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Items: 6

1.

Lysosomal P-gp-MDR1 Confers Drug Resistance of Brentuximab Vedotin and Its Cytotoxic Payload Monomethyl Auristatin E in Tumor Cells.

Liu-Kreyche P, Shen H, Marino AM, Iyer RA, Humphreys WG, Lai Y.

Front Pharmacol. 2019 Jul 17;10:749. doi: 10.3389/fphar.2019.00749. eCollection 2019.

2.

A convenient strategy to overcome interference in LC-MS/MS analysis: Application in a microdose absolute bioavailability study.

Yuan L, Huang C, Liu-Kreyche P, Voronin K, Fancher RM, Allentoff A, Zheng N, Iyer R, Zhu L, Pillutla R, Ji QC.

J Pharm Biomed Anal. 2019 Feb 20;165:198-206. doi: 10.1016/j.jpba.2018.12.014. Epub 2018 Dec 10.

PMID:
30553110
3.

In vitro and in vivo metabolism and pharmacokinetics of BMS-562086, a potent and orally bioavailable corticotropin-releasing factor-1 receptor antagonist.

Zhou L, Dockens RC, Liu-Kreyche P, Grossman SJ, Iyer RA.

Drug Metab Dispos. 2012 Jun;40(6):1093-103. doi: 10.1124/dmd.111.043596. Epub 2012 Mar 1.

PMID:
22381334
4.

In vitro assessment of cytochrome P450 inhibition and induction potential of tanespimycin and its major metabolite, 17-amino-17-demethoxygeldanamycin.

Gan J, Liu-Kreyche P, Humphreys WG.

Cancer Chemother Pharmacol. 2012 Jan;69(1):51-6. doi: 10.1007/s00280-011-1672-2. Epub 2011 May 19.

PMID:
21594721
5.

Metabolism of [2-14C]p-hydroxyphenyl acetic acid in rat, monkey and human hepatocytes and in bile-duct cannulated rats.

Zhou L, Liu-Kreyche P, Iyer RA.

Xenobiotica. 2011 Apr;41(4):312-9. doi: 10.3109/00498254.2010.540681. Epub 2010 Dec 14.

PMID:
21143006
6.

Disposition of [1'-(14)C]stavudine after oral administration to humans.

Zhou L, Kaul S, Liu-Kreyche P, Tran SB, Espina RR, Warrack BM, Roongta VA, Iyer RA.

Drug Metab Dispos. 2010 Apr;38(4):655-66. doi: 10.1124/dmd.109.030239. Epub 2010 Jan 6.

PMID:
20053818

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