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Items: 1 to 50 of 52

1.

Defining the in vivo characteristics of acute myeloid leukemia cells behavior by intravital imaging.

Duarte D, Amarteifio S, Ang H, Kong IY, Ruivo N, Pruessner G, Hawkins ED, Lo Celso C.

Immunol Cell Biol. 2019 Feb;97(2):229-235. doi: 10.1111/imcb.12216. Epub 2018 Dec 13.

2.

Multiple membrane extrusion sites drive megakaryocyte migration into bone marrow blood vessels.

Brown E, Carlin LM, Nerlov C, Lo Celso C, Poole AW.

Life Sci Alliance. 2018 May 21;1(2). pii: e201800061. doi: 10.26508/lsa.201800061.

3.

Shigella-Induced Emergency Granulopoiesis Protects Zebrafish Larvae from Secondary Infection.

Willis AR, Torraca V, Gomes MC, Shelley J, Mazon-Moya M, Filloux A, Lo Celso C, Mostowy S.

MBio. 2018 Jun 26;9(3). pii: e00933-18. doi: 10.1128/mBio.00933-18.

4.

Imaging methods used to study mouse and human HSC niches: Current and emerging technologies.

Tjin G, Flores-Figueroa E, Duarte D, Straszkowski L, Scott M, Khorshed RA, Purton LE, Lo Celso C.

Bone. 2019 Feb;119:19-35. doi: 10.1016/j.bone.2018.04.022. Epub 2018 Apr 25. Review.

PMID:
29704697
5.

The interplay of leukemia cells and the bone marrow microenvironment.

Duarte D, Hawkins ED, Lo Celso C.

Blood. 2018 Apr 5;131(14):1507-1511. doi: 10.1182/blood-2017-12-784132. Epub 2018 Feb 27. Review.

6.

Redirection to the bone marrow improves T cell persistence and antitumor functions.

Khan AB, Carpenter B, Santos E Sousa P, Pospori C, Khorshed R, Griffin J, Velica P, Zech M, Ghorashian S, Forrest C, Thomas S, Gonzalez Anton S, Ahmadi M, Holler A, Flutter B, Ramirez-Ortiz Z, Means TK, Bennett CL, Stauss H, Morris E, Lo Celso C, Chakraverty R.

J Clin Invest. 2018 May 1;128(5):2010-2024. doi: 10.1172/JCI97454. Epub 2018 Apr 9.

7.

Proliferation dynamics of acute myeloid leukaemia and haematopoietic progenitors competing for bone marrow space.

Akinduro O, Weber TS, Ang H, Haltalli MLR, Ruivo N, Duarte D, Rashidi NM, Hawkins ED, Duffy KR, Lo Celso C.

Nat Commun. 2018 Feb 6;9(1):519. doi: 10.1038/s41467-017-02376-5.

8.

Inhibition of Endosteal Vascular Niche Remodeling Rescues Hematopoietic Stem Cell Loss in AML.

Duarte D, Hawkins ED, Akinduro O, Ang H, De Filippo K, Kong IY, Haltalli M, Ruivo N, Straszkowski L, Vervoort SJ, McLean C, Weber TS, Khorshed R, Pirillo C, Wei A, Ramasamy SK, Kusumbe AP, Duffy K, Adams RH, Purton LE, Carlin LM, Lo Celso C.

Cell Stem Cell. 2018 Jan 4;22(1):64-77.e6. doi: 10.1016/j.stem.2017.11.006. Epub 2017 Dec 21.

9.

Single Cell Phenotyping Reveals Heterogeneity Among Hematopoietic Stem Cells Following Infection.

MacLean AL, Smith MA, Liepe J, Sim A, Khorshed R, Rashidi NM, Scherf N, Krinner A, Roeder I, Lo Celso C, Stumpf MPH.

Stem Cells. 2017 Nov;35(11):2292-2304. doi: 10.1002/stem.2692. Epub 2017 Sep 24.

10.

The passive biomechanics of human pelvic collecting lymphatic vessels.

Athanasiou D, Edgar LT, Jafarnejad M, Nixon K, Duarte D, Hawkins ED, Jamalian S, Cunnea P, Lo Celso C, Kobayashi S, Fotopoulou C, Moore JE Jr.

PLoS One. 2017 Aug 21;12(8):e0183222. doi: 10.1371/journal.pone.0183222. eCollection 2017.

11.

Intravital microscopy in historic and contemporary immunology.

Secklehner J, Lo Celso C, Carlin LM.

Immunol Cell Biol. 2017 Jul;95(6):506-513. doi: 10.1038/icb.2017.25. Epub 2017 Apr 3. Review.

12.

Revealing the inner workings of human HSC adhesion.

Lo Celso C.

Blood. 2017 Feb 23;129(8):921-922. doi: 10.1182/blood-2016-12-755520. No abstract available.

13.

The evolving view of the hematopoietic stem cell niche.

Beerman I, Luis TC, Singbrant S, Lo Celso C, Méndez-Ferrer S.

Exp Hematol. 2017 Jun;50:22-26. doi: 10.1016/j.exphem.2017.01.008. Epub 2017 Feb 9. Review.

14.

T-cell acute leukaemia exhibits dynamic interactions with bone marrow microenvironments.

Hawkins ED, Duarte D, Akinduro O, Khorshed RA, Passaro D, Nowicka M, Straszkowski L, Scott MK, Rothery S, Ruivo N, Foster K, Waibel M, Johnstone RW, Harrison SJ, Westerman DA, Quach H, Gribben J, Robinson MD, Purton LE, Bonnet D, Lo Celso C.

Nature. 2016 Oct 27;538(7626):518-522. doi: 10.1038/nature19801. Epub 2016 Oct 17.

15.

Concise Review: Stem Cell Population Biology: Insights from Hematopoiesis.

MacLean AL, Lo Celso C, Stumpf MP.

Stem Cells. 2017 Jan;35(1):80-88. doi: 10.1002/stem.2508. Epub 2016 Oct 26. Review.

16.

Proximity-Based Differential Single-Cell Analysis of the Niche to Identify Stem/Progenitor Cell Regulators.

Silberstein L, Goncalves KA, Kharchenko PV, Turcotte R, Kfoury Y, Mercier F, Baryawno N, Severe N, Bachand J, Spencer JA, Papazian A, Lee D, Chitteti BR, Srour EF, Hoggatt J, Tate T, Lo Celso C, Ono N, Nutt S, Heino J, Sipilä K, Shioda T, Osawa M, Lin CP, Hu GF, Scadden DT.

Cell Stem Cell. 2016 Oct 6;19(4):530-543. doi: 10.1016/j.stem.2016.07.004. Epub 2016 Aug 11.

17.

Automated Identification and Localization of Hematopoietic Stem Cells in 3D Intravital Microscopy Data.

Khorshed RA, Hawkins ED, Duarte D, Scott MK, Akinduro OA, Rashidi NM, Spitaler M, Lo Celso C.

Stem Cell Reports. 2015 Jul 14;5(1):139-53. doi: 10.1016/j.stemcr.2015.05.017. Epub 2015 Jun 25.

18.

Haematopoietic focal adhesion kinase deficiency alters haematopoietic homeostasis to drive tumour metastasis.

Batista S, Maniati E, Reynolds LE, Tavora B, Lees DM, Fernandez I, Elia G, Casanovas O, Lo Celso C, Hagemann T, Hodivala-Dilke K.

Nat Commun. 2014 Oct 1;5:5054. doi: 10.1038/ncomms6054.

PMID:
25270220
19.

In vivo 4-dimensional tracking of hematopoietic stem and progenitor cells in adult mouse calvarial bone marrow.

Scott MK, Akinduro O, Lo Celso C.

J Vis Exp. 2014 Sep 4;(91):e51683. doi: 10.3791/51683.

20.

Flying back to the nest: Intravital microscopy reveals how the niche can induce stemness.

Rashidi NM, Lo Celso C.

Intravital. 2014 Aug 11;3(2):e29653. doi: 10.4161/intv.29653. eCollection 2014. No abstract available.

21.

In vivo time-lapse imaging shows diverse niche engagement by quiescent and naturally activated hematopoietic stem cells.

Rashidi NM, Scott MK, Scherf N, Krinner A, Kalchschmidt JS, Gounaris K, Selkirk ME, Roeder I, Lo Celso C.

Blood. 2014 Jul 3;124(1):79-83. doi: 10.1182/blood-2013-10-534859. Epub 2014 May 21.

22.

Deciphering hematopoietic stem cells in their niches: a critical appraisal of genetic models, lineage tracing, and imaging strategies.

Joseph C, Quach JM, Walkley CR, Lane SW, Lo Celso C, Purton LE.

Cell Stem Cell. 2013 Nov 7;13(5):520-33. doi: 10.1016/j.stem.2013.10.010. Review.

23.

From seeing to believing: labelling strategies for in vivo cell-tracking experiments.

Progatzky F, Dallman MJ, Lo Celso C.

Interface Focus. 2013 Jun 6;3(3):20130001. doi: 10.1098/rsfs.2013.0001.

24.

Population dynamics of normal and leukaemia stem cells in the haematopoietic stem cell niche show distinct regimes where leukaemia will be controlled.

MacLean AL, Lo Celso C, Stumpf MP.

J R Soc Interface. 2013 Jan 24;10(81):20120968. doi: 10.1098/rsif.2012.0968. Print 2013 Apr 6.

25.

Subdivision of bone marrow microenvironments: purpose built homes for haematopoietic stem cells.

Hawkins ED, Lo Celso C.

EMBO J. 2013 Jan 23;32(2):176-7. doi: 10.1038/emboj.2012.337. Epub 2012 Dec 18. No abstract available.

26.

In vivo imaging of hematopoietic stem cells in the bone marrow niche.

Barrett O, Sottocornola R, Lo Celso C.

Methods Mol Biol. 2012;916:231-42. doi: 10.1007/978-1-61779-980-8_18.

PMID:
22914945
27.

Dormancy in the stem cell niche.

Sottocornola R, Lo Celso C.

Stem Cell Res Ther. 2012 Mar 19;3(2):10. doi: 10.1186/scrt101. Review.

28.

The haematopoietic stem cell niche at a glance.

Lo Celso C, Scadden DT.

J Cell Sci. 2011 Nov 1;124(Pt 21):3529-35. doi: 10.1242/jcs.074112. No abstract available.

29.

Differential niche and Wnt requirements during acute myeloid leukemia progression.

Lane SW, Wang YJ, Lo Celso C, Ragu C, Bullinger L, Sykes SM, Ferraro F, Shterental S, Lin CP, Gilliland DG, Scadden DT, Armstrong SA, Williams DA.

Blood. 2011 Sep 8;118(10):2849-56. doi: 10.1182/blood-2011-03-345165. Epub 2011 Jul 15.

30.

In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche.

Fujisaki J, Wu J, Carlson AL, Silberstein L, Putheti P, Larocca R, Gao W, Saito TI, Lo Celso C, Tsuyuzaki H, Sato T, Côté D, Sykes M, Strom TB, Scadden DT, Lin CP.

Nature. 2011 Jun 8;474(7350):216-9. doi: 10.1038/nature10160.

31.

Crosstalk between NOTCH and AKT signaling during murine megakaryocyte lineage specification.

Cornejo MG, Mabialah V, Sykes SM, Khandan T, Lo Celso C, Lopez CK, Rivera-Muñoz P, Rameau P, Tothova Z, Aster JC, DePinho RA, Scadden DT, Gilliland DG, Mercher T.

Blood. 2011 Aug 4;118(5):1264-73. doi: 10.1182/blood-2011-01-328567. Epub 2011 Jun 7.

32.

Guanine nucleotide exchange factor Vav1 regulates perivascular homing and bone marrow retention of hematopoietic stem and progenitor cells.

Sanchez-Aguilera A, Lee YJ, Lo Celso C, Ferraro F, Brumme K, Mondal S, Kim C, Dorrance A, Luo HR, Scadden DT, Williams DA.

Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9607-12. doi: 10.1073/pnas.1102018108. Epub 2011 May 23.

33.

The SKP2 E3 ligase regulates basal homeostasis and stress-induced regeneration of HSCs.

Rodriguez S, Wang L, Mumaw C, Srour EF, Lo Celso C, Nakayama K, Carlesso N.

Blood. 2011 Jun 16;117(24):6509-19. doi: 10.1182/blood-2010-11-321521. Epub 2011 Apr 18.

34.

In vivo imaging of transplanted hematopoietic stem and progenitor cells in mouse calvarium bone marrow.

Lo Celso C, Lin CP, Scadden DT.

Nat Protoc. 2011 Jan;6(1):1-14. doi: 10.1038/nprot.2010.168. Epub 2010 Dec 9.

35.

The Apc(min) mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS.

Lane SW, Sykes SM, Al-Shahrour F, Shterental S, Paktinat M, Lo Celso C, Jesneck JL, Ebert BL, Williams DA, Gilliland DG.

Blood. 2010 Apr 29;115(17):3489-97. doi: 10.1182/blood-2009-11-251728. Epub 2010 Mar 2. Erratum in: Blood. 2014 Jan 9;123(2):301.

36.

Every cloud has a silver lining.

Lo Celso C.

Blood. 2010 Jan 21;115(3):438-9. doi: 10.1182/blood-2009-10-247577. No abstract available.

37.

In vivo imaging of hematopoietic stem cells and their microenvironment.

Lo Celso C, Wu JW, Lin CP.

J Biophotonics. 2009 Nov;2(11):619-31. doi: 10.1002/jbio.200910072. Review.

PMID:
19847800
38.

Haematopoietic stem cells depend on Galpha(s)-mediated signalling to engraft bone marrow.

Adams GB, Alley IR, Chung UI, Chabner KT, Jeanson NT, Lo Celso C, Marsters ES, Chen M, Weinstein LS, Lin CP, Kronenberg HM, Scadden DT.

Nature. 2009 May 7;459(7243):103-7. doi: 10.1038/nature07859. Epub 2009 Mar 25.

39.

Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche.

Lo Celso C, Fleming HE, Wu JW, Zhao CX, Miake-Lye S, Fujisaki J, Côté D, Rowe DW, Lin CP, Scadden DT.

Nature. 2009 Jan 1;457(7225):92-6. doi: 10.1038/nature07434. Epub 2008 Dec 3.

40.

Isolation and transplantation of hematopoietic stem cells (HSCs).

Lo Celso C, Scadden D.

J Vis Exp. 2007 Feb 25;(2):157. doi: 10.3791/157. No abstract available.

41.

Analysis of the hematopoietic stem cell niche.

Lo Celso C, Klein RJ, Scadden DT.

Curr Protoc Stem Cell Biol. 2007 Nov;Chapter 2:Unit 2A.5. doi: 10.1002/9780470151808.sc02a05s3.

PMID:
18785177
42.

Normal ovarian surface epithelial label-retaining cells exhibit stem/progenitor cell characteristics.

Szotek PP, Chang HL, Brennand K, Fujino A, Pieretti-Vanmarcke R, Lo Celso C, Dombkowski D, Preffer F, Cohen KS, Teixeira J, Donahoe PK.

Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12469-73. doi: 10.1073/pnas.0805012105. Epub 2008 Aug 18. Erratum in: Proc Natl Acad Sci U S A. 2008 Dec 2;105(48):19024.

43.

Hematopoietic stem cell responsiveness to exogenous signals is limited by caspase-3.

Janzen V, Fleming HE, Riedt T, Karlsson G, Riese MJ, Lo Celso C, Reynolds G, Milne CD, Paige CJ, Karlsson S, Woo M, Scadden DT.

Cell Stem Cell. 2008 Jun 5;2(6):584-94. doi: 10.1016/j.stem.2008.03.012.

44.

Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo.

Fleming HE, Janzen V, Lo Celso C, Guo J, Leahy KM, Kronenberg HM, Scadden DT.

Cell Stem Cell. 2008 Mar 6;2(3):274-83. doi: 10.1016/j.stem.2008.01.003.

45.

Stem cells remember their grade.

Lo Celso C, Scadden DT.

Cell Stem Cell. 2007 Aug 16;1(2):132-4. doi: 10.1016/j.stem.2007.07.011.

46.

Characterization of bipotential epidermal progenitors derived from human sebaceous gland: contrasting roles of c-Myc and beta-catenin.

Lo Celso C, Berta MA, Braun KM, Frye M, Lyle S, Zouboulis CC, Watt FM.

Stem Cells. 2008 May;26(5):1241-52. doi: 10.1634/stemcells.2007-0651. Epub 2008 Feb 28.

47.

Jagged 1 is a beta-catenin target gene required for ectopic hair follicle formation in adult epidermis.

Estrach S, Ambler CA, Lo Celso C, Hozumi K, Watt FM.

Development. 2006 Nov;133(22):4427-38. Epub 2006 Oct 11.

48.

Epidermal stem cells: an update.

Watt FM, Lo Celso C, Silva-Vargas V.

Curr Opin Genet Dev. 2006 Oct;16(5):518-24. Epub 2006 Aug 17. Review.

PMID:
16919447
49.

HAN11 binds mDia1 and controls GLI1 transcriptional activity.

Morita K, Lo Celso C, Spencer-Dene B, Zouboulis CC, Watt FM.

J Dermatol Sci. 2006 Oct;44(1):11-20. Epub 2006 Aug 2.

PMID:
16887337
50.

Beta-catenin and Hedgehog signal strength can specify number and location of hair follicles in adult epidermis without recruitment of bulge stem cells.

Silva-Vargas V, Lo Celso C, Giangreco A, Ofstad T, Prowse DM, Braun KM, Watt FM.

Dev Cell. 2005 Jul;9(1):121-31.

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