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Items: 1 to 50 of 353

1.

Half-life extension and non-human primate pharmacokinetic safety studies of i-body AD-114 targeting human CXCR4.

Griffiths K, Binder U, McDowell W, Tommasi R, Frigerio M, Darby WG, Hosking CG, Renaud L, Machacek M, Lloyd P, Skerra A, Foley M.

MAbs. 2019 Oct;11(7):1331-1340. doi: 10.1080/19420862.2019.1626652. Epub 2019 Aug 23.

PMID:
31156041
2.

Genomic Drivers of Poor Prognosis and Enzalutamide Resistance in Metastatic Castration-resistant Prostate Cancer.

Chen WS, Aggarwal R, Zhang L, Zhao SG, Thomas GV, Beer TM, Quigley DA, Foye A, Playdle D, Huang J, Lloyd P, Lu E, Sun D, Guan X, Rettig M, Gleave M, Evans CP, Youngren J, True L, Lara P, Kothari V, Xia Z, Chi KN, Reiter RE, Maher CA, Feng FY, Small EJ, Alumkal JJ; West Coast Prostate Cancer Dream Team.

Eur Urol. 2019 Mar 27. pii: S0302-2838(19)30206-4. doi: 10.1016/j.eururo.2019.03.020. [Epub ahead of print]

PMID:
30928160
3.

Whole-Genome and Transcriptional Analysis of Treatment-Emergent Small-Cell Neuroendocrine Prostate Cancer Demonstrates Intraclass Heterogeneity.

Aggarwal RR, Quigley DA, Huang J, Zhang L, Beer TM, Rettig MB, Reiter RE, Gleave ME, Thomas GV, Foye A, Playdle D, Lloyd P, Chi KN, Evans CP, Lara PN, Feng FY, Alumkal JJ, Small EJ.

Mol Cancer Res. 2019 Jun;17(6):1235-1240. doi: 10.1158/1541-7786.MCR-18-1101. Epub 2019 Mar 27.

PMID:
30918106
4.

Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer.

Quigley DA, Dang HX, Zhao SG, Lloyd P, Aggarwal R, Alumkal JJ, Foye A, Kothari V, Perry MD, Bailey AM, Playdle D, Barnard TJ, Zhang L, Zhang J, Youngren JF, Cieslik MP, Parolia A, Beer TM, Thomas G, Chi KN, Gleave M, Lack NA, Zoubeidi A, Reiter RE, Rettig MB, Witte O, Ryan CJ, Fong L, Kim W, Friedlander T, Chou J, Li H, Das R, Li H, Moussavi-Baygi R, Goodarzi H, Gilbert LA, Lara PN Jr, Evans CP, Goldstein TC, Stuart JM, Tomlins SA, Spratt DE, Cheetham RK, Cheng DT, Farh K, Gehring JS, Hakenberg J, Liao A, Febbo PG, Shon J, Sickler B, Batzoglou S, Knudsen KE, He HH, Huang J, Wyatt AW, Dehm SM, Ashworth A, Chinnaiyan AM, Maher CA, Small EJ, Feng FY.

Cell. 2018 Oct 18;175(3):889. doi: 10.1016/j.cell.2018.10.019. No abstract available.

5.

DNA Repair Gene Alterations and PARP Inhibitor Response in Patients With Metastatic Castration-Resistant Prostate Cancer.

Lu E, Thomas GV, Chen Y, Wyatt AW, Lloyd P, Youngren J, Quigley D, Bergan R, Bailey S, Beer TM, Feng FY, Small EJ, Alumkal JJ.

J Natl Compr Canc Netw. 2018 Aug;16(8):933-937. doi: 10.6004/jnccn.2018.7020.

PMID:
30099369
6.

Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer.

Quigley DA, Dang HX, Zhao SG, Lloyd P, Aggarwal R, Alumkal JJ, Foye A, Kothari V, Perry MD, Bailey AM, Playdle D, Barnard TJ, Zhang L, Zhang J, Youngren JF, Cieslik MP, Parolia A, Beer TM, Thomas G, Chi KN, Gleave M, Lack NA, Zoubeidi A, Reiter RE, Rettig MB, Witte O, Ryan CJ, Fong L, Kim W, Friedlander T, Chou J, Li H, Das R, Li H, Moussavi-Baygi R, Goodarzi H, Gilbert LA, Lara PN Jr, Evans CP, Goldstein TC, Stuart JM, Tomlins SA, Spratt DE, Cheetham RK, Cheng DT, Farh K, Gehring JS, Hakenberg J, Liao A, Febbo PG, Shon J, Sickler B, Batzoglou S, Knudsen KE, He HH, Huang J, Wyatt AW, Dehm SM, Ashworth A, Chinnaiyan AM, Maher CA, Small EJ, Feng FY.

Cell. 2018 Jul 26;174(3):758-769.e9. doi: 10.1016/j.cell.2018.06.039. Epub 2018 Jul 19. Erratum in: Cell. 2018 Oct 18;175(3):889.

7.

Clinical and Genomic Characterization of Treatment-Emergent Small-Cell Neuroendocrine Prostate Cancer: A Multi-institutional Prospective Study.

Aggarwal R, Huang J, Alumkal JJ, Zhang L, Feng FY, Thomas GV, Weinstein AS, Friedl V, Zhang C, Witte ON, Lloyd P, Gleave M, Evans CP, Youngren J, Beer TM, Rettig M, Wong CK, True L, Foye A, Playdle D, Ryan CJ, Lara P, Chi KN, Uzunangelov V, Sokolov A, Newton Y, Beltran H, Demichelis F, Rubin MA, Stuart JM, Small EJ.

J Clin Oncol. 2018 Aug 20;36(24):2492-2503. doi: 10.1200/JCO.2017.77.6880. Epub 2018 Jul 9.

8.
9.

Hidden Gratings in Holographic Liquid Crystal Polymer-Dispersed Liquid Crystal Films.

De Sio L, Lloyd PF, Tabiryan NV, Bunning TJ.

ACS Appl Mater Interfaces. 2018 Apr 18;10(15):13107-13112. doi: 10.1021/acsami.8b02821. Epub 2018 Apr 4.

PMID:
29575892
10.

Linkage of 1999-2012 National Health Interview Survey and National Health and Nutrition Examination Survey Data to U.S. Department of Housing and Urban Development Administrative Records.

Lloyd PC, Helms VE, Simon AE, Golden C, Brittain J, Call E, Mirel LB, Steffen BL, Sperling J, Rudd EC, Parker JD, Star CS.

Vital Health Stat 1. 2017 Oct;(60):1-40.

11.

Electrical Control of Shape in Voxelated Liquid Crystalline Polymer Nanocomposites.

Guin T, Kowalski BA, Rao R, Auguste AD, Grabowski CA, Lloyd PF, Tondiglia VP, Maruyama B, Vaia RA, White TJ.

ACS Appl Mater Interfaces. 2018 Jan 10;10(1):1187-1194. doi: 10.1021/acsami.7b13814. Epub 2017 Dec 26.

PMID:
29239172
12.

Concordance of Circulating Tumor DNA and Matched Metastatic Tissue Biopsy in Prostate Cancer.

Wyatt AW, Annala M, Aggarwal R, Beja K, Feng F, Youngren J, Foye A, Lloyd P, Nykter M, Beer TM, Alumkal JJ, Thomas GV, Reiter RE, Rettig MB, Evans CP, Gao AC, Chi KN, Small EJ, Gleave ME.

J Natl Cancer Inst. 2017 Dec 1;109(12). doi: 10.1093/jnci/djx118.

13.

Axillary tumour burden in women with a fine-needle aspiration/core biopsy-proven positive node on ultrasonography compared to women with a positive sentinel node.

Lloyd P, Theophilidou E, Newcombe RG, Pugh L, Goyal A.

Br J Surg. 2017 Dec;104(13):1811-1815. doi: 10.1002/bjs.10661. Epub 2017 Oct 9.

PMID:
28991362
14.

Androgen Receptor Deregulation Drives Bromodomain-Mediated Chromatin Alterations in Prostate Cancer.

Urbanucci A, Barfeld SJ, Kytölä V, Itkonen HM, Coleman IM, Vodák D, Sjöblom L, Sheng X, Tolonen T, Minner S, Burdelski C, Kivinummi KK, Kohvakka A, Kregel S, Takhar M, Alshalalfa M, Davicioni E, Erho N, Lloyd P, Karnes RJ, Ross AE, Schaeffer EM, Vander Griend DJ, Knapp S, Corey E, Feng FY, Nelson PS, Saatcioglu F, Knudsen KE, Tammela TLJ, Sauter G, Schlomm T, Nykter M, Visakorpi T, Mills IG.

Cell Rep. 2017 Jun 6;19(10):2045-2059. doi: 10.1016/j.celrep.2017.05.049.

15.

HUD Housing Assistance Associated With Lower Uninsurance Rates And Unmet Medical Need.

Simon AE, Fenelon A, Helms V, Lloyd PC, Rossen LM.

Health Aff (Millwood). 2017 Jun 1;36(6):1016-1023. doi: 10.1377/hlthaff.2016.1152.

16.

Analysis of Circulating Cell-Free DNA Identifies Multiclonal Heterogeneity of BRCA2 Reversion Mutations Associated with Resistance to PARP Inhibitors.

Quigley D, Alumkal JJ, Wyatt AW, Kothari V, Foye A, Lloyd P, Aggarwal R, Kim W, Lu E, Schwartzman J, Beja K, Annala M, Das R, Diolaiti M, Pritchard C, Thomas G, Tomlins S, Knudsen K, Lord CJ, Ryan C, Youngren J, Beer TM, Ashworth A, Small EJ, Feng FY.

Cancer Discov. 2017 Sep;7(9):999-1005. doi: 10.1158/2159-8290.CD-17-0146. Epub 2017 Apr 27.

17.

Housing Assistance Programs and Adult Health in the United States.

Fenelon A, Mayne P, Simon AE, Rossen LM, Helms V, Lloyd P, Sperling J, Steffen BL.

Am J Public Health. 2017 Apr;107(4):571-578. doi: 10.2105/AJPH.2016.303649. Epub 2017 Feb 16.

18.

State of salaries.

Lloyd P.

Nurs Stand. 2016 Nov 2;31(10):30.

PMID:
27861022
19.

Housing Assistance and Blood Lead Levels: Children in the United States, 2005-2012.

Ahrens KA, Haley BA, Rossen LM, Lloyd PC, Aoki Y.

Am J Public Health. 2016 Nov;106(11):2049-2056. Epub 2016 Sep 15.

20.

Secukinumab, a fully human anti-interleukin-17A monoclonal antibody, exhibits minimal immunogenicity in patients with moderate-to-severe plaque psoriasis.

Reich K, Blauvelt A, Armstrong A, Langley RG, Fox T, Huang J, Papavassilis C, Liang E, Lloyd P, Bruin G.

Br J Dermatol. 2017 Mar;176(3):752-758. doi: 10.1111/bjd.14965. Epub 2016 Nov 22.

PMID:
27518376
21.

Development of a Pitch Discrimination Screening Test for Preschool Children.

Abramson MK, Lloyd PJ.

J Am Acad Audiol. 2016 Apr;27(4):281-92. doi: 10.3766/jaaa.14052.

PMID:
27115239
22.

Adult Mortality Probability and Nest Predation Rates Explain Parental Effort in Warming Eggs with Consequences for Embryonic Development Time.

Martin TE, Oteyza JC, Boyce AJ, Lloyd P, Ton R.

Am Nat. 2015 Aug;186(2):223-36. doi: 10.1086/681986. Epub 2015 May 12.

PMID:
26655151
23.

Self-management of chronic low back pain: Four viewpoints from patients and healthcare providers.

Stenner P, Cross V, McCrum C, McGowan J, Defever E, Lloyd P, Poole R, Moore AP.

Health Psychol Open. 2015 Nov 25;2(2):2055102915615337. doi: 10.1177/2055102915615337. eCollection 2015 Jul.

24.

MicroRNA-26b Modulates the NF-κB Pathway in Alveolar Macrophages by Regulating PTEN.

Zhang L, Huang C, Guo Y, Gou X, Hinsdale M, Lloyd P, Liu L.

J Immunol. 2015 Dec 1;195(11):5404-14. doi: 10.4049/jimmunol.1402933. Epub 2015 Oct 26.

25.

Fluid shear stress upregulates placental growth factor in the vessel wall via NADPH oxidase 4.

Rashdan NA, Lloyd PG.

Am J Physiol Heart Circ Physiol. 2015 Nov 15;309(10):H1655-66. doi: 10.1152/ajpheart.00408.2015. Epub 2015 Sep 25.

26.
27.

Integrated pharmacokinetic, pharmacodynamic and immunogenicity profiling of an anti-CCL21 monoclonal antibody in cynomolgus monkeys.

Dudal S, Subramanian K, Flandre T, Law WS, Lowe PJ, Skerjanec A, Genin JC, Duval M, Piequet A, Cordier A, Jarai G, Van Heeke G, Taplin S, Krantz C, Jones S, Warren AP, Brennan FR, Sims J, Lloyd P.

MAbs. 2015;7(5):829-37. doi: 10.1080/19420862.2015.1060384.

28.

Characteristics of Children in Medicaid Managed Care and Medicaid Fee-for-service, 2003-2005.

Lloyd PC, Simon AE, Parker JD.

Natl Health Stat Report. 2015 Jun 8;(80):1-15.

29.

Postnatal growth rates covary weakly with embryonic development rates and do not explain adult mortality probability among songbirds on four continents.

Martin TE, Oteyza JC, Mitchell AE, Potticary AL, Lloyd P.

Am Nat. 2015 Mar;185(3):380-9. doi: 10.1086/679612. Epub 2015 Jan 22.

PMID:
25674692
30.

Use of generic LC-MS/MS assays to characterize atypical PK profile of a biotherapeutic monoclonal antibody.

Law WS, Genin JC, Miess C, Treton G, Warren AP, Lloyd P, Dudal S, Krantz C.

Bioanalysis. 2014;6(23):3225-35. doi: 10.4155/bio.14.167.

PMID:
25529889
31.

Regulation of myofibroblast differentiation by miR-424 during epithelial-to-mesenchymal transition.

Xiao X, Huang C, Zhao C, Gou X, Senavirathna LK, Hinsdale M, Lloyd P, Liu L.

Arch Biochem Biophys. 2015 Jan 15;566:49-57. doi: 10.1016/j.abb.2014.12.007. Epub 2014 Dec 15.

32.

Ethnic sensitivity assessment - pharmacokinetic comparability between Japanese and non-Japanese healthy subjects on selected mAbs.

Matsushima S, Huang Y, Suzuki H, Nishino J, Lloyd P.

Expert Opin Drug Metab Toxicol. 2015 Feb;11(2):179-91. doi: 10.1517/17425255.2015.990438. Epub 2014 Dec 18.

PMID:
25519513
33.

Pharmacokinetics of serelaxin in patients with hepatic impairment: a single-dose, open-label, parallel group study.

Kobalava Z, Villevalde S, Kotovskaya Y, Hinrichsen H, Petersen-Sylla M, Zaehringer A, Pang Y, Rajman I, Canadi J, Dahlke M, Lloyd P, Halabi A.

Br J Clin Pharmacol. 2015 Jun;79(6):937-45. doi: 10.1111/bcp.12572.

34.

Impact of climate change and population growth on a risk assessment for endocrine disruption in fish due to steroid estrogens in England and Wales.

Keller VDJ, Lloyd P, Terry JA, Williams RJ.

Environ Pollut. 2015 Feb;197:262-268. doi: 10.1016/j.envpol.2014.11.017. Epub 2014 Nov 28.

35.

Safety and tolerability of serelaxin, a recombinant human relaxin-2 in development for the treatment of acute heart failure, in healthy Japanese volunteers and a comparison of pharmacokinetics and pharmacodynamics in healthy Japanese and Caucasian populations.

Dahlke M, Ng D, Yamaguchi M, Machineni S, Berger S, Canadi J, Rajman I, Lloyd P, Pang Y.

J Clin Pharmacol. 2015 Apr;55(4):415-22. doi: 10.1002/jcph.433. Epub 2015 Feb 4.

PMID:
25408331
36.

Eliciting cytotoxic T-lymphocyte responses from synthetic vectors containing one or two epitopes in a C57BL/6 mouse model using peptide-containing biodegradable microspheres and adjuvants.

Rubsamen RM, Herst CV, Lloyd PM, Heckerman DE.

Vaccine. 2014 Jul 16;32(33):4111-6. doi: 10.1016/j.vaccine.2014.05.071. Epub 2014 Jun 7.

37.

Women's experiences after a radical vaginal trachelectomy for early stage cervical cancer. A descriptive phenomenological study.

Lloyd PA, Briggs EV, Kane N, Jeyarajah AR, Shepherd JH.

Eur J Oncol Nurs. 2014 Aug;18(4):362-71. doi: 10.1016/j.ejon.2014.03.014. Epub 2014 May 1.

PMID:
24794078
38.

The ecological and geographic context of morphological and genetic divergence in an understorey-dwelling bird.

Ribeiro ÂM, Lloyd P, Dean WR, Brown M, Bowie RC.

PLoS One. 2014 Feb 7;9(2):e85903. doi: 10.1371/journal.pone.0085903. eCollection 2014.

39.

The effect of birth month on the risk of respiratory syncytial virus hospitalization in the first year of life in the United States.

Lloyd PC, May L, Hoffman D, Riegelman R, Simonsen L.

Pediatr Infect Dis J. 2014 Jun;33(6):e135-40. doi: 10.1097/INF.0000000000000250.

PMID:
24445838
40.

Placenta growth factor and vascular endothelial growth factor a have differential, cell-type specific patterns of expression in vascular cells.

Xiang L, Varshney R, Rashdan NA, Shaw JH, Lloyd PG.

Microcirculation. 2014 Jul;21(5):368-79. doi: 10.1111/micc.12113.

41.

The reference genome sequence of Saccharomyces cerevisiae: then and now.

Engel SR, Dietrich FS, Fisk DG, Binkley G, Balakrishnan R, Costanzo MC, Dwight SS, Hitz BC, Karra K, Nash RS, Weng S, Wong ED, Lloyd P, Skrzypek MS, Miyasato SR, Simison M, Cherry JM.

G3 (Bethesda). 2014 Mar 20;4(3):389-98. doi: 10.1534/g3.113.008995.

42.

Saccharomyces genome database provides new regulation data.

Costanzo MC, Engel SR, Wong ED, Lloyd P, Karra K, Chan ET, Weng S, Paskov KM, Roe GR, Binkley G, Hitz BC, Cherry JM.

Nucleic Acids Res. 2014 Jan;42(Database issue):D717-25. doi: 10.1093/nar/gkt1158. Epub 2013 Nov 21.

43.

Exercise training and peripheral arterial disease.

Haas TL, Lloyd PG, Yang HT, Terjung RL.

Compr Physiol. 2012 Oct;2(4):2933-3017. doi: 10.1002/cphy.c110065. Review.

44.

The impact of culture medium on the development and physiology of biofilms of Pseudomonas fluorescens formed on polyurethane paint.

Crookes-Goodson WJ, Bojanowski CL, Kay ML, Lloyd PF, Blankemeier A, Hurtubise JM, Singh KM, Barlow DE, Ladouceur HD, Matt Eby D, Johnson GR, Mirau PA, Pehrsson PE, Fraser HL, Russell JN Jr.

Biofouling. 2013;29(6):601-15. doi: 10.1080/08927014.2013.783906. Epub 2013 May 22.

PMID:
23697763
45.

A standard method for measuring benzene and formaldehyde emissions from candles in emission test chambers for human health risk assessment purposes.

Petry T, Cazelle E, Lloyd P, Mascarenhas R, Stijntjes G.

Environ Sci Process Impacts. 2013 Jul;15(7):1369-82. doi: 10.1039/c3em00011g.

PMID:
23695106
46.

Evaluation of dried blood spots for the quantification of therapeutic monoclonal antibodies and detection of anti-drug antibodies.

Kaendler K, Warren A, Lloyd P, Sims J, Sickert D.

Bioanalysis. 2013 Mar;5(5):613-22. doi: 10.4155/bio.13.11.

PMID:
23425276
47.

Psoriatic arthritis: an update.

Lloyd P, Ryan C, Menter A.

Arthritis. 2012;2012:176298. doi: 10.1155/2012/176298. Epub 2012 Oct 17.

48.

Post-transcriptional regulation of placenta growth factor mRNA by hydrogen peroxide.

Shaw JH, Lloyd PG.

Microvasc Res. 2012 Sep;84(2):155-60. doi: 10.1016/j.mvr.2012.05.009. Epub 2012 Jun 5.

49.

Caveolin-1, antiapoptosis signaling, and anchorage-independent cell growth. Focus on "Caveolin-1 regulates Mcl-1 stability and anoikis in lung carcinoma cells".

Lloyd PG.

Am J Physiol Cell Physiol. 2012 May 1;302(9):C1282-3. doi: 10.1152/ajpcell.00075.2012. Epub 2012 Mar 14. No abstract available.

50.

Highlights from a recent BIO survey on therapeutic protein-drug interactions.

Pharmacokinetics and Disposition Expert Working Group Drug-Drug Interaction Taskforce, Lloyd P, Zhou H, Theil FP, Kakkar T, Nestorov I, Roberts SA.

J Clin Pharmacol. 2012 Nov;52(11):1755-63. doi: 10.1177/0091270011424144. Epub 2011 Dec 13. No abstract available.

PMID:
22167564

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