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Items: 21

1.

Protein Kinase C-β Dictates B Cell Fate by Regulating Mitochondrial Remodeling, Metabolic Reprogramming, and Heme Biosynthesis.

Tsui C, Martinez-Martin N, Gaya M, Maldonado P, Llorian M, Legrave NM, Rossi M, MacRae JI, Cameron AJ, Parker PJ, Leitges M, Bruckbauer A, Batista FD.

Immunity. 2018 Jun 19;48(6):1144-1159.e5. doi: 10.1016/j.immuni.2018.04.031. Epub 2018 Jun 5.

2.

IL-7-dependent maintenance of ILC3s is required for normal entry of lymphocytes into lymph nodes.

Yang J, Cornelissen F, Papazian N, Reijmers RM, Llorian M, Cupedo T, Coles M, Seddon B.

J Exp Med. 2018 Apr 2;215(4):1069-1077. doi: 10.1084/jem.20170518. Epub 2018 Feb 22.

3.

The U2AF1S34F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes.

Yip BH, Steeples V, Repapi E, Armstrong RN, Llorian M, Roy S, Shaw J, Dolatshad H, Taylor S, Verma A, Bartenstein M, Vyas P, Cross NC, Malcovati L, Cazzola M, Hellström-Lindberg E, Ogawa S, Smith CW, Pellagatti A, Boultwood J.

J Clin Invest. 2017 Sep 1;127(9):3557. doi: 10.1172/JCI96202. Epub 2017 Sep 1. No abstract available.

4.

Dual RNA Processing Roles of Pat1b via Cytoplasmic Lsm1-7 and Nuclear Lsm2-8 Complexes.

Vindry C, Marnef A, Broomhead H, Twyffels L, Ozgur S, Stoecklin G, Llorian M, Smith CW, Mata J, Weil D, Standart N.

Cell Rep. 2017 Aug 1;20(5):1187-1200. doi: 10.1016/j.celrep.2017.06.091.

5.

The U2AF1S34F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes.

Yip BH, Steeples V, Repapi E, Armstrong RN, Llorian M, Roy S, Shaw J, Dolatshad H, Taylor S, Verma A, Bartenstein M, Vyas P, Cross NC, Malcovati L, Cazzola M, Hellström-Lindberg E, Ogawa S, Smith CW, Pellagatti A, Boultwood J.

J Clin Invest. 2017 Jun 1;127(6):2206-2221. doi: 10.1172/JCI91363. Epub 2017 Apr 24. Erratum in: J Clin Invest. 2017 Sep 1;127(9):3557.

6.

Functional interactions between polypyrimidine tract binding protein and PRI peptide ligand containing proteins.

Coelho MB, Ascher DB, Gooding C, Lang E, Maude H, Turner D, Llorian M, Pires DE, Attig J, Smith CW.

Biochem Soc Trans. 2016 Aug 15;44(4):1058-65. doi: 10.1042/BST20160080. Review.

PMID:
27528752
7.

The alternative splicing program of differentiated smooth muscle cells involves concerted non-productive splicing of post-transcriptional regulators.

Llorian M, Gooding C, Bellora N, Hallegger M, Buckroyd A, Wang X, Rajgor D, Kayikci M, Feltham J, Ule J, Eyras E, Smith CW.

Nucleic Acids Res. 2016 Oct 14;44(18):8933-8950. Epub 2016 Jun 17.

8.

Cryptic splicing events in the iron transporter ABCB7 and other key target genes in SF3B1-mutant myelodysplastic syndromes.

Dolatshad H, Pellagatti A, Liberante FG, Llorian M, Repapi E, Steeples V, Roy S, Scifo L, Armstrong RN, Shaw J, Yip BH, Killick S, Kušec R, Taylor S, Mills KI, Savage KI, Smith CW, Boultwood J.

Leukemia. 2016 Dec;30(12):2322-2331. doi: 10.1038/leu.2016.149. Epub 2016 May 23.

9.

Polypyrimidine tract-binding protein binds to the 5' untranslated region of the mouse mammary tumor virus mRNA and stimulates cap-independent translation initiation.

Cáceres CJ, Contreras N, Angulo J, Vera-Otarola J, Pino-Ajenjo C, Llorian M, Ameur M, Lisboa F, Pino K, Lowy F, Sargueil B, López-Lastra M.

FEBS J. 2016 May;283(10):1880-901. doi: 10.1111/febs.13708. Epub 2016 Apr 5.

10.

Generation of functionally distinct isoforms of PTBP3 by alternative splicing and translation initiation.

Tan LY, Whitfield P, Llorian M, Monzon-Casanova E, Diaz-Munoz MD, Turner M, Smith CW.

Nucleic Acids Res. 2015 Jun 23;43(11):5586-600. doi: 10.1093/nar/gkv429. Epub 2015 May 4.

11.

The organization of RNA contacts by PTB for regulation of FAS splicing.

Mickleburgh I, Kafasla P, Cherny D, Llorian M, Curry S, Jackson RJ, Smith CW.

Nucleic Acids Res. 2014 Jul;42(13):8605-20. doi: 10.1093/nar/gku519. Epub 2014 Jun 23.

12.

A pathway involving HDAC5, cFLIP and caspases regulates expression of the splicing regulator polypyrimidine tract binding protein in the heart.

Ye J, Llorian M, Cardona M, Rongvaux A, Moubarak RS, Comella JX, Bassel-Duby R, Flavell RA, Olson EN, Smith CW, Sanchis D.

J Cell Sci. 2013 Apr 1;126(Pt 7):1682-91. doi: 10.1242/jcs.121384. Epub 2013 Feb 19.

13.

Defining the roles and interactions of PTB.

Kafasla P, Mickleburgh I, Llorian M, Coelho M, Gooding C, Cherny D, Joshi A, Kotik-Kogan O, Curry S, Eperon IC, Jackson RJ, Smith CW.

Biochem Soc Trans. 2012 Aug;40(4):815-20. doi: 10.1042/BST20120044. Review.

14.

Decoding muscle alternative splicing.

Llorian M, Smith CW.

Curr Opin Genet Dev. 2011 Aug;21(4):380-7. doi: 10.1016/j.gde.2011.03.006. Epub 2011 Apr 21. Review.

PMID:
21514141
15.

Position-dependent alternative splicing activity revealed by global profiling of alternative splicing events regulated by PTB.

Llorian M, Schwartz S, Clark TA, Hollander D, Tan LY, Spellman R, Gordon A, Schweitzer AC, de la Grange P, Ast G, Smith CW.

Nat Struct Mol Biol. 2010 Sep;17(9):1114-23. doi: 10.1038/nsmb.1881. Epub 2010 Aug 15.

16.

Alternative splicing: global insights.

Hallegger M, Llorian M, Smith CW.

FEBS J. 2010 Feb;277(4):856-66. doi: 10.1111/j.1742-4658.2009.07521.x. Epub 2010 Jan 15. Review.

17.

Polypyrimidine tract binding protein regulates alternative splicing of an aberrant pseudoexon in NF1.

Raponi M, Buratti E, Llorian M, Stuani C, Smith CW, Baralle D.

FEBS J. 2008 Dec;275(24):6101-8. doi: 10.1111/j.1742-4658.2008.06734.x. Epub 2008 Nov 1.

18.
19.

The PI3K p110delta is required for down-regulation of RAG expression in immature B cells.

Llorian M, Stamataki Z, Hill S, Turner M, Mårtensson IL.

J Immunol. 2007 Feb 15;178(4):1981-5.

20.

Nucleocytoplasmic shuttling of the splicing factor SIPP1.

Llorian M, Beullens M, Lesage B, Nicolaescu E, Beke L, Landuyt W, Ortiz JM, Bollen M.

J Biol Chem. 2005 Nov 18;280(46):38862-9. Epub 2005 Sep 14.

21.

SIPP1, a novel pre-mRNA splicing factor and interactor of protein phosphatase-1.

Llorian M, Beullens M, Andrés I, Ortiz JM, Bollen M.

Biochem J. 2004 Feb 15;378(Pt 1):229-38.

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