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Items: 1 to 50 of 104

1.

The Natural Product Butylcycloheptyl Prodiginine Binds Pre-miR-21, Inhibits Dicer-Mediated Processing of Pre-miR-21, and Blocks Cellular Proliferation.

Matarlo JS, Krumpe LRH, Heinz WF, Oh D, Shenoy SR, Thomas CL, Goncharova EI, Lockett SJ, O'Keefe BR.

Cell Chem Biol. 2019 Aug 15;26(8):1133-1142.e4. doi: 10.1016/j.chembiol.2019.04.011. Epub 2019 May 30.

PMID:
31155509
2.

Photoinducible Oncometabolite Detection.

Kulkarni RA, Briney CA, Crooks DR, Bergholtz SE, Mushti C, Lockett SJ, Lane AN, Fan TW, Swenson RE, Marston Linehan W, Meier JL.

Chembiochem. 2019 Feb 1;20(3):360-365. doi: 10.1002/cbic.201800651. Epub 2018 Dec 13.

PMID:
30358041
3.

Defective cortex glia plasma membrane structure underlies light-induced epilepsy in cpes mutants.

Kunduri G, Turner-Evans D, Konya Y, Izumi Y, Nagashima K, Lockett S, Holthuis J, Bamba T, Acharya U, Acharya JK.

Proc Natl Acad Sci U S A. 2018 Sep 18;115(38):E8919-E8928. doi: 10.1073/pnas.1808463115. Epub 2018 Sep 5.

4.

Understanding the tumour micro-environment communication network from an NOS2/COX2 perspective.

Basudhar D, Bharadwaj G, Somasundaram V, Cheng RYS, Ridnour LA, Fujita M, Lockett SJ, Anderson SK, McVicar DW, Wink DA.

Br J Pharmacol. 2019 Jan;176(2):155-176. doi: 10.1111/bph.14488. Epub 2018 Nov 6. Review.

PMID:
30152521
5.

A novel sheet-like virus particle array is a hallmark of Zika virus infection.

Liu J, Kline BA, Kenny TA, Smith DR, Soloveva V, Beitzel B, Pang S, Lockett S, Hess HF, Palacios G, Kuhn JH, Sun MG, Zeng X.

Emerg Microbes Infect. 2018 Apr 25;7(1):69. doi: 10.1038/s41426-018-0071-8.

6.

Virtual peer-delivered memory intervention: a single-case experimental design in an adolescent with chronic memory impairment.

Cooper JM, Lockett S, McIlroy A, Gonzalez L.

Brain Inj. 2018;32(3):350-362. doi: 10.1080/02699052.2017.1419282. Epub 2017 Dec 28.

PMID:
29283279
7.

Coexpression of NOS2 and COX2 accelerates tumor growth and reduces survival in estrogen receptor-negative breast cancer.

Basudhar D, Glynn SA, Greer M, Somasundaram V, No JH, Scheiblin DA, Garrido P, Heinz WF, Ryan AE, Weiss JM, Cheng RYS, Ridnour LA, Lockett SJ, McVicar DW, Ambs S, Wink DA.

Proc Natl Acad Sci U S A. 2017 Dec 5;114(49):13030-13035. doi: 10.1073/pnas.1709119114. Epub 2017 Oct 27.

8.

Reducing the efficiency-stability-cost gap of organic photovoltaics with highly efficient and stable small molecule acceptor ternary solar cells.

Baran D, Ashraf RS, Hanifi DA, Abdelsamie M, Gasparini N, Röhr JA, Holliday S, Wadsworth A, Lockett S, Neophytou M, Emmott CJ, Nelson J, Brabec CJ, Amassian A, Salleo A, Kirchartz T, Durrant JR, McCulloch I.

Nat Mater. 2017 Mar;16(3):363-369. doi: 10.1038/nmat4797. Epub 2016 Nov 21.

9.

pH Alkalinization by Chloroquine Suppresses Pathogenic Burkholderia Type 6 Secretion System 1 and Multinucleated Giant Cells.

Chua J, Senft JL, Lockett SJ, Brett PJ, Burtnick MN, DeShazer D, Friedlander AM.

Infect Immun. 2016 Dec 29;85(1). pii: e00586-16. doi: 10.1128/IAI.00586-16. Print 2017 Jan.

10.

Cytoskeletal abnormalities and neutrophil dysfunction in WDR1 deficiency.

Kuhns DB, Fink DL, Choi U, Sweeney C, Lau K, Priel DL, Riva D, Mendez L, Uzel G, Freeman AF, Olivier KN, Anderson VL, Currens R, Mackley V, Kang A, Al-Adeli M, Mace E, Orange JS, Kang E, Lockett SJ, Chen, Steinbach PJ, Hsu AP, Zarember KA, Malech HL, Gallin JI, Holland SM.

Blood. 2016 Oct 27;128(17):2135-2143. Epub 2016 Aug 24.

11.

LZTFL1 Upregulated by All-Trans Retinoic Acid during CD4+ T Cell Activation Enhances IL-5 Production.

Jiang H, Promchan K, Lin BR, Lockett S, Chen D, Marshall H, Badralmaa Y, Natarajan V.

J Immunol. 2016 Feb 1;196(3):1081-90. doi: 10.4049/jimmunol.1500719. Epub 2015 Dec 23.

12.

Dynamics of HIV-1 RNA Near the Plasma Membrane during Virus Assembly.

Sardo L, Hatch SC, Chen J, Nikolaitchik O, Burdick RC, Chen D, Westlake CJ, Lockett S, Pathak VK, Hu WS.

J Virol. 2015 Nov;89(21):10832-40. doi: 10.1128/JVI.01146-15. Epub 2015 Aug 19.

13.

Synthesis and applications of RNAs with position-selective labelling and mosaic composition.

Liu Y, Holmstrom E, Zhang J, Yu P, Wang J, Dyba MA, Chen D, Ying J, Lockett S, Nesbitt DJ, Ferré-D'Amaré AR, Sousa R, Stagno JR, Wang YX.

Nature. 2015 Jun 18;522(7556):368-72. doi: 10.1038/nature14352. Epub 2015 May 4.

14.

Speeding up image cytometry.

Lockett SJ.

Cytometry A. 2015 Feb;87(2):99-100. doi: 10.1002/cyto.a.22617. Epub 2014 Dec 16. No abstract available.

15.

Nucleocytoplasmic shuttling of valosin-containing protein (VCP/p97) regulated by its N domain and C-terminal region.

Song C, Wang Q, Song C, Lockett SJ, Colburn NH, Li CC, Wang JM, Rogers TJ.

Biochim Biophys Acta. 2015 Jan;1853(1):222-32. doi: 10.1016/j.bbamcr.2014.10.019. Epub 2014 Oct 30.

16.

Cytoplasmic HIV-1 RNA is mainly transported by diffusion in the presence or absence of Gag protein.

Chen J, Grunwald D, Sardo L, Galli A, Plisov S, Nikolaitchik OA, Chen D, Lockett S, Larson DR, Pathak VK, Hu WS.

Proc Natl Acad Sci U S A. 2014 Dec 2;111(48):E5205-13. doi: 10.1073/pnas.1413169111. Epub 2014 Nov 17.

17.

TCR Microclusters pre-exist and contain molecules necessary for TCR signal transduction.

Crites TJ, Padhan K, Muller J, Krogsgaard M, Gudla PR, Lockett SJ, Varma R.

J Immunol. 2014 Jul 1;193(1):56-67. doi: 10.4049/jimmunol.1400315. Epub 2014 May 23.

18.

Ceramide transfer protein deficiency compromises organelle function and leads to senescence in primary cells.

Rao RP, Scheffer L, Srideshikan SM, Parthibane V, Kosakowska-Cholody T, Masood MA, Nagashima K, Gudla P, Lockett S, Acharya U, Acharya JK.

PLoS One. 2014 Mar 18;9(3):e92142. doi: 10.1371/journal.pone.0092142. eCollection 2014.

19.

Quantitative analysis of F-actin redistribution in astrocytoma cells treated with candidate pharmaceuticals.

Lockett S, Verma C, Brafman A, Gudla P, Nandy K, Mimaki Y, Fuchs PL, Jaja J, Reilly KM, Beutler J, Turbyville TJ.

Cytometry A. 2014 Jun;85(6):512-21. doi: 10.1002/cyto.a.22442. Epub 2014 Feb 11.

20.

Segmentation and quantitative analysis of individual cells in developmental tissues.

Nandy K, Kim J, McCullough DP, McAuliffe M, Meaburn KJ, Yamaguchi TP, Gudla PR, Lockett SJ.

Methods Mol Biol. 2014;1092:235-53. doi: 10.1007/978-1-60327-292-6_16.

PMID:
24318825
21.

Microscopy of molecular interactions.

Vereb G, Lockett SJ.

Cytometry A. 2013 Sep;83(9):763-4. doi: 10.1002/cyto.a.22339. No abstract available.

22.

Activation of different split functionalities on re-association of RNA-DNA hybrids.

Afonin KA, Viard M, Martins AN, Lockett SJ, Maciag AE, Freed EO, Heldman E, Jaeger L, Blumenthal R, Shapiro BA.

Nat Nanotechnol. 2013 Apr;8(4):296-304. doi: 10.1038/nnano.2013.44. Epub 2013 Mar 31.

23.

IL-27 inhibits HIV-1 infection in human macrophages by down-regulating host factor SPTBN1 during monocyte to macrophage differentiation.

Dai L, Lidie KB, Chen Q, Adelsberger JW, Zheng X, Huang D, Yang J, Lempicki RA, Rehman T, Dewar RL, Wang Y, Hornung RL, Canizales KA, Lockett SJ, Lane HC, Imamichi T.

J Exp Med. 2013 Mar 11;210(3):517-34. doi: 10.1084/jem.20120572. Epub 2013 Mar 4.

24.

Cripto-1 enhances the canonical Wnt/β-catenin signaling pathway by binding to LRP5 and LRP6 co-receptors.

Nagaoka T, Karasawa H, Turbyville T, Rangel MC, Castro NP, Gonzales M, Baker A, Seno M, Lockett S, Greer YE, Rubin JS, Salomon DS, Bianco C.

Cell Signal. 2013 Jan;25(1):178-89. doi: 10.1016/j.cellsig.2012.09.024. Epub 2012 Sep 27.

25.

Ty1 gag enhances the stability and nuclear export of Ty1 mRNA.

Checkley MA, Mitchell JA, Eizenstat LD, Lockett SJ, Garfinkel DJ.

Traffic. 2013 Jan;14(1):57-69. doi: 10.1111/tra.12013. Epub 2012 Oct 17.

26.

Ranked retrieval of segmented nuclei for objective assessment of cancer gene repositioning.

Cukierski WJ, Nandy K, Gudla P, Meaburn KJ, Misteli T, Foran DJ, Lockett SJ.

BMC Bioinformatics. 2012 Sep 12;13:232. doi: 10.1186/1471-2105-13-232.

27.

Automatic segmentation and supervised learning-based selection of nuclei in cancer tissue images.

Nandy K, Gudla PR, Amundsen R, Meaburn KJ, Misteli T, Lockett SJ.

Cytometry A. 2012 Sep;81(9):743-54. doi: 10.1002/cyto.a.22097. Epub 2012 Jul 31.

28.

Supervised learning framework for screening nuclei in tissue sections.

Nandy K, Gudla PR, Amundsen R, Meaburn KJ, Misteli T, Lockett SJ.

Conf Proc IEEE Eng Med Biol Soc. 2011;2011:5989-92. doi: 10.1109/IEMBS.2011.6091480.

29.

Using a semi-structured interview to explore imagery experienced during social anxiety for clients with a diagnosis of psychosis: an exploratory study conducted within an early intervention for psychosis service.

Lockett SH, Hatton J, Turner R, Stubbins C, Hodgekins J, Fowler D.

Behav Cogn Psychother. 2012 Jan;40(1):55-68. doi: 10.1017/S1352465811000439. Epub 2011 Jul 5.

PMID:
21729340
30.

Human T-cell leukemia virus type 1 p8 protein increases cellular conduits and virus transmission.

Van Prooyen N, Gold H, Andresen V, Schwartz O, Jones K, Ruscetti F, Lockett S, Gudla P, Venzon D, Franchini G.

Proc Natl Acad Sci U S A. 2010 Nov 30;107(48):20738-43. doi: 10.1073/pnas.1009635107. Epub 2010 Nov 12.

31.

Fullerenol cytotoxicity in kidney cells is associated with cytoskeleton disruption, autophagic vacuole accumulation, and mitochondrial dysfunction.

Johnson-Lyles DN, Peifley K, Lockett S, Neun BW, Hansen M, Clogston J, Stern ST, McNeil SE.

Toxicol Appl Pharmacol. 2010 Nov 1;248(3):249-58. doi: 10.1016/j.taap.2010.08.008. Epub 2010 Aug 14.

32.

Schweinfurthin A selectively inhibits proliferation and Rho signaling in glioma and neurofibromatosis type 1 tumor cells in a NF1-GRD-dependent manner.

Turbyville TJ, Gürsel DB, Tuskan RG, Walrath JC, Lipschultz CA, Lockett SJ, Wiemer DF, Beutler JA, Reilly KM.

Mol Cancer Ther. 2010 May;9(5):1234-43. doi: 10.1158/1535-7163.MCT-09-0834. Epub 2010 May 4.

33.

Disease-specific gene repositioning in breast cancer.

Meaburn KJ, Gudla PR, Khan S, Lockett SJ, Misteli T.

J Cell Biol. 2009 Dec 14;187(6):801-12. doi: 10.1083/jcb.200909127.

34.

Automatic nuclei segmentation and spatial FISH analysis for cancer detection.

Nandy K, Gudla PR, Meaburn KJ, Misteli T, Lockett SJ.

Conf Proc IEEE Eng Med Biol Soc. 2009;2009:6718-21. doi: 10.1109/IEMBS.2009.5332922.

35.

Quantifying the astrocytoma cell response to candidate pharmaceutical from F-ACTIN image analysis.

Cui C, JaJa J, Turbyville T, Beutler J, Gudla P, Nandy K, Lockett S.

Conf Proc IEEE Eng Med Biol Soc. 2009;2009:5768-71. doi: 10.1109/IEMBS.2009.5332528.

PMID:
19963655
36.

P-body components are required for Ty1 retrotransposition during assembly of retrotransposition-competent virus-like particles.

Checkley MA, Nagashima K, Lockett SJ, Nyswaner KM, Garfinkel DJ.

Mol Cell Biol. 2010 Jan;30(2):382-98. doi: 10.1128/MCB.00251-09. Epub 2009 Nov 9.

37.

High efficiency of HIV-1 genomic RNA packaging and heterozygote formation revealed by single virion analysis.

Chen J, Nikolaitchik O, Singh J, Wright A, Bencsics CE, Coffin JM, Ni N, Lockett S, Pathak VK, Hu WS.

Proc Natl Acad Sci U S A. 2009 Aug 11;106(32):13535-40. doi: 10.1073/pnas.0906822106. Epub 2009 Jul 23.

38.

Loss of SUMO1 in mice affects RanGAP1 localization and formation of PML nuclear bodies, but is not lethal as it can be compensated by SUMO2 or SUMO3.

Evdokimov E, Sharma P, Lockett SJ, Lualdi M, Kuehn MR.

J Cell Sci. 2008 Dec 15;121(Pt 24):4106-13. doi: 10.1242/jcs.038570. Epub 2008 Nov 25.

39.

Three-dimensional image visualization and analysis.

Lockett SJ.

Curr Protoc Cytom. 2001 May;Chapter 10:Unit 10.10. doi: 10.1002/0471142956.cy1010s10.

PMID:
18770674
40.

Inhibition of metastatic outgrowth from single dormant tumor cells by targeting the cytoskeleton.

Barkan D, Kleinman H, Simmons JL, Asmussen H, Kamaraju AK, Hoenorhoff MJ, Liu ZY, Costes SV, Cho EH, Lockett S, Khanna C, Chambers AF, Green JE.

Cancer Res. 2008 Aug 1;68(15):6241-50. doi: 10.1158/0008-5472.CAN-07-6849.

41.

Surviving blood loss using hydrogen sulfide.

Morrison ML, Blackwood JE, Lockett SL, Iwata A, Winn RK, Roth MB.

J Trauma. 2008 Jul;65(1):183-8. doi: 10.1097/TA.0b013e3181507579.

PMID:
18580516
42.

Segmentation of whole cells and cell nuclei from 3-D optical microscope images using dynamic programming.

McCullough DP, Gudla PR, Harris BS, Collins JA, Meaburn KJ, Nakaya MA, Yamaguchi TP, Misteli T, Lockett SJ.

IEEE Trans Med Imaging. 2008 May;27(5):723-34. doi: 10.1109/TMI.2007.913135.

43.

A high-throughput system for segmenting nuclei using multiscale techniques.

Gudla PR, Nandy K, Collins J, Meaburn KJ, Misteli T, Lockett SJ.

Cytometry A. 2008 May;73(5):451-66. doi: 10.1002/cyto.a.20550.

44.

Allele-specific nuclear positioning of the monoallelically expressed astrocyte marker GFAP.

Takizawa T, Gudla PR, Guo L, Lockett S, Misteli T.

Genes Dev. 2008 Feb 15;22(4):489-98. doi: 10.1101/gad.1634608.

45.

The heavy metal cadmium induces valosin-containing protein (VCP)-mediated aggresome formation.

Song C, Xiao Z, Nagashima K, Li CC, Lockett SJ, Dai RM, Cho EH, Conrads TP, Veenstra TD, Colburn NH, Wang Q, Wang JM.

Toxicol Appl Pharmacol. 2008 May 1;228(3):351-63. doi: 10.1016/j.taap.2007.12.026. Epub 2008 Jan 8.

46.

Rationally designed inhibitors identify STAT3 N-domain as a promising anticancer drug target.

Timofeeva OA, Gaponenko V, Lockett SJ, Tarasov SG, Jiang S, Michejda CJ, Perantoni AO, Tarasova NI.

ACS Chem Biol. 2007 Dec 21;2(12):799-809.

PMID:
18154267
47.

Restricted lateral mobility of plasma membrane CD4 impairs HIV-1 envelope glycoprotein mediated fusion.

Rawat SS, Zimmerman C, Johnson BT, Cho E, Lockett SJ, Blumenthal R, Puri A.

Mol Membr Biol. 2008 Jan;25(1):83-94.

48.

Interleukin 10 and TNFalpha synergistically enhance the expression of the G protein-coupled formylpeptide receptor 2 in microglia.

Iribarren P, Chen K, Gong W, Cho EH, Lockett S, Uranchimeg B, Wang JM.

Neurobiol Dis. 2007 Jul;27(1):90-8. Epub 2007 May 5.

49.

Sphingomyelinase restricts the lateral diffusion of CD4 and inhibits human immunodeficiency virus fusion.

Finnegan CM, Rawat SS, Cho EH, Guiffre DL, Lockett S, Merrill AH Jr, Blumenthal R.

J Virol. 2007 May;81(10):5294-304. Epub 2007 Mar 7.

50.

Induction of the formyl peptide receptor 2 in microglia by IFN-gamma and synergy with CD40 ligand.

Chen K, Iribarren P, Huang J, Zhang L, Gong W, Cho EH, Lockett S, Dunlop NM, Wang JM.

J Immunol. 2007 Feb 1;178(3):1759-66.

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