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Best matches for Llinás M[au]:

Nutrient sensing modulates malaria parasite virulence. Mancio-Silva L et al. Nature. (2017)

Red Blood Cell Invasion by the Malaria Parasite Is Coordinated by the PfAP2-I Transcription Factor. Santos JM et al. Cell Host Microbe. (2017)

Less Lipid, More Commitment. Llinás M et al. Cell. (2017)

Search results

Items: 1 to 50 of 262

1.

Plasmodium Niemann-Pick type C1-related protein is a druggable target required for parasite membrane homeostasis.

Istvan ES, Das S, Bhatnagar S, Beck JR, Owen E, Llinas M, Ganesan SM, Niles JC, Winzeler E, Vaidya AB, Goldberg DE.

Elife. 2019 Mar 19;8. pii: e40529. doi: 10.7554/eLife.40529.

2.

Successful spinal cord stimulation for severe medication-refractory restless legs syndrome.

De Vloo P, Reddy GD, Rowland N, Sammartino F, Llinas M, Paul D, Murray BJ, Lang AE, Fasano A, Munhoz RP, Kalia SK.

Mov Disord. 2019 Feb 15. doi: 10.1002/mds.27644. [Epub ahead of print] No abstract available.

PMID:
30768799
3.

Identifying the components of acidosis in patients with severe P. falciparum malaria using metabolomics.

Leopold SJ, Ghose A, Allman EL, Kingston HWF, Hossain A, Dutta AK, Plewes K, Chotivanich K, Day NPJ, Tarning J, Winterberg M, White NJ, Llinás M, Dondorp AM.

J Infect Dis. 2018 Dec 19. doi: 10.1093/infdis/jiy727. [Epub ahead of print]

PMID:
30566600
4.

Open-source discovery of chemical leads for next-generation chemoprotective antimalarials.

Antonova-Koch Y, Meister S, Abraham M, Luth MR, Ottilie S, Lukens AK, Sakata-Kato T, Vanaerschot M, Owen E, Jado JC, Maher SP, Calla J, Plouffe D, Zhong Y, Chen K, Chaumeau V, Conway AJ, McNamara CW, Ibanez M, Gagaring K, Serrano FN, Eribez K, Taggard CM, Cheung AL, Lincoln C, Ambachew B, Rouillier M, Siegel D, Nosten F, Kyle DE, Gamo FJ, Zhou Y, Llinás M, Fidock DA, Wirth DF, Burrows J, Campo B, Winzeler EA.

Science. 2018 Dec 7;362(6419). pii: eaat9446. doi: 10.1126/science.aat9446.

PMID:
30523084
5.

Sex-dependent differences in the adverse renal changes induced by an early in life exposure to a high-fat diet.

Moreno JM, Tapia A, Martinez CM, Reverte V, Oltra L, Llinas MT, Salazar FJ.

Am J Physiol Renal Physiol. 2019 Feb 1;316(2):F332-F340. doi: 10.1152/ajprenal.00394.2018. Epub 2018 Dec 5.

PMID:
30516421
6.

Focused ultrasound thalamotomy location determines clinical benefits in patients with essential tremor.

Boutet A, Ranjan M, Zhong J, Germann J, Xu D, Schwartz ML, Lipsman N, Hynynen K, Devenyi GA, Chakravarty M, Hlasny E, Llinas M, Lozano CS, Elias GJB, Chan J, Coblentz A, Fasano A, Kucharczyk W, Hodaie M, Lozano AM.

Brain. 2018 Dec 1;141(12):3405-3414. doi: 10.1093/brain/awy278.

PMID:
30452554
7.

Inducing controlled cell cycle arrest and re-entry during asexual proliferation of Plasmodium falciparum malaria parasites.

van Biljon R, Niemand J, van Wyk R, Clark K, Verlinden B, Abrie C, von Grüning H, Smidt W, Smit A, Reader J, Painter H, Llinás M, Doerig C, Birkholtz LM.

Sci Rep. 2018 Nov 8;8(1):16581. doi: 10.1038/s41598-018-34964-w.

8.

Magnetic resonance-guided focused ultrasound thalamotomy for treatment of essential tremor: A 2-year outcome study.

Meng Y, Solomon B, Boutet A, Llinas M, Scantlebury N, Huang Y, Hynynen K, Hamani C, Fasano A, Lozano AM, Lipsman N, Schwartz ML.

Mov Disord. 2018 Oct;33(10):1647-1650. doi: 10.1002/mds.99. Epub 2018 Oct 4.

PMID:
30288794
9.

Lipopeptisomes: Anticancer peptide-assembled particles for fusolytic oncotherapy.

Aronson MR, Simonson AW, Orchard LM, Llinás M, Medina SH.

Acta Biomater. 2018 Oct 15;80:269-277. doi: 10.1016/j.actbio.2018.09.025. Epub 2018 Sep 19.

PMID:
30240951
10.

NLCs as a potential carrier system for transdermal delivery of forskolin.

Lasoń E, Sikora E, Miastkowska M, Escribano E, Garcia-Celma MJ, Solans C, Llinas M, Ogonowski J.

Acta Biochim Pol. 2018;65(3):437-442. doi: 10.18388/abp.2018_2554. Epub 2018 Sep 15.

11.

Evidence for Regulation of Hemoglobin Metabolism and Intracellular Ionic Flux by the Plasmodium falciparum Chloroquine Resistance Transporter.

Lee AH, Dhingra SK, Lewis IA, Singh MK, Siriwardana A, Dalal S, Rubiano K, Klein MS, Baska KS, Krishna S, Klemba M, Roepe PD, Llinás M, Garcia CRS, Fidock DA.

Sci Rep. 2018 Sep 11;8(1):13578. doi: 10.1038/s41598-018-31715-9.

12.

Glycolysis is important for optimal asexual growth and formation of mature tissue cysts by Toxoplasma gondii.

Shukla A, Olszewski KL, Llinás M, Rommereim LM, Fox BA, Bzik DJ, Xia D, Wastling J, Beiting D, Roos DS, Shanmugam D.

Int J Parasitol. 2018 Oct;48(12):955-968. doi: 10.1016/j.ijpara.2018.05.013. Epub 2018 Aug 31.

PMID:
30176233
13.

A seven-helix protein constitutes stress granules crucial for regulating translation during human-to-mosquito transmission of Plasmodium falciparum.

Bennink S, von Bohl A, Ngwa CJ, Henschel L, Kuehn A, Pilch N, Weißbach T, Rosinski AN, Scheuermayer M, Repnik U, Przyborski JM, Minns AM, Orchard LM, Griffiths G, Lindner SE, Llinás M, Pradel G.

PLoS Pathog. 2018 Aug 22;14(8):e1007249. doi: 10.1371/journal.ppat.1007249. eCollection 2018 Aug.

14.

Genome-wide real-time in vivo transcriptional dynamics during Plasmodium falciparum blood-stage development.

Painter HJ, Chung NC, Sebastian A, Albert I, Storey JD, Llinás M.

Nat Commun. 2018 Jul 9;9(1):2656. doi: 10.1038/s41467-018-04966-3.

15.

Regulation of Sexual Commitment and Gametocytogenesis in Malaria Parasites.

Josling GA, Williamson KC, Llinás M.

Annu Rev Microbiol. 2018 Sep 8;72:501-519. doi: 10.1146/annurev-micro-090817-062712. Epub 2018 Jul 5.

PMID:
29975590
16.

Preparation of a mesoporous silica-based nano-vehicle for dual DOX/CPT pH-triggered delivery.

Llinàs MC, Martínez-Edo G, Cascante A, Porcar I, Borrós S, Sánchez-García D.

Drug Deliv. 2018 Nov;25(1):1137-1146. doi: 10.1080/10717544.2018.1472678.

17.

Magnetic Resonance Imaging-Guided Focused Ultrasound Thalamotomy in Parkinson Tremor: Reoperation After Benefit Decay.

Fasano A, De Vloo P, Llinas M, Hlasny E, Kucharczyk W, Hamani C, Lozano AM.

Mov Disord. 2018 May;33(5):848-849. doi: 10.1002/mds.27348. Epub 2018 Mar 23. No abstract available.

PMID:
29570865
18.

Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics.

Cowell AN, Istvan ES, Lukens AK, Gomez-Lorenzo MG, Vanaerschot M, Sakata-Kato T, Flannery EL, Magistrado P, Owen E, Abraham M, LaMonte G, Painter HJ, Williams RM, Franco V, Linares M, Arriaga I, Bopp S, Corey VC, Gnädig NF, Coburn-Flynn O, Reimer C, Gupta P, Murithi JM, Moura PA, Fuchs O, Sasaki E, Kim SW, Teng CH, Wang LT, Akidil A, Adjalley S, Willis PA, Siegel D, Tanaseichuk O, Zhong Y, Zhou Y, Llinás M, Ottilie S, Gamo FJ, Lee MCS, Goldberg DE, Fidock DA, Wirth DF, Winzeler EA.

Science. 2018 Jan 12;359(6372):191-199. doi: 10.1126/science.aan4472.

19.

Specific Inhibition of the Bifunctional Farnesyl/Geranylgeranyl Diphosphate Synthase in Malaria Parasites via a New Small-Molecule Binding Site.

Gisselberg JE, Herrera Z, Orchard LM, Llinás M, Yeh E.

Cell Chem Biol. 2018 Feb 15;25(2):185-193.e5. doi: 10.1016/j.chembiol.2017.11.010. Epub 2017 Dec 21.

20.

Less Lipid, More Commitment.

Llinás M.

Cell. 2017 Dec 14;171(7):1474-1476. doi: 10.1016/j.cell.2017.11.044.

21.

Nano-emulsions as vehicles for topical delivery of forskolin.

Miastkowska M, Sikora E, Lasoń E, Garcia-Celma MJ, Escribano-Ferrer E, Solans C, Llinas M.

Acta Biochim Pol. 2017;64(4):713-718. doi: 10.18388/abp.2017_2334. Epub 2017 Dec 13.

22.

Simultaneous genome-wide gene expression and transcript isoform profiling in the human malaria parasite.

Turnbull LB, Siwo GH, Button-Simons KA, Tan A, Checkley LA, Painter HJ, Llinás M, Ferdig MT.

PLoS One. 2017 Nov 7;12(11):e0187595. doi: 10.1371/journal.pone.0187595. eCollection 2017.

23.

Transcriptional Profiling Defines Histone Acetylation as a Regulator of Gene Expression during Human-to-Mosquito Transmission of the Malaria Parasite Plasmodium falciparum.

Ngwa CJ, Kiesow MJ, Papst O, Orchard LM, Filarsky M, Rosinski AN, Voss TS, Llinás M, Pradel G.

Front Cell Infect Microbiol. 2017 Jul 24;7:320. doi: 10.3389/fcimb.2017.00320. eCollection 2017.

24.

MRI-guided focused ultrasound thalamotomy in non-ET tremor syndromes.

Fasano A, Llinas M, Munhoz RP, Hlasny E, Kucharczyk W, Lozano AM.

Neurology. 2017 Aug 22;89(8):771-775. doi: 10.1212/WNL.0000000000004268. Epub 2017 Jul 26.

PMID:
28747452
25.

Nutrient sensing modulates malaria parasite virulence.

Mancio-Silva L, Slavic K, Grilo Ruivo MT, Grosso AR, Modrzynska KK, Vera IM, Sales-Dias J, Gomes AR, MacPherson CR, Crozet P, Adamo M, Baena-Gonzalez E, Tewari R, Llinás M, Billker O, Mota MM.

Nature. 2017 Jul 13;547(7662):213-216. doi: 10.1038/nature23009. Epub 2017 Jul 5.

26.

Red Blood Cell Invasion by the Malaria Parasite Is Coordinated by the PfAP2-I Transcription Factor.

Santos JM, Josling G, Ross P, Joshi P, Orchard L, Campbell T, Schieler A, Cristea IM, Llinás M.

Cell Host Microbe. 2017 Jun 14;21(6):731-741.e10. doi: 10.1016/j.chom.2017.05.006.

27.

Capturing in vivo RNA transcriptional dynamics from the malaria parasite Plasmodium falciparum.

Painter HJ, Carrasquilla M, Llinás M.

Genome Res. 2017 Jun;27(6):1074-1086. doi: 10.1101/gr.217356.116. Epub 2017 Apr 17.

28.

Quantitative chromatin proteomics reveals a dynamic histone post-translational modification landscape that defines asexual and sexual Plasmodium falciparum parasites.

Coetzee N, Sidoli S, van Biljon R, Painter H, Llinás M, Garcia BA, Birkholtz LM.

Sci Rep. 2017 Apr 4;7(1):607. doi: 10.1038/s41598-017-00687-7.

29.

Evolution of Fitness Cost-Neutral Mutant PfCRT Conferring P. falciparum 4-Aminoquinoline Drug Resistance Is Accompanied by Altered Parasite Metabolism and Digestive Vacuole Physiology.

Gabryszewski SJ, Dhingra SK, Combrinck JM, Lewis IA, Callaghan PS, Hassett MR, Siriwardana A, Henrich PP, Lee AH, Gnädig NF, Musset L, Llinás M, Egan TJ, Roepe PD, Fidock DA.

PLoS Pathog. 2016 Nov 10;12(11):e1005976. doi: 10.1371/journal.ppat.1005976. eCollection 2016 Nov.

30.

Metabolomic Profiling of the Malaria Box Reveals Antimalarial Target Pathways.

Allman EL, Painter HJ, Samra J, Carrasquilla M, Llinás M.

Antimicrob Agents Chemother. 2016 Oct 21;60(11):6635-6649. doi: 10.1128/AAC.01224-16. Print 2016 Nov.

31.

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.

Van Voorhis WC, Adams JH, Adelfio R, Ahyong V, Akabas MH, Alano P, Alday A, Alemán Resto Y, Alsibaee A, Alzualde A, Andrews KT, Avery SV, Avery VM, Ayong L, Baker M, Baker S, Ben Mamoun C, Bhatia S, Bickle Q, Bounaadja L, Bowling T, Bosch J, Boucher LE, Boyom FF, Brea J, Brennan M, Burton A, Caffrey CR, Camarda G, Carrasquilla M, Carter D, Belen Cassera M, Chih-Chien Cheng K, Chindaudomsate W, Chubb A, Colon BL, Colón-López DD, Corbett Y, Crowther GJ, Cowan N, D'Alessandro S, Le Dang N, Delves M, DeRisi JL, Du AY, Duffy S, Abd El-Salam El-Sayed S, Ferdig MT, Fernández Robledo JA, Fidock DA, Florent I, Fokou PV, Galstian A, Gamo FJ, Gokool S, Gold B, Golub T, Goldgof GM, Guha R, Guiguemde WA, Gural N, Guy RK, Hansen MA, Hanson KK, Hemphill A, Hooft van Huijsduijnen R, Horii T, Horrocks P, Hughes TB, Huston C, Igarashi I, Ingram-Sieber K, Itoe MA, Jadhav A, Naranuntarat Jensen A, Jensen LT, Jiang RH, Kaiser A, Keiser J, Ketas T, Kicka S, Kim S, Kirk K, Kumar VP, Kyle DE, Lafuente MJ, Landfear S, Lee N, Lee S, Lehane AM, Li F, Little D, Liu L, Llinás M, Loza MI, Lubar A, Lucantoni L, Lucet I, Maes L, Mancama D, Mansour NR, March S, McGowan S, Medina Vera I, Meister S, Mercer L, Mestres J, Mfopa AN, Misra RN, Moon S, Moore JP, Morais Rodrigues da Costa F, Müller J, Muriana A, Nakazawa Hewitt S, Nare B, Nathan C, Narraidoo N, Nawaratna S, Ojo KK, Ortiz D, Panic G, Papadatos G, Parapini S, Patra K, Pham N, Prats S, Plouffe DM, Poulsen SA, Pradhan A, Quevedo C, Quinn RJ, Rice CA, Abdo Rizk M, Ruecker A, St Onge R, Salgado Ferreira R, Samra J, Robinett NG, Schlecht U, Schmitt M, Silva Villela F, Silvestrini F, Sinden R, Smith DA, Soldati T, Spitzmüller A, Stamm SM, Sullivan DJ, Sullivan W, Suresh S, Suzuki BM, Suzuki Y, Swamidass SJ, Taramelli D, Tchokouaha LR, Theron A, Thomas D, Tonissen KF, Townson S, Tripathi AK, Trofimov V, Udenze KO, Ullah I, Vallieres C, Vigil E, Vinetz JM, Voong Vinh P, Vu H, Watanabe NA, Weatherby K, White PM, Wilks AF, Winzeler EA, Wojcik E, Wree M, Wu W, Yokoyama N, Zollo PH, Abla N, Blasco B, Burrows J, Laleu B, Leroy D, Spangenberg T, Wells T, Willis PA.

PLoS Pathog. 2016 Jul 28;12(7):e1005763. doi: 10.1371/journal.ppat.1005763. eCollection 2016 Jul.

32.

MRI-guided focused ultrasound thalamotomy in fragile X-associated tremor/ataxia syndrome.

Fasano A, Sammartino F, Llinas M, Lozano AM.

Neurology. 2016 Aug 16;87(7):736-8. doi: 10.1212/WNL.0000000000002982. Epub 2016 Jul 20. No abstract available.

PMID:
27440151
33.

Studies on the formation of polymeric nano-emulsions obtained via low-energy emulsification and their use as templates for drug delivery nanoparticle dispersions.

Calderó G, Montes R, Llinàs M, García-Celma MJ, Porras M, Solans C.

Colloids Surf B Biointerfaces. 2016 Sep 1;145:922-931. doi: 10.1016/j.colsurfb.2016.06.013. Epub 2016 Jun 8.

PMID:
27341306
34.

Characterization of the Plasmodium falciparum and P. berghei glycerol 3-phosphate acyltransferase involved in FASII fatty acid utilization in the malaria parasite apicoplast.

Shears MJ, MacRae JI, Mollard V, Goodman CD, Sturm A, Orchard LM, Llinás M, McConville MJ, Botté CY, McFadden GI.

Cell Microbiol. 2017 Jan;19(1). doi: 10.1111/cmi.12633. Epub 2016 Aug 1.

35.

Proteome-wide analysis reveals widespread lysine acetylation of major protein complexes in the malaria parasite.

Cobbold SA, Santos JM, Ochoa A, Perlman DH, Llinás M.

Sci Rep. 2016 Jan 27;6:19722. doi: 10.1038/srep19722.

36.

Genome-wide transcriptome profiling reveals functional networks involving the Plasmodium falciparum drug resistance transporters PfCRT and PfMDR1.

Adjalley SH, Scanfeld D, Kozlowski E, Llinás M, Fidock DA.

BMC Genomics. 2015 Dec 21;16:1090. doi: 10.1186/s12864-015-2320-8.

37.

Sequestration and metabolism of host cell arginine by the intraerythrocytic malaria parasite Plasmodium falciparum.

Cobbold SA, Llinás M, Kirk K.

Cell Microbiol. 2016 Jun;18(6):820-30. doi: 10.1111/cmi.12552. Epub 2016 Jan 6.

PMID:
26633083
38.

Nitric oxide, prostaglandins and angiotensin II in the regulation of renal medullary blood flow during volume expansion.

Moreno C, Llinás MT, Rodriguez F, Moreno JM, Salazar FJ.

J Physiol Biochem. 2016 Mar;72(1):1-8. doi: 10.1007/s13105-015-0450-8. Epub 2015 Nov 26.

PMID:
26611113
39.

Beyond the E-Value: Stratified Statistics for Protein Domain Prediction.

Ochoa A, Storey JD, Llinás M, Singh M.

PLoS Comput Biol. 2015 Nov 17;11(11):e1004509. doi: 10.1371/journal.pcbi.1004509. eCollection 2015 Nov.

40.

Mutations in the Plasmodium falciparum chloroquine resistance transporter, PfCRT, enlarge the parasite's food vacuole and alter drug sensitivities.

Pulcini S, Staines HM, Lee AH, Shafik SH, Bouyer G, Moore CM, Daley DA, Hoke MJ, Altenhofen LM, Painter HJ, Mu J, Ferguson DJ, Llinás M, Martin RE, Fidock DA, Cooper RA, Krishna S.

Sci Rep. 2015 Sep 30;5:14552. doi: 10.1038/srep14552.

41.

Sexual development in Plasmodium parasites: knowing when it's time to commit.

Josling GA, Llinás M.

Nat Rev Microbiol. 2015 Sep;13(9):573-87. doi: 10.1038/nrmicro3519. Review.

PMID:
26272409
42.

Renal Effects of Cyclooxygenase Inhibition When Nitric Oxide Synthesis Is Reduced and Angiotensin II Levels Are Enhanced.

López R, Llinás MT, Salazar E, Salazar FJ.

J Cardiovasc Pharmacol. 2015 May;65(5):465-72. doi: 10.1097/FJC.0000000000000215.

PMID:
25945864
43.

Genetic investigation of tricarboxylic acid metabolism during the Plasmodium falciparum life cycle.

Ke H, Lewis IA, Morrisey JM, McLean KJ, Ganesan SM, Painter HJ, Mather MW, Jacobs-Lorena M, Llinás M, Vaidya AB.

Cell Rep. 2015 Apr 7;11(1):164-74. doi: 10.1016/j.celrep.2015.03.011. Epub 2015 Apr 2.

44.

PfSR1 controls alternative splicing and steady-state RNA levels in Plasmodium falciparum through preferential recognition of specific RNA motifs.

Eshar S, Altenhofen L, Rabner A, Ross P, Fastman Y, Mandel-Gutfreund Y, Karni R, Llinás M, Dzikowski R.

Mol Microbiol. 2015 Jun;96(6):1283-97. doi: 10.1111/mmi.13007. Epub 2015 Apr 16.

45.

Transdermal delivery of forskolin from emulsions differing in droplet size.

Sikora E, Llinas M, Garcia-Celma MJ, Escribano E, Solans C.

Colloids Surf B Biointerfaces. 2015 Feb 1;126:541-5. doi: 10.1016/j.colsurfb.2015.01.008. Epub 2015 Jan 9.

PMID:
25620442
46.

Design and in vitro evaluation of biocompatible dexamethasone-loaded nanoparticle dispersions, obtained from nano-emulsions, for inhalatory therapy.

Fornaguera C, Llinàs M, Solans C, Calderó G.

Colloids Surf B Biointerfaces. 2015 Jan 1;125:58-64. doi: 10.1016/j.colsurfb.2014.11.006. Epub 2014 Nov 15.

PMID:
25437064
47.

Supergenomic network compression and the discovery of EXP1 as a glutathione transferase inhibited by artesunate.

Lisewski AM, Quiros JP, Ng CL, Adikesavan AK, Miura K, Putluri N, Eastman RT, Scanfeld D, Regenbogen SJ, Altenhofen L, Llinás M, Sreekumar A, Long C, Fidock DA, Lichtarge O.

Cell. 2014 Aug 14;158(4):916-928. doi: 10.1016/j.cell.2014.07.011.

48.

A Plasmodium falciparum histone deacetylase regulates antigenic variation and gametocyte conversion.

Coleman BI, Skillman KM, Jiang RHY, Childs LM, Altenhofen LM, Ganter M, Leung Y, Goldowitz I, Kafsack BFC, Marti M, Llinás M, Buckee CO, Duraisingh MT.

Cell Host Microbe. 2014 Aug 13;16(2):177-186. doi: 10.1016/j.chom.2014.06.014.

49.

The Cryptosporidium parvum ApiAP2 gene family: insights into the evolution of apicomplexan AP2 regulatory systems.

Oberstaller J, Pumpalova Y, Schieler A, Llinás M, Kissinger JC.

Nucleic Acids Res. 2014 Jul;42(13):8271-84. doi: 10.1093/nar/gku500. Epub 2014 Jun 23.

50.

Sex-dependent hypertension and renal changes in aged rats with altered renal development.

Saez F, Reverte V, Paliege A, Moreno JM, Llinás MT, Bachmann S, Salazar FJ.

Am J Physiol Renal Physiol. 2014 Aug 15;307(4):F461-70. doi: 10.1152/ajprenal.00198.2014. Epub 2014 Jun 18.

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