated fusion.

Rawat SS, Zimmerman C, Johnson BT, Cho E, Lockett SJ, Blumenthal R, Puri A.

Mol Membr Biol. 2008 Jan;25(1):83-94.

30.
31.

Coherent anti-stokes Raman scattering microscopy: a biological review.

Rodriguez LG, Lockett SJ, Holtom GR.

Cytometry A. 2006 Aug 1;69(8):779-91. Review.

32.

Novel lymphotoxin alpha (LTalpha) knockout mice with unperturbed tumor necrosis factor expression: reassessing LTalpha biological functions.

Liepinsh DJ, Grivennikov SI, Klarmann KD, Lagarkova MA, Drutskaya MS, Lockett SJ, Tessarollo L, McAuliffe M, Keller JR, Kuprash DV, Nedospasov SA.

Mol Cell Biol. 2006 Jun;26(11):4214-25.

33.

Phosphatidylinositol (4,5) bisphosphate regulates HIV-1 Gag targeting to the plasma membrane.

Ono A, Ablan SD, Lockett SJ, Nagashima K, Freed EO.

Proc Natl Acad Sci U S A. 2004 Oct 12;101(41):14889-94. Epub 2004 Oct 1.

34.

Identification of probabilistic transcriptional switches in the Ly49 gene cluster: a eukaryotic mechanism for selective gene activation.

Saleh A, Davies GE, Pascal V, Wright PW, Hodge DL, Cho EH, Lockett SJ, Abshari M, Anderson SK.

Immunity. 2004 Jul;21(1):55-66.

35.

In situ analyses of genome instability in breast cancer.

Chin K, de Solorzano CO, Knowles D, Jones A, Chou W, Rodriguez EG, Kuo WL, Ljung BM, Chew K, Myambo K, Miranda M, Krig S, Garbe J, Stampfer M, Yaswen P, Gray JW, Lockett SJ.

Nat Genet. 2004 Sep;36(9):984-8. Epub 2004 Aug 8.

PMID:
15300252
36.

Human CD8+ T cells store RANTES in a unique secretory compartment and release it rapidly after TcR stimulation.

Catalfamo M, Karpova T, McNally J, Costes SV, Lockett SJ, Bos E, Peters PJ, Henkart PA.

Immunity. 2004 Feb;20(2):219-30.

37.

The transformation suppressor Pdcd4 is a novel eukaryotic translation initiation factor 4A binding protein that inhibits translation.

Yang HS, Jansen AP, Komar AA, Zheng X, Merrick WC, Costes S, Lockett SJ, Sonenberg N, Colburn NH.

Mol Cell Biol. 2003 Jan;23(1):26-37.

38.

System for combined three-dimensional morphological and molecular analysis of thick tissue specimens.

Fernandez-Gonzalez R, Jones A, Garcia-Rodriguez E, Chen PY, Idica A, Lockett SJ, Barcellos-Hoff MH, Ortiz-De-Solorzano C.

Microsc Res Tech. 2002 Dec 15;59(6):522-30. Review.

39.

Lipid rafts and the local density of ErbB proteins influence the biological role of homo- and heteroassociations of ErbB2.

Nagy P, Vereb G, Sebestyén Z, Horváth G, Lockett SJ, Damjanovich S, Park JW, Jovin TM, Szöllosi J.

J Cell Sci. 2002 Nov 15;115(Pt 22):4251-62.

40.

Modulation of lens cell adhesion molecules by particle beams.

McNamara MP, Bjornstad KA, Chang PY, Chou W, Lockett SJ, Blakely EA.

Phys Med. 2001;17 Suppl 1:247-8.

PMID:
11776988
41.

Segmentation of nuclei and cells using membrane related protein markers.

De Solorzano CO, Malladi R, Lelièvre SA, Lockett SJ.

J Microsc. 2001 Mar;201(Pt 3):404-15. Erratum in: J Microsc. 2006 Apr;222(Pt 1):67.

42.

Segmentation of confocal microscope images of cell nuclei in thick tissue sections.

Ortiz de Solórzano C, García Rodriguez E, Jones A, Pinkel D, Gray JW, Sudar D, Lockett SJ.

J Microsc. 1999 Mar;193(Pt 3):212-26.

43.

Intensity-based energy transfer measurements in digital imaging microscopy.

Nagy P, Vámosi G, Bodnár A, Lockett SJ, Szöllösi J.

Eur Biophys J. 1998;27(4):377-89.

PMID:
9691467
44.

EGF-induced redistribution of erbB2 on breast tumor cells: flow and image cytometric energy transfer measurements.

Nagy P, Bene L, Balázs M, Hyun WC, Lockett SJ, Chiang NY, Waldman F, Feuerstein BG, Damjanovich S, Szöllosi J.

Cytometry. 1998 Jun 1;32(2):120-31.

45.

Efficient, interactive, and three-dimensional segmentation of cell nuclei in thick tissue sections.

Lockett SJ, Sudar D, Thompson CT, Pinkel D, Gray JW.

Cytometry. 1998 Apr 1;31(4):275-86.

46.

Genotype/phenotype analyses of low frequency tumor cells using computerize image microscopy.

Litle VR, Lockett SJ, Pallavicini MG.

Cytometry. 1996 Apr 1;23(4):344-9.

47.

Autofluorescence correction for fluorescence in situ hybridization.

Szöllösi J, Lockett SJ, Balázs M, Waldman FM.

Cytometry. 1995 Aug 1;20(4):356-61.

48.
49.

Detection of human papillomavirus type 16/18 DNA in cervicovaginal cells by fluorescence based in situ hybridization and automated image cytometry.

Siadat-Pajouh M, Periasamy A, Ayscue AH, Moscicki AB, Palefsky JM, Walton L, DeMars LR, Power JD, Herman B, Lockett SJ.

Cytometry. 1994 Mar 1;15(3):245-57.

50.

Co-localization of the tumor-suppressor protein p53 and human papillomavirus E6 protein in human cervical carcinoma cell lines.

Liang XH, Volkmann M, Klein R, Herman B, Lockett SJ.

Oncogene. 1993 Oct;8(10):2645-52.

PMID:
8397367

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