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Incidence of early major adverse events after surgery in moderate-risk patients: early postoperative adverse events.

Lloyd C, Proctor L, Au M, Story D, Edwards S, Ludbrook G.

Br J Anaesth. 2019 Nov 6. pii: S0007-0912(19)30769-X. doi: 10.1016/j.bja.2019.10.002. [Epub ahead of print] No abstract available.


Neutrophils restrain allergic airway inflammation by limiting ILC2 function and monocyte-dendritic cell antigen presentation.

Patel DF, Peiró T, Bruno N, Vuononvirta J, Akthar S, Puttur F, Pyle CJ, Suveizdytė K, Walker SA, Singanayagam A, Carlin LM, Gregory LG, Lloyd CM, Snelgrove RJ.

Sci Immunol. 2019 Nov 8;4(41). pii: eaax7006. doi: 10.1126/sciimmunol.aax7006.


Untargeted characterisation of dissolved organic matter contributions to rivers from anthropogenic point sources using direct infusion- and high-performance liquid chromatography-Orbitrap mass spectrometry.

Pemberton JA, Lloyd CEM, Arthur CJ, Johnes PJ, Dickinson M, Charlton AJ, Evershed RP.

Rapid Commun Mass Spectrom. 2019 Nov 2. doi: 10.1002/rcm.8618. [Epub ahead of print]


Effect of procedural refinement of transfemoral transcatheter aortic valve implantation on outcomes and costs: a single-centre retrospective study.

Sangaraju S, Cox I, Dalrymple-Hay M, Lloyd C, Suresh V, Riches T, Melhuish S, Asopa S, Newcombe S, Deutsch C, Bramlage P.

Open Heart. 2019 Oct 3;6(2):e001064. doi: 10.1136/openhrt-2019-001064. eCollection 2019.


Global spatio-temporally harmonised datasets for producing high-resolution gridded population distribution datasets.

Lloyd CT, Chamberlain H, Kerr D, Yetman G, Pistolesi L, Stevens FR, Gaughan AE, Nieves JJ, Hornby G, MacManus K, Sinha P, Bondarenko M, Sorichetta A, Tatem AJ.

Big Earth Data. 2019 Jun 18;3(2):108-139. doi: 10.1080/20964471.2019.1625151. eCollection 2019.


Exogenous Keratinocyte Growth Factor Is Not Required for Pigmentation of Skin Substitutes with Three Isogeneic Cell Types.

Boyce ST, Supp DM, Lloyd CM.

Tissue Eng Part A. 2019 Nov 1. doi: 10.1089/ten.TEA.2019.0203. [Epub ahead of print]


More anxious than depressed: prevalence and correlates in a 15-nation study of anxiety disorders in people with type 2 diabetes mellitus.

Chaturvedi SK, Manche Gowda S, Ahmed HU, Alosaimi FD, Andreone N, Bobrov A, Bulgari V, Carrà G, Castelnuovo G, de Girolamo G, Gondek T, Jovanovic N, Kamala T, Kiejna A, Lalic N, Lecic-Tosevski D, Minhas F, Mutiso V, Ndetei D, Rabbani G, Somruk S, Srikanta S, Taj R, Valentini U, Vukovic O, Wölwer W, Cimino L, Nouwen A, Lloyd C, Sartorius N.

Gen Psychiatr. 2019 Aug 9;32(4):e100076. doi: 10.1136/gpsych-2019-100076. eCollection 2019.


Nutrient enrichment induces a shift in dissolved organic carbon (DOC) metabolism in oligotrophic freshwater sediments.

Brailsford FL, Glanville HC, Golyshin PN, Marshall MR, Lloyd CE, Johnes PJ, Jones DL.

Sci Total Environ. 2019 Nov 10;690:1131-1139. doi: 10.1016/j.scitotenv.2019.07.054. Epub 2019 Jul 4.


Age and motivation can be specific responsivity features that moderate the relationship between risk and rehabilitation outcome.

Higley CA, Lloyd CD, Serin RC.

Law Hum Behav. 2019 Aug 29. doi: 10.1037/lhb0000348. [Epub ahead of print]


A T cell-myeloid IL-10 axis regulates pathogenic IFN-γ-dependent immunity in a mouse model of type 2-low asthma.

Branchett WJ, Stölting H, Oliver RA, Walker SA, Puttur F, Gregory LG, Gabryšová L, Wilson MS, O'Garra A, Lloyd CM.

J Allergy Clin Immunol. 2019 Aug 22. pii: S0091-6749(19)31079-6. doi: 10.1016/j.jaci.2019.08.006. [Epub ahead of print]


Preclinical development of a high affinity α-synuclein antibody, MEDI1341, that can enter the brain, sequester extracellular α-synuclein and attenuate α-synuclein spreading in vivo.

Schofield DJ, Irving L, Calo L, Bogstedt A, Rees G, Nuccitelli A, Narwal R, Petrone M, Roberts J, Brown L, Cusdin F, Dosanjh B, Lloyd C, Dobson C, Gurrell I, Fraser G, McFarlane M, Rockenstein E, Spencer B, Masliah E, Spillantini MG, Tan K, Billinton A, Vaughan T, Chessell I, Perkinton MS.

Neurobiol Dis. 2019 Dec;132:104582. doi: 10.1016/j.nbd.2019.104582. Epub 2019 Aug 21.


Opening the Window of Immune Opportunity: Treating Childhood Asthma.

Lloyd CM, Saglani S.

Trends Immunol. 2019 Sep;40(9):786-798. doi: 10.1016/ Epub 2019 Aug 14. Review.


The need for further oral health research surrounding the provision of dental treatment for people with drug dependency.

Bowes C, Page G, Wassall R, Lloyd C.

Br Dent J. 2019 Jul;227(1):58-60. doi: 10.1038/s41415-019-0469-2.


Cellular responses to reactive oxygen species are predicted from molecular mechanisms.

Yang L, Mih N, Anand A, Park JH, Tan J, Yurkovich JT, Monk JM, Lloyd CJ, Sandberg TE, Seo SW, Kim D, Sastry AV, Phaneuf P, Gao Y, Broddrick JT, Chen K, Heckmann D, Szubin R, Hefner Y, Feist AM, Palsson BO.

Proc Natl Acad Sci U S A. 2019 Jul 9;116(28):14368-14373. doi: 10.1073/pnas.1905039116. Epub 2019 Jul 3.


Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases.

Singhania A, Graham CM, Gabryšová L, Moreira-Teixeira L, Stavropoulos E, Pitt JM, Chakravarty P, Warnatsch A, Branchett WJ, Conejero L, Lin JW, Davidson S, Wilson MS, Bancroft G, Langhorne J, Frickel E, Sesay AK, Priestnall SL, Herbert E, Ioannou M, Wang Q, Humphreys IR, Dodd J, Openshaw PJM, Mayer-Barber KD, Jankovic D, Sher A, Lloyd CM, Baldwin N, Chaussabel D, Papayannopoulos V, Wack A, Banchereau JF, Pascual VM, O'Garra A.

Nat Commun. 2019 Jun 28;10(1):2887. doi: 10.1038/s41467-019-10601-6.


Capital depreciation: The lack of recovery capital and post-release support for prisoners leaving the Drug Recovery Wings in England and Wales.

Lloyd C, Page G, McKeganey N, Russell C.

Int J Drug Policy. 2019 Aug;70:107-116. doi: 10.1016/j.drugpo.2019.06.012. Epub 2019 Jun 22.


Curated Collections for Clinician Educators: Five Key Papers on Graduated Responsibility in Residency Education.

Schnapp BH, Caretta-Weyer HA, Cortez E, Heinrich SA, Kraut AS, Lloyd CM, Silvester C, Sorge RM, Wain A, Gottlieb M.

Cureus. 2019 Apr 4;11(4):e4383. doi: 10.7759/cureus.4383.


Response to Comment on "An extracellular matrix fragment drives epithelial remodeling and airway hyperresponsiveness".

Patel DF, Gaggar A, Blalock JE, Gregory LG, Lloyd CM, Snelgrove RJ.

Sci Transl Med. 2019 Jun 19;11(497). pii: eaaw0462. doi: 10.1126/scitranslmed.aaw0462.


The appropriateness of psychotropic medicines: an interview study of service users attending a substance misuse service in England.

Oluyase AO, Raistrick D, Hughes E, Lloyd C.

Int J Clin Pharm. 2019 Aug;41(4):972-980. doi: 10.1007/s11096-019-00861-z. Epub 2019 Jun 13.


Can venous cannula design influence venous return and negative pressure with a minimally invasive extracorporeal circulation?

Bennett MJ, Hodgkiss S, Lloyd CT, Webb G.

Int J Artif Organs. 2019 Dec;42(12):704-710. doi: 10.1177/0391398819854766. Epub 2019 Jun 13.


Abnormal pro-gly-pro pathway and airway neutrophilia in pediatric cystic fibrosis.

Turnbull AR, Pyle CJ, Patel DF, Jackson PL, Hilliard TN, Regamey N, Tan HL, Brown S, Thursfield R, Short C, Mc Fie M, Alton EWFW, Gaggar A, Blalock JE, Lloyd CM, Bush A, Davies JC, Snelgrove RJ.

J Cyst Fibros. 2019 Jun 5. pii: S1569-1993(19)30769-6. doi: 10.1016/j.jcf.2019.05.017. [Epub ahead of print]


Pulmonary environmental cues drive group 2 innate lymphoid cell dynamics in mice and humans.

Puttur F, Denney L, Gregory LG, Vuononvirta J, Oliver R, Entwistle LJ, Walker SA, Headley MB, McGhee EJ, Pease JE, Krummel MF, Carlin LM, Lloyd CM.

Sci Immunol. 2019 Jun 7;4(36). pii: eaav7638. doi: 10.1126/sciimmunol.aav7638.


Pulmonary type-2 innate lymphoid cells in paediatric severe asthma: phenotype and response to steroids.

Nagakumar P, Puttur F, Gregory LG, Denney L, Fleming L, Bush A, Lloyd CM, Saglani S.

Eur Respir J. 2019 Aug 29;54(2). pii: 1801809. doi: 10.1183/13993003.01809-2018. Print 2019 Aug.


The Transferrin Receptor CD71 Delineates Functionally Distinct Airway Macrophage Subsets during Idiopathic Pulmonary Fibrosis.

Allden SJ, Ogger PP, Ghai P, McErlean P, Hewitt R, Toshner R, Walker SA, Saunders P, Kingston S, Molyneaux PL, Maher TM, Lloyd CM, Byrne AJ.

Am J Respir Crit Care Med. 2019 Jul 15;200(2):209-219. doi: 10.1164/rccm.201809-1775OC.


BOFdat: Generating biomass objective functions for genome-scale metabolic models from experimental data.

Lachance JC, Lloyd CJ, Monk JM, Yang L, Sastry AV, Seif Y, Palsson BO, Rodrigue S, Feist AM, King ZA, Jacques PÉ.

PLoS Comput Biol. 2019 Apr 22;15(4):e1006971. doi: 10.1371/journal.pcbi.1006971. eCollection 2019 Apr.


Regulatory cytokine function in the respiratory tract.

Branchett WJ, Lloyd CM.

Mucosal Immunol. 2019 May;12(3):589-600. doi: 10.1038/s41385-019-0158-0. Epub 2019 Mar 15. Review.


Predicting proteome allocation, overflow metabolism, and metal requirements in a model acetogen.

Liu JK, Lloyd C, Al-Bassam MM, Ebrahim A, Kim JN, Olson C, Aksenov A, Dorrestein P, Zengler K.

PLoS Comput Biol. 2019 Mar 7;15(3):e1006848. doi: 10.1371/journal.pcbi.1006848. eCollection 2019 Mar.


Identification of Merkel cells associated with neurons in engineered skin substitutes after grafting to full thickness wounds.

Hahn JM, Combs KA, Lloyd CM, McFarland KL, Boyce ST, Supp DM.

PLoS One. 2019 Mar 5;14(3):e0213325. doi: 10.1371/journal.pone.0213325. eCollection 2019.


The genetic basis for adaptation of model-designed syntrophic co-cultures.

Lloyd CJ, King ZA, Sandberg TE, Hefner Y, Olson CA, Phaneuf PV, O'Brien EJ, Sanders JG, Salido RA, Sanders K, Brennan C, Humphrey G, Knight R, Feist AM.

PLoS Comput Biol. 2019 Mar 1;15(3):e1006213. doi: 10.1371/journal.pcbi.1006213. eCollection 2019 Mar.


Comment on the consensus report on the management of hyperglycaemia in Type 2 diabetes by the American Diabetes Association and the European Association for the Study of Diabetes.

Skinner T, Byrne M, Dickinson JK, Fisher L, Funnell M, Guzman S, Hendrieckx C, Hermanns N, Kanc K, Lloyd C, Mocan A, Nouwen A, Pouwer F, Saleh-Stattin N, Snoek F, Speight J, Sturt J, Vallis M, Wagner J, Willaing I, Young-Hyman D, Zoffmann V.

Diabet Med. 2019 Jul;36(7):911-912. doi: 10.1111/dme.13934. Epub 2019 Apr 3. No abstract available.


Airway macrophages as the guardians of tissue repair in the lung.

Puttur F, Gregory LG, Lloyd CM.

Immunol Cell Biol. 2019 Mar;97(3):246-257. doi: 10.1111/imcb.12235. Epub 2019 Feb 15. Review.


Regulation of ectodomain shedding of ADAM33 in vitro and in vivo.

Davies ER, Denney L, Wandel M, Lloyd CM, Davies DE, Haitchi HM.

J Allergy Clin Immunol. 2019 Jun;143(6):2281-2284.e3. doi: 10.1016/j.jaci.2019.01.026. Epub 2019 Feb 2. No abstract available.


The relation between adverse childhood experiences and moral injury in the Canadian Armed Forces.

Battaglia AM, Protopopescu A, Boyd JE, Lloyd C, Jetly R, O'Connor C, Hood HK, Nazarov A, Rhind SG, Lanius RA, McKinnon MC.

Eur J Psychotraumatol. 2019 Jan 17;10(1):1546084. doi: 10.1080/20008198.2018.1546084. eCollection 2019.


Tests for noninferiority trials with binomial endpoints: A guide to modern and quasi-exact methods for biomedical researchers.

Ripamonti E, Lloyd CJ.

Pharm Stat. 2019 May;18(3):377-387. doi: 10.1002/pst.1929. Epub 2019 Jan 28.


DynamicME: dynamic simulation and refinement of integrated models of metabolism and protein expression.

Yang L, Ebrahim A, Lloyd CJ, Saunders MA, Palsson BO.

BMC Syst Biol. 2019 Jan 9;13(1):2. doi: 10.1186/s12918-018-0675-6.


Lower airway microbiota associates with inflammatory phenotype in severe preschool wheeze.

Robinson PFM, Pattaroni C, Cook J, Gregory L, Alonso AM, Fleming LJ, Lloyd CM, Bush A, Marsland BJ, Saglani S.

J Allergy Clin Immunol. 2019 Apr;143(4):1607-1610.e3. doi: 10.1016/j.jaci.2018.12.985. Epub 2018 Dec 21. No abstract available.


Machine learning applied to enzyme turnover numbers reveals protein structural correlates and improves metabolic models.

Heckmann D, Lloyd CJ, Mih N, Ha Y, Zielinski DC, Haiman ZB, Desouki AA, Lercher MJ, Palsson BO.

Nat Commun. 2018 Dec 7;9(1):5252. doi: 10.1038/s41467-018-07652-6.


A spatial analysis of health status in Britain, 1991-2011.

Dearden EK, Lloyd CD, Catney G.

Soc Sci Med. 2019 Jan;220:340-352. doi: 10.1016/j.socscimed.2018.11.014. Epub 2018 Nov 14.


Epidemiology and natural history of hepatitis C virus infection among children and young people.

Modin L, Arshad A, Wilkes B, Benselin J, Lloyd C, Irving WL, Kelly DA.

J Hepatol. 2019 Mar;70(3):371-378. doi: 10.1016/j.jhep.2018.11.013. Epub 2018 Nov 27.


Participatory and Action Research Within and Beyond the Academy: Contesting Racism through Decolonial Praxis and Teaching "Against the Grain".

Lykes MB, Lloyd CR, Nicholson KM.

Am J Community Psychol. 2018 Dec;62(3-4):406-418. doi: 10.1002/ajcp.12290. Epub 2018 Nov 26.


Determining the sources of nutrient flux to water in headwater catchments: Examining the speciation balance to inform the targeting of mitigation measures.

Lloyd CEM, Johnes PJ, Freer JE, Carswell AM, Jones JI, Stirling MW, Hodgkinson RA, Richmond C, Collins AL.

Sci Total Environ. 2019 Jan 15;648:1179-1200. doi: 10.1016/j.scitotenv.2018.08.190. Epub 2018 Aug 18.


The ORMDL3 Asthma Gene Regulates ICAM1 and Has Multiple Effects on Cellular Inflammation.

Zhang Y, Willis-Owen SAG, Spiegel S, Lloyd CM, Moffatt MF, Cookson WOCM.

Am J Respir Crit Care Med. 2019 Feb 15;199(4):478-488. doi: 10.1164/rccm.201803-0438OC.


Youth-focused group mindfulness-based intervention in individuals with early psychosis: A randomized pilot feasibility study.

MacDougall AG, Price E, Vandermeer MRJ, Lloyd C, Bird R, Sethi R, Shanmugalingam A, Carr J, Anderson KK, Norman RMG.

Early Interv Psychiatry. 2019 Aug;13(4):993-998. doi: 10.1111/eip.12753. Epub 2018 Oct 15.


Targeting the ICOS/ICOS-L pathway in a mouse model of established allergic asthma disrupts T follicular helper cell responses and ameliorates disease.

Uwadiae FI, Pyle CJ, Walker SA, Lloyd CM, Harker JA.

Allergy. 2019 Apr;74(4):650-662. doi: 10.1111/all.13602. Epub 2018 Nov 12.


Inception of early-life allergen-induced airway hyperresponsiveness is reliant on IL-13+CD4+ T cells.

Saglani S, Gregory LG, Manghera AK, Branchett WJ, Uwadiae F, Entwistle LJ, Oliver RA, Vasiliou JE, Sherburn R, Lui S, Puttur F, Vöhringer D, Walker SA, Buckley J, Grychtol R, Fainardi V, Denney L, Byrne A, von Mutius E, Bush A, Lloyd CM.

Sci Immunol. 2018 Sep 7;3(27). pii: eaan4128. doi: 10.1126/sciimmunol.aan4128.


Transapical valve-in-ring mitral valve implantation through the anterior mitral valve leaflet.

Rogers L, Villaquiran J, Cox I, Dalrymple-Hay M, Lloyd C.

Multimed Man Cardiothorac Surg. 2018 Aug 28;2018. doi: 10.1510/mmcts.2018.031.


Pulmonary epithelial barrier and immunological functions at birth and in early life - key determinants of the development of asthma?  A description of the protocol for the Breathing Together study.

Turner S, Custovic A, Ghazal P, Grigg J, Gore M, Henderson J, Lloyd CM, Marsland B, Power UF, Roberts G, Saglani S, Schwarze J, Shields M, Bush A.

Wellcome Open Res. 2018 May 17;3:60. doi: 10.12688/wellcomeopenres.14489.1. eCollection 2018.

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