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Items: 1 to 50 of 205

1.

Biliary Obstruction Promotes Multilineage Differentiation of Hepatic Stem Cells.

Yovchev MI, Lee EJ, Rodriguez-Silva W, Locker J, Oertel M.

Hepatol Commun. 2019 May 23;3(8):1137-1150. doi: 10.1002/hep4.1367. eCollection 2019 Aug.

2.

The genetic basis of 3-hydroxypropanoate metabolism in Cupriavidus necator H16.

Arenas-López C, Locker J, Orol D, Walter F, Busche T, Kalinowski J, Minton NP, Kovács K, Winzer K.

Biotechnol Biofuels. 2019 Jun 17;12:150. doi: 10.1186/s13068-019-1489-5. eCollection 2019.

3.

Pharmacologic Inhibition of Epidermal Growth Factor Receptor Suppresses Nonalcoholic Fatty Liver Disease in a Murine Fast-Food Diet Model.

Bhushan B, Banerjee S, Paranjpe S, Koral K, Mars WM, Stoops JW, Orr A, Bowen WC, Locker J, Michalopoulos GK.

Hepatology. 2019 Nov;70(5):1546-1563. doi: 10.1002/hep.30696. Epub 2019 Jun 19.

PMID:
31063640
4.

Shear stress and oxygen availability drive differential changes in opossum kidney proximal tubule cell metabolism and endocytosis.

Ren Q, Gliozzi ML, Rittenhouse NL, Edmunds LR, Rbaibi Y, Locker JD, Poholek AC, Jurczak MJ, Baty CJ, Weisz OA.

Traffic. 2019 Jun;20(6):448-459. doi: 10.1111/tra.12648. Epub 2019 May 9.

5.

Binding of Drug-Activated CAR/Nr1i3 Alters Metabolic Regulation in the Liver.

Tian J, Marino R, Johnson C, Locker J.

iScience. 2018 Nov 30;9:209-228. doi: 10.1016/j.isci.2018.10.018. Epub 2018 Oct 22.

6.

Constitutive Activation of the Human Aryl Hydrocarbon Receptor in Mice Promotes Hepatocarcinogenesis Independent of Its Coactivator Gadd45b.

Lu P, Cai X, Guo Y, Xu M, Tian J, Locker J, Xie W.

Toxicol Sci. 2019 Feb 1;167(2):581-592. doi: 10.1093/toxsci/kfy263.

PMID:
30346592
7.

Loss of hepatocyte β-catenin protects mice from experimental porphyria-associated liver injury.

Saggi H, Maitra D, Jiang A, Zhang R, Wang P, Cornuet P, Singh S, Locker J, Ma X, Dailey H, Abrams M, Omary MB, Monga SP, Nejak-Bowen K.

J Hepatol. 2019 Jan;70(1):108-117. doi: 10.1016/j.jhep.2018.09.023. Epub 2018 Oct 1.

8.

Hdac1 Regulates Differentiation of Bipotent Liver Progenitor Cells During Regeneration via Sox9b and Cdk8.

Ko S, Russell JO, Tian J, Gao C, Kobayashi M, Feng R, Yuan X, Shao C, Ding H, Poddar M, Singh S, Locker J, Weng HL, Monga SP, Shin D.

Gastroenterology. 2019 Jan;156(1):187-202.e14. doi: 10.1053/j.gastro.2018.09.039. Epub 2018 Sep 26.

9.

Activin A is a prominent autocrine regulator of hepatocyte growth arrest.

Haridoss S, Yovchev MI, Schweizer H, Megherhi S, Beecher M, Locker J, Oertel M.

Hepatol Commun. 2017 Nov 3;1(9):852-870. doi: 10.1002/hep4.1106. eCollection 2017 Nov.

10.

β-Catenin regulation of farnesoid X receptor signaling and bile acid metabolism during murine cholestasis.

Thompson MD, Moghe A, Cornuet P, Marino R, Tian J, Wang P, Ma X, Abrams M, Locker J, Monga SP, Nejak-Bowen K.

Hepatology. 2018 Mar;67(3):955-971. doi: 10.1002/hep.29371. Epub 2018 Jan 26.

11.

The transcriptome of the Didelphis virginiana opossum kidney OK proximal tubule cell line.

Eshbach ML, Sethi R, Avula R, Lamb J, Hollingshead DJ, Finegold DN, Locker JD, Chandran UR, Weisz OA.

Am J Physiol Renal Physiol. 2017 Sep 1;313(3):F585-F595. doi: 10.1152/ajprenal.00228.2017. Epub 2017 Jun 14.

12.

Triple Staining Including FOXA2 Identifies Stem Cell Lineages Undergoing Hepatic and Biliary Differentiation in Cirrhotic Human Liver.

Rogler CE, Bebawee R, Matarlo J, Locker J, Pattamanuch N, Gupta S, Rogler LE.

J Histochem Cytochem. 2017 Jan;65(1):33-46. doi: 10.1369/0022155416675153. Epub 2016 Nov 24.

13.

p27T187A knockin identifies Skp2/Cks1 pocket inhibitors for advanced prostate cancer.

Zhao H, Lu Z, Bauzon F, Fu H, Cui J, Locker J, Zhu L.

Oncogene. 2017 Jan 5;36(1):60-70. doi: 10.1038/onc.2016.175. Epub 2016 May 16.

14.

Biliary fibrosis drives liver repopulation and phenotype transition of transplanted hepatocytes.

Yovchev MI, Locker J, Oertel M.

J Hepatol. 2016 Jun;64(6):1348-57. doi: 10.1016/j.jhep.2016.01.036. Epub 2016 Feb 5.

15.

Experimental Model for Successful Liver Cell Therapy by Lenti TTR-YapERT2 Transduced Hepatocytes with Tamoxifen Control of Yap Subcellular Location.

Yovchev M, Jaber FL, Lu Z, Patel S, Locker J, Rogler LE, Murray JW, Sudol M, Dabeva MD, Zhu L, Shafritz DA.

Sci Rep. 2016 Jan 14;6:19275. doi: 10.1038/srep19275.

16.

Genome Wide Methylome Alterations in Lung Cancer.

Mullapudi N, Ye B, Suzuki M, Fazzari M, Han W, Shi MK, Marquardt G, Lin J, Wang T, Keller S, Zhu C, Locker JD, Spivack SD.

PLoS One. 2015 Dec 18;10(12):e0143826. doi: 10.1371/journal.pone.0143826. eCollection 2015.

17.

Precise let-7 expression levels balance organ regeneration against tumor suppression.

Wu L, Nguyen LH, Zhou K, de Soysa TY, Li L, Miller JB, Tian J, Locker J, Zhang S, Shinoda G, Seligson MT, Zeitels LR, Acharya A, Wang SC, Mendell JT, He X, Nishino J, Morrison SJ, Siegwart DJ, Daley GQ, Shyh-Chang N, Zhu H.

Elife. 2015 Oct 7;4:e09431. doi: 10.7554/eLife.09431.

18.

Resetting the transcription factor network reverses terminal chronic hepatic failure.

Nishikawa T, Bell A, Brooks JM, Setoyama K, Melis M, Han B, Fukumitsu K, Handa K, Tian J, Kaestner KH, Vodovotz Y, Locker J, Soto-Gutierrez A, Fox IJ.

J Clin Invest. 2015 Apr;125(4):1533-44. doi: 10.1172/JCI73137. Epub 2015 Mar 16.

19.

Femoral nerve infusion after primary total knee arthroplasty: a prospective, double-blind, randomised and placebo-controlled trial.

C Wyatt M, Wright T, Locker J, Stout K, Chapple C, Theis JC.

Bone Joint Res. 2015 Feb;4(2):11-6. doi: 10.1302/2046-3758.42.2000329.

20.

Antibacterial validation of electrogenerated hypochlorite using carbon-based electrodes.

Locker J, Fitzgerald P, Sharp D.

Lett Appl Microbiol. 2014 Dec;59(6):636-41. doi: 10.1111/lam.12324. Epub 2014 Sep 26.

21.

Lung cancer transcriptomes refined with laser capture microdissection.

Lin J, Marquardt G, Mullapudi N, Wang T, Han W, Shi M, Keller S, Zhu C, Locker J, Spivack SD.

Am J Pathol. 2014 Nov;184(11):2868-84. doi: 10.1016/j.ajpath.2014.06.028. Epub 2014 Aug 14.

22.

A nonhuman primate model of human radiation-induced venocclusive liver disease and hepatocyte injury.

Yannam GR, Han B, Setoyama K, Yamamoto T, Ito R, Brooks JM, Guzman-Lepe J, Galambos C, Fong JV, Deutsch M, Quader MA, Yamanouchi K, Kabarriti R, Mehta K, Soto-Gutierrez A, Roy-Chowdhury J, Locker J, Abe M, Enke CA, Baranowska-Kortylewicz J, Solberg TD, Guha C, Fox IJ.

Int J Radiat Oncol Biol Phys. 2014 Feb 1;88(2):404-411. doi: 10.1016/j.ijrobp.2013.10.037. Epub 2013 Dec 5.

23.

Skp2 deletion unmasks a p27 safeguard that blocks tumorigenesis in the absence of pRb and p53 tumor suppressors.

Zhao H, Bauzon F, Fu H, Lu Z, Cui J, Nakayama K, Nakayama KI, Locker J, Zhu L.

Cancer Cell. 2013 Nov 11;24(5):645-59. doi: 10.1016/j.ccr.2013.09.021.

24.

Gadd45 in the liver: signal transduction and transcriptional mechanisms.

Tian J, Locker J.

Adv Exp Med Biol. 2013;793:69-80. doi: 10.1007/978-1-4614-8289-5_5. Review.

PMID:
24104474
25.

Repopulation of the fibrotic/cirrhotic rat liver by transplanted hepatic stem/progenitor cells and mature hepatocytes.

Yovchev MI, Xue Y, Shafritz DA, Locker J, Oertel M.

Hepatology. 2014 Jan;59(1):284-95. doi: 10.1002/hep.26615. Epub 2013 Nov 18.

26.

Cigarette craving and withdrawal symptoms during temporary abstinence and the effect of nicotine gum.

Brown J, Hajek P, McRobbie H, Locker J, Gillison F, McEwen A, Beard E, West R.

Psychopharmacology (Berl). 2013 Sep;229(1):209-18. doi: 10.1007/s00213-013-3100-2. Epub 2013 May 2.

PMID:
23636302
28.

ClpV recycles VipA/VipB tubules and prevents non-productive tubule formation to ensure efficient type VI protein secretion.

Kapitein N, Bönemann G, Pietrosiuk A, Seyffer F, Hausser I, Locker JK, Mogk A.

Mol Microbiol. 2013 Mar;87(5):1013-28. doi: 10.1111/mmi.12147. Epub 2013 Feb 3.

29.

Classifying collective cancer cell invasion.

Friedl P, Locker J, Sahai E, Segall JE.

Nat Cell Biol. 2012 Aug;14(8):777-83. doi: 10.1038/ncb2548. Review.

PMID:
22854810
30.

p21CIP1 mediates reciprocal switching between proliferation and invasion during metastasis.

Qian X, Hulit J, Suyama K, Eugenin EA, Belbin TJ, Loudig O, Smirnova T, Zhou ZN, Segall J, Locker J, Phillips GR, Norton L, Hazan RB.

Oncogene. 2013 May 2;32(18):2292-2303.e7. doi: 10.1038/onc.2012.249. Epub 2012 Jul 2.

31.

Very brief advice on smoking.

McEwen A, McIlvar M, Locker J.

Nurs Times. 2012 Feb 28-Mar 5;108(9):23. No abstract available.

PMID:
22479770
32.

Gadd45β is an inducible coactivator of transcription that facilitates rapid liver growth in mice.

Tian J, Huang H, Hoffman B, Liebermann DA, Ledda-Columbano GM, Columbano A, Locker J.

J Clin Invest. 2011 Nov;121(11):4491-502. doi: 10.1172/JCI38760. Epub 2011 Oct 3.

33.

Systematic targeted integration to study Albumin gene control elements.

Bhattacharyya S, Tian J, Bouhassira EE, Locker J.

PLoS One. 2011;6(8):e23234. doi: 10.1371/journal.pone.0023234. Epub 2011 Aug 12.

34.

In vivo invasion of head and neck squamous cell carcinoma cells does not require macrophages.

Smirnova T, Adomako A, Locker J, Van Rooijen N, Prystowsky MB, Segall JE.

Am J Pathol. 2011 Jun;178(6):2857-65. doi: 10.1016/j.ajpath.2011.02.030.

35.

Proteomic characterization of early changes induced by triiodothyronine in rat liver.

Severino V, Locker J, Ledda-Columbano GM, Columbano A, Parente A, Chambery A.

J Proteome Res. 2011 Jul 1;10(7):3212-24. doi: 10.1021/pr200244f. Epub 2011 Jun 1.

36.

Breast cancer: the matrix is the message.

Locker J, Segall JE.

Am J Pathol. 2011 Mar;178(3):966-8. doi: 10.1016/j.ajpath.2010.12.013. No abstract available.

37.

Expression of c-jun is not mandatory for mouse hepatocyte proliferation induced by two nuclear receptor ligands: TCPOBOP and T3.

Leoni VP, Ledda-Columbano GM, Pibiri M, Saliba C, Perra A, Kowalik MA, Grober OM, Ravo M, Weisz A, Locker J, Ghiso E, Giordano S, Columbano A.

J Hepatol. 2011 Nov;55(5):1069-78. doi: 10.1016/j.jhep.2011.02.016. Epub 2011 Feb 25.

38.

Both gene amplification and allelic loss occur at 14q13.3 in lung cancer.

Harris T, Pan Q, Sironi J, Lutz D, Tian J, Sapkar J, Perez-Soler R, Keller S, Locker J.

Clin Cancer Res. 2011 Feb 15;17(4):690-9. doi: 10.1158/1078-0432.CCR-10-1892. Epub 2010 Dec 10.

39.

Growth and metastases of human lung cancer are inhibited in mouse xenografts by a transition state analogue of 5'-methylthioadenosine phosphorylase.

Basu I, Locker J, Cassera MB, Belbin TJ, Merino EF, Dong X, Hemeon I, Evans GB, Guha C, Schramm VL.

J Biol Chem. 2011 Feb 11;286(6):4902-11. doi: 10.1074/jbc.M110.198374. Epub 2010 Dec 6.

40.

High pressure injection of silica-based paint into a finger.

Locker J, Carstens A.

N Z Med J. 2010 Jun 11;123(1316):104-6. No abstract available.

PMID:
20648104
41.

Hijacking cellular garbage cans.

Welsch S, Locker JK.

Cell Host Microbe. 2010 Jun 25;7(6):424-6. doi: 10.1016/j.chom.2010.05.014.

42.

Rare NRXN1 promoter variants in patients with schizophrenia.

Shah AK, Tioleco NM, Nolan K, Locker J, Groh K, Villa C, Stopkova P, Pedrosa E, Lachman HM.

Neurosci Lett. 2010 May 14;475(2):80-4. doi: 10.1016/j.neulet.2010.03.047. Epub 2010 Mar 25.

43.

Failure of postnatal ductus arteriosus closure in prostaglandin transporter-deficient mice.

Chang HY, Locker J, Lu R, Schuster VL.

Circulation. 2010 Feb 2;121(4):529-36. doi: 10.1161/CIRCULATIONAHA.109.862946. Epub 2010 Jan 18.

44.

Skp2 is required for survival of aberrantly proliferating Rb1-deficient cells and for tumorigenesis in Rb1+/- mice.

Wang H, Bauzon F, Ji P, Xu X, Sun D, Locker J, Sellers RS, Nakayama K, Nakayama KI, Cobrinik D, Zhu L.

Nat Genet. 2010 Jan;42(1):83-8. doi: 10.1038/ng.498. Epub 2009 Dec 6.

45.

Hypermethylation of the human proton-coupled folate transporter (SLC46A1) minimal transcriptional regulatory region in an antifolate-resistant HeLa cell line.

Diop-Bove NK, Wu J, Zhao R, Locker J, Goldman ID.

Mol Cancer Ther. 2009 Aug;8(8):2424-31. doi: 10.1158/1535-7163.MCT-08-0938. Epub 2009 Aug 11.

46.

Loss of retinal cadherin facilitates mammary tumor progression and metastasis.

Agiostratidou G, Li M, Suyama K, Badano I, Keren R, Chung S, Anzovino A, Hulit J, Qian B, Bouzahzah B, Eugenin E, Loudig O, Phillips GR, Locker J, Hazan RB.

Cancer Res. 2009 Jun 15;69(12):5030-8. doi: 10.1158/0008-5472.CAN-08-4007. Epub 2009 Jun 2.

47.

Survey of schizophrenia and bipolar disorder candidate genes using chromatin immunoprecipitation and tiled microarrays (ChIP-chip).

Pedrosa E, Locker J, Lachman HM.

J Neurogenet. 2009;23(3):341-52. doi: 10.1080/01677060802669766. Epub 2009 Feb 18.

PMID:
19225952
48.

Does the reaction of abstaining smokers to the smell of other people's cigarettes predict relapse?

McRobbie H, Hajek P, Locker J.

Addiction. 2008 Nov;103(11):1883-7. doi: 10.1111/j.1360-0443.2008.02340.x.

PMID:
19032537
49.

Structure and function of the virulence-associated high-temperature requirement A of Mycobacterium tuberculosis.

Mohamedmohaideen NN, Palaninathan SK, Morin PM, Williams BJ, Braunstein M, Tichy SE, Locker J, Russell DH, Jacobs WR Jr, Sacchettini JC.

Biochemistry. 2008 Jun 10;47(23):6092-102. doi: 10.1021/bi701929m. Epub 2008 May 15.

PMID:
18479146
50.

Triiodothyronine stimulates hepatocyte proliferation in two models of impaired liver regeneration.

Columbano A, Simbula M, Pibiri M, Perra A, Deidda M, Locker J, Pisanu A, Uccheddu A, Ledda-Columbano GM.

Cell Prolif. 2008 Jun;41(3):521-31. doi: 10.1111/j.1365-2184.2008.00532.x. Epub 2008 Apr 14.

PMID:
18422700

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