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Items: 27

1.

Massive integrative gene set analysis enables functional characterization of breast cancer subtypes.

Rodriguez JC, Merino GA, Llera AS, Fernández EA.

J Biomed Inform. 2019 May;93:103157. doi: 10.1016/j.jbi.2019.103157. Epub 2019 Mar 27.

PMID:
30928514
2.

Personalizing Precision Oncology Clinical Trials in Latin America: An Expert Panel on Challenges and Opportunities.

Arai RJ, Guindalini RSC, Llera AS, O'Connor JM, Muller B, Lema M, Freitas HC, Soria T, Delgado L, Landaverde D, Montenegro P, Riechelmann RP.

Oncologist. 2019 Mar 25. pii: theoncologist.2018-0318. doi: 10.1634/theoncologist.2018-0318. [Epub ahead of print]

PMID:
30910864
3.

TarSeqQC: Quality control on targeted sequencing experiments in R.

Merino GA, Murua YA, Fresno C, Sendoya JM, Golubicki M, Iseas S, Coraglio M, Podhajcer OL, Llera AS, Fernández EA.

Hum Mutat. 2017 May;38(5):494-502. doi: 10.1002/humu.23204. Epub 2017 Mar 21.

PMID:
28236343
4.

A novel non-parametric method for uncertainty evaluation of correlation-based molecular signatures: its application on PAM50 algorithm.

Fresno C, González GA, Merino GA, Flesia AG, Podhajcer OL, Llera AS, Fernández EA.

Bioinformatics. 2017 Mar 1;33(5):693-700. doi: 10.1093/bioinformatics/btw704.

PMID:
28062443
5.

Predictive Outcomes for HER2-enriched Cancer Using Growth and Metastasis Signatures Driven By SPARC.

Güttlein LN, Benedetti LG, Fresno C, Spallanzani RG, Mansilla SF, Rotondaro C, Raffo Iraolagoitia XL, Salvatierra E, Bravo AI, Fernández EA, Gottifredi V, Zwirner NW, Llera AS, Podhajcer OL.

Mol Cancer Res. 2017 Mar;15(3):304-316. doi: 10.1158/1541-7786.MCR-16-0243-T. Epub 2016 Dec 28.

6.

Improving information retrieval in functional analysis.

Rodriguez JC, González GA, Fresno C, Llera AS, Fernández EA.

Comput Biol Med. 2016 Dec 1;79:10-20. doi: 10.1016/j.compbiomed.2016.09.017. Epub 2016 Sep 24.

PMID:
27723507
7.

The multi-reference contrast method: facilitating set enrichment analysis.

Fresno C, Llera AS, Girotti MR, Valacco MP, López JA, Podhajcer OL, Balzarini MG, Prada F, Fernández EA.

Comput Biol Med. 2012 Feb;42(2):188-94. doi: 10.1016/j.compbiomed.2011.11.007. Epub 2012 Jan 9.

PMID:
22226646
8.

SPARC promotes cathepsin B-mediated melanoma invasiveness through a collagen I/α2β1 integrin axis.

Girotti MR, Fernández M, López JA, Camafeita E, Fernández EA, Albar JP, Benedetti LG, Valacco MP, Brekken RA, Podhajcer OL, Llera AS.

J Invest Dermatol. 2011 Dec;131(12):2438-47. doi: 10.1038/jid.2011.239. Epub 2011 Aug 18.

9.

Matricellular proteins and inflammatory cells: a task force to promote or defeat cancer?

Llera AS, Girotti MR, Benedetti LG, Podhajcer OL.

Cytokine Growth Factor Rev. 2010 Feb;21(1):67-76. doi: 10.1016/j.cytogfr.2009.11.010. Epub 2009 Dec 16. Review.

PMID:
20006533
10.

Identification of novel Mycobacterium bovis antigens by dissection of crude protein fractions.

Meikle V, Alito A, Llera AS, Gioffré A, Peralta A, Buddle BM, Cataldi A.

Clin Vaccine Immunol. 2009 Sep;16(9):1352-9. doi: 10.1128/CVI.00211-09. Epub 2009 Jul 29.

11.

Improving 2D-DIGE protein expression analysis by two-stage linear mixed models: assessing experimental effects in a melanoma cell study.

Fernández EA, Girotti MR, López del Olmo JA, Llera AS, Podhajcer OL, Cantet RJ, Balzarini M.

Bioinformatics. 2008 Dec 1;24(23):2706-12. doi: 10.1093/bioinformatics/btn508. Epub 2008 Sep 25.

PMID:
18818217
12.

The role of the matricellular protein SPARC in the dynamic interaction between the tumor and the host.

Podhajcer OL, Benedetti LG, Girotti MR, Prada F, Salvatierra E, Llera AS.

Cancer Metastasis Rev. 2008 Dec;27(4):691-705. doi: 10.1007/s10555-008-9146-7. Review.

PMID:
18542844
13.

The role of the matricellular protein SPARC in the dynamic interaction between the tumor and the host.

Podhajcer OL, Benedetti L, Girotti MR, Prada F, Salvatierra E, Llera AS.

Cancer Metastasis Rev. 2008 Sep;27(3):523-37. doi: 10.1007/s10555-008-9135-x. Review.

PMID:
18459035
14.

ATP-dependent modulation and autophosphorylation of rapeseed 2-Cys peroxiredoxin.

Aran M, Caporaletti D, Senn AM, Tellez de Iñon MT, Girotti MR, Llera AS, Wolosiuk RA.

FEBS J. 2008 Apr;275(7):1450-63. doi: 10.1111/j.1742-4658.2008.06299.x. Epub 2008 Feb 14.

15.

SPARC modulates the proliferation of stromal but not melanoma cells unless endogenous SPARC expression is downregulated.

Haber CL, Gottifredi V, Llera AS, Salvatierra E, Prada F, Alonso L, Sage EH, Podhajcer OL.

Int J Cancer. 2008 Apr 1;122(7):1465-75. Erratum in: Int J Cancer. 2008 Jul 1;123(1):245. Helene, Sage E [corrected to Sage, E Helene].

16.

Proteomic analysis identified N-cadherin, clusterin, and HSP27 as mediators of SPARC (secreted protein, acidic and rich in cysteines) activity in melanoma cells.

Sosa MS, Girotti MR, Salvatierra E, Prada F, de Olmo JA, Gallango SJ, Albar JP, Podhajcer OL, Llera AS.

Proteomics. 2007 Nov;7(22):4123-34.

PMID:
17994631
17.

Cloning, expression and interaction of human T-cell receptors with the bacterial superantigen SSA.

De Marzí MC, Fernández MM, Sundberg EJ, Molinero L, Zwirner NW, Llera AS, Mariuzza RA, Malchiodi EL.

Eur J Biochem. 2004 Oct;271(20):4075-83.

18.

Functional analysis of the TCR binding domain of toxic shock syndrome toxin-1 predicts further diversity in MHC class II/superantigen/TCR ternary complexes.

McCormick JK, Tripp TJ, Llera AS, Sundberg EJ, Dinges MM, Mariuzza RA, Schlievert PM.

J Immunol. 2003 Aug 1;171(3):1385-92.

19.

Structures of two streptococcal superantigens bound to TCR beta chains reveal diversity in the architecture of T cell signaling complexes.

Sundberg EJ, Li H, Llera AS, McCormick JK, Tormo J, Schlievert PM, Karjalainen K, Mariuzza RA.

Structure. 2002 May;10(5):687-99.

20.

Crystal structure of imaginal disc growth factor-2. A member of a new family of growth-promoting glycoproteins from Drosophila melanogaster.

Varela PF, Llera AS, Mariuzza RA, Tormo J.

J Biol Chem. 2002 Apr 12;277(15):13229-36. Epub 2002 Jan 30.

21.

Crystal structure of the C-type lectin-like domain from the human hematopoietic cell receptor CD69.

Llera AS, Viedma F, Sánchez-Madrid F, Tormo J.

J Biol Chem. 2001 Mar 9;276(10):7312-9. Epub 2000 Oct 17.

22.

Lack of significant differences in association rates and affinities of antibodies from short-term and long-term responses to hen egg lysozyme.

Goldbaum FA, Cauerhff A, Velikovsky CA, Llera AS, Riottot MM, Poljak RJ.

J Immunol. 1999 May 15;162(10):6040-5.

23.

Structure of the Vdelta domain of a human gammadelta T-cell antigen receptor.

Li H, Lebedeva MI, Llera AS, Fields BA, Brenner MB, Mariuzza RA.

Nature. 1998 Jan 29;391(6666):502-6.

PMID:
9461220
24.

A case of allergy to human insulin associated with high IgG/IgE ratio for specific antibodies.

Frechtel G, Cardoso AI, Llera AS, Poskus E, Alonso A, Ruiz M.

J Investig Allergol Clin Immunol. 1994 Nov-Dec;4(6):320-3.

PMID:
7735521
25.

Solid versus liquid phase assays in detection of insulin antibodies. Influence of iodination site on labelled insulin binding.

Stumpo RR, Llera AS, Cardoso AI, Poskus E.

J Immunol Methods. 1994 Mar 10;169(2):241-9.

PMID:
8133083
26.

Heterologous humoral immune response in patients treated with human growth hormone from different sources.

Cardoso AI, Llera AS, Iacono RF, Domené HM, Martínez AS, Heinrich JJ, Peña C, Poskus E.

Acta Endocrinol (Copenh). 1993 Jul;129(1):20-5.

PMID:
8351954
27.

Detection of autoantibodies against hGH in sera of idiopathic hypopituitary children.

Llera AS, Cardoso AI, Stumpo RR, Martinez AS, Heinrich JJ, Poskus E.

Clin Immunol Immunopathol. 1993 Feb;66(2):114-9.

PMID:
8453783

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