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HBx-K130M/V131I Promotes Liver Cancer in Transgenic Mice via AKT/FOXO1 Signaling Pathway and Arachidonic Acid Metabolism.

Chiu AP, Tschida BR, Sham TT, Lo LH, Moriarity BS, Li XX, Lo RC, Hinton DE, Rowlands DK, Chan CO, Mok DKW, Largaespada DA, Warner N, Keng VW.

Mol Cancer Res. 2019 Jul;17(7):1582-1593. doi: 10.1158/1541-7786.MCR-18-1127. Epub 2019 Apr 11.


Deregulated GATA6 modulates stem cell-like properties and metabolic phenotype in hepatocellular carcinoma.

Tan HW, Leung CO, Chan KK, Ho DW, Leung MS, Wong CM, Ng IO, Lo RC.

Int J Cancer. 2019 Oct 1;145(7):1860-1873. doi: 10.1002/ijc.32248. Epub 2019 Mar 28.


In-hospital versus postdischarge major adverse events within 30 days following lower extremity revascularization.

Liang P, Li C, O'Donnell TFX, Lo RC, Soden PA, Swerdlow NJ, Schermerhorn ML.

J Vasc Surg. 2019 Feb;69(2):482-489. doi: 10.1016/j.jvs.2018.06.207. Epub 2018 Oct 6.


IRAK1 Augments Cancer Stemness and Drug Resistance via the AP-1/AKR1B10 Signaling Cascade in Hepatocellular Carcinoma.

Cheng BY, Lau EY, Leung HW, Leung CO, Ho NP, Gurung S, Cheng LK, Lin CH, Lo RC, Ma S, Ng IO, Lee TK.

Cancer Res. 2018 May 1;78(9):2332-2342. doi: 10.1158/0008-5472.CAN-17-2445. Epub 2018 Feb 26.


Cripto-1 contributes to stemness in hepatocellular carcinoma by stabilizing Dishevelled-3 and activating Wnt/β-catenin pathway.

Lo RC, Leung CO, Chan KK, Ho DW, Wong CM, Lee TK, Ng IO.

Cell Death Differ. 2018 Aug;25(8):1426-1441. doi: 10.1038/s41418-018-0059-x. Epub 2018 Feb 14.


Deregulation of Frizzled Receptors in Hepatocellular Carcinoma.

Chan KK, Lo RC.

Int J Mol Sci. 2018 Jan 21;19(1). pii: E313. doi: 10.3390/ijms19010313. Review.


Expression of hepatic progenitor cell markers in acute cellular rejection of liver allografts-An immunohistochemical study.

Lo RC, Chan KK, Leung CO, Ng IO.

Clin Transplant. 2018 Mar;32(3):e13203. doi: 10.1111/ctr.13203. Epub 2018 Feb 2.


Histopathological evaluation of liver fibrosis and cirrhosis regression.

Lo RC, Kim H.

Clin Mol Hepatol. 2017 Dec;23(4):302-307. doi: 10.3350/cmh.2017.0078. Epub 2017 Dec 20. Review.


Nuclear Met promotes hepatocellular carcinoma tumorigenesis and metastasis by upregulation of TAK1 and activation of NF-κB pathway.

Tey SK, Tse EYT, Mao X, Ko FCF, Wong AST, Lo RC, Ng IO, Yam JWP.

Cancer Lett. 2017 Dec 28;411:150-161. doi: 10.1016/j.canlet.2017.09.047. Epub 2017 Oct 6.


Liver allograft biopsies with histological cholestasis: a clinicopathological study of 254 cases from a single centre.

Lo RC, Chan KK, Chok KS, Ng IO.

J Clin Pathol. 2018 Jan;71(1):72-78. doi: 10.1136/jclinpath-2017-204334. Epub 2017 Jul 27.


Secretory Stanniocalcin 1 promotes metastasis of hepatocellular carcinoma through activation of JNK signaling pathway.

Chan KK, Leung CO, Wong CC, Ho DW, Chok KS, Lai CL, Ng IO, Lo RC.

Cancer Lett. 2017 Sep 10;403:330-338. doi: 10.1016/j.canlet.2017.06.034. Epub 2017 Jul 6.


Stearoyl-CoA desaturase regulates sorafenib resistance via modulation of ER stress-induced differentiation.

Ma MKF, Lau EYT, Leung DHW, Lo J, Ho NPY, Cheng LKW, Ma S, Lin CH, Copland JA, Ding J, Lo RCL, Ng IOL, Lee TKW.

J Hepatol. 2017 Nov;67(5):979-990. doi: 10.1016/j.jhep.2017.06.015. Epub 2017 Jun 22.


Trends in Treatment and Mortality for Mesenteric Ischemia in the United States from 2000 to 2012.

Zettervall SL, Lo RC, Soden PA, Deery SE, Ultee KH, Pinto DS, Wyers MC, Schermerhorn ML.

Ann Vasc Surg. 2017 Jul;42:111-119. doi: 10.1016/j.avsg.2017.01.007. Epub 2017 Mar 28.


SENP1 promotes hypoxia-induced cancer stemness by HIF-1α deSUMOylation and SENP1/HIF-1α positive feedback loop.

Cui CP, Wong CC, Kai AK, Ho DW, Lau EY, Tsui YM, Chan LK, Cheung TT, Chok KS, Chan ACY, Lo RC, Lee JM, Lee TK, Ng IOL.

Gut. 2017 Dec;66(12):2149-2159. doi: 10.1136/gutjnl-2016-313264. Epub 2017 Mar 3.


Sex differences in mortality and morbidity following repair of intact abdominal aortic aneurysms.

Deery SE, Soden PA, Zettervall SL, Shean KE, Bodewes TCF, Pothof AB, Lo RC, Schermerhorn ML.

J Vasc Surg. 2017 Apr;65(4):1006-1013. doi: 10.1016/j.jvs.2016.08.100. Epub 2016 Dec 13. Erratum in: J Vasc Surg. 2017 Jun;65(6):1874.


Mechanisms through Which Hypoxia-Induced Caveolin-1 Drives Tumorigenesis and Metastasis in Hepatocellular Carcinoma.

Mao X, Wong SY, Tse EY, Ko FC, Tey SK, Yeung YS, Man K, Lo RC, Ng IO, Yam JW.

Cancer Res. 2016 Dec 15;76(24):7242-7253. Epub 2016 Oct 26.


Molecular Pathogenesis of Hepatocellular Carcinoma.

Ho DW, Lo RC, Chan LK, Ng IO.

Liver Cancer. 2016 Oct;5(4):290-302. Epub 2016 Sep 14.


Hypoxia induces myeloid-derived suppressor cell recruitment to hepatocellular carcinoma through chemokine (C-C motif) ligand 26.

Chiu DK, Xu IM, Lai RK, Tse AP, Wei LL, Koh HY, Li LL, Lee D, Lo RC, Wong CM, Ng IO, Wong CC.

Hepatology. 2016 Sep;64(3):797-813. doi: 10.1002/hep.28655. Epub 2016 Jun 30.


Sox9 confers stemness properties in hepatocellular carcinoma through Frizzled-7 mediated Wnt/β-catenin signaling.

Leung CO, Mak WN, Kai AK, Chan KS, Lee TK, Ng IO, Lo RC.

Oncotarget. 2016 May 17;7(20):29371-86. doi: 10.18632/oncotarget.8835.


Liver metastasis of meningeal hemangiopericytoma: a study of 5 cases.

Lo RC, Suriawinata AA, Rubin BP.

Clin Mol Hepatol. 2016 Mar;22(1):188-91. doi: 10.3350/cmh.2016.22.1.188.


Down-regulation of TIMP2 by HIF-1α/miR-210/HIF-3α regulatory feedback circuit enhances cancer metastasis in hepatocellular carcinoma.

Kai AK, Chan LK, Lo RC, Lee JM, Wong CC, Wong JC, Ng IO.

Hepatology. 2016 Aug;64(2):473-87. doi: 10.1002/hep.28577. Epub 2016 Apr 30.


Arginine Metabolism in Bacterial Pathogenesis and Cancer Therapy.

Xiong L, Teng JL, Botelho MG, Lo RC, Lau SK, Woo PC.

Int J Mol Sci. 2016 Mar 11;17(3):363. doi: 10.3390/ijms17030363. Review.


Risk factors and consequences of persistent type II endoleaks.

Lo RC, Buck DB, Herrmann J, Hamdan AD, Wyers M, Patel VI, Fillinger M, Schermerhorn ML; Vascular Study Group of New England.

J Vasc Surg. 2016 Apr;63(4):895-901. doi: 10.1016/j.jvs.2015.10.088. Epub 2016 Jan 12.


Abdominal aortic aneurysms in women.

Lo RC, Schermerhorn ML.

J Vasc Surg. 2016 Mar;63(3):839-44. doi: 10.1016/j.jvs.2015.10.087. Epub 2015 Dec 30. Review.


Phosphorylation of nucleophosmin at threonine 234/237 is associated with HCC metastasis.

Ching RH, Lau EY, Ling PM, Lee JM, Ma MK, Cheng BY, Lo RC, Ng IO, Lee TK.

Oncotarget. 2015 Dec 22;6(41):43483-95. doi: 10.18632/oncotarget.5820.


Performance evaluation of the section of 3D reconstruction based on different PET/CT image fusion sequence.

Lo RC, Huang WL, Hsiao YL.

Technol Health Care. 2015;24 Suppl 1:S357-67. doi: 10.3233/THC-151093.


Rare cause of jaundice in a post liver transplant patient.

She WH, Chok KS, Lo RC, Chan SC, Lo CM.

Transpl Infect Dis. 2015 Aug;17(4):579-82. doi: 10.1111/tid.12414. Epub 2015 Jul 16.


IgG4-Related Hypertrophic Pachymeningitis at the Falx Cerebrii with Brain Parenchymal Invasion: A Case Report.

Li LF, Tse PY, Tsang FC, Lo RC, Lui WM, Leung GK.

World Neurosurg. 2015 Aug;84(2):591.e7-10. doi: 10.1016/j.wneu.2015.03.035. Epub 2015 Mar 30.


PIM1 regulates glycolysis and promotes tumor progression in hepatocellular carcinoma.

Leung CO, Wong CC, Fan DN, Kai AK, Tung EK, Xu IM, Ng IO, Lo RC.

Oncotarget. 2015 May 10;6(13):10880-92.


Evaluation of bile reflux in HIDA images based on fluid mechanics.

Lo RC, Huang WL, Fan YM.

Comput Biol Med. 2015 May;60:51-65. doi: 10.1016/j.compbiomed.2015.02.002. Epub 2015 Feb 24.


Switching of pyruvate kinase isoform L to M2 promotes metabolic reprogramming in hepatocarcinogenesis.

Wong CC, Au SL, Tse AP, Xu IM, Lai RK, Chiu DK, Wei LL, Fan DN, Tsang FH, Lo RC, Wong CM, Ng IO.

PLoS One. 2014 Dec 26;9(12):e115036. doi: 10.1371/journal.pone.0115036. eCollection 2014.


Routine use of ultrasound-guided access reduces access site-related complications after lower extremity percutaneous revascularization.

Lo RC, Fokkema MT, Curran T, Darling J, Hamdan AD, Wyers M, Martin M, Schermerhorn ML.

J Vasc Surg. 2015 Feb;61(2):405-12. doi: 10.1016/j.jvs.2014.07.099. Epub 2014 Sep 18.


Lysyl oxidase-like 2 is critical to tumor microenvironment and metastatic niche formation in hepatocellular carcinoma.

Wong CC, Tse AP, Huang YP, Zhu YT, Chiu DK, Lai RK, Au SL, Kai AK, Lee JM, Wei LL, Tsang FH, Lo RC, Shi J, Zheng YP, Wong CM, Ng IO.

Hepatology. 2014 Nov;60(5):1645-58. doi: 10.1002/hep.27320. Epub 2014 Oct 2.


The potential contributions of a Y-located protooncogene and its X homologue in sexual dimorphisms in hepatocellular carcinoma.

Kido T, Lo RC, Li Y, Lee J, Tabatabai ZL, Ng IO, Lau YF.

Hum Pathol. 2014 Sep;45(9):1847-58. doi: 10.1016/j.humpath.2014.05.002. Epub 2014 May 23.


Risk factors and indications for readmission after lower extremity amputation in the American College of Surgeons National Surgical Quality Improvement Program.

Curran T, Zhang JQ, Lo RC, Fokkema M, McCallum JC, Buck DB, Darling J, Schermerhorn ML.

J Vasc Surg. 2014 Nov;60(5):1315-1324. doi: 10.1016/j.jvs.2014.05.050. Epub 2014 Jun 28.


Pilot study of high-intensity focused ultrasound ablation as a bridging therapy for hepatocellular carcinoma patients wait-listed for liver transplantation.

Chok KS, Cheung TT, Lo RC, Chu FS, Tsang SH, Chan AC, Sharr WW, Fung JY, Dai WC, Chan SC, Fan ST, Lo CM.

Liver Transpl. 2014 Aug;20(8):912-21. doi: 10.1002/lt.23892. Epub 2014 Jun 24.


Relative importance of aneurysm diameter and body size for predicting abdominal aortic aneurysm rupture in men and women.

Lo RC, Lu B, Fokkema MT, Conrad M, Patel VI, Fillinger M, Matyal R, Schermerhorn ML; Vascular Study Group of New England,.

J Vasc Surg. 2014 May;59(5):1209-16. doi: 10.1016/j.jvs.2013.10.104. Epub 2013 Dec 30.


Clinical relevance of cranial nerve injury following carotid endarterectomy.

Fokkema M, de Borst GJ, Nolan BW, Indes J, Buck DB, Lo RC, Moll FL, Schermerhorn ML; Vascular Study Group of New England.

Eur J Vasc Endovasc Surg. 2014 Jan;47(1):2-7. doi: 10.1016/j.ejvs.2013.09.022. Epub 2013 Oct 1.


Presentation, treatment, and outcome differences between men and women undergoing revascularization or amputation for lower extremity peripheral arterial disease.

Lo RC, Bensley RP, Dahlberg SE, Matyal R, Hamdan AD, Wyers M, Chaikof EL, Schermerhorn ML.

J Vasc Surg. 2014 Feb;59(2):409-418.e3. doi: 10.1016/j.jvs.2013.07.114. Epub 2013 Sep 29.


Carotid stenting versus endarterectomy in patients undergoing reintervention after prior carotid endarterectomy.

Fokkema M, de Borst GJ, Nolan BW, Lo RC, Cambria RA, Powell RJ, Moll FL, Schermerhorn ML; Vascular Study Group of New England.

J Vasc Surg. 2014 Jan;59(1):8-15.e1-2. doi: 10.1016/j.jvs.2013.06.070. Epub 2013 Aug 22.


Epithelioid angiomyolipoma of the liver: a clinicopathologic study of 5 cases.

Lo RC.

Ann Diagn Pathol. 2013 Oct;17(5):412-5. doi: 10.1016/j.anndiagpath.2013.04.009. Epub 2013 Jun 17.


Simultaneous radicular cyst and mucoepidermoid carcinoma in the maxilla: a diagnostic nightmare.

Nabil S, Lo RC, Choi WS.

BMJ Case Rep. 2013 Jun 12;2013. pii: bcr2013010290. doi: 10.1136/bcr-2013-010290.


High-intensity focused ultrasound ablation: an effective bridging therapy for hepatocellular carcinoma patients.

Cheung TT, Fan ST, Chan SC, Chok KS, Chu FS, Jenkins CR, Lo RC, Fung JY, Chan AC, Sharr WW, Tsang SH, Dai WC, Poon RT, Lo CM.

World J Gastroenterol. 2013 May 28;19(20):3083-9. doi: 10.3748/wjg.v19.i20.3083.


Characterization of interleukin-1β in Helicobacter pylori-induced gastric inflammation and DNA methylation in interleukin-1 receptor type 1 knockout (IL-1R1(-/-)) mice.

Huang FY, Chan AO, Lo RC, Rashid A, Wong DK, Cho CH, Lai CL, Yuen MF.

Eur J Cancer. 2013 Aug;49(12):2760-70. doi: 10.1016/j.ejca.2013.03.031. Epub 2013 May 9.


Open repair of intact thoracoabdominal aortic aneurysms in the American College of Surgeons National Surgical Quality Improvement Program.

Bensley RP, Curran T, Hurks R, Lo RC, Wyers MC, Hamdan AD, Chaikof EL, Schermerhorn ML.

J Vasc Surg. 2013 Oct;58(4):894-900. doi: 10.1016/j.jvs.2013.03.037. Epub 2013 May 1.


Accuracy of administrative data versus clinical data to evaluate carotid endarterectomy and carotid stenting.

Bensley RP, Yoshida S, Lo RC, Fokkema M, Hamdan AD, Wyers MC, Chaikof EL, Schermerhorn ML.

J Vasc Surg. 2013 Aug;58(2):412-9. doi: 10.1016/j.jvs.2013.01.010. Epub 2013 Mar 13.


Post-transplant lymphoproliferative disorders in liver transplant recipients: a clinicopathological study.

Lo RC, Chan SC, Chan KL, Chiang AK, Lo CM, Ng IO.

J Clin Pathol. 2013 May;66(5):392-8. doi: 10.1136/jclinpath-2012-201139. Epub 2013 Feb 19.


In-hospital versus postdischarge adverse events following carotid endarterectomy.

Fokkema M, Bensley RP, Lo RC, Hamden AD, Wyers MC, Moll FL, de Borst GJ, Schermerhorn ML.

J Vasc Surg. 2013 Jun;57(6):1568-75, 1575.e1-3. doi: 10.1016/j.jvs.2012.11.072. Epub 2013 Feb 4.

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