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Items: 23


Opportunities and Challenges in Implementation of Multiparameter Single Cell Analysis Platforms for Clinical Translation.

Keating SM, Taylor DL, Plant AL, Litwack ED, Kuhn P, Greenspan EJ, Hartshorn CM, Sigman CC, Kelloff GJ, Chang DD, Friberg G, Lee JSH, Kuida K.

Clin Transl Sci. 2018 May;11(3):267-276. doi: 10.1111/cts.12536. Epub 2018 Mar 2. Review.


Considerations for Developing Targeted Therapies in Low-Frequency Molecular Subsets of a Disease.

Schuck RN, Woodcock J, Zineh I, Stein P, Jarow J, Temple R, Permutt T, LaVange L, Beaver JA, Charlab R, Blumenthal GM, Dorff SE, Leptak C, Lemery S, Rogers H, Chowdhury B, Litwack ED, Pacanowski M.

Clin Pharmacol Ther. 2018 Aug;104(2):282-289. doi: 10.1002/cpt.1041. Epub 2018 Feb 23.


Precision medicine in the age of big data: The present and future role of large-scale unbiased sequencing in drug discovery and development.

Vicini P, Fields O, Lai E, Litwack ED, Martin AM, Morgan TM, Pacanowski MA, Papaluca M, Perez OD, Ringel MS, Robson M, Sakul H, Vockley J, Zaks T, Dolsten M, S√łgaard M.

Clin Pharmacol Ther. 2016 Feb;99(2):198-207. doi: 10.1002/cpt.293. Epub 2015 Dec 19. Review.


FDA oversight of laboratory-developed tests will facilitate adoption of pharmacogenetic testing into routine clinical care.

Hillebrenner E, Litwack E, Bradley P, Donigan K, Lowe T, Serrano K, Kelm K, Mansfield E, Gutierrez A.

J Clin Pharmacol. 2015 Jul;55(7):728-30. doi: 10.1002/jcph.521. No abstract available.


The FDA and genetic testing.

Litwack ED, Mansfield E, Shuren J.

N Engl J Med. 2015 Jun 4;372(23):2273-4. doi: 10.1056/NEJMc1504604. Epub 2015 May 27. No abstract available.


Nuclear factor I and cerebellar granule neuron development: an intrinsic-extrinsic interplay.

Kilpatrick DL, Wang W, Gronostajski R, Litwack ED.

Cerebellum. 2012 Mar;11(1):41-9. doi: 10.1007/s12311-010-0227-0. Review.


Mesenchymal nuclear factor I B regulates cell proliferation and epithelial differentiation during lung maturation.

Hsu YC, Osinski J, Campbell CE, Litwack ED, Wang D, Liu S, Bachurski CJ, Gronostajski RM.

Dev Biol. 2011 Jun 15;354(2):242-52. doi: 10.1016/j.ydbio.2011.04.002. Epub 2011 Apr 13.


Targets of the nuclear factor I regulon involved in early and late development of postmitotic cerebellar granule neurons.

Wang W, Crandall JE, Litwack ED, Gronostajski RM, Kilpatrick DL.

J Neurosci Res. 2010 Feb 1;88(2):258-65. doi: 10.1002/jnr.22199.


Absence of the transcription factor Nfib delays the formation of the basilar pontine and other mossy fiber nuclei.

Kumbasar A, Plachez C, Gronostajski RM, Richards LJ, Litwack ED.

J Comp Neurol. 2009 Mar 1;513(1):98-112. doi: 10.1002/cne.21943.


The transcription factor Nfix is essential for normal brain development.

Campbell CE, Piper M, Plachez C, Yeh YT, Baizer JS, Osinski JM, Litwack ED, Richards LJ, Gronostajski RM.

BMC Dev Biol. 2008 May 13;8:52. doi: 10.1186/1471-213X-8-52.


Nuclear factor I coordinates multiple phases of cerebellar granule cell development via regulation of cell adhesion molecules.

Wang W, Mullikin-Kilpatrick D, Crandall JE, Gronostajski RM, Litwack ED, Kilpatrick DL.

J Neurosci. 2007 Jun 6;27(23):6115-27.


Novel IgCAM, MDGA1, expressed in unique cortical area- and layer-specific patterns and transiently by distinct forebrain populations of Cajal-Retzius neurons.

Takeuchi A, Hamasaki T, Litwack ED, O'Leary DD.

Cereb Cortex. 2007 Jul;17(7):1531-41. Epub 2006 Sep 7.


The transcription factor gene Nfib is essential for both lung maturation and brain development.

Steele-Perkins G, Plachez C, Butz KG, Yang G, Bachurski CJ, Kinsman SL, Litwack ED, Richards LJ, Gronostajski RM.

Mol Cell Biol. 2005 Jan;25(2):685-98.


Identification and characterization of two novel brain-derived immunoglobulin superfamily members with a unique structural organization.

Litwack ED, Babey R, Buser R, Gesemann M, O'Leary DD.

Mol Cell Neurosci. 2004 Feb;25(2):263-74.


Modulation of the F-actin cytoskeleton by c-Abl tyrosine kinase in cell spreading and neurite extension.

Woodring PJ, Litwack ED, O'Leary DD, Lucero GR, Wang JY, Hunter T.

J Cell Biol. 2002 Mar 4;156(5):879-92. Epub 2002 Feb 25.


Identification of candidate genes for controlling development of the basilar pons by differential display PCR.

Gesemann M, Litwack ED, Yee KT, Christen U, O'Leary DD.

Mol Cell Neurosci. 2001 Jul;18(1):1-12.


Heparan sulfate proteoglycans as adhesive and anti-invasive molecules. Syndecans and glypican have distinct functions.

Liu W, Litwack ED, Stanley MJ, Langford JK, Lander AD, Sanderson RD.

J Biol Chem. 1998 Aug 28;273(35):22825-32.


Expression of the heparan sulfate proteoglycan glypican-1 in the developing rodent.

Litwack ED, Ivins JK, Kumbasar A, Paine-Saunders S, Stipp CS, Lander AD.

Dev Dyn. 1998 Jan;211(1):72-87.


Wide distribution of homologs of Escherichia coli Kdp K+-ATPase among gram-negative bacteria.

Walderhaug MO, Litwack ED, Epstein W.

J Bacteriol. 1989 Feb;171(2):1192-5.

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