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Items: 21


Identification of the IL-33 protein segment that controls subcellular localization, extracellular secretion, and functional maturation.

Luzina IG, Clerman A, Fishelevich R, Todd NW, Lockatell V, Atamas SP.

Cytokine. 2019 Jul;119:1-6. doi: 10.1016/j.cyto.2019.02.015. Epub 2019 Mar 8.


The full-length interleukin-33 (FLIL33)-importin-5 interaction does not regulate nuclear localization of FLIL33 but controls its intracellular degradation.

Clerman A, Noor Z, Fishelevich R, Lockatell V, Hampton BS, Shah NG, Salcedo MV, Todd NW, Atamas SP, Luzina IG.

J Biol Chem. 2017 Dec 29;292(52):21653-21661. doi: 10.1074/jbc.M117.807636. Epub 2017 Nov 10.


Sirtuin 7 is decreased in pulmonary fibrosis and regulates the fibrotic phenotype of lung fibroblasts.

Wyman AE, Noor Z, Fishelevich R, Lockatell V, Shah NG, Todd NW, Atamas SP.

Am J Physiol Lung Cell Mol Physiol. 2017 Jun 1;312(6):L945-L958. doi: 10.1152/ajplung.00473.2016. Epub 2017 Apr 6.


Elevated expression of NEU1 sialidase in idiopathic pulmonary fibrosis provokes pulmonary collagen deposition, lymphocytosis, and fibrosis.

Luzina IG, Lockatell V, Hyun SW, Kopach P, Kang PH, Noor Z, Liu A, Lillehoj EP, Lee C, Miranda-Ribera A, Todd NW, Goldblum SE, Atamas SP.

Am J Physiol Lung Cell Mol Physiol. 2016 May 15;310(10):L940-54. doi: 10.1152/ajplung.00346.2015. Epub 2016 Mar 18.


Pharmacological In Vivo Inhibition of S-Nitrosoglutathione Reductase Attenuates Bleomycin-Induced Inflammation and Fibrosis.

Luzina IG, Lockatell V, Todd NW, Kopach P, Pentikis HS, Atamas SP.

J Pharmacol Exp Ther. 2015 Oct;355(1):13-22. doi: 10.1124/jpet.115.224675. Epub 2015 Jul 24.


IFN-γ directly controls IL-33 protein level through a STAT1- and LMP2-dependent mechanism.

Kopach P, Lockatell V, Pickering EM, Haskell RE, Anderson RD, Hasday JD, Todd NW, Luzina IG, Atamas SP.

J Biol Chem. 2014 Apr 25;289(17):11829-43. doi: 10.1074/jbc.M113.534396. Epub 2014 Mar 11.


Interleukin-33 potentiates bleomycin-induced lung injury.

Luzina IG, Kopach P, Lockatell V, Kang PH, Nagarsekar A, Burke AP, Hasday JD, Todd NW, Atamas SP.

Am J Respir Cell Mol Biol. 2013 Dec;49(6):999-1008. doi: 10.1165/rcmb.2013-0093OC.


Full-length IL-33 promotes inflammation but not Th2 response in vivo in an ST2-independent fashion.

Luzina IG, Pickering EM, Kopach P, Kang PH, Lockatell V, Todd NW, Papadimitriou JC, McKenzie AN, Atamas SP.

J Immunol. 2012 Jul 1;189(1):403-10. doi: 10.4049/jimmunol.1200259. Epub 2012 May 25.


Natural production and functional effects of alternatively spliced interleukin-4 protein in asthma.

Luzina IG, Lockatell V, Lavania S, Pickering EM, Kang PH, Bashkatova YN, Andreev SM, Atamas SP.

Cytokine. 2012 Apr;58(1):20-6. doi: 10.1016/j.cyto.2011.12.017. Epub 2012 Jan 15.


Alternatively spliced variants of interleukin-4 promote inflammation differentially.

Luzina IG, Lockatell V, Todd NW, Highsmith K, Keegan AD, Hasday JD, Atamas SP.

J Leukoc Biol. 2011 May;89(5):763-70. doi: 10.1189/jlb.0510271. Epub 2011 Feb 1.


Splice isoforms of human interleukin-4 are functionally active in mice in vivo.

Luzina IG, Lockatell V, Todd NW, Keegan AD, Hasday JD, Atamas SP.

Immunology. 2011 Mar;132(3):385-93. doi: 10.1111/j.1365-2567.2010.03393.x. Epub 2011 Jan 10.


Regulation of pulmonary inflammation and fibrosis through expression of integrins alphaVbeta3 and alphaVbeta5 on pulmonary T lymphocytes.

Luzina IG, Todd NW, Nacu N, Lockatell V, Choi J, Hummers LK, Atamas SP.

Arthritis Rheum. 2009 May;60(5):1530-9. doi: 10.1002/art.24435.


Macrophages produce TGF-beta-induced (beta-ig-h3) following ingestion of apoptotic cells and regulate MMP14 levels and collagen turnover in fibroblasts.

Nacu N, Luzina IG, Highsmith K, Lockatell V, Pochetuhen K, Cooper ZA, Gillmeister MP, Todd NW, Atamas SP.

J Immunol. 2008 Apr 1;180(7):5036-44.


Complex regulation of pulmonary inflammation and fibrosis by CCL18.

Pochetuhen K, Luzina IG, Lockatell V, Choi J, Todd NW, Atamas SP.

Am J Pathol. 2007 Aug;171(2):428-37. Epub 2007 Jun 14.


Role of motility in the colonization of uropathogenic Escherichia coli in the urinary tract.

Lane MC, Lockatell V, Monterosso G, Lamphier D, Weinert J, Hebel JR, Johnson DE, Mobley HL.

Infect Immun. 2005 Nov;73(11):7644-56.


Nicotinic acid limitation regulates silencing of Candida adhesins during UTI.

Domergue R, Castaño I, De Las Peñas A, Zupancic M, Lockatell V, Hebel JR, Johnson D, Cormack BP.

Science. 2005 May 6;308(5723):866-70. Epub 2005 Mar 17.


Assessment of virulence of uropathogenic Escherichia coli type 1 fimbrial mutants in which the invertible element is phase-locked on or off.

Gunther NW 4th, Snyder JA, Lockatell V, Blomfield I, Johnson DE, Mobley HL.

Infect Immun. 2002 Jul;70(7):3344-54.


In vivo dynamics of type 1 fimbria regulation in uropathogenic Escherichia coli during experimental urinary tract infection.

Gunther NW 4th, Lockatell V, Johnson DE, Mobley HL.

Infect Immun. 2001 May;69(5):2838-46.


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