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Items: 1 to 50 of 67

1.

Characterisation of infectious Ebola virus from the ongoing outbreak to guide response activities in the Democratic Republic of the Congo: a phylogenetic and in vitro analysis.

McMullan LK, Flint M, Chakrabarti A, Guerrero L, Lo MK, Porter D, Nichol ST, Spiropoulou CF, Albariño C.

Lancet Infect Dis. 2019 Sep;19(9):1023-1032. doi: 10.1016/S1473-3099(19)30291-9. Epub 2019 Jul 9.

PMID:
31300330
2.

Remdesivir (GS-5734) protects African green monkeys from Nipah virus challenge.

Lo MK, Feldmann F, Gary JM, Jordan R, Bannister R, Cronin J, Patel NR, Klena JD, Nichol ST, Cihlar T, Zaki SR, Feldmann H, Spiropoulou CF, de Wit E.

Sci Transl Med. 2019 May 29;11(494). pii: eaau9242. doi: 10.1126/scitranslmed.aau9242.

PMID:
31142680
3.

A Conserved Basic Patch and Central Kink in the Nipah Virus Phosphoprotein Multimerization Domain Are Essential for Polymerase Function.

Bruhn JF, Hotard AL, Spiropoulou CF, Lo MK, Saphire EO.

Structure. 2019 Apr 2;27(4):660-668.e4. doi: 10.1016/j.str.2019.01.012. Epub 2019 Feb 21.

PMID:
30799076
4.

A genome-wide CRISPR screen identifies N-acetylglucosamine-1-phosphate transferase as a potential antiviral target for Ebola virus.

Flint M, Chatterjee P, Lin DL, McMullan LK, Shrivastava-Ranjan P, Bergeron É, Lo MK, Welch SR, Nichol ST, Tai AW, Spiropoulou CF.

Nat Commun. 2019 Jan 17;10(1):285. doi: 10.1038/s41467-018-08135-4.

5.

Susceptibility of paramyxoviruses and filoviruses to inhibition by 2'-monofluoro- and 2'-difluoro-4'-azidocytidine analogs.

Lo MK, Jordan PC, Stevens S, Tam Y, Deval J, Nichol ST, Spiropoulou CF.

Antiviral Res. 2018 May;153:101-113. doi: 10.1016/j.antiviral.2018.03.009. Epub 2018 Mar 27.

6.

Development of a reverse genetics system for Sosuga virus allows rapid screening of antiviral compounds.

Welch SR, Chakrabarti AK, Wiggleton Guerrero L, Jenks HM, Lo MK, Nichol ST, Spiropoulou CF, Albariño CG.

PLoS Negl Trop Dis. 2018 Mar 9;12(3):e0006326. doi: 10.1371/journal.pntd.0006326. eCollection 2018 Mar.

7.

Initiation, extension, and termination of RNA synthesis by a paramyxovirus polymerase.

Jordan PC, Liu C, Raynaud P, Lo MK, Spiropoulou CF, Symons JA, Beigelman L, Deval J.

PLoS Pathog. 2018 Feb 9;14(2):e1006889. doi: 10.1371/journal.ppat.1006889. eCollection 2018 Feb.

8.

Higher levels of objectively measured sedentary behavior is associated with worse cognitive ability: Two-year follow-up study in community-dwelling older adults.

Ku PW, Liu YT, Lo MK, Chen LJ, Stubbs B.

Exp Gerontol. 2017 Dec 1;99:110-114. doi: 10.1016/j.exger.2017.09.014. Epub 2017 Sep 28.

PMID:
28962854
9.

4'-Azidocytidine (R1479) inhibits henipaviruses and other paramyxoviruses with high potency.

Hotard AL, He B, Nichol ST, Spiropoulou CF, Lo MK.

Antiviral Res. 2017 Aug;144:147-152. doi: 10.1016/j.antiviral.2017.06.011. Epub 2017 Jun 17.

10.

Evaluation of a TaqMan Array Card for Detection of Central Nervous System Infections.

Onyango CO, Loparev V, Lidechi S, Bhullar V, Schmid DS, Radford K, Lo MK, Rota P, Johnson BW, Munoz J, Oneko M, Burton D, Black CM, Neatherlin J, Montgomery JM, Fields B.

J Clin Microbiol. 2017 Jul;55(7):2035-2044. doi: 10.1128/JCM.02469-16. Epub 2017 Apr 12.

11.

GS-5734 and its parent nucleoside analog inhibit Filo-, Pneumo-, and Paramyxoviruses.

Lo MK, Jordan R, Arvey A, Sudhamsu J, Shrivastava-Ranjan P, Hotard AL, Flint M, McMullan LK, Siegel D, Clarke MO, Mackman RL, Hui HC, Perron M, Ray AS, Cihlar T, Nichol ST, Spiropoulou CF.

Sci Rep. 2017 Mar 6;7:43395. doi: 10.1038/srep43395.

12.

Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-f][triazin-4-amino] Adenine C-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses.

Siegel D, Hui HC, Doerffler E, Clarke MO, Chun K, Zhang L, Neville S, Carra E, Lew W, Ross B, Wang Q, Wolfe L, Jordan R, Soloveva V, Knox J, Perry J, Perron M, Stray KM, Barauskas O, Feng JY, Xu Y, Lee G, Rheingold AL, Ray AS, Bannister R, Strickley R, Swaminathan S, Lee WA, Bavari S, Cihlar T, Lo MK, Warren TK, Mackman RL.

J Med Chem. 2017 Mar 9;60(5):1648-1661. doi: 10.1021/acs.jmedchem.6b01594. Epub 2017 Feb 14.

PMID:
28124907
13.

Antibodies Against Henipa-Like Viruses in Brazilian Bats.

de Araujo J, Lo MK, Tamin A, Ometto TL, Thomazelli LM, Nardi MS, Hurtado RF, Nava A, Spiropoulou CF, Rota PA, Durigon EL.

Vector Borne Zoonotic Dis. 2017 Apr;17(4):271-274. doi: 10.1089/vbz.2016.2051. Epub 2017 Jan 19.

PMID:
28103156
14.

In vitro antiviral activity of adenosine analog NITD008 against tick-borne flaviviruses.

Lo MK, Shi PY, Chen YL, Flint M, Spiropoulou CF.

Antiviral Res. 2016 Jun;130:46-9. doi: 10.1016/j.antiviral.2016.03.013. Epub 2016 Mar 23.

15.

Genome-wide siRNA Screening at Biosafety Level 4 Reveals a Crucial Role for Fibrillarin in Henipavirus Infection.

Deffrasnes C, Marsh GA, Foo CH, Rootes CL, Gould CM, Grusovin J, Monaghan P, Lo MK, Tompkins SM, Adams TE, Lowenthal JW, Simpson KJ, Stewart CR, Bean AG, Wang LF.

PLoS Pathog. 2016 Mar 24;12(3):e1005478. doi: 10.1371/journal.ppat.1005478. eCollection 2016 Mar.

16.

Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys.

Warren TK, Jordan R, Lo MK, Ray AS, Mackman RL, Soloveva V, Siegel D, Perron M, Bannister R, Hui HC, Larson N, Strickley R, Wells J, Stuthman KS, Van Tongeren SA, Garza NL, Donnelly G, Shurtleff AC, Retterer CJ, Gharaibeh D, Zamani R, Kenny T, Eaton BP, Grimes E, Welch LS, Gomba L, Wilhelmsen CL, Nichols DK, Nuss JE, Nagle ER, Kugelman JR, Palacios G, Doerffler E, Neville S, Carra E, Clarke MO, Zhang L, Lew W, Ross B, Wang Q, Chun K, Wolfe L, Babusis D, Park Y, Stray KM, Trancheva I, Feng JY, Barauskas O, Xu Y, Wong P, Braun MR, Flint M, McMullan LK, Chen SS, Fearns R, Swaminathan S, Mayers DL, Spiropoulou CF, Lee WA, Nichol ST, Cihlar T, Bavari S.

Nature. 2016 Mar 17;531(7594):381-5. doi: 10.1038/nature17180. Epub 2016 Mar 2. Erratum in: ACS Chem Biol. 2016 May 20;11(5):1463.

17.

Ebola Virus Diagnostics: The US Centers for Disease Control and Prevention Laboratory in Sierra Leone, August 2014 to March 2015.

Flint M, Goodman CH, Bearden S, Blau DM, Amman BR, Basile AJ, Belser JA, Bergeron É, Bowen MD, Brault AC, Campbell S, Chakrabarti AK, Dodd KA, Erickson BR, Freeman MM, Gibbons A, Guerrero LW, Klena JD, Lash RR, Lo MK, McMullan LK, Momoh G, Massally JL, Goba A, Paddock CD, Priestley RA, Pyle M, Rayfield M, Russell BJ, Salzer JS, Sanchez AJ, Schuh AJ, Sealy TK, Steinau M, Stoddard RA, Taboy C, Turnsek M, Wang D, Zemtsova GE, Zivcec M, Spiropoulou CF, Ströher U, Towner JS, Nichol ST, Bird BH.

J Infect Dis. 2015 Oct 1;212 Suppl 2:S350-8. doi: 10.1093/infdis/jiv361. Epub 2015 Jul 30.

PMID:
26232439
18.

Development of a reverse genetics system to generate a recombinant Ebola virus Makona expressing a green fluorescent protein.

Albariño CG, Wiggleton Guerrero L, Lo MK, Nichol ST, Towner JS.

Virology. 2015 Oct;484:259-64. doi: 10.1016/j.virol.2015.06.013. Epub 2015 Jun 27.

19.

Inhibitors of cellular kinases with broad-spectrum antiviral activity for hemorrhagic fever viruses.

Mohr EL, McMullan LK, Lo MK, Spengler JR, Bergeron É, Albariño CG, Shrivastava-Ranjan P, Chiang CF, Nichol ST, Spiropoulou CF, Flint M.

Antiviral Res. 2015 Aug;120:40-7. doi: 10.1016/j.antiviral.2015.05.003. Epub 2015 May 16.

20.

Transcriptome Profiling of the Virus-Induced Innate Immune Response in Pteropus vampyrus and Its Attenuation by Nipah Virus Interferon Antagonist Functions.

Glennon NB, Jabado O, Lo MK, Shaw ML.

J Virol. 2015 Aug;89(15):7550-66. doi: 10.1128/JVI.00302-15. Epub 2015 May 13.

21.

A response to: Macroscopically detected female genital injury after consensual and non-consensual vaginal penetration: a prospective comparison study [20 (2013) 884-901].

Lo MK, Foley C, Healy C, Oliphant J, Kent S.

J Forensic Leg Med. 2014 Nov;28:47-9. doi: 10.1016/j.jflm.2014.08.011. Epub 2014 Aug 20. No abstract available.

PMID:
25440148
22.

Injectable scaffolds for bone regeneration.

Yasmeen S, Lo MK, Bajracharya S, Roldo M.

Langmuir. 2014 Nov 4;30(43):12977-85. doi: 10.1021/la503057w. Epub 2014 Oct 21.

PMID:
25296391
23.

Small interfering RNA inhibition of Andes virus replication.

Chiang CF, Albariňo CG, Lo MK, Spiropoulou CF.

PLoS One. 2014 Jun 12;9(6):e99764. doi: 10.1371/journal.pone.0099764. eCollection 2014.

24.

Evaluation of luciferase and GFP-expressing Nipah viruses for rapid quantitative antiviral screening.

Lo MK, Nichol ST, Spiropoulou CF.

Antiviral Res. 2014 Jun;106:53-60. doi: 10.1016/j.antiviral.2014.03.011. Epub 2014 Mar 27.

25.

Evolution and structural organization of the C proteins of paramyxovirinae.

Lo MK, Søgaard TM, Karlin DG.

PLoS One. 2014 Feb 25;9(2):e90003. doi: 10.1371/journal.pone.0090003. eCollection 2014.

26.

Single-dose replication-defective VSV-based Nipah virus vaccines provide protection from lethal challenge in Syrian hamsters.

Lo MK, Bird BH, Chattopadhyay A, Drew CP, Martin BE, Coleman JD, Rose JK, Nichol ST, Spiropoulou CF.

Antiviral Res. 2014 Jan;101:26-9. doi: 10.1016/j.antiviral.2013.10.012. Epub 2013 Oct 30.

27.

Activation and cell death in human dendritic cells infected with Nipah virus.

Gupta M, Lo MK, Spiropoulou CF.

Virology. 2013 Jun 20;441(1):49-56. doi: 10.1016/j.virol.2013.03.004. Epub 2013 Apr 13.

28.

Nipah virus infection outbreak with nosocomial and corpse-to-human transmission, Bangladesh.

Sazzad HM, Hossain MJ, Gurley ES, Ameen KM, Parveen S, Islam MS, Faruque LI, Podder G, Banu SS, Lo MK, Rollin PE, Rota PA, Daszak P, Rahman M, Luby SP.

Emerg Infect Dis. 2013 Feb;19(2):210-7. doi: 10.3201/eid1902.120971.

29.

Distinct and overlapping roles of Nipah virus P gene products in modulating the human endothelial cell antiviral response.

Lo MK, Peeples ME, Bellini WJ, Nichol ST, Rota PA, Spiropoulou CF.

PLoS One. 2012;7(10):e47790. doi: 10.1371/journal.pone.0047790. Epub 2012 Oct 19.

30.

Synthesis and micropatterning of photocatalytically reactive self-assembled monolayers covalently linked to Si(100) surfaces via a Si-C bond.

Lo MK, Gard MN, Goldsmith BR, Garcia-Garibay MA, Monbouquette HG.

Langmuir. 2012 Nov 20;28(46):16156-66. doi: 10.1021/la302880v. Epub 2012 Nov 9.

PMID:
23083520
31.

Molecular virology of the henipaviruses.

Rota PA, Lo MK.

Curr Top Microbiol Immunol. 2012;359:41-58. doi: 10.1007/82_2012_211. Review.

PMID:
22552699
32.

Characterization of Nipah virus from outbreaks in Bangladesh, 2008-2010.

Lo MK, Lowe L, Hummel KB, Sazzad HM, Gurley ES, Hossain MJ, Luby SP, Miller DM, Comer JA, Rollin PE, Bellini WJ, Rota PA.

Emerg Infect Dis. 2012 Feb;18(2):248-55. doi: 10.3201/eid1802.111492.

33.

Date palm sap linked to Nipah virus outbreak in Bangladesh, 2008.

Rahman MA, Hossain MJ, Sultana S, Homaira N, Khan SU, Rahman M, Gurley ES, Rollin PE, Lo MK, Comer JA, Lowe L, Rota PA, Ksiazek TG, Kenah E, Sharker Y, Luby SP.

Vector Borne Zoonotic Dis. 2012 Jan;12(1):65-72. doi: 10.1089/vbz.2011.0656. Epub 2011 Sep 16.

PMID:
21923274
34.

Capping-ligand effect on the stability of CdSe quantum dot Langmuir monolayers.

Radhakrishnan C, Lo MK, Knobler CM, Garcia-Garibay MA, Monbouquette HG.

Langmuir. 2011 Mar 15;27(6):2099-103. doi: 10.1021/la104244x. Epub 2011 Feb 17.

PMID:
21329375
35.

A response to: Chlamydia trachomatis infection in children: do not forget perinatal acquisition [17 (2010) 96-98].

Lo MK, Say PJ, Healy C.

J Forensic Leg Med. 2010 Nov;17(8):450-1. doi: 10.1016/j.jflm.2010.09.011. Epub 2010 Oct 28. No abstract available.

PMID:
21056885
36.

Off Label Antiviral Therapeutics for Henipaviruses: New Light Through Old Windows.

Aljofan M, Lo MK, Rota PA, Michalski WP, Mungall BA.

J Antivir Antiretrovir. 2010 Jan 1;2(1):1-10.

37.

Characterization of the antiviral and inflammatory responses against Nipah virus in endothelial cells and neurons.

Lo MK, Miller D, Aljofan M, Mungall BA, Rollin PE, Bellini WJ, Rota PA.

Virology. 2010 Aug 15;404(1):78-88.

38.

Use of monoclonal antibodies against Hendra and Nipah viruses in an antigen capture ELISA.

Chiang CF, Lo MK, Rota PA, Spiropoulou CF, Rollin PE.

Virol J. 2010 Jun 3;7:115. doi: 10.1186/1743-422X-7-115.

39.

Development and validation of equations estimating glomerular filtration rates in Chinese patients with type 2 diabetes.

Leung TK, Luk AO, So WY, Lo MK, Chan JC.

Kidney Int. 2010 Apr;77(8):729-35. doi: 10.1038/ki.2009.549. Epub 2010 Feb 17.

40.

Polymorphisms of cytotoxic T lymphocyte-associated antigen-4 and cytokine genes in Taiwanese patients with ankylosing spondylitis.

Lee WY, Chang YH, Lo MK, Chang CP, Yang SC, Yang TP, Ho KT, Juan CW, Shiau MY.

Tissue Antigens. 2010 Feb;75(2):119-26. doi: 10.1111/j.1399-0039.2009.01411.x. Epub 2009 Dec 18.

PMID:
20030788
41.

Antiviral activity of gliotoxin, gentian violet and brilliant green against Nipah and Hendra virus in vitro.

Aljofan M, Sganga ML, Lo MK, Rootes CL, Porotto M, Meyer AG, Saubern S, Moscona A, Mungall BA.

Virol J. 2009 Nov 4;6:187. doi: 10.1186/1743-422X-6-187.

42.

Development of a neutralization assay for Nipah virus using pseudotype particles.

Tamin A, Harcourt BH, Lo MK, Roth JA, Wolf MC, Lee B, Weingartl H, Audonnet JC, Bellini WJ, Rota PA.

J Virol Methods. 2009 Sep;160(1-2):1-6. doi: 10.1016/j.jviromet.2009.02.025. Epub 2009 Mar 9.

43.

Prevalence of use and the risk of adverse effects associated with complementary and alternative medicine in a cohort of patients receiving warfarin.

Leung VW, Shalansky SJ, Lo MK, Jadusingh EA.

Ann Pharmacother. 2009 May;43(5):875-81. doi: 10.1345/aph.1L631. Epub 2009 Apr 28.

PMID:
19401475
44.

Determination of the henipavirus phosphoprotein gene mRNA editing frequencies and detection of the C, V and W proteins of Nipah virus in virus-infected cells.

Lo MK, Harcourt BH, Mungall BA, Tamin A, Peeples ME, Bellini WJ, Rota PA.

J Gen Virol. 2009 Feb;90(Pt 2):398-404. doi: 10.1099/vir.0.007294-0.

PMID:
19141449
45.

The emergence of Nipah virus, a highly pathogenic paramyxovirus.

Lo MK, Rota PA.

J Clin Virol. 2008 Dec;43(4):396-400. doi: 10.1016/j.jcv.2008.08.007. Epub 2008 Oct 2. Review.

PMID:
18835214
46.

Nanoparticle-assisted high photoconductive gain in composites of polymer and fullerene.

Chen HY, Lo MK, Yang G, Monbouquette HG, Yang Y.

Nat Nanotechnol. 2008 Sep;3(9):543-7. doi: 10.1038/nnano.2008.206. Epub 2008 Jul 27.

47.

The C, V and W proteins of Nipah virus inhibit minigenome replication.

Sleeman K, Bankamp B, Hummel KB, Lo MK, Bellini WJ, Rota PA.

J Gen Virol. 2008 May;89(Pt 5):1300-8. doi: 10.1099/vir.0.83582-0.

PMID:
18420809
48.

Henipavirus V protein association with Polo-like kinase reveals functional overlap with STAT1 binding and interferon evasion.

Ludlow LE, Lo MK, Rodriguez JJ, Rota PA, Horvath CM.

J Virol. 2008 Jul;82(13):6259-71. doi: 10.1128/JVI.00409-08. Epub 2008 Apr 16.

49.

A novel study of association between Neisseria gonorrhoeae and the human carbohydrate blood groups.

Perry HE, Franklin RA, Bray SJ, Lo MK, Svensson LA, Henry SM.

Immunohematology. 2007;23(3):100-4.

PMID:
18284299
50.

Association of tumour necrosis factor alpha promoter polymorphisms with ankylosing spondylitis in Taiwan.

Shiau MY, Lo MK, Chang CP, Yang TP, Ho KT, Chang YH.

Ann Rheum Dis. 2007 Apr;66(4):562-3. No abstract available.

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