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Structure-guided enhancement of selectivity of chemical probe inhibitors targeting bacterial seryl-tRNA synthetase.

Cain R, Salimraj R, Punekar A, Belini D, Fishwick CWG, Czaplewski L, Scott DJ, Harris G, Dowson CG, Lloyd AJ, Roper DI.

J Med Chem. 2019 Oct 18. doi: 10.1021/acs.jmedchem.9b01131. [Epub ahead of print]


Defining Global Benchmarks in Bariatric Surgery: A Retrospective Multicenter Analysis of Minimally Invasive Roux-en-Y Gastric Bypass and Sleeve Gastrectomy.

Gero D, Raptis DA, Vleeschouwers W, van Veldhuisen SL, Martin AS, Xiao Y, Galvao M, Giorgi M, Benois M, Espinoza F, Hollyman M, Lloyd A, Hosa H, Schmidt H, Garcia-Galocha JL, van de Vrande S, Chiappetta S, Menzo EL, Aboud CM, Lüthy SG, Orchard P, Rothe S, Prager G, Pournaras DJ, Cohen R, Rosenthal R, Weiner R, Himpens J, Torres A, Higa K, Welbourn R, Berry M, Boza C, Iannelli A, Vithiananthan S, Ramos A, Olbers T, Sepúlveda M, Hazebroek EJ, Dillemans B, Staiger RD, Puhan MA, Peterli R, Bueter M.

Ann Surg. 2019 Oct 4. doi: 10.1097/SLA.0000000000003512. [Epub ahead of print]


Fast versus gradual adaptation of soft daily disposable contact lenses in neophyte wearers.

Wolffsohn JS, Dhirajlal H, Vianya-Estopa M, Nagra M, Madden L, Sweeney LE, Goodyear AS, Kerr LV, Terry L, Sheikh S, Murphy O, Lloyd A, Maldonado-Codina C; members of the British and Irish University and College Contact Lens Educators (BUCCLE) group.

Cont Lens Anterior Eye. 2019 Sep 19. pii: S1367-0484(19)30193-6. doi: 10.1016/j.clae.2019.08.011. [Epub ahead of print]


Identifying patients at risk of futile resuscitation: palliative care indicators in out-of-hospital cardiac arrest.

Cokljat M, Lloyd A, Clarke S, Crawford A, Clegg G.

BMJ Support Palliat Care. 2019 Sep 17. pii: bmjspcare-2019-001828. doi: 10.1136/bmjspcare-2019-001828. [Epub ahead of print]


Clearance of hepatitis C virus is associated with early and potent but narrowly-directed, Envelope-specific antibodies.

Walker MR, Leung P, Eltahla AA, Underwood A, Abayasingam A, Brasher NA, Li H, Wu BR, Maher L, Luciani F, Lloyd AR, Bull RA.

Sci Rep. 2019 Sep 16;9(1):13300. doi: 10.1038/s41598-019-49454-w.


Slumped posture on chest X-ray-association with mortality and length of hospital stay in older hospitalised patients.

Lloyd A, Thomas E, Haboubi H.

Age Ageing. 2019 Jul 1;48(4):588-591. doi: 10.1093/ageing/afz037.


Patient perceptions of their decision to undergo palliative chemotherapy in the Edinburgh Cancer Centre.

Bowden J, Gwyther B, Price A, Swan A, Nussey F, Hacking B, Shearer M, Lloyd A.

J R Coll Physicians Edinb. 2019 Sep;49(3):199-203. doi: 10.4997/JRCPE.2019.306.


Tethered homing gene drives: A new design for spatially restricted population replacement and suppression.

Dhole S, Lloyd AL, Gould F.

Evol Appl. 2019 Jun 17;12(8):1688-1702. doi: 10.1111/eva.12827. eCollection 2019 Sep.


Impact of Ramadan fasting on kidney function and related outcomes in patients with chronic kidney disease: a systematic review protocol.

Bello AK, Kurzawa J, Osman MA, Olah ME, Lloyd A, Wiebe N, Habib S, Qarni U, Shojai S, Pauly RP.

BMJ Open. 2019 Aug 24;9(8):e022710. doi: 10.1136/bmjopen-2018-022710.


Ability of observer and self-report measures to capture shared decision-making in clinical practice in the UK: a mixed-methods study.

Williams D, Edwards A, Wood F, Lloyd A, Brain K, Thomas N, Prichard A, Goodland A, Sweetland H, McGarrigle H, Hill G, Joseph-Williams N.

BMJ Open. 2019 Aug 18;9(8):e029485. doi: 10.1136/bmjopen-2019-029485.


Clinician engagement in research as a path toward the learning health system: A regional survey across the northwestern United States.

Ciemins EL, Mollis BL, Brant JM, Hassell LA, Albritton S, Amoroso P, Lloyd A, Smith JM, Pflugeisen BM, Tuttle KR, Baldwin LM.

Health Serv Manage Res. 2019 Aug 18:951484819858830. doi: 10.1177/0951484819858830. [Epub ahead of print] No abstract available.


Contribution of individual psychological and psychosocial factors to symptom severity and time-to-recovery after naturally-occurring acute infective illness: The Dubbo Infection Outcomes Study (DIOS).

Cvejic E, Li H, Hickie IB, Wakefield D, Lloyd AR, Vollmer-Conna U.

Brain Behav Immun. 2019 Nov;82:76-83. doi: 10.1016/j.bbi.2019.07.034. Epub 2019 Jul 31.


Efficacy of liposomal bupivacaine versus bupivacaine in port site injections on postoperative pain within enhanced recovery after bariatric surgery program: a randomized clinical trial.

Ma P, Lloyd A, McGrath M, Shuchleib Cung A, Akusoba I, Jackson A, Swartz D, Boone K, Higa K.

Surg Obes Relat Dis. 2019 Sep;15(9):1554-1562. doi: 10.1016/j.soard.2019.06.004. Epub 2019 Jun 17.


'Spigelian-type' hernia: a rare laparoscopic trocar site hernia following total laparoscopic hysterectomy.

Leong E, Lloyd A, Pounds R, O'Neill D, Singh K, Yap J.

J Obstet Gynaecol. 2019 Jul 29:1-2. doi: 10.1080/01443615.2019.1626354. [Epub ahead of print] No abstract available.


A descriptive model of shared decision making derived from routine implementation in clinical practice ('Implement-SDM'): Qualitative study.

Joseph-Williams N, Williams D, Wood F, Lloyd A, Brain K, Thomas N, Prichard A, Goodland A, McGarrigle H, Sweetland H, Edwards A.

Patient Educ Couns. 2019 Oct;102(10):1774-1785. doi: 10.1016/j.pec.2019.07.016. Epub 2019 Jul 15.


Reduction of opioid use after implementation of enhanced recovery after bariatric surgery (ERABS).

Ma P, Lloyd A, McGrath M, Moore R, Jackson A, Boone K, Higa K.

Surg Endosc. 2019 Jul 24. doi: 10.1007/s00464-019-07006-3. [Epub ahead of print]


Single-Dose Vaccination with a Hepatotropic Adeno-associated Virus Efficiently Localizes T Cell Immunity in the Liver with the Potential To Confer Rapid Protection against Hepatitis C Virus.

Mekonnen ZA, Grubor-Bauk B, English K, Leung P, Masavuli MG, Shrestha AC, Bertolino P, Bowen DG, Lloyd AR, Gowans EJ, Wijesundara DK.

J Virol. 2019 Sep 12;93(19). pii: e00202-19. doi: 10.1128/JVI.00202-19. Print 2019 Oct 1.


Reversal of Roux en Y gastric bypass: largest single institution experience.

Ma P, Ghiassi S, Lloyd A, Haddad A, Boone K, DeMaria E, Higa K.

Surg Obes Relat Dis. 2019 Aug;15(8):1311-1316. doi: 10.1016/j.soard.2019.05.005. Epub 2019 May 28.


The pro-remyelination properties of microglia in the central nervous system.

Lloyd AF, Miron VE.

Nat Rev Neurol. 2019 Aug;15(8):447-458. doi: 10.1038/s41582-019-0184-2. Review.


Differential Risk of ST-Segment Elevation Myocardial Infarction in Male and Female Smokers.

Palmer J, Lloyd A, Steele L, Fotheringham J, Teare D, Iqbal J, Grech ED.

J Am Coll Cardiol. 2019 Jul 2;73(25):3259-3266. doi: 10.1016/j.jacc.2019.03.525.


Spot and Cumulative Urine Samples Are Suitable Replacements for 24-Hour Urine Collections for Objective Measures of Dietary Exposure in Adults Using Metabolite Biomarkers.

Wilson T, Garcia-Perez I, Posma JM, Lloyd AJ, Chambers ES, Tailliart K, Zubair H, Beckmann M, Mathers JC, Holmes E, Frost G, Draper J.

J Nutr. 2019 Oct 1;149(10):1692-1700. doi: 10.1093/jn/nxz138.


Severe Eosinophilic Meningoencephalitis Secondary to Suspected Neuroangiostrongyliasis with a Good Clinical Outcome.

Chiong F, Lloyd AR, Post JJ.

Case Rep Infect Dis. 2019 May 26;2019:4037196. doi: 10.1155/2019/4037196. eCollection 2019.


A method for detecting hepatitis C envelope specific memory B cells from multiple genotypes using cocktail E2 tetramers.

Wu BR, Eltahla AA, Keoshkerian E, Walker MR, Underwood A, Brasher NA, Agapiou D, Lloyd AR, Bull RA.

J Immunol Methods. 2019 Sep;472:65-74. doi: 10.1016/j.jim.2019.06.016. Epub 2019 Jun 19.


Schwann cell plasticity-roles in tissue homeostasis, regeneration, and disease.

Stierli S, Imperatore V, Lloyd AC.

Glia. 2019 Nov;67(11):2203-2215. doi: 10.1002/glia.23643. Epub 2019 Jun 19.


A cost-effectiveness evaluation of the originator follitropin alpha compared to the biosimilars for assisted reproduction in Germany.

Xue W, Lloyd A, Falla E, Roeder C, Papsch R, Bühler K.

Int J Womens Health. 2019 May 13;11:319-331. doi: 10.2147/IJWH.S193048. eCollection 2019.


Central nervous system regeneration is driven by microglia necroptosis and repopulation.

Lloyd AF, Davies CL, Holloway RK, Labrak Y, Ireland G, Carradori D, Dillenburg A, Borger E, Soong D, Richardson JC, Kuhlmann T, Williams A, Pollard JW, des Rieux A, Priller J, Miron VE.

Nat Neurosci. 2019 Jul;22(7):1046-1052. doi: 10.1038/s41593-019-0418-z. Epub 2019 Jun 10.


Developing a Food Exposure and Urine Sampling Strategy for Dietary Exposure Biomarker Validation in Free-Living Individuals.

Lloyd AJ, Willis ND, Wilson T, Zubair H, Xie L, Chambers E, Garcia-Perez I, Tailliart K, Beckmann M, Mathers JC, Draper J.

Mol Nutr Food Res. 2019 Jun 3:e1900062. doi: 10.1002/mnfr.201900062. [Epub ahead of print]


Predicting pharmacokinetic behaviour of drug release from drug-eluting embolization beads using in vitro elution methods.

Hagan A, Caine M, Press C, Macfarlane WM, Phillips G, Lloyd AW, Czuczman P, Kilpatrick H, Bascal Z, Tang Y, Garcia P, Lewis AL.

Eur J Pharm Sci. 2019 Aug 1;136:104943. doi: 10.1016/j.ejps.2019.05.021. Epub 2019 May 29.


Reducing MSH4 copy number prevents meiotic crossovers between non-homologous chromosomes in Brassica napus.

Gonzalo A, Lucas MO, Charpentier C, Sandmann G, Lloyd A, Jenczewski E.

Nat Commun. 2019 May 29;10(1):2354. doi: 10.1038/s41467-019-10010-9.


Broadly neutralizing antibodies from an individual that naturally cleared multiple hepatitis C virus infections uncover molecular determinants for E2 targeting and vaccine design.

Keck ZY, Pierce BG, Lau P, Lu J, Wang Y, Underwood A, Bull RA, Prentoe J, Velázquez-Moctezuma R, Walker MR, Luciani F, Guest JD, Fauvelle C, Baumert TF, Bukh J, Lloyd AR, Foung SKH.

PLoS Pathog. 2019 May 17;15(5):e1007772. doi: 10.1371/journal.ppat.1007772. eCollection 2019 May.


Twelve-month outcomes of a father-child lifestyle intervention delivered by trained local facilitators in underserved communities: The Healthy Dads Healthy Kids dissemination trial.

Morgan PJ, Collins CE, Lubans DR, Callister R, Lloyd AB, Plotnikoff RC, Burrows TL, Barnes AT, Pollock ER, Fletcher R, Okely AD, Miller A, Handley S, Young MD.

Transl Behav Med. 2019 May 16;9(3):560-569. doi: 10.1093/tbm/ibz031.


Possible mineral contributions to the diet and health of wild chimpanzees in three East African forests.

Reynolds V, Pascual-Garrido A, Lloyd AW, Lyons P, Hobaiter C.

Am J Primatol. 2019 Jul;81(6):e22978. doi: 10.1002/ajp.22978. Epub 2019 May 14.


Duodenal switch in revisional bariatric surgery: conclusions from an expert consensus panel.

Merz AE, Blackstone RB, Gagner M, Torres AJ, Himpens J, Higa KD, Rosenthal RJ, Lloyd A, DeMaria EJ.

Surg Obes Relat Dis. 2019 Jun;15(6):894-899. doi: 10.1016/j.soard.2019.03.009. Epub 2019 Mar 21.


Validity and effectiveness of paediatric early warning systems and track and trigger tools for identifying and reducing clinical deterioration in hospitalised children: a systematic review.

Trubey R, Huang C, Lugg-Widger FV, Hood K, Allen D, Edwards D, Lacy D, Lloyd A, Mann M, Mason B, Oliver A, Roland D, Sefton G, Skone R, Thomas-Jones E, Tume LN, Powell C.

BMJ Open. 2019 May 5;9(5):e022105. doi: 10.1136/bmjopen-2018-022105.


Advanced Data Visualisation in Health Economics and Outcomes Research: Opportunities and Challenges.

Szabo SM, Johnston KM, Lloyd AJ.

Appl Health Econ Health Policy. 2019 Aug;17(4):433-441. doi: 10.1007/s40258-019-00476-5.


Addressing the pitfalls when designing intervention studies to discover and validate biomarkers of habitual dietary intake.

Lloyd AJ, Willis ND, Wilson T, Zubair H, Chambers E, Garcia-Perez I, Xie L, Tailliart K, Beckmann M, Mathers JC, Draper J.

Metabolomics. 2019 May 2;15(5):72. doi: 10.1007/s11306-019-1532-3.


Toward DNA-Based T-Cell Mediated Vaccines to Target HIV-1 and Hepatitis C Virus: Approaches to Elicit Localized Immunity for Protection.

Mekonnen ZA, Grubor-Bauk B, Masavuli MG, Shrestha AC, Ranasinghe C, Bull RA, Lloyd AR, Gowans EJ, Wijesundara DK.

Front Cell Infect Microbiol. 2019 Apr 3;9:91. doi: 10.3389/fcimb.2019.00091. eCollection 2019. Review.


Systemic inflammatory response predicts oncological outcomes in patients undergoing elective surgery for mismatch repair-deficient colorectal cancer.

Climent M, Ryan ÉJ, Stakelum Á, Khaw YL, Creavin B, Lloyd A, Alhassan D, Mohan HM, Kennelly R, Sheahan K, Winter DC.

Int J Colorectal Dis. 2019 Jun;34(6):1069-1078. doi: 10.1007/s00384-019-03274-6. Epub 2019 Apr 16.


Scale-up of hepatitis C treatment in prisons is key to national elimination.

Papaluca T, Hellard ME, Thompson AJV, Lloyd AR.

Med J Aust. 2019 May;210(9):391-393.e1. doi: 10.5694/mja2.50140. Epub 2019 Apr 9. No abstract available.


Outcomes of a nurse-led model of care for hepatitis C assessment and treatment with direct-acting antivirals in the custodial setting.

Overton K, Clegg J, Pekin F, Wood J, McGrath C, Lloyd A, Post JJ.

Int J Drug Policy. 2019 Oct;72:123-128. doi: 10.1016/j.drugpo.2019.02.013. Epub 2019 Apr 6.


Response to Commentary: 'Myalgic Encephalomyelitis, Chronic Fatigue Syndrome, and Chronic Fatigue: Three Distinct Entities Requiring Complete Different Approaches'.

Beilharz JE, Fatt SJ, Cvejic E, Lloyd AR, Vollmer-Conna U.

Curr Rheumatol Rep. 2019 Apr 6;21(6):22. doi: 10.1007/s11926-019-0824-y. Review. No abstract available.


Interventions to Promote Oral Medication Adherence in the Pediatric Chronic Illness Population: A Systematic Review From the Children's Oncology Group.

Coyne KD, Trimble KA, Lloyd A, Petrando L, Pentz J, Van Namen K, Fawcett A, Laing CM.

J Pediatr Oncol Nurs. 2019 May/Jun;36(3):219-235. doi: 10.1177/1043454219835451. Epub 2019 Apr 4.


Peptide Super-Agonist Enhances T-Cell Responses to Melanoma.

Galloway SAE, Dolton G, Attaf M, Wall A, Fuller A, Rius C, Bianchi V, Theaker S, Lloyd A, Caillaud ME, Svane IM, Donia M, Cole DK, Szomolay B, Rizkallah P, Sewell AK.

Front Immunol. 2019 Mar 13;10:319. doi: 10.3389/fimmu.2019.00319. eCollection 2019.


The use of infrared thermal imaging to measure spatial and temporal sweat retention in clothing.

Raccuglia M, Heyde C, Lloyd A, Hodder S, Havenith G.

Int J Biometeorol. 2019 Jul;63(7):885-894. doi: 10.1007/s00484-019-01701-5. Epub 2019 Mar 27.


Statin use and the risk of acute kidney injury in older adults.

Tonelli M, Lloyd AM, Bello AK, James MT, Klarenbach SW, McAlister FA, Manns BJ, Tsuyuki RT, Hemmelgarn BR; Alberta Kidney Disease Network.

BMC Nephrol. 2019 Mar 25;20(1):103. doi: 10.1186/s12882-019-1280-7.


From process to progress-2017 International Conference on Neurofibromatosis 1, Neurofibromatosis 2 and Schwannomatosis.

Ferner RE, Bakker A, Elgersma Y, Evans DGR, Giovannini M, Legius E, Lloyd A, Messiaen LM, Plotkin S, Reilly KM, Schindeler A, Smith MJ, Ullrich NJ, Widemann B, Sherman LS.

Am J Med Genet A. 2019 Jun;179(6):1098-1106. doi: 10.1002/ajmg.a.61112. Epub 2019 Mar 25.


Pest management by genetic addiction.

Gould F, Dhole S, Lloyd AL.

Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):5849-5851. doi: 10.1073/pnas.1901886116. Epub 2019 Mar 15. No abstract available.


Comment on: Subjective thermal strain impairs endurance performance in a temperate environment.

Lloyd A, Havenith G.

Physiol Behav. 2019 May 15;204:275-276. doi: 10.1016/j.physbeh.2019.03.006. Epub 2019 Mar 9. No abstract available.


Genomic characterization of hepatitis C virus transmitted founder variants with deep sequencing.

Abayasingam A, Leung P, Eltahla A, Bull RA, Luciani F, Grebely J, Dore GJ, Applegate T, Page K, Bruneau J, Cox AL, Kim AY, Schinkel J, Shoukry NH, Lauer GM, Maher L, Hellard M, Prins M, Lloyd A, Rodrigo C; InC3 Study Group.

Infect Genet Evol. 2019 Jul;71:36-41. doi: 10.1016/j.meegid.2019.02.032. Epub 2019 Mar 8.


Identification, Review, and Use of Health State Utilities in Cost-Effectiveness Models: An ISPOR Good Practices for Outcomes Research Task Force Report.

Brazier J, Ara R, Azzabi I, Busschbach J, Chevrou-Séverac H, Crawford B, Cruz L, Karnon J, Lloyd A, Paisley S, Pickard AS.

Value Health. 2019 Mar;22(3):267-275. doi: 10.1016/j.jval.2019.01.004. Review.


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