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Items: 22

1.

Imaging-assisted nanoimmunotherapy for atherosclerosis in multiple species.

Binderup T, Duivenvoorden R, Fay F, van Leent MMT, Malkus J, Baxter S, Ishino S, Zhao Y, Sanchez-Gaytan B, Teunissen AJP, Frederico YCA, Tang J, Carlucci G, Lyashchenko S, Calcagno C, Karakatsanis N, Soultanidis G, Senders ML, Robson PM, Mani V, Ramachandran S, Lobatto ME, Hutten BA, Granada JF, Reiner T, Swirski FK, Nahrendorf M, Kjaer A, Fisher EA, Fayad ZA, Pérez-Medina C, Mulder WJM.

Sci Transl Med. 2019 Aug 21;11(506). pii: eaaw7736. doi: 10.1126/scitranslmed.aaw7736.

PMID:
31434756
2.

Multimodal Positron Emission Tomography Imaging to Quantify Uptake of 89Zr-Labeled Liposomes in the Atherosclerotic Vessel Wall.

Lobatto ME, Binderup T, Robson PM, Giesen LFP, Calcagno C, Witjes J, Fay F, Baxter S, Wessel CH, Eldib M, Bini J, Carlin SD, Stroes ESG, Storm G, Kjaer A, Lewis JS, Reiner T, Fayad ZA, Mulder WJM, Pérez-Medina C.

Bioconjug Chem. 2019 Jun 7. doi: 10.1021/acs.bioconjchem.9b00256. [Epub ahead of print]

PMID:
31095372
3.

Nanobody-Facilitated Multiparametric PET/MRI Phenotyping of Atherosclerosis.

Senders ML, Hernot S, Carlucci G, van de Voort JC, Fay F, Calcagno C, Tang J, Alaarg A, Zhao Y, Ishino S, Palmisano A, Boeykens G, Meerwaldt AE, Sanchez-Gaytan BL, Baxter S, Zendman L, Lobatto ME, Karakatsanis NA, Robson PM, Broisat A, Raes G, Lewis JS, Tsimikas S, Reiner T, Fayad ZA, Devoogdt N, Mulder WJM, Pérez-Medina C.

JACC Cardiovasc Imaging. 2019 Oct;12(10):2015-2026. doi: 10.1016/j.jcmg.2018.07.027. Epub 2018 Oct 17.

4.

Development and Multiparametric Evaluation of Experimental Atherosclerosis in Rabbits.

Senders ML, Lobatto ME, Soler R, Lairez O, Pérez-Medina C, Calcagno C, Fayad ZA, Mulder WJM, Fay F.

Methods Mol Biol. 2018;1816:385-400. doi: 10.1007/978-1-4939-8597-5_30.

PMID:
29987836
5.

PET/MR Imaging of Malondialdehyde-Acetaldehyde Epitopes With a Human Antibody Detects Clinically Relevant Atherothrombosis.

Senders ML, Que X, Cho YS, Yeang C, Groenen H, Fay F, Calcagno C, Meerwaldt AE, Green S, Miu P, Lobatto ME, Reiner T, Fayad ZA, Witztum JL, Mulder WJM, Pérez-Medina C, Tsimikas S.

J Am Coll Cardiol. 2018 Jan 23;71(3):321-335. doi: 10.1016/j.jacc.2017.11.036.

6.

In Vivo PET Imaging of HDL in Multiple Atherosclerosis Models.

Pérez-Medina C, Binderup T, Lobatto ME, Tang J, Calcagno C, Giesen L, Wessel CH, Witjes J, Ishino S, Baxter S, Zhao Y, Ramachandran S, Eldib M, Sánchez-Gaytán BL, Robson PM, Bini J, Granada JF, Fish KM, Stroes ES, Duivenvoorden R, Tsimikas S, Lewis JS, Reiner T, Fuster V, Kjær A, Fisher EA, Fayad ZA, Mulder WJ.

JACC Cardiovasc Imaging. 2016 Aug;9(8):950-61. doi: 10.1016/j.jcmg.2016.01.020. Epub 2016 May 25.

7.

Three-dimensional dynamic contrast-enhanced MRI for the accurate, extensive quantification of microvascular permeability in atherosclerotic plaques.

Calcagno C, Lobatto ME, Dyvorne H, Robson PM, Millon A, Senders ML, Lairez O, Ramachandran S, Coolen BF, Black A, Mulder WJ, Fayad ZA.

NMR Biomed. 2015 Oct;28(10):1304-14. doi: 10.1002/nbm.3369. Epub 2015 Aug 30.

8.

Inhibiting macrophage proliferation suppresses atherosclerotic plaque inflammation.

Tang J, Lobatto ME, Hassing L, van der Staay S, van Rijs SM, Calcagno C, Braza MS, Baxter S, Fay F, Sanchez-Gaytan BL, Duivenvoorden R, Sager H, Astudillo YM, Leong W, Ramachandran S, Storm G, Pérez-Medina C, Reiner T, Cormode DP, Strijkers GJ, Stroes ES, Swirski FK, Nahrendorf M, Fisher EA, Fayad ZA, Mulder WJ.

Sci Adv. 2015 Apr;1(3). pii: e1400223.

9.

Prednisolone-containing liposomes accumulate in human atherosclerotic macrophages upon intravenous administration.

van der Valk FM, van Wijk DF, Lobatto ME, Verberne HJ, Storm G, Willems MC, Legemate DA, Nederveen AJ, Calcagno C, Mani V, Ramachandran S, Paridaans MP, Otten MJ, Dallinga-Thie GM, Fayad ZA, Nieuwdorp M, Schulte DM, Metselaar JM, Mulder WJ, Stroes ES.

Nanomedicine. 2015 Jul;11(5):1039-46. doi: 10.1016/j.nano.2015.02.021. Epub 2015 Mar 17.

10.

Pharmaceutical development and preclinical evaluation of a GMP-grade anti-inflammatory nanotherapy.

Lobatto ME, Calcagno C, Otten MJ, Millon A, Ramachandran S, Paridaans MP, van der Valk FM, Storm G, Stroes ES, Fayad ZA, Mulder WJ, Metselaar JM.

Nanomedicine. 2015 Jul;11(5):1133-40. doi: 10.1016/j.nano.2015.02.020. Epub 2015 Mar 17.

11.

HDL-mimetic PLGA nanoparticle to target atherosclerosis plaque macrophages.

Sanchez-Gaytan BL, Fay F, Lobatto ME, Tang J, Ouimet M, Kim Y, van der Staay SE, van Rijs SM, Priem B, Zhang L, Fisher EA, Moore KJ, Langer R, Fayad ZA, Mulder WJ.

Bioconjug Chem. 2015 Mar 18;26(3):443-51. doi: 10.1021/bc500517k. Epub 2015 Feb 13.

12.

Atherosclerotic plaque targeting mechanism of long-circulating nanoparticles established by multimodal imaging.

Lobatto ME, Calcagno C, Millon A, Senders ML, Fay F, Robson PM, Ramachandran S, Binderup T, Paridaans MP, Sensarn S, Rogalla S, Gordon RE, Cardoso L, Storm G, Metselaar JM, Contag CH, Stroes ES, Fayad ZA, Mulder WJ.

ACS Nano. 2015 Feb 24;9(2):1837-47. doi: 10.1021/nn506750r. Epub 2015 Jan 28.

13.

Nonpharmacological lipoprotein apheresis reduces arterial inflammation in familial hypercholesterolemia.

van Wijk DF, Sjouke B, Figueroa A, Emami H, van der Valk FM, MacNabb MH, Hemphill LC, Schulte DM, Koopman MG, Lobatto ME, Verberne HJ, Fayad ZA, Kastelein JJ, Mulder WJ, Hovingh GK, Tawakol A, Stroes ES.

J Am Coll Cardiol. 2014 Oct 7;64(14):1418-26. doi: 10.1016/j.jacc.2014.01.088.

14.

A statin-loaded reconstituted high-density lipoprotein nanoparticle inhibits atherosclerotic plaque inflammation.

Duivenvoorden R, Tang J, Cormode DP, Mieszawska AJ, Izquierdo-Garcia D, Ozcan C, Otten MJ, Zaidi N, Lobatto ME, van Rijs SM, Priem B, Kuan EL, Martel C, Hewing B, Sager H, Nahrendorf M, Randolph GJ, Stroes ES, Fuster V, Fisher EA, Fayad ZA, Mulder WJ.

Nat Commun. 2014;5:3065. doi: 10.1038/ncomms4065. Erratum in: Nat Commun. 2014;5:3531.

15.

Probing nanoparticle translocation across the permeable endothelium in experimental atherosclerosis.

Kim Y, Lobatto ME, Kawahara T, Lee Chung B, Mieszawska AJ, Sanchez-Gaytan BL, Fay F, Senders ML, Calcagno C, Becraft J, Tun Saung M, Gordon RE, Stroes ES, Ma M, Farokhzad OC, Fayad ZA, Mulder WJ, Langer R.

Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):1078-83. doi: 10.1073/pnas.1322725111. Epub 2014 Jan 6.

16.

Imaging the efficacy of anti-inflammatory liposomes in a rabbit model of atherosclerosis by non-invasive imaging.

Lobatto ME, Calcagno C, Metselaar JM, Storm G, Stroes ES, Fayad ZA, Mulder WJ.

Methods Enzymol. 2012;508:211-28. doi: 10.1016/B978-0-12-391860-4.00011-2.

17.

Nanomedical Theranostics in Cardiovascular Disease.

Tang J, Lobatto ME, Read JC, Mieszawska AJ, Fayad ZA, Mulder WJ.

Curr Cardiovasc Imaging Rep. 2012 Feb;5(1):19-25. Epub 2011 Nov 29.

18.

In vivo characterization of a new abdominal aortic aneurysm mouse model with conventional and molecular magnetic resonance imaging.

Klink A, Heynens J, Herranz B, Lobatto ME, Arias T, Sanders HM, Strijkers GJ, Merkx M, Nicolay K, Fuster V, Tedgui A, Mallat Z, Mulder WJ, Fayad ZA.

J Am Coll Cardiol. 2011 Dec 6;58(24):2522-30. doi: 10.1016/j.jacc.2011.09.017.

19.

Perspectives and opportunities for nanomedicine in the management of atherosclerosis.

Lobatto ME, Fuster V, Fayad ZA, Mulder WJ.

Nat Rev Drug Discov. 2011 Oct 21;10(11):835-52. doi: 10.1038/nrd3578. Review. Erratum in: Nat Rev Drug Discov. 2011 Dec;10(12):963.

20.

Multimodal clinical imaging to longitudinally assess a nanomedical anti-inflammatory treatment in experimental atherosclerosis.

Lobatto ME, Fayad ZA, Silvera S, Vucic E, Calcagno C, Mani V, Dickson SD, Nicolay K, Banciu M, Schiffelers RM, Metselaar JM, van Bloois L, Wu HS, Fallon JT, Rudd JH, Fuster V, Fisher EA, Storm G, Mulder WJ.

Mol Pharm. 2010 Dec 6;7(6):2020-9. doi: 10.1021/mp100309y. Epub 2010 Nov 8.

21.

Nanocrystal core high-density lipoproteins: a multimodality contrast agent platform.

Cormode DP, Skajaa T, van Schooneveld MM, Koole R, Jarzyna P, Lobatto ME, Calcagno C, Barazza A, Gordon RE, Zanzonico P, Fisher EA, Fayad ZA, Mulder WJ.

Nano Lett. 2008 Nov;8(11):3715-23. doi: 10.1021/nl801958b. Epub 2008 Oct 22.

22.

Multimodality nanotracers for cardiovascular applications.

Mulder WJ, Cormode DP, Hak S, Lobatto ME, Silvera S, Fayad ZA.

Nat Clin Pract Cardiovasc Med. 2008 Aug;5 Suppl 2:S103-11. doi: 10.1038/ncpcardio1242. Review.

PMID:
18641599

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