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Items: 1 to 50 of 351

1.

Reactivation of Epstein-Barr virus by a dual-responsive fluorescent EBNA1-targeting agent with Zn2+-chelating function.

Jiang L, Lung HL, Huang T, Lan R, Zha S, Chan LS, Thor W, Tsoi TH, Chau HF, Boreström C, Cobb SL, Tsao SW, Bian ZX, Law GL, Wong WT, Tai WC, Chau WY, Du Y, Tang LHX, Chiang AKS, Middeldorp JM, Lo KW, Mak NK, Long NJ, Wong KL.

Proc Natl Acad Sci U S A. 2019 Dec 10. pii: 201915372. doi: 10.1073/pnas.1915372116. [Epub ahead of print]

2.

Autophagy-Dependent Reactivation of Epstein-Barr Virus Lytic Cycle and Combinatorial Effects of Autophagy-Dependent and Independent Lytic Inducers in Nasopharyngeal Carcinoma.

Yiu SPT, Hui KF, Münz C, Lo KW, Tsao SW, Kao RYT, Yang D, Chiang AKS.

Cancers (Basel). 2019 Nov 26;11(12). pii: E1871. doi: 10.3390/cancers11121871.

3.

Novel policing techniques decrease gun-violence and the cost to the healthcare system.

Frisby JC, Kim TWB, Schultz EM, Adeyemo A, Lo KW, Hazelton JP, Miller LS.

Prev Med Rep. 2019 Oct 25;16:100995. doi: 10.1016/j.pmedr.2019.100995. eCollection 2019 Dec.

4.

NARD: whole-genome reference panel of 1779 Northeast Asians improves imputation accuracy of rare and low-frequency variants.

Yoo SK, Kim CU, Kim HL, Kim S, Shin JY, Kim N, Yang JSW, Lo KW, Cho B, Matsuda F, Schuster SC, Kim C, Kim JI, Seo JS.

Genome Med. 2019 Oct 22;11(1):64. doi: 10.1186/s13073-019-0677-z.

5.

Translational genomics of nasopharyngeal cancer.

Tsang CM, Lui VWY, Bruce JP, Pugh TJ, Lo KW.

Semin Cancer Biol. 2019 Sep 12. pii: S1044-579X(19)30284-6. doi: 10.1016/j.semcancer.2019.09.006. [Epub ahead of print] Review.

6.

Crucifera sulforaphane (SFN) inhibits the growth of nasopharyngeal carcinoma through DNA methyltransferase 1 (DNMT1)/Wnt inhibitory factor 1 (WIF1) axis.

Chen L, Chan LS, Lung HL, Yip TTC, Ngan RKC, Wong JWC, Lo KW, Ng WT, Lee AWM, Tsao GSW, Lung ML, Mak NK.

Phytomedicine. 2019 Oct;63:153058. doi: 10.1016/j.phymed.2019.153058. Epub 2019 Jul 29.

PMID:
31394414
7.

The ATP-binding cassette transporter ABCF1 is a hepatic oncofetal protein that promotes chemoresistance, EMT and cancer stemness in hepatocellular carcinoma.

Fung SW, Cheung PF, Yip CW, Ng LW, Cheung TT, Chong CC, Lee C, Lai PB, Chan AW, Tsao GS, Wong CH, Chan SL, Lo KW, Cheung ST.

Cancer Lett. 2019 Aug 10;457:98-109. doi: 10.1016/j.canlet.2019.05.010. Epub 2019 May 14.

8.

A ballistic model-based method for ranging small arms fire using a single acoustic sensor node.

Lo KW.

J Acoust Soc Am. 2019 Apr;145(4):2409. doi: 10.1121/1.5098772.

PMID:
31046312
9.

Liquid biopsy of HPV DNA in cervical cancer.

Cheung TH, Yim SF, Yu MY, Worley MJ Jr, Fiascone SJ, Chiu RWK, Lo KWK, Siu NSS, Wong MCS, Yeung ACM, Wong RRY, Chen ZG, Elias KM, Chung TKH, Berkowitz RS, Wong YF, Chan PKS.

J Clin Virol. 2019 May;114:32-36. doi: 10.1016/j.jcv.2019.03.005. Epub 2019 Mar 12.

PMID:
30913520
10.

mTORC2-mediated PDHE1α nuclear translocation links EBV-LMP1 reprogrammed glucose metabolism to cancer metastasis in nasopharyngeal carcinoma.

Zhang J, Jia L, Liu T, Yip YL, Tang WC, Lin W, Deng W, Lo KW, You C, Lung ML, Lung HL, Cheung AL, Tsao SW, Tsang CM.

Oncogene. 2019 Jun;38(24):4669-4684. doi: 10.1038/s41388-019-0749-y. Epub 2019 Feb 11.

11.

Repositioning Tacrolimus: Evaluation of the Effect of Short-Term Tacrolimus Treatment on Osteoprogenitor Cells and Primary Cells for Bone Regenerative Engineering.

O'Neill E, Rajpura K, Carbone EJ, Awale G, Kan HM, Lo KW.

Assay Drug Dev Technol. 2019 Feb/Mar;17(2):77-88. doi: 10.1089/adt.2018.876. Epub 2019 Jan 9.

PMID:
30624955
12.

Treatment of advanced hepatocellular carcinoma: immunotherapy from checkpoint blockade to potential of cellular treatment.

Siu EH, Chan AW, Chong CC, Chan SL, Lo KW, Cheung ST.

Transl Gastroenterol Hepatol. 2018 Nov 7;3:89. doi: 10.21037/tgh.2018.10.16. eCollection 2018. Review.

13.

The Wnt modulator ICG‑001 mediates the inhibition of nasopharyngeal carcinoma cell migration in vitro via the miR‑150/CD44 axis.

Chan LS, Man OY, Kwok HH, Chen L, Chan KC, Lung HL, Ngan RK, Wong RN, Lo KW, Lee AW, Tsao GS, Kahn M, Lung ML, Mak NK.

Int J Oncol. 2019 Mar;54(3):1010-1020. doi: 10.3892/ijo.2018.4664. Epub 2018 Dec 12.

PMID:
30569106
14.

EBNA1-targeted inhibitors: Novel approaches for the treatment of Epstein-Barr virus-associated cancers.

Jiang L, Xie C, Lung HL, Lo KW, Law GL, Mak NK, Wong KL.

Theranostics. 2018 Oct 22;8(19):5307-5319. doi: 10.7150/thno.26823. eCollection 2018. Review.

15.

Establishment and characterization of new tumor xenografts and cancer cell lines from EBV-positive nasopharyngeal carcinoma.

Lin W, Yip YL, Jia L, Deng W, Zheng H, Dai W, Ko JMY, Lo KW, Chung GTY, Yip KY, Lee SD, Kwan JS, Zhang J, Liu T, Chan JY, Kwong DL, Lee VH, Nicholls JM, Busson P, Liu X, Chiang AKS, Hui KF, Kwok H, Cheung ST, Cheung YC, Chan CK, Li B, Cheung AL, Hau PM, Zhou Y, Tsang CM, Middeldorp J, Chen H, Lung ML, Tsao SW.

Nat Commun. 2018 Nov 7;9(1):4663. doi: 10.1038/s41467-018-06889-5.

16.

FGF18, a prominent player in FGF signaling, promotes gastric tumorigenesis through autocrine manner and is negatively regulated by miR-590-5p.

Zhang J, Zhou Y, Huang T, Wu F, Pan Y, Dong Y, Wang Y, Chan AKY, Liu L, Kwan JSH, Cheung AHK, Wong CC, Lo AKF, Cheng ASL, Yu J, Lo KW, Kang W, To KF.

Oncogene. 2019 Jan;38(1):33-46. doi: 10.1038/s41388-018-0430-x. Epub 2018 Aug 6.

17.

RASAL2 promotes tumor progression through LATS2/YAP1 axis of hippo signaling pathway in colorectal cancer.

Pan Y, Tong JHM, Lung RWM, Kang W, Kwan JSH, Chak WP, Tin KY, Chung LY, Wu F, Ng SSM, Mak TWC, Yu J, Lo KW, Chan AWH, To KF.

Mol Cancer. 2018 Jul 23;17(1):102. doi: 10.1186/s12943-018-0853-6.

18.
19.

Genomic Landscapes of EBV-Associated Nasopharyngeal Carcinoma vs. HPV-Associated Head and Neck Cancer.

Ngan HL, Wang L, Lo KW, Lui VWY.

Cancers (Basel). 2018 Jun 21;10(7). pii: E210. doi: 10.3390/cancers10070210. Review.

20.

Injectable nanocomposite analgesic delivery system for musculoskeletal pain management.

Khanal M, Gohil SV, Kuyinu E, Kan HM, Knight BE, Baumbauer KM, Lo KW, Walker J, Laurencin CT, Nair LS.

Acta Biomater. 2018 Jul 1;74:280-290. doi: 10.1016/j.actbio.2018.05.038. Epub 2018 May 25.

21.

Preclinical evaluation of ribociclib and its synergistic effect in combination with alpelisib in non-keratinizing nasopharyngeal carcinoma.

Wong CH, Ma BBY, Hui CWC, Lo KW, Hui EP, Chan ATC.

Sci Rep. 2018 May 22;8(1):8010. doi: 10.1038/s41598-018-26201-1.

22.

Establishment of a nasopharyngeal carcinoma cell line capable of undergoing lytic Epstein-Barr virus reactivation.

Yip YL, Lin W, Deng W, Jia L, Lo KW, Busson P, Vérillaud B, Liu X, Tsang CM, Lung ML, Tsao SW.

Lab Invest. 2018 Aug;98(8):1093-1104. doi: 10.1038/s41374-018-0034-7. Epub 2018 May 16.

23.

Antitumor Activity of Nivolumab in Recurrent and Metastatic Nasopharyngeal Carcinoma: An International, Multicenter Study of the Mayo Clinic Phase 2 Consortium (NCI-9742).

Ma BBY, Lim WT, Goh BC, Hui EP, Lo KW, Pettinger A, Foster NR, Riess JW, Agulnik M, Chang AYC, Chopra A, Kish JA, Chung CH, Adkins DR, Cullen KJ, Gitlitz BJ, Lim DW, To KF, Chan KCA, Lo YMD, King AD, Erlichman C, Yin J, Costello BA, Chan ATC.

J Clin Oncol. 2018 May 10;36(14):1412-1418. doi: 10.1200/JCO.2017.77.0388. Epub 2018 Mar 27. Erratum in: J Clin Oncol. 2018 Aug 1;36(22):2360.

24.

Development of Targeted Nanoscale Drug Delivery System for Osteoarthritic Cartilage Tissue.

Jiang T, Kan HM, Rajpura K, Carbone EJ, Li Y, Lo KW.

J Nanosci Nanotechnol. 2018 Apr 1;18(4):2310-2317. doi: 10.1166/jnn.2018.14311.

PMID:
29442897
25.

The roles of ions on bone regeneration.

O'Neill E, Awale G, Daneshmandi L, Umerah O, Lo KW.

Drug Discov Today. 2018 Apr;23(4):879-890. doi: 10.1016/j.drudis.2018.01.049. Epub 2018 Feb 3. Review.

PMID:
29407177
26.

Biodegradable Piezoelectric Force Sensor.

Curry EJ, Ke K, Chorsi MT, Wrobel KS, Miller AN 3rd, Patel A, Kim I, Feng J, Yue L, Wu Q, Kuo CL, Lo KW, Laurencin CT, Ilies H, Purohit PK, Nguyen TD.

Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):909-914. doi: 10.1073/pnas.1710874115. Epub 2018 Jan 16.

27.

Ternary copper(II) complex: NCI60 screening, toxicity studies, and evaluation of efficacy in xenograft models of nasopharyngeal carcinoma.

Ahmad M, Suhaimi SN, Chu TL, Abdul Aziz N, Mohd Kornain NK, Samiulla DS, Lo KW, Ng CH, Khoo AS.

PLoS One. 2018 Jan 12;13(1):e0191295. doi: 10.1371/journal.pone.0191295. eCollection 2018.

28.

EBV-encoded miRNAs target ATM-mediated response in nasopharyngeal carcinoma.

Lung RW, Hau PM, Yu KH, Yip KY, Tong JH, Chak WP, Chan AW, Lam KH, Lo AK, Tin EK, Chau SL, Pang JC, Kwan JS, Busson P, Young LS, Yap LF, Tsao SW, To KF, Lo KW.

J Pathol. 2018 Apr;244(4):394-407. doi: 10.1002/path.5018. Epub 2018 Feb 16.

29.

OMSV enables accurate and comprehensive identification of large structural variations from nanochannel-based single-molecule optical maps.

Li L, Leung AK, Kwok TP, Lai YYY, Pang IK, Chung GT, Mak ACY, Poon A, Chu C, Li M, Wu JJK, Lam ET, Cao H, Lin C, Sibert J, Yiu SM, Xiao M, Lo KW, Kwok PY, Chan TF, Yip KY.

Genome Biol. 2017 Dec 1;18(1):230. doi: 10.1186/s13059-017-1356-2.

30.

Genomic profiles of nasopharyngeal carcinoma: The importance of histological subtyping and Epstein-Barr virus in situ assays.

Lui VWY, To KF, Lo KW.

Cancer. 2018 Jan 15;124(2):434-435. doi: 10.1002/cncr.31131. Epub 2017 Nov 22. No abstract available.

31.

Rapid visual and spectrophotometric nitrite detection by cyclometalated ruthenium complex.

Lo HS, Lo KW, Yeung CF, Wong CY.

Anal Chim Acta. 2017 Oct 16;990:135-140. doi: 10.1016/j.aca.2017.07.018. Epub 2017 Jul 14.

PMID:
29029736
32.

CD24, CD44 and EpCAM enrich for tumour-initiating cells in a newly established patient-derived xenograft of nasopharyngeal carcinoma.

Hoe SLL, Tan LP, Abdul Aziz N, Liew K, Teow SY, Abdul Razak FR, Chin YM, Mohamed Shahrehan NA, Chu TL, Mohd Kornain NK, Peh SC, Koay CE, Lo KW, Ahmad M, Ng CC, Khoo AS.

Sci Rep. 2017 Sep 28;7(1):12372. doi: 10.1038/s41598-017-12045-8.

33.

Epstein-Barr virus infection and nasopharyngeal carcinoma.

Tsao SW, Tsang CM, Lo KW.

Philos Trans R Soc Lond B Biol Sci. 2017 Oct 19;372(1732). pii: 20160270. doi: 10.1098/rstb.2016.0270. Review.

34.
35.

Liquid biopsy of PIK3CA mutations in cervical cancer in Hong Kong Chinese women.

Chung TKH, Cheung TH, Yim SF, Yu MY, Chiu RWK, Lo KWK, Lee IPC, Wong RRY, Lau KKM, Wang VW, Worley MJ Jr, Elias KM, Fiascone SJ, Smith DI, Berkowitz RS, Wong YF.

Gynecol Oncol. 2017 Aug;146(2):334-339. doi: 10.1016/j.ygyno.2017.05.038. Epub 2017 Jun 3.

PMID:
28587748
36.

The role of metabolic reprogramming in γ-herpesvirus-associated oncogenesis.

Lo AK, Dawson CW, Young LS, Lo KW.

Int J Cancer. 2017 Oct 15;141(8):1512-1521. doi: 10.1002/ijc.30795. Epub 2017 Jun 7. Review.

37.
38.

Harnessing cAMP signaling in musculoskeletal regenerative engineering.

Ifegwu OC, Awale G, Rajpura K, Lo KW, Laurencin CT.

Drug Discov Today. 2017 Jul;22(7):1027-1044. doi: 10.1016/j.drudis.2017.03.008. Epub 2017 Mar 27. Review.

PMID:
28359841
39.

Oncogenic S1P signalling in EBV-associated nasopharyngeal carcinoma activates AKT and promotes cell migration through S1P receptor 3.

Lee HM, Lo KW, Wei W, Tsao SW, Chung GTY, Ibrahim MH, Dawson CW, Murray PG, Paterson IC, Yap LF.

J Pathol. 2017 May;242(1):62-72. doi: 10.1002/path.4879. Epub 2017 Mar 15.

40.

Exome and genome sequencing of nasopharynx cancer identifies NF-κB pathway activating mutations.

Li YY, Chung GT, Lui VW, To KF, Ma BB, Chow C, Woo JK, Yip KY, Seo J, Hui EP, Mak MK, Rusan M, Chau NG, Or YY, Law MH, Law PP, Liu ZW, Ngan HL, Hau PM, Verhoeft KR, Poon PH, Yoo SK, Shin JY, Lee SD, Lun SW, Jia L, Chan AW, Chan JY, Lai PB, Fung CY, Hung ST, Wang L, Chang AM, Chiosea SI, Hedberg ML, Tsao SW, van Hasselt AC, Chan AT, Grandis JR, Hammerman PS, Lo KW.

Nat Commun. 2017 Jan 18;8:14121. doi: 10.1038/ncomms14121.

41.

Epstein-Barr Virus-Encoded Latent Membrane Protein 1 Upregulates Glucose Transporter 1 Transcription via the mTORC1/NF-κB Signaling Pathways.

Zhang J, Jia L, Lin W, Yip YL, Lo KW, Lau VMY, Zhu D, Tsang CM, Zhou Y, Deng W, Lung HL, Lung ML, Cheung LM, Tsao SW.

J Virol. 2017 Feb 28;91(6). pii: e02168-16. doi: 10.1128/JVI.02168-16. Print 2017 Mar 15.

42.

Downregulation of long non-coding RNA MEG3 in nasopharyngeal carcinoma.

Chak WP, Lung RW, Tong JH, Chan SY, Lun SW, Tsao SW, Lo KW, To KF.

Mol Carcinog. 2017 Mar;56(3):1041-1054. doi: 10.1002/mc.22569. Epub 2016 Oct 20.

PMID:
27597634
43.

IKKα-mediated biogenesis of miR-196a through interaction with Drosha regulates the sensitivity of cancer cells to radiotherapy.

Fang X, Jeong JH, Long X, Park SJ, Wang D, Shuai M, Wei R, Li C, Li S, Zhang S, Duran MB, Lo KW, Tsao SW, Glaser R, Luo Z, Feng X, Tian Y, Luo JL.

Cell Death Differ. 2017 Jun;24(6):1133. doi: 10.1038/cdd.2016.106. Epub 2016 Sep 16.

44.

Osteotropic nanoscale drug delivery systems based on small molecule bone-targeting moieties.

Carbone EJ, Rajpura K, Allen BN, Cheng E, Ulery BD, Lo KW.

Nanomedicine. 2017 Jan;13(1):37-47. doi: 10.1016/j.nano.2016.08.015. Epub 2016 Aug 22. Review.

PMID:
27562211
45.

MicroRNA-183 suppresses cancer stem-like cell properties in EBV-associated nasopharyngeal carcinoma.

Cheung CC, Lun SW, Chung GT, Chow C, Lo C, Choy KW, Lo KW.

BMC Cancer. 2016 Jul 19;16:495. doi: 10.1186/s12885-016-2525-5.

46.

Comprehensive characterization of the patient-derived xenograft and the paralleled primary hepatocellular carcinoma cell line.

Cheung PF, Yip CW, Ng LW, Lo KW, Chow C, Chan KF, Cheung TT, Cheung ST.

Cancer Cell Int. 2016 Jun 8;16:41. doi: 10.1186/s12935-016-0322-5. eCollection 2016.

47.

Overexpression of PIN1 Enhances Cancer Growth and Aggressiveness with Cyclin D1 Induction in EBV-Associated Nasopharyngeal Carcinoma.

Xu M, Cheung CC, Chow C, Lun SW, Cheung ST, Lo KW.

PLoS One. 2016 Jun 3;11(6):e0156833. doi: 10.1371/journal.pone.0156833. eCollection 2016.

48.
49.

Improvement Initiatives of Resuscitation Service in a Regional Rehabilitation Hospital in Hong Kong.

Ho Pik Lai E, Yeung SH, Leung KC, Lo KW, Ko Yuen Ting P, Lau Moon Yu J.

World Hosp Health Serv. 2016;52(1):45-8.

PMID:
27180476
50.

IKKα-mediated biogenesis of miR-196a through interaction with Drosha regulates the sensitivity of cancer cells to radiotherapy.

Fang X, Jeong JH, Long X, Park SJ, Wang D, Shuai M, Wei R, Li C, Li S, Zhang S, Duran MB, Lo KW, Tsao SW, Glaser R, Luo Z, Feng X, Tian Y, Luo JL.

Cell Death Differ. 2016 Sep 1;23(9):1471-82. doi: 10.1038/cdd.2016.32. Epub 2016 Apr 8. Retraction in: Cell Death Differ. 2017 Jun;24(6):1133.

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