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Items: 1 to 50 of 58

1.

Notch1 activates angiogenic regulator Netrin4 in endothelial cells.

Liu Q, Allen TD, Song W, Wada Y, Lobe CG, Liu J.

J Cell Mol Med. 2019 May;23(5):3762-3766. doi: 10.1111/jcmm.14240. Epub 2019 Feb 19.

2.

Unveiling resistance mechanisms to EGFR inhibitors in cholangiocarcinoma.

Vaquero J, Lobe C, Fouassier L.

Oncotarget. 2018 Dec 18;9(99):37274-37275. doi: 10.18632/oncotarget.26403. eCollection 2018 Dec 18. No abstract available.

3.

The IGF2/IR/IGF1R Pathway in Tumor Cells and Myofibroblasts Mediates Resistance to EGFR Inhibition in Cholangiocarcinoma.

Vaquero J, Lobe C, Tahraoui S, Clapéron A, Mergey M, Merabtene F, Wendum D, Coulouarn C, Housset C, Desbois-Mouthon C, Praz F, Fouassier L.

Clin Cancer Res. 2018 Sep 1;24(17):4282-4296. doi: 10.1158/1078-0432.CCR-17-3725. Epub 2018 May 1.

PMID:
29716918
4.

The role of Notch signalling in ovarian angiogenesis.

Xie Q, Cheng Z, Chen X, Lobe CG, Liu J.

J Ovarian Res. 2017 Mar 11;10(1):13. doi: 10.1186/s13048-017-0308-5. Review.

5.

Overexpression of Fibrinogen-Like Protein 2 Promotes Tolerance in a Fully Mismatched Murine Model of Heart Transplantation.

Bartczak A, Chruscinski A, Mendicino M, Liu H, Zhang J, He W, Amir AZ, Nguyen A, Khattar R, Sadozai H, Lobe CG, Adeyi O, Phillips MJ, Zhang L, Gorczynski RM, Grant D, Levy GA.

Am J Transplant. 2016 Jun;16(6):1739-50. doi: 10.1111/ajt.13696. Epub 2016 Mar 17.

6.

Catalpol downregulates vascular endothelial‑cadherin expression and induces vascular hyperpermeability.

Zhang C, Liu Q, Dong F, Li L, Du J, Xie Q, Hu H, Yan S, Zhou X, Li C, Lobe CG, Liu J.

Mol Med Rep. 2016 Jan;13(1):373-8. doi: 10.3892/mmr.2015.4522. Epub 2015 Nov 6.

PMID:
26549479
7.

Trichostatin A suppresses lung adenocarcinoma development in Grg1 overexpressing transgenic mice.

Liu J, Li Y, Dong F, Li L, Masuda T, Allen TD, Lobe CG.

Biochem Biophys Res Commun. 2015 Aug 7;463(4):1230-6. doi: 10.1016/j.bbrc.2015.06.090. Epub 2015 Jun 15.

PMID:
26086099
8.

Short-term, low-dose cadmium exposure induces hyperpermeability in human renal glomerular endothelial cells.

Li L, Dong F, Xu D, Du L, Yan S, Hu H, Lobe CG, Yi F, Kapron CM, Liu J.

J Appl Toxicol. 2016 Feb;36(2):257-65. doi: 10.1002/jat.3168. Epub 2015 May 25.

PMID:
26011702
9.

CCR5 facilitates endothelial progenitor cell recruitment and promotes the stabilization of atherosclerotic plaques in ApoE-/- mice.

Zhang Z, Dong J, Lobe CG, Gong P, Liu J, Liao L.

Stem Cell Res Ther. 2015 Mar 19;6:36. doi: 10.1186/s13287-015-0026-0.

10.
11.

Postnatal Notch1 activation induces T‑cell malignancy in conditional and inducible mouse models.

Liu J, Dong F, Fung I, Chen E, Allen TD, Deutsch U, Lobe CG.

Int J Oncol. 2014 Nov;45(5):1997-2004. doi: 10.3892/ijo.2014.2626. Epub 2014 Aug 29.

PMID:
25175815
12.

Constitutively active Notch1 signaling promotes endothelial‑mesenchymal transition in a conditional transgenic mouse model.

Liu J, Dong F, Jeong J, Masuda T, Lobe CG.

Int J Mol Med. 2014 Sep;34(3):669-76. doi: 10.3892/ijmm.2014.1818. Epub 2014 Jun 24.

13.

Constitutive notch signaling in adult transgenic mice inhibits bFGF-induced angiogenesis and blocks ovarian follicle development.

Liu J, Deutsch U, Jeong J, Lobe CG.

Genesis. 2014 Sep;52(9):809-16. doi: 10.1002/dvg.22790. Epub 2014 May 29.

PMID:
24817584
14.

Initially disadvantaged, TEL-AML1 cells expand and initiate leukemia in response to irradiation and cooperating mutations.

Li M, Jones L, Gaillard C, Binnewies M, Ochoa R, Garcia E, Lam V, Wei G, Yang W, Lobe C, Hermiston M, Passegué E, Kogan SC.

Leukemia. 2013 Jul;27(7):1570-3. doi: 10.1038/leu.2013.15. Epub 2013 Jan 16. No abstract available.

15.

Zonadhesin is essential for species specificity of sperm adhesion to the egg zona pellucida.

Tardif S, Wilson MD, Wagner R, Hunt P, Gertsenstein M, Nagy A, Lobe C, Koop BF, Hardy DM.

J Biol Chem. 2010 Aug 6;285(32):24863-70. doi: 10.1074/jbc.M110.123125. Epub 2010 Jun 7.

16.

Genomic localization of the Z/EG transgene in the mouse genome.

Colombo S, Kumasaka M, Lobe C, Larue L.

Genesis. 2010 Feb;48(2):96-100. doi: 10.1002/dvg.20585.

PMID:
20014334
17.

Ectopic notch activation in developing podocytes causes glomerulosclerosis.

Waters AM, Wu MY, Onay T, Scutaru J, Liu J, Lobe CG, Quaggin SE, Piscione TD.

J Am Soc Nephrol. 2008 Jun;19(6):1139-57. doi: 10.1681/ASN.2007050596. Epub 2008 Mar 12.

18.

ARS2 is a conserved eukaryotic gene essential for early mammalian development.

Wilson MD, Wang D, Wagner R, Breyssens H, Gertsenstein M, Lobe C, Lu X, Nagy A, Burke RD, Koop BF, Howard PL.

Mol Cell Biol. 2008 Mar;28(5):1503-14. Epub 2007 Dec 17.

19.
20.
21.

Grg1 acts as a lung-specific oncogene in a transgenic mouse model.

Allen T, van Tuyl M, Iyengar P, Jothy S, Post M, Tsao MS, Lobe CG.

Cancer Res. 2006 Feb 1;66(3):1294-301.

22.

Glypican-3 promotes the growth of hepatocellular carcinoma by stimulating canonical Wnt signaling.

Capurro MI, Xiang YY, Lobe C, Filmus J.

Cancer Res. 2005 Jul 15;65(14):6245-54.

23.

Hepatic vascular tumors, angiectasis in multiple organs, and impaired spermatogenesis in mice with conditional inactivation of the VHL gene.

Ma W, Tessarollo L, Hong SB, Baba M, Southon E, Back TC, Spence S, Lobe CG, Sharma N, Maher GW, Pack S, Vortmeyer AO, Guo C, Zbar B, Schmidt LS.

Cancer Res. 2003 Sep 1;63(17):5320-8.

24.

Contrasting effects of VEGF gene disruption in embryonic stem cell-derived versus oncogene-induced tumors.

Viloria-Petit A, Miquerol L, Yu JL, Gertsenstein M, Sheehan C, May L, Henkin J, Lobe C, Nagy A, Kerbel RS, Rak J.

EMBO J. 2003 Aug 15;22(16):4091-102.

25.

Genetic evidence that relative synaptic efficacy biases the outcome of synaptic competition.

Buffelli M, Burgess RW, Feng G, Lobe CG, Lichtman JW, Sanes JR.

Nature. 2003 Jul 24;424(6947):430-4.

PMID:
12879071
26.

The post-natal heart contains a myocardial stem cell population.

Hierlihy AM, Seale P, Lobe CG, Rudnicki MA, Megeney LA.

FEBS Lett. 2002 Oct 23;530(1-3):239-43.

27.

Early restriction of peripheral and proximal cell lineages during formation of the lung.

Perl AK, Wert SE, Nagy A, Lobe CG, Whitsett JA.

Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10482-7. Epub 2002 Jul 26.

28.

Expression of Cre Recombinase in the developing mouse limb bud driven by a Prxl enhancer.

Logan M, Martin JF, Nagy A, Lobe C, Olson EN, Tabin CJ.

Genesis. 2002 Jun;33(2):77-80.

PMID:
12112875
29.

A Cre recombinase transgene with mosaic, widespread tamoxifen-inducible action.

Guo C, Yang W, Lobe CG.

Genesis. 2002 Jan;32(1):8-18.

PMID:
11835669
30.

Reporter genes to detect Cre excision in mice.

Lobe CP, Guo C.

Curr Protoc Toxicol. 2002 Feb;Chapter 15:Unit15.4. doi: 10.1002/0471140856.tx1504s10.

PMID:
23045076
31.

Aggregation chimeras (ES cell-embryo).

Lobe CG, Guo C.

Curr Protoc Toxicol. 2002 Feb;Chapter 15:Unit15.3. doi: 10.1002/0471140856.tx1503s10.

PMID:
23045075
32.

ES cell-mediated conditional transgenesis.

Gertsenstein M, Lobe C, Nagy A.

Methods Mol Biol. 2002;185:285-307. Review. No abstract available.

PMID:
11768997
33.

Z/EG, a double reporter mouse line that expresses enhanced green fluorescent protein upon Cre-mediated excision.

Novak A, Guo C, Yang W, Nagy A, Lobe CG.

Genesis. 2000 Nov-Dec;28(3-4):147-55.

PMID:
11105057
34.

Targeted insertion of Cre recombinase into the TNAP gene: excision in primordial germ cells.

Lomelí H, Ramos-Mejía V, Gertsenstein M, Lobe CG, Nagy A.

Genesis. 2000 Feb;26(2):116-7. No abstract available.

PMID:
10686602
35.

A comparison of Notch, Hes and Grg expression during murine embryonic and post-natal development.

Allen T, Lobe CG.

Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):687-708.

PMID:
10512199
36.

Z/AP, a double reporter for cre-mediated recombination.

Lobe CG, Koop KE, Kreppner W, Lomeli H, Gertsenstein M, Nagy A.

Dev Biol. 1999 Apr 15;208(2):281-92.

37.

Conditional genome alteration in mice.

Lobe CG, Nagy A.

Bioessays. 1998 Mar;20(3):200-8. Review.

PMID:
9631647
40.
42.

Activation of Hox gene expression by Hoxa-5.

Lobe CG.

DNA Cell Biol. 1995 Oct;14(10):817-23.

PMID:
7546287
43.
44.

Transcription factors and mammalian development.

Lobe CG.

Curr Top Dev Biol. 1992;27:351-83. Review. No abstract available.

PMID:
1424766
45.
46.

Transcriptional regulation of two cytotoxic T lymphocyte-specific serine protease genes.

Lobe CG, Shaw J, Fregeau C, Duggan B, Meier M, Brewer A, Upton C, McFadden G, Patient RK, Paetkau V, et al.

Nucleic Acids Res. 1989 Jul 25;17(14):5765-79.

47.

IL-2 induces expression of serine protease enzymes and genes in natural killer and nonspecific T killer cells.

Manyak CL, Norton GP, Lobe CG, Bleackley RC, Gershenfeld HK, Weissman IL, Kumar V, Sigal NH, Koo GC.

J Immunol. 1989 May 15;142(10):3707-13.

PMID:
2785561
48.

Organization of two genes encoding cytotoxic T lymphocyte-specific serine proteases CCPI and CCPII.

Lobe CG, Upton C, Duggan B, Ehrman N, Letellier M, Bell J, McFadden G, Bleackley RC.

Biochemistry. 1988 Sep 6;27(18):6941-6.

PMID:
3264185
49.

Isolation of two cDNA sequences which encode cytotoxic cell proteases.

Bleackley RC, Duggan B, Ehrman N, Lobe CG.

FEBS Lett. 1988 Jul 4;234(1):153-9.

50.

Expression of two serine esterase genes during an allograft rejection in the mouse.

Mueller C, Gershenfeld HK, Lobe CG, Okada CY, Bleackley RC, Weissman IL.

Transplant Proc. 1988 Apr;20(2):251-3. No abstract available.

PMID:
3363633

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