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In-Hospital Cost Comparison of Triple-Rule-Out Computed Tomography Angiography Versus Standard of Care in Patients With Acute Chest Pain.

Takx RAP, Wichmann JL, Otani K, De Cecco CN, Tesche C, Baumann S, Mastrodicasa D, Litwin SE, Bayer RR II,, Nance JW, Suranyi P, Jacobs BE, Duguay TM, Vogl TJ, Carr CM, Schoepf UJ.

J Thorac Imaging. 2020 Feb 6. doi: 10.1097/RTI.0000000000000474. [Epub ahead of print]


The Emerging Epidemic of Nonalcoholic Fatty Liver Disease and Cardiovascular Risk: True, True, and Related?

Morningstar JE, Syn WK, Litwin SE.

Dig Dis Sci. 2020 Feb 5. doi: 10.1007/s10620-020-06113-9. [Epub ahead of print] No abstract available.


The Parent Perspective on Return Visits to the Pediatric Emergency Department: A Missing Piece of the Puzzle.

Litwin SP, Diallo M, Ostrow O.

Pediatr Emerg Care. 2020 Feb 1. doi: 10.1097/PEC.0000000000002031. [Epub ahead of print]


Linsitinib (OSI-906) for the Treatment of Adult and Pediatric Wild-Type Gastrointestinal Stromal Tumors, a SARC Phase II Study.

von Mehren M, George S, Heinrich MC, Schuetze SM, Yap JT, Yu JQ, Abbott A, Litwin S, Crowley J, Belinsky M, Janeway KA, Hornick JL, Flieder DB, Chugh R, Rink L, Van den Abbeele AD.

Clin Cancer Res. 2019 Dec 2. doi: 10.1158/1078-0432.CCR-19-1069. [Epub ahead of print]


Exercise effects on arterial stiffness and heart health in children with excess weight: The SMART RCT.

Davis CL, Litwin SE, Pollock NK, Waller JL, Zhu H, Dong Y, Kapuku G, Bhagatwala J, Harris RA, Looney J, Williams CF, Armento A, Schmidt MD, Bassali R.

Int J Obes (Lond). 2019 Nov 21. doi: 10.1038/s41366-019-0482-1. [Epub ahead of print]


Effects of Interatrial Shunt on Pulmonary Vascular Function in Heart Failure With Preserved Ejection Fraction.

Obokata M, Reddy YNV, Shah SJ, Kaye DM, Gustafsson F, Hasenfuβ G, Hoendermis E, Litwin SE, Komtebedde J, Lam C, Burkhoff D, Borlaug BA.

J Am Coll Cardiol. 2019 Nov 26;74(21):2539-2550. doi: 10.1016/j.jacc.2019.08.1062.


Assessment of Predictors of Left Atrial Volume Response to a Transcatheter InterAtrial Shunt Device (from the REDUCE LAP-HF Trial).

Hanff TC, Kaye DM, Hayward CS, Post MC, Malek F, Hasenfuβ G, Gustafsson F, Burkhoff D, Shah SJ, Litwin SE, Kahwash R, Hummel SL, Borlaug BA, Solomon SD, Lam CSP, Komtebedde J, Silvestry FE; REDUCE LAP-HF study investigators, and research staff.

Am J Cardiol. 2019 Dec 15;124(12):1912-1917. doi: 10.1016/j.amjcard.2019.09.019. Epub 2019 Sep 26.


Echocardiographic Assessment of Pericardial Effusion Size: Time for a Quantitative Approach.

DeMaria DM, Waring AA, Gregg DE, Litwin SE.

J Am Soc Echocardiogr. 2019 Dec;32(12):1615-1617.e1. doi: 10.1016/j.echo.2019.08.019. Epub 2019 Oct 19. No abstract available.


Discordances between predicted and actual risk in obese patients with suspected cardiac ischaemia.

Litwin SE, Coles A, Hill CL, Alhanti B, Pagidipati N, Lee KL, Pellikka PA, Mark DB, Udelson JE, Cooper L, Tardif JC, Hoffmann U, Douglas PS; PROMISE investigators.

Heart. 2020 Feb;106(4):273-279. doi: 10.1136/heartjnl-2018-314503. Epub 2019 Oct 10.


Gender differences in the diagnostic performance of machine learning coronary CT angiography-derived fractional flow reserve -results from the MACHINE registry.

Baumann S, Renker M, Schoepf UJ, De Cecco CN, Coenen A, De Geer J, Kruk M, Kim YH, Albrecht MH, Duguay TM, Jacobs BE, Bayer RR, Litwin SE, Weiss C, Akin I, Borggrefe M, Yang DH, Kepka C, Persson A, Nieman K, Tesche C.

Eur J Radiol. 2019 Oct;119:108657. doi: 10.1016/j.ejrad.2019.108657. Epub 2019 Sep 7.


Influence of Coronary Calcium on Diagnostic Performance of Machine Learning CT-FFR: Results From MACHINE Registry.

Tesche C, Otani K, De Cecco CN, Coenen A, De Geer J, Kruk M, Kim YH, Albrecht MH, Baumann S, Renker M, Bayer RR, Duguay TM, Litwin SE, Varga-Szemes A, Steinberg DH, Yang DH, Kepka C, Persson A, Nieman K, Schoepf UJ.

JACC Cardiovasc Imaging. 2019 Aug 14. pii: S1936-878X(19)30635-7. doi: 10.1016/j.jcmg.2019.06.027. [Epub ahead of print]


Relationship Between Pregnancy Complications and Subsequent Coronary Artery Disease Assessed by Coronary Computed Tomographic Angiography in Black Women.

Wichmann JL, Takx RAP, Nunez JH, Vliegenthart R, Otani K, Litwin SE, Morris PB, De Cecco CN, Rosenberg RD, Bayer RR 2nd, Baumann S, Renker M, Vogl TJ, Wenger NK, Schoepf UJ.

Circ Cardiovasc Imaging. 2019 Jul;12(7):e008754. doi: 10.1161/CIRCIMAGING.118.008754. Epub 2019 Jul 15.


Should We Test for Diastolic Dysfunction? How and How Often?

Litwin SE, Zile MR.

JACC Cardiovasc Imaging. 2020 Jan;13(1 Pt 2):297-309. doi: 10.1016/j.jcmg.2019.02.029. Epub 2019 Jun 12. Review.


Cardiac Computed Tomography for Atrial Fibrillation Patients Undergoing Ablation: Implications for the Prediction of Early Recurrence.

Ebersberger U, Bernard ML, Schoepf UJ, Wince WB, Litwin SE, Wang Y, Blanke P, Makowski MR, McQuiston AD, Silverman JR, Gray JC, Tesche C, Duguay TM, Schmidt M, Wharton JM, Bayer RR 2nd.

J Thorac Imaging. 2019 May 27. doi: 10.1097/RTI.0000000000000425. [Epub ahead of print]


Correction: Simultaneous Expression of Furin and Vascular Endothelial Growth Factor in Human Oral Tongue Squamous Cell Carcinoma Progression.

de Cicco RL, Watson JC, Bassi DE, Litwin S, Klein-Szanto AJ.

Clin Cancer Res. 2019 Apr 15;25(8):2673. doi: 10.1158/1078-0432.CCR-19-0490. No abstract available.


Effects of obesity on noninvasive test results in patients with suspected cardiac ischemia: Insights from the PROMISE trial.

Litwin SE, Coles A, Pagidipati N, Lee KL, Pellikka PA, Mark DB, Udelson JE, Hoffmann U, Douglas PS; PROMISE Investigators.

J Cardiovasc Comput Tomogr. 2019 Jul - Aug;13(4):211-218. doi: 10.1016/j.jcct.2019.03.010. Epub 2019 Mar 27.


Targeted blockade of HSP90 impairs DNA-damage response proteins and increases the sensitivity of ovarian carcinoma cells to PARP inhibition.

Gabbasov R, Benrubi ID, O'Brien SW, Krais JJ, Johnson N, Litwin S, Connolly DC.

Cancer Biol Ther. 2019;20(7):1035-1045. doi: 10.1080/15384047.2019.1595279. Epub 2019 Mar 30.


Nutrition, Obesity, and Cachexia in Patients With Heart Failure: A Consensus Statement from the Heart Failure Society of America Scientific Statements Committee.

Vest AR, Chan M, Deswal A, Givertz MM, Lekavich C, Lennie T, Litwin SE, Parsly L, Rodgers JE, Rich MW, Schulze PC, Slader A, Desai A.

J Card Fail. 2019 May;25(5):380-400. doi: 10.1016/j.cardfail.2019.03.007. Epub 2019 Mar 13.


Study on the obtaining of Tityus trivittatus venom in Argentina.

de Roodt AR, Lanari LC, Laskowicz RD, Costa de Oliveira V, Litwin S, Calderon L, Damin CF, Dokmetjian JC, Dolab JA, Lago NR, Lértora E.

Toxicon. 2019 Mar 1;159:5-13. doi: 10.1016/j.toxicon.2018.12.004. Epub 2019 Jan 3.


Sex differences in management and outcomes of patients with stable symptoms suggestive of coronary artery disease: Insights from the PROMISE trial.

Pagidipati NJ, Coles A, Hemal K, Lee KL, Dolor RJ, Pellikka PA, Mark DB, Patel MR, Litwin SE, Daubert MA, Shah SH, Hoffmann U, Douglas PS; PROMISE Investigators.

Am Heart J. 2019 Feb;208:28-36. doi: 10.1016/j.ahj.2018.11.002. Epub 2018 Nov 9.


Lifestyle Modifications for Preventing and Treating Heart Failure.

Aggarwal M, Bozkurt B, Panjrath G, Aggarwal B, Ostfeld RJ, Barnard ND, Gaggin H, Freeman AM, Allen K, Madan S, Massera D, Litwin SE; American College of Cardiology’s Nutrition and Lifestyle Committee of the Prevention of Cardiovascular Disease Council.

J Am Coll Cardiol. 2018 Nov 6;72(19):2391-2405. doi: 10.1016/j.jacc.2018.08.2160. Review.


One-Year Safety and Clinical Outcomes of a Transcatheter Interatrial Shunt Device for the Treatment of Heart Failure With Preserved Ejection Fraction in the Reduce Elevated Left Atrial Pressure in Patients With Heart Failure (REDUCE LAP-HF I) Trial: A Randomized Clinical Trial.

Shah SJ, Feldman T, Ricciardi MJ, Kahwash R, Lilly S, Litwin S, Nielsen CD, van der Harst P, Hoendermis E, Penicka M, Bartunek J, Fail PS, Kaye DM, Walton A, Petrie MC, Walker N, Basuray A, Yakubov S, Hummel SL, Chetcuti S, Forde-McLean R, Herrmann HC, Burkhoff D, Massaro JM, Cleland JGF, Mauri L.

JAMA Cardiol. 2018 Oct 1;3(10):968-977. doi: 10.1001/jamacardio.2018.2936.


A Clinician's Guide for Trending Cardiovascular Nutrition Controversies: Part II.

Freeman AM, Morris PB, Aspry K, Gordon NF, Barnard ND, Esselstyn CB, Ros E, Devries S, O'Keefe J, Miller M, Ornish D, Williams KA, Batts T, Ostfeld RJ, Litwin S, Aggarwal M, Werner A, Allen K, White B, Kris-Etherton P.

J Am Coll Cardiol. 2018 Jul 31;72(5):553-568. doi: 10.1016/j.jacc.2018.05.030. Review.


NEDD9 promotes oncogenic signaling, a stem/mesenchymal gene signature, and aggressive ovarian cancer growth in mice.

Gabbasov R, Xiao F, Howe CG, Bickel LE, O'Brien SW, Benrubi D, Do TV, Zhou Y, Nicolas E, Cai KQ, Litwin S, Seo S, Golemis EA, Connolly DC.

Oncogene. 2018 Aug;37(35):4854-4870. doi: 10.1038/s41388-018-0296-y. Epub 2018 May 18.


In Vitro and In Vivo evaluation of a novel folate-targeted theranostic nanoemulsion of docetaxel for imaging and improved anticancer activity against ovarian cancers.

Patel NR, Piroyan A, Ganta S, Morse AB, Candiloro KM, Solon AL, Nack AH, Galati CA, Bora C, Maglaty MA, O'Brien SW, Litwin S, Davis B, Connolly DC, Coleman TP.

Cancer Biol Ther. 2018 Jul 3;19(7):554-564. doi: 10.1080/15384047.2017.1395118. Epub 2018 May 8.


A single high-fat meal provokes pathological erythrocyte remodeling and increases myeloperoxidase levels: implications for acute coronary syndrome.

Benson TW, Weintraub NL, Kim HW, Seigler N, Kumar S, Pye J, Horimatsu T, Pellenberg R, Stepp DW, Lucas R, Bogdanov VY, Litwin SE, Brittain JE, Harris RA.

Lab Invest. 2018 Oct;98(10):1300-1310. doi: 10.1038/s41374-018-0038-3. Epub 2018 Mar 23.


To Clip or Not to Clip? Can We Predict Which Patients with Functional Mitral Regurgitation Will Benefit From Transcatheter Mitral Valve Repair?

El Hajj S, Litwin SE.

J Card Fail. 2018 Mar;24(3):146-147. doi: 10.1016/j.cardfail.2018.01.010. Epub 2018 Feb 6. No abstract available.


Diagnostic accuracy of low and high tube voltage coronary CT angiography using an X-ray tube potential-tailored contrast medium injection protocol.

Albrecht MH, Nance JW, Schoepf UJ, Jacobs BE, Bayer RR 2nd, Litwin SE, Reynolds MA, Otani K, Mangold S, Varga-Szemes A, De Santis D, Eid M, Apfaltrer G, Tesche C, Goeller M, Vogl TJ, De Cecco CN.

Eur Radiol. 2018 May;28(5):2134-2142. doi: 10.1007/s00330-017-5150-z. Epub 2017 Nov 27.


Transcatheter Interatrial Shunt Device for the Treatment of Heart Failure With Preserved Ejection Fraction (REDUCE LAP-HF I [Reduce Elevated Left Atrial Pressure in Patients With Heart Failure]): A Phase 2, Randomized, Sham-Controlled Trial.

Feldman T, Mauri L, Kahwash R, Litwin S, Ricciardi MJ, van der Harst P, Penicka M, Fail PS, Kaye DM, Petrie MC, Basuray A, Hummel SL, Forde-McLean R, Nielsen CD, Lilly S, Massaro JM, Burkhoff D, Shah SJ; REDUCE LAP-HF I Investigators and Study Coordinators.

Circulation. 2018 Jan 23;137(4):364-375. doi: 10.1161/CIRCULATIONAHA.117.032094. Epub 2017 Nov 15.


Optimizing donor site closure following bilateral breast reconstruction with abdominal-based free flaps.

Messina NM, Rossi K, Wetherhold LM, Wetherhold MJ, Litwin S, Topham NS, Chang EI.

J Plast Reconstr Aesthet Surg. 2018 Feb;71(2):269-271. doi: 10.1016/j.bjps.2017.10.022. Epub 2017 Nov 2. No abstract available.


Coronary Computed Tomographic Angiography-Derived Fractional Flow Reserve for Therapeutic Decision Making.

Tesche C, Vliegenthart R, Duguay TM, De Cecco CN, Albrecht MH, De Santis D, Langenbach MC, Varga-Szemes A, Jacobs BE, Jochheim D, Baquet M, Bayer RR Nd, Litwin SE, Hoffmann E, Steinberg DH, Schoepf UJ.

Am J Cardiol. 2017 Dec 15;120(12):2121-2127. doi: 10.1016/j.amjcard.2017.08.034. Epub 2017 Sep 19.


Antivenom against Crotalus durissus terrificus venom: Immunochemical reactivity and experimental neutralizing capacity.

Baudou FG, Litwin S, Lanari LC, Laskowicz RD, Damin CF, Chippaux JP, de Roodt AR.

Toxicon. 2017 Dec 15;140:11-17. doi: 10.1016/j.toxicon.2017.10.009. Epub 2017 Oct 16.


Weight and Metabolic Outcomes 12 Years after Gastric Bypass.

Adams TD, Davidson LE, Litwin SE, Kim J, Kolotkin RL, Nanjee MN, Gutierrez JM, Frogley SJ, Ibele AR, Brinton EA, Hopkins PN, McKinlay R, Simper SC, Hunt SC.

N Engl J Med. 2017 Sep 21;377(12):1143-1155. doi: 10.1056/NEJMoa1700459.


Coronary CT Angiography-derived Fractional Flow Reserve.

Tesche C, De Cecco CN, Albrecht MH, Duguay TM, Bayer RR 2nd, Litwin SE, Steinberg DH, Schoepf UJ.

Radiology. 2017 Oct;285(1):17-33. doi: 10.1148/radiol.2017162641.


Coronary Computed Tomographic Angiography-Derived Fractional Flow Reserve Based on Machine Learning for Risk Stratification of Non-Culprit Coronary Narrowings in Patients with Acute Coronary Syndrome.

Duguay TM, Tesche C, Vliegenthart R, De Cecco CN, Lin H, Albrecht MH, Varga-Szemes A, De Santis D, Ebersberger U, Bayer RR Nd, Litwin SE, Hoffmann E, Steinberg DH, Schoepf UJ.

Am J Cardiol. 2017 Oct 15;120(8):1260-1266. doi: 10.1016/j.amjcard.2017.07.008. Epub 2017 Jul 25.


Glucose transporter 4-deficient hearts develop maladaptive hypertrophy in response to physiological or pathological stresses.

Wende AR, Kim J, Holland WL, Wayment BE, O'Neill BT, Tuinei J, Brahma MK, Pepin ME, McCrory MA, Luptak I, Halade GV, Litwin SE, Abel ED.

Am J Physiol Heart Circ Physiol. 2017 Dec 1;313(6):H1098-H1108. doi: 10.1152/ajpheart.00101.2017. Epub 2017 Aug 19.


NK cell dysfunction in chronic lymphocytic leukemia is associated with loss of the mature cells expressing inhibitory killer cell Ig-like receptors.

MacFarlane AW 4th, Jillab M, Smith MR, Alpaugh RK, Cole ME, Litwin S, Millenson MM, Al-Saleem T, Cohen AD, Campbell KS.

Oncoimmunology. 2017 May 19;6(7):e1330235. doi: 10.1080/2162402X.2017.1330235. eCollection 2017.


Two-sample binary phase 2 trials with low type I error and low sample size.

Litwin S, Ross E, Basickes S.

Stat Med. 2017 Sep 20;36(21):3439. doi: 10.1002/sim.7358. No abstract available.


Effect of Adjuvant Chemotherapy on Left Ventricular Remodeling in Women with Newly Diagnosed Primary Breast Cancer: A Pilot Prospective Longitudinal Cardiac Magnetic Resonance Imaging Study.

Avelar E, Truong QA, Inyangetor D, Marfatia R, Yang C, Kaloudis E, Tannenbaum S, Rosito G, Litwin S.

J Thorac Imaging. 2017 Nov;32(6):365-369. doi: 10.1097/RTI.0000000000000285.


Round Valve in an Oval Hole: Right-Sizing Prosthetic Aortic Valves With Preoperative Computed Tomography.

Benton SM Jr, Litwin SE.

Circ Cardiovasc Imaging. 2017 May;10(5). pii: e006404. doi: 10.1161/CIRCIMAGING.117.006404. No abstract available.


Immune Tolerant Chronic Hepatitis B: The Unrecognized Risks.

Kennedy PTF, Litwin S, Dolman GE, Bertoletti A, Mason WS.

Viruses. 2017 Apr 29;9(5). pii: E96. doi: 10.3390/v9050096. Review.


A novel role for the Wnt inhibitor APCDD1 in adipocyte differentiation: Implications for diet-induced obesity.

Yiew NKH, Chatterjee TK, Tang YL, Pellenberg R, Stansfield BK, Bagi Z, Fulton DJ, Stepp DW, Chen W, Patel V, Kamath VM, Litwin SE, Hui DY, Rudich SM, Kim HW, Weintraub NL.

J Biol Chem. 2017 Apr 14;292(15):6312-6324. doi: 10.1074/jbc.M116.758078. Epub 2017 Feb 27.


Multiparity upregulates placental plasminogen and urokinase-type plasminogen activator.

Cortina ME, Litwin S, Rial Hawila MR, Miranda S.

Am J Reprod Immunol. 2017 Apr;77(4). doi: 10.1111/aji.12633. Epub 2017 Feb 3.


Two-sample binary phase 2 trials with low type I error and low sample size.

Litwin S, Basickes S, Ross EA.

Stat Med. 2017 Apr 30;36(9):1383-1394. doi: 10.1002/sim.7226. Epub 2017 Jan 24.


Accuracy of Noncontrast Quiescent-Interval Single-Shot Lower Extremity MR Angiography Versus CT Angiography for Diagnosis of Peripheral Artery Disease: Comparison With Digital Subtraction Angiography.

Varga-Szemes A, Wichmann JL, Schoepf UJ, Suranyi P, De Cecco CN, Muscogiuri G, Caruso D, Yamada RT, Litwin SE, Tesche C, Duguay TM, Giri S, Vliegenthart R, Todoran TM.

JACC Cardiovasc Imaging. 2017 Oct;10(10 Pt A):1116-1124. doi: 10.1016/j.jcmg.2016.09.030. Epub 2017 Jan 18.


Effect of inversion time on the precision of myocardial late gadolinium enhancement quantification evaluated with synthetic inversion recovery MR imaging.

Varga-Szemes A, van der Geest RJ, Schoepf UJ, Spottiswoode BS, De Cecco CN, Muscogiuri G, Wichmann JL, Mangold S, Fuller SR, Maurovich-Horvat P, Merkely B, Litwin SE, Vliegenthart R, Suranyi P.

Eur Radiol. 2017 Aug;27(8):3235-3243. doi: 10.1007/s00330-016-4665-z. Epub 2017 Jan 3.


Prognostic value of CT-derived left atrial and left ventricular measures in patients with acute chest pain.

Takx RAP, Vliegenthart R, Schoepf UJ, Nance JW, Bamberg F, Abro JA, Carr CM, Litwin SE, Apfaltrer P.

Eur J Radiol. 2017 Jan;86:163-168. doi: 10.1016/j.ejrad.2016.11.013. Epub 2016 Nov 8.


Coronary Computed Tomography Angiography-Derived Plaque Quantification in Patients With Acute Coronary Syndrome.

Tesche C, Caruso D, De Cecco CN, Shuler DC, Rames JD, Albrecht MH, Duguay TM, Varga-Szemes A, Jochheim D, Baquet M, Bayer RR, Ebersberger U, Litwin SE, Chiaramida SA, Hoffmann E, Schoepf UJ.

Am J Cardiol. 2017 Mar 1;119(5):712-718. doi: 10.1016/j.amjcard.2016.11.030. Epub 2016 Dec 3.


Small-Cell Carcinoma of the Bladder: 20-Year Single-Institution Retrospective Review.

Jung K, Ghatalia P, Litwin S, Horwitz EM, Uzzo RG, Greenberg RE, Viterbo R, Geynisman DM, Kutikov A, Plimack ER, Smaldone MC, Wong YN, Bilusic M.

Clin Genitourin Cancer. 2017 Jun;15(3):e337-e343. doi: 10.1016/j.clgc.2016.09.005. Epub 2016 Sep 30. Review.


Accuracy and Radiation Dose Reduction Using Low-Voltage Computed Tomography Coronary Artery Calcium Scoring With Tin Filtration.

Tesche C, De Cecco CN, Vliegenthart R, Albrecht MH, Varga-Szemes A, Duguay TM, Ebersberger U, Bayer RR 2nd, Canstein C, Schmidt B, Allmendinger T, Litwin SE, Morris PB, Flohr TG, Hoffmann E, Schoepf UJ.

Am J Cardiol. 2017 Feb 15;119(4):675-680. doi: 10.1016/j.amjcard.2016.10.051. Epub 2016 Nov 16.


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