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Increasing level of neuromusculoskeletal model personalisation to investigate joint contact forces in cerebral palsy: A twin case study.

Davico G, Pizzolato C, Lloyd DG, Obst SJ, Walsh HPJ, Carty CP.

Clin Biomech (Bristol, Avon). 2019 Dec 18;72:141-149. doi: 10.1016/j.clinbiomech.2019.12.011. [Epub ahead of print]


Neuromusculoskeletal Modeling-Based Prostheses for Recovery After Spinal Cord Injury.

Pizzolato C, Saxby DJ, Palipana D, Diamond LE, Barrett RS, Teng YD, Lloyd DG.

Front Neurorobot. 2019 Dec 2;13:97. doi: 10.3389/fnbot.2019.00097. eCollection 2019. Review.


Modelling the loading mechanics of anterior cruciate ligament.

Nasseri A, Khataee H, Bryant AL, Lloyd DG, Saxby DJ.

Comput Methods Programs Biomed. 2019 Sep 27;184:105098. doi: 10.1016/j.cmpb.2019.105098. [Epub ahead of print]


Best methods and data to reconstruct paediatric lower limb bones for musculoskeletal modelling.

Davico G, Pizzolato C, Killen BA, Barzan M, Suwarganda EK, Lloyd DG, Carty CP.

Biomech Model Mechanobiol. 2019 Nov 5. doi: 10.1007/s10237-019-01245-y. [Epub ahead of print]


Magnetic Resonance Imaging and Freehand 3-D Ultrasound Provide Similar Estimates of Free Achilles Tendon Shape and 3-D Geometry.

Devaprakash D, Lloyd DG, Barrett RS, Obst SJ, Kennedy B, Adams KL, Hunter A, Vlahovich N, Pease DL, Pizzolato C.

Ultrasound Med Biol. 2019 Nov;45(11):2898-2905. doi: 10.1016/j.ultrasmedbio.2019.07.679. Epub 2019 Aug 27.


Development and validation of subject-specific pediatric multibody knee kinematic models with ligamentous constraints.

Barzan M, Modenese L, Carty CP, Maine S, Stockton CA, Sancisi N, Lewis A, Grant J, Lloyd DG, Brito da Luz S.

J Biomech. 2019 Aug 27;93:194-203. doi: 10.1016/j.jbiomech.2019.07.001. Epub 2019 Jul 8.


On-field player workload exposure and knee injury risk monitoring via deep learning.

Johnson WR, Mian A, Lloyd DG, Alderson JA.

J Biomech. 2019 Aug 27;93:185-193. doi: 10.1016/j.jbiomech.2019.07.002. Epub 2019 Jul 8.


Tibiofemoral joint structural change from 2.5 to 4.5 years following ACL reconstruction with and without combined meniscal pathology.

Wang X, Bennell KL, Wang Y, Wrigley TV, Van Ginckel A, Fortin K, Saxby DJ, Cicuttini FM, Lloyd DG, Vertullo CJ, Feller JA, Whitehead T, Gallie P, Bryant AL.

BMC Musculoskelet Disord. 2019 Jul 4;20(1):312. doi: 10.1186/s12891-019-2687-9.


Establishing outcome measures in early knee osteoarthritis.

Emery CA, Whittaker JL, Mahmoudian A, Lohmander LS, Roos EM, Bennell KL, Toomey CM, Reimer RA, Thompson D, Ronsky JL, Kuntze G, Lloyd DG, Andriacchi T, Englund M, Kraus VB, Losina E, Bierma-Zeinstra S, Runhaar J, Peat G, Luyten FP, Snyder-Mackler L, Risberg MA, Mobasheri A, Guermazi A, Hunter DJ, Arden NK.

Nat Rev Rheumatol. 2019 Jul;15(7):438-448. doi: 10.1038/s41584-019-0237-3. Epub 2019 Jun 14. Review.


The effects of electromyography-assisted modelling in estimating musculotendon forces during gait in children with cerebral palsy.

Veerkamp K, Schallig W, Harlaar J, Pizzolato C, Carty CP, Lloyd DG, van der Krogt MM.

J Biomech. 2019 Jul 19;92:45-53. doi: 10.1016/j.jbiomech.2019.05.026. Epub 2019 May 22.


Statistical shape modelling versus linear scaling: Effects on predictions of hip joint centre location and muscle moment arms in people with hip osteoarthritis.

Bahl JS, Zhang J, Killen BA, Taylor M, Solomon LB, Arnold JB, Lloyd DG, Besier TF, Thewlis D.

J Biomech. 2019 Mar 6;85:164-172. doi: 10.1016/j.jbiomech.2019.01.031. Epub 2019 Jan 24.


Minimal medical imaging can accurately reconstruct geometric bone models for musculoskeletal models.

Suwarganda EK, Diamond LE, Lloyd DG, Besier TF, Zhang J, Killen BA, Savage TN, Saxby DJ.

PLoS One. 2019 Feb 11;14(2):e0205628. doi: 10.1371/journal.pone.0205628. eCollection 2019.


Primarily hip-borne load carriage does not alter biomechanical risk factors for overuse injuries in soldiers.

Lenton GK, Saxby DJ, Lloyd DG, Billing D, Higgs J, Doyle TLA.

J Sci Med Sport. 2019 Feb;22(2):158-163. doi: 10.1016/j.jsams.2018.06.013. Epub 2018 Jun 28.


A calibrated EMG-informed neuromusculoskeletal model can appropriately account for muscle co-contraction in the estimation of hip joint contact forces in people with hip osteoarthritis.

Hoang HX, Diamond LE, Lloyd DG, Pizzolato C.

J Biomech. 2019 Jan 23;83:134-142. doi: 10.1016/j.jbiomech.2018.11.042. Epub 2018 Nov 29.


Lower-limb joint work and power are modulated during load carriage based on load configuration and walking speed.

Lenton GK, Doyle TLA, Lloyd DG, Higgs J, Billing D, Saxby DJ.

J Biomech. 2019 Jan 23;83:174-180. doi: 10.1016/j.jbiomech.2018.11.036. Epub 2018 Nov 29.


Different visual stimuli affect muscle activation at the knee during sidestepping.

Lee MJC, Lloyd DG, Lay BS, Bourke PD, Alderson JA.

J Sports Sci. 2019 May;37(10):1123-1128. doi: 10.1080/02640414.2018.1545276. Epub 2018 Nov 19.


Influence of altered geometry and material properties on tissue stress distribution under load in tendinopathic Achilles tendons - A subject-specific finite element analysis.

Shim VB, Hansen W, Newsham-West R, Nuri L, Obst S, Pizzolato C, Lloyd DG, Barrett RS.

J Biomech. 2019 Jan 3;82:142-148. doi: 10.1016/j.jbiomech.2018.10.027. Epub 2018 Oct 28.


Cancellous bone and theropod dinosaur locomotion. Part II-a new approach to inferring posture and locomotor biomechanics in extinct tetrapod vertebrates.

Bishop PJ, Hocknull SA, Clemente CJ, Hutchinson JR, Barrett RS, Lloyd DG.

PeerJ. 2018 Oct 31;6:e5779. doi: 10.7717/peerj.5779. eCollection 2018.


Cancellous bone and theropod dinosaur locomotion. Part I-an examination of cancellous bone architecture in the hindlimb bones of theropods.

Bishop PJ, Hocknull SA, Clemente CJ, Hutchinson JR, Farke AA, Beck BR, Barrett RS, Lloyd DG.

PeerJ. 2018 Oct 31;6:e5778. doi: 10.7717/peerj.5778. eCollection 2018.


Cancellous bone and theropod dinosaur locomotion. Part III-Inferring posture and locomotor biomechanics in extinct theropods, and its evolution on the line to birds.

Bishop PJ, Hocknull SA, Clemente CJ, Hutchinson JR, Farke AA, Barrett RS, Lloyd DG.

PeerJ. 2018 Oct 31;6:e5777. doi: 10.7717/peerj.5777. eCollection 2018.


Tibiofemoral joint contact forces increase with load magnitude and walking speed but remain almost unchanged with different types of carried load.

Lenton GK, Bishop PJ, Saxby DJ, Doyle TLA, Pizzolato C, Billing D, Lloyd DG.

PLoS One. 2018 Nov 5;13(11):e0206859. doi: 10.1371/journal.pone.0206859. eCollection 2018.


Cysteines and Disulfide-Bridged Macrocyclic Mimics of Teixobactin Analogues and Their Antibacterial Activity Evaluation against Methicillin-Resistant Staphylococcus Aureus (MRSA).

Malkawi R, Iyer A, Parmar A, Lloyd DG, Leng Goh ET, Taylor EJ, Sarmad S, Madder A, Lakshminarayanan R, Singh I.

Pharmaceutics. 2018 Oct 11;10(4). pii: E183. doi: 10.3390/pharmaceutics10040183.


Combining in silico and in vitro experiments to characterize the role of fascicle twist in the Achilles tendon.

Shim VB, Handsfield GG, Fernandez JW, Lloyd DG, Besier TF.

Sci Rep. 2018 Sep 14;8(1):13856. doi: 10.1038/s41598-018-31587-z.


Controlled ecological evaluation of an implemented exercise-training programme to prevent lower limb injuries in sport: population-level trends in hospital-treated injuries.

Finch CF, Gray SE, Akram M, Donaldson A, Lloyd DG, Cook JL.

Br J Sports Med. 2019 Apr;53(8):487-492. doi: 10.1136/bjsports-2018-099488. Epub 2018 Sep 14.


Subject-specific calibration of neuromuscular parameters enables neuromusculoskeletal models to estimate physiologically plausible hip joint contact forces in healthy adults.

Hoang HX, Pizzolato C, Diamond LE, Lloyd DG.

J Biomech. 2018 Oct 26;80:111-120. doi: 10.1016/j.jbiomech.2018.08.023. Epub 2018 Aug 29.


Individual muscle contributions to tibiofemoral compressive articular loading during walking, running and sidestepping.

Killen BA, Saxby DJ, Fortin K, Gardiner BS, Wrigley TV, Bryant AL, Lloyd DG.

J Biomech. 2018 Oct 26;80:23-31. doi: 10.1016/j.jbiomech.2018.08.022. Epub 2018 Aug 23.


Finding the sweet spot via personalised Achilles tendon training: the future is within reach.

Pizzolato C, Lloyd DG, Zheng MH, Besier TF, Shim VB, Obst SJ, Newsham-West R, Saxby DJ, Barrett RS.

Br J Sports Med. 2019 Jan;53(1):11-12. doi: 10.1136/bjsports-2018-099020. Epub 2018 Jul 20. No abstract available.


Greater magnitude tibiofemoral contact forces are associated with reduced prevalence of osteochondral pathologies 2-3 years following anterior cruciate ligament reconstruction.

Saxby DJ, Bryant AL, Van Ginckel A, Wang Y, Wang X, Modenese L, Gerus P, Konrath JM, Fortin K, Wrigley TV, Bennell KL, Cicuttini FM, Vertullo C, Feller JA, Whitehead T, Gallie P, Lloyd DG.

Knee Surg Sports Traumatol Arthrosc. 2019 Mar;27(3):707-715. doi: 10.1007/s00167-018-5006-3. Epub 2018 Jun 7.


Controlled ecological evaluation of an implemented exercise training programme to prevent lower limb injuries in sport: differences in implementation activity.

Donaldson A, Gabbe BJ, Lloyd DG, Cook J, Finch CF.

Inj Prev. 2019 Dec;25(6):480-486. doi: 10.1136/injuryprev-2017-042579. Epub 2018 Apr 24.


Teixobactin analogues reveal enduracididine to be non-essential for highly potent antibacterial activity and lipid II binding.

Parmar A, Iyer A, Prior SH, Lloyd DG, Leng Goh ET, Vincent CS, Palmai-Pallag T, Bachrati CZ, Breukink E, Madder A, Lakshminarayanan R, Taylor EJ, Singh I.

Chem Sci. 2017 Dec 1;8(12):8183-8192. doi: 10.1039/c7sc03241b. Epub 2017 Oct 5.


The influence of speed and size on avian terrestrial locomotor biomechanics: Predicting locomotion in extinct theropod dinosaurs.

Bishop PJ, Graham DF, Lamas LP, Hutchinson JR, Rubenson J, Hancock JA, Wilson RS, Hocknull SA, Barrett RS, Lloyd DG, Clemente CJ.

PLoS One. 2018 Feb 21;13(2):e0192172. doi: 10.1371/journal.pone.0192172. eCollection 2018.


Next generation high throughput DNA damage detection platform for genotoxic compound screening.

Sykora P, Witt KL, Revanna P, Smith-Roe SL, Dismukes J, Lloyd DG, Engelward BP, Sobol RW.

Sci Rep. 2018 Feb 9;8(1):2771. doi: 10.1038/s41598-018-20995-w.


Design and Syntheses of Highly Potent Teixobactin Analogues against Staphylococcus aureus, Methicillin-Resistant Staphylococcus aureus (MRSA), and Vancomycin-Resistant Enterococci (VRE) in Vitro and in Vivo.

Parmar A, Lakshminarayanan R, Iyer A, Mayandi V, Leng Goh ET, Lloyd DG, Chalasani MLS, Verma NK, Prior SH, Beuerman RW, Madder A, Taylor EJ, Singh I.

J Med Chem. 2018 Mar 8;61(5):2009-2017. doi: 10.1021/acs.jmedchem.7b01634. Epub 2018 Feb 15.


Cartilage quantitative T2 relaxation time 2-4 years following isolated anterior cruciate ligament reconstruction.

Wang X, Wrigley TV, Bennell KL, Wang Y, Fortin K, Cicuttini FM, Lloyd DG, Bryant AL.

J Orthop Res. 2018 Jul;36(7):2022-2029. doi: 10.1002/jor.23846. Epub 2018 Jan 24.


Bioinspired Technologies to Connect Musculoskeletal Mechanobiology to the Person for Training and Rehabilitation.

Pizzolato C, Lloyd DG, Barrett RS, Cook JL, Zheng MH, Besier TF, Saxby DJ.

Front Comput Neurosci. 2017 Oct 18;11:96. doi: 10.3389/fncom.2017.00096. eCollection 2017. Review.


Muscle contributions to the acceleration of the whole body centre of mass during recovery from forward loss of balance by stepping in young and older adults.

Graham DF, Carty CP, Lloyd DG, Barrett RS.

PLoS One. 2017 Oct 25;12(10):e0185564. doi: 10.1371/journal.pone.0185564. eCollection 2017.


Protocol for a multi-centre randomised controlled trial comparing arthroscopic hip surgery to physiotherapy-led care for femoroacetabular impingement (FAI): the Australian FASHIoN trial.

Murphy NJ, Eyles J, Bennell KL, Bohensky M, Burns A, Callaghan FM, Dickenson E, Fary C, Grieve SM, Griffin DR, Hall M, Hobson R, Kim YJ, Linklater JM, Lloyd DG, Molnar R, O'Connell RL, O'Donnell J, O'Sullivan M, Randhawa S, Reichenbach S, Saxby DJ, Singh P, Spiers L, Tran P, Wrigley TV, Hunter DJ.

BMC Musculoskelet Disord. 2017 Sep 26;18(1):406. doi: 10.1186/s12891-017-1767-y.


Integrating a hip belt with body armour reduces the magnitude and changes the location of shoulder pressure and perceived discomfort in soldiers.

Lenton GK, Doyle TLA, Saxby DJ, Billing D, Higgs J, Lloyd DG.

Ergonomics. 2018 Apr;61(4):566-575. doi: 10.1080/00140139.2017.1381278. Epub 2017 Oct 24.


Relationships Between Tibiofemoral Contact Forces and Cartilage Morphology at 2 to 3 Years After Single-Bundle Hamstring Anterior Cruciate Ligament Reconstruction and in Healthy Knees.

Young People With Old Knees Research Team, Saxby DJ, Bryant AL, Wang X, Modenese L, Gerus P, Konrath JM, Bennell KL, Fortin K, Wrigley T, Cicuttini FM, Vertullo CJ, Feller JA, Whitehead T, Gallie P, Lloyd DG.

Orthop J Sports Med. 2017 Aug 31;5(8):2325967117722506. doi: 10.1177/2325967117722506. eCollection 2017 Aug.


Prolonged running increases knee moments in sidestepping and cutting manoeuvres in sport.

Savage RJ, Lay BS, Wills JA, Lloyd DG, Doyle TLA.

J Sci Med Sport. 2018 May;21(5):508-512. doi: 10.1016/j.jsams.2017.07.007. Epub 2017 Jul 14.


Using step width to compare locomotor biomechanics between extinct, non-avian theropod dinosaurs and modern obligate bipeds.

Bishop PJ, Clemente CJ, Weems RE, Graham DF, Lamas LP, Hutchinson JR, Rubenson J, Wilson RS, Hocknull SA, Barrett RS, Lloyd DG.

J R Soc Interface. 2017 Jul;14(132). pii: 20170276. doi: 10.1098/rsif.2017.0276.


Syntheses of potent teixobactin analogues against methicillin-resistant Staphylococcus aureus (MRSA) through the replacement of l-allo-enduracididine with its isosteres.

Parmar A, Iyer A, Lloyd DG, Vincent CS, Prior SH, Madder A, Taylor EJ, Singh I.

Chem Commun (Camb). 2017 Jul 6;53(55):7788-7791. doi: 10.1039/c7cc04021k.


Effects of hip joint centre mislocation on gait kinematics of children with cerebral palsy calculated using patient-specific direct and inverse kinematic models.

Kainz H, Carty CP, Maine S, Walsh HPJ, Lloyd DG, Modenese L.

Gait Posture. 2017 Sep;57:154-160. doi: 10.1016/j.gaitpost.2017.06.002. Epub 2017 Jun 4.


Design, Synthesis and Biochemical Evaluation of Novel Selective Estrogen Receptor Ligand Conjugates Incorporating an Endoxifen-Combretastatin Hybrid Scaffold.

Keely NO, Carr M, Yassin B, Ana G, Lloyd DG, Zisterer D, Meegan MJ.

Biomedicines. 2016 Jul 20;4(3). pii: E15. doi: 10.3390/biomedicines4030015.


Biofeedback for Gait Retraining Based on Real-Time Estimation of Tibiofemoral Joint Contact Forces.

Pizzolato C, Reggiani M, Saxby DJ, Ceseracciu E, Modenese L, Lloyd DG.

IEEE Trans Neural Syst Rehabil Eng. 2017 Sep;25(9):1612-1621. doi: 10.1109/TNSRE.2017.2683488. Epub 2017 Apr 18.


Muscle contributions to medial tibiofemoral compartment contact loading following ACL reconstruction using semitendinosus and gracilis tendon grafts.

Konrath JM, Saxby DJ, Killen BA, Pizzolato C, Vertullo CJ, Barrett RS, Lloyd DG.

PLoS One. 2017 Apr 19;12(4):e0176016. doi: 10.1371/journal.pone.0176016. eCollection 2017.


Knee Biomechanics During Jogging After Arthroscopic Partial Meniscectomy: A Longitudinal Study.

Hall M, Wrigley TV, Metcalf BR, Hinman RS, Cicuttini FM, Dempsey AR, Lloyd DG, Bennell KL.

Am J Sports Med. 2017 Jul;45(8):1872-1880. doi: 10.1177/0363546517698934. Epub 2017 Apr 18.


Reliability of four models for clinical gait analysis.

Kainz H, Graham D, Edwards J, Walsh HPJ, Maine S, Boyd RN, Lloyd DG, Modenese L, Carty CP.

Gait Posture. 2017 May;54:325-331. doi: 10.1016/j.gaitpost.2017.04.001. Epub 2017 Apr 3.


An alternative whole-body marker set to accurately and reliably quantify joint kinematics during load carriage.

Lenton GK, Doyle TLA, Saxby DJ, Lloyd DG.

Gait Posture. 2017 May;54:318-324. doi: 10.1016/j.gaitpost.2017.04.002. Epub 2017 Apr 2.


Achilles tendon stress is more sensitive to subject-specific geometry than subject-specific material properties: A finite element analysis.

Hansen W, Shim VB, Obst S, Lloyd DG, Newsham-West R, Barrett RS.

J Biomech. 2017 May 3;56:26-31. doi: 10.1016/j.jbiomech.2017.02.031. Epub 2017 Mar 4.


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