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Items: 23

1.

The HMGB1/RAGE inflammatory pathway promotes pancreatic tumor growth by regulating mitochondrial bioenergetics.

Kang R, Tang D, Schapiro NE, Loux T, Livesey KM, Billiar TR, Wang H, Van Houten B, Lotze MT, Zeh HJ.

Oncogene. 2014 Jan 30;33(5):567-77. doi: 10.1038/onc.2012.631. Epub 2013 Jan 14.

2.

Inhibiting autophagy potentiates the anticancer activity of IFN1@/IFNα in chronic myeloid leukemia cells.

Zhu S, Cao L, Yu Y, Yang L, Yang M, Liu K, Huang J, Kang R, Livesey KM, Tang D.

Autophagy. 2013 Mar;9(3):317-27. doi: 10.4161/auto.22923. Epub 2012 Dec 14.

3.

Breast cancer: never too young for a functional assessment?

Van Londen GJ, Livesey KM, Lembersky BC.

Oncology (Williston Park). 2012 Sep;26(9):811-2. No abstract available.

4.

Direct molecular interactions between HMGB1 and TP53 in colorectal cancer.

Livesey KM, Kang R, Zeh HJ 3rd, Lotze MT, Tang D.

Autophagy. 2012 May 1;8(5):846-8. doi: 10.4161/auto.19891. Epub 2012 May 1.

5.

The expression of the receptor for advanced glycation endproducts (RAGE) is permissive for early pancreatic neoplasia.

Kang R, Loux T, Tang D, Schapiro NE, Vernon P, Livesey KM, Krasinskas A, Lotze MT, Zeh HJ 3rd.

Proc Natl Acad Sci U S A. 2012 May 1;109(18):7031-6. doi: 10.1073/pnas.1113865109. Epub 2012 Apr 16.

6.

HMGB1 is a therapeutic target for leukemia.

Yu Y, Xie M, Kang R, Livesey KM, Cao L, Tang D.

Am J Blood Res. 2012;2(1):36-43. Epub 2012 Jan 1.

7.

p53/HMGB1 complexes regulate autophagy and apoptosis.

Livesey KM, Kang R, Vernon P, Buchser W, Loughran P, Watkins SC, Zhang L, Manfredi JJ, Zeh HJ 3rd, Li L, Lotze MT, Tang D.

Cancer Res. 2012 Apr 15;72(8):1996-2005. doi: 10.1158/0008-5472.CAN-11-2291. Epub 2012 Feb 16.

8.

Metabolic regulation by HMGB1-mediated autophagy and mitophagy.

Kang R, Livesey KM, Zeh HJ 3rd, Lotze MT, Tang D.

Autophagy. 2011 Oct;7(10):1256-8. doi: 10.4161/auto.7.10.16753. Epub 2011 Oct 1.

PMID:
21691146
9.

High-mobility group box 1 is essential for mitochondrial quality control.

Tang D, Kang R, Livesey KM, Kroemer G, Billiar TR, Van Houten B, Zeh HJ 3rd, Lotze MT.

Cell Metab. 2011 Jun 8;13(6):701-11. doi: 10.1016/j.cmet.2011.04.008.

10.

A critical role for UVRAG in apoptosis.

Yin X, Cao L, Peng Y, Tan Y, Xie M, Kang R, Livesey KM, Tang D.

Autophagy. 2011 Oct;7(10):1242-4. doi: 10.4161/auto.7.10.16507. Epub 2011 Oct 1.

11.

UV irradiation resistance-associated gene suppresses apoptosis by interfering with BAX activation.

Yin X, Cao L, Kang R, Yang M, Wang Z, Peng Y, Tan Y, Liu L, Xie M, Zhao Y, Livesey KM, Tang D.

EMBO Rep. 2011 Jul 1;12(7):727-34. doi: 10.1038/embor.2011.79.

12.

HMGB1 as an autophagy sensor in oxidative stress.

Kang R, Livesey KM, Zeh HJ 3rd, Lotze MT, Tang D.

Autophagy. 2011 Aug;7(8):904-6. Epub 2011 Aug 1.

PMID:
21487246
13.

High mobility group box 1 (HMGB1) activates an autophagic response to oxidative stress.

Tang D, Kang R, Livesey KM, Zeh HJ 3rd, Lotze MT.

Antioxid Redox Signal. 2011 Oct 15;15(8):2185-95. doi: 10.1089/ars.2010.3666. Epub 2011 Jun 6.

14.

Autophagy regulates myeloid cell differentiation by p62/SQSTM1-mediated degradation of PML-RARα oncoprotein.

Wang Z, Cao L, Kang R, Yang M, Liu L, Zhao Y, Yu Y, Xie M, Yin X, Livesey KM, Tang D.

Autophagy. 2011 Apr;7(4):401-11. Epub 2011 Apr 1.

15.

The Receptor for Advanced Glycation End-products (RAGE) protects pancreatic tumor cells against oxidative injury.

Kang R, Tang D, Livesey KM, Schapiro NE, Lotze MT, Zeh HJ 3rd.

Antioxid Redox Signal. 2011 Oct 15;15(8):2175-84. doi: 10.1089/ars.2010.3378. Epub 2011 Apr 21.

16.

DAMP-mediated autophagy contributes to drug resistance.

Liu L, Yang M, Kang R, Wang Z, Zhao Y, Yu Y, Xie M, Yin X, Livesey KM, Loze MT, Tang D, Cao L.

Autophagy. 2011 Jan;7(1):112-4. Epub 2011 Jan 1.

17.

HMGB1: a novel Beclin 1-binding protein active in autophagy.

Kang R, Livesey KM, Zeh HJ, Loze MT, Tang D.

Autophagy. 2010 Nov;6(8):1209-11. Epub 2010 Nov 16.

PMID:
20935509
18.

HMGB1-induced autophagy promotes chemotherapy resistance in leukemia cells.

Liu L, Yang M, Kang R, Wang Z, Zhao Y, Yu Y, Xie M, Yin X, Livesey KM, Lotze MT, Tang D, Cao L.

Leukemia. 2011 Jan;25(1):23-31. doi: 10.1038/leu.2010.225. Epub 2010 Oct 7.

PMID:
20927132
19.

Endogenous HMGB1 regulates autophagy.

Tang D, Kang R, Livesey KM, Cheh CW, Farkas A, Loughran P, Hoppe G, Bianchi ME, Tracey KJ, Zeh HJ 3rd, Lotze MT.

J Cell Biol. 2010 Sep 6;190(5):881-92. doi: 10.1083/jcb.200911078.

20.

HMGB1 release and redox regulates autophagy and apoptosis in cancer cells.

Tang D, Kang R, Cheh CW, Livesey KM, Liang X, Schapiro NE, Benschop R, Sparvero LJ, Amoscato AA, Tracey KJ, Zeh HJ, Lotze MT.

Oncogene. 2010 Sep 23;29(38):5299-310. doi: 10.1038/onc.2010.261. Epub 2010 Jul 12.

21.

Autophagy inhibition in combination cancer treatment.

Livesey KM, Tang D, Zeh HJ, Lotze MT.

Curr Opin Investig Drugs. 2009 Dec;10(12):1269-79. Review.

PMID:
19943199
22.

The receptor for advanced glycation end products (RAGE) sustains autophagy and limits apoptosis, promoting pancreatic tumor cell survival.

Kang R, Tang D, Schapiro NE, Livesey KM, Farkas A, Loughran P, Bierhaus A, Lotze MT, Zeh HJ.

Cell Death Differ. 2010 Apr;17(4):666-76. doi: 10.1038/cdd.2009.149. Epub 2009 Oct 16.

23.

Not just nuclear proteins: 'novel' autophagy cancer treatment targets - p53 and HMGB1.

Livesey KM, Tang D, Zeh HJ, Lotze MT.

Curr Opin Investig Drugs. 2008 Dec;9(12):1259-63. No abstract available.

PMID:
19037832

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