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Items: 44

1.

Targeting B-Raf inhibitor resistant melanoma with novel cell penetrating peptide disrupters of PDE8A - C-Raf.

Blair CM, Walsh NM, Littman BH, Marcoux FW, Baillie GS.

BMC Cancer. 2019 Mar 25;19(1):266. doi: 10.1186/s12885-019-5489-4.

2.

Anti-inflammatory Activity of MTL-CEBPA, a Small Activating RNA Drug, in LPS-Stimulated Monocytes and Humanized Mice.

Zhou J, Li H, Xia X, Herrera A, Pollock N, Reebye V, Sodergren MH, Dorman S, Littman BH, Doogan D, Huang KW, Habib R, Blakey D, Habib NA, Rossi JJ.

Mol Ther. 2019 May 8;27(5):999-1016. doi: 10.1016/j.ymthe.2019.02.018. Epub 2019 Feb 26.

3.

An NIH National Center for Advancing Translational Sciences: is a focus on drug discovery the best option?

Littman BH.

Nat Rev Drug Discov. 2011 Jun;10(6):471. doi: 10.1038/nrd3357-c1. Epub 2011 May 20. No abstract available.

PMID:
21597471
5.

Translational strategies to implement personalized medicine: rheumatoid arthritis examples.

Littman BH.

Per Med. 2009 Jul;6(4):429-437. doi: 10.2217/pme.09.17.

PMID:
29783543
6.

Tocilizumab and missed personalized medicine opportunities for patients with rheumatoid arthritis?

Littman BH.

Arthritis Rheum. 2009 May;60(5):1565-6. doi: 10.1002/art.24474. No abstract available.

7.

What's next in translational medicine?

Littman BH, Di Mario L, Plebani M, Marincola FM.

Clin Sci (Lond). 2007 Feb;112(4):217-27. Review.

PMID:
17223795
8.

Experiences with dose finding in patients in early drug development: the use of biomarkers in early decision making.

Sultana SR, Marshall S, Davis J, Littman BH.

Ernst Schering Res Found Workshop. 2007;(59):65-79. Review.

PMID:
17117715
9.

The ultimate model organism: progress in experimental medicine.

Littman BH, Williams SA.

Nat Rev Drug Discov. 2005 Aug;4(8):631-8. Review.

PMID:
16056389
10.

Prevention of organ allograft rejection by a specific Janus kinase 3 inhibitor.

Changelian PS, Flanagan ME, Ball DJ, Kent CR, Magnuson KS, Martin WH, Rizzuti BJ, Sawyer PS, Perry BD, Brissette WH, McCurdy SP, Kudlacz EM, Conklyn MJ, Elliott EA, Koslov ER, Fisher MB, Strelevitz TJ, Yoon K, Whipple DA, Sun J, Munchhof MJ, Doty JL, Casavant JM, Blumenkopf TA, Hines M, Brown MF, Lillie BM, Subramanyam C, Shang-Poa C, Milici AJ, Beckius GE, Moyer JD, Su C, Woodworth TG, Gaweco AS, Beals CR, Littman BH, Fisher DA, Smith JF, Zagouras P, Magna HA, Saltarelli MJ, Johnson KS, Nelms LF, Des Etages SG, Hayes LS, Kawabata TT, Finco-Kent D, Baker DL, Larson M, Si MS, Paniagua R, Higgins J, Holm B, Reitz B, Zhou YJ, Morris RE, O'Shea JJ, Borie DC.

Science. 2003 Oct 31;302(5646):875-8.

11.

Mapping of local renal blood flow with PET and H(2)(15)O.

Alpert NM, Rabito CA, Correia DJ, Babich JW, Littman BH, Tompkins RG, Rubin NT, Rubin RH, Fischman AJ.

J Nucl Med. 2002 Apr;43(4):470-5.

12.

Analysis of changes in acute-phase plasma proteins in an acute inflammatory response and in rheumatoid arthritis using two-dimensional gel electrophoresis.

Doherty NS, Littman BH, Reilly K, Swindell AC, Buss JM, Anderson NL.

Electrophoresis. 1998 Feb;19(2):355-63.

PMID:
9548303
13.

Effect of tenidap on metalloproteinase gene expression in rheumatoid arthritis: a synovial biopsy study.

Littman BH, Schumacher HR Jr, Boyle DL, Weisman MH, Firestein GS.

J Clin Rheumatol. 1997 Aug;3(4):194-202.

PMID:
19078187
14.

Steroid sparing activity of tenidap in patients with polymyalgia rheumatica: a multicenter double blind randomized placebo controlled study.

Littman BH, Bjarnason D, Bryant G, Engelbrecht J, Cohen M, Mertz L, Weaver A, Hunder GG.

J Rheumatol. 1995 Jun;22(6):1097-103.

PMID:
7674236
15.

Rheumatoid arthritis treated with tenidap and piroxicam. Clinical associations with cytokine modulation by tenidap.

Littman BH, Drury CE, Zimmerer RO, Stack CB, Law CG.

Arthritis Rheum. 1995 Jan;38(1):29-37.

PMID:
7818568
17.

Effects of gold sodium thiomalate and tenidap sodium (CP-66,248-2) on a model of macrophage differentiation using HL-60 cells.

Littman BH, Carlson PL, Loose LD, Sanders KM.

Arthritis Rheum. 1990 Jan;33(1):29-36.

PMID:
2154231
18.

Linear scleroderma: a response to neurologic injury? Report and literature review.

Littman BH.

J Rheumatol. 1989 Aug;16(8):1135-40. Review.

PMID:
2685298
19.

Regulation of monocyte/macrophage C2 production and HLA-DR expression by IL-4 (BSF-1) and IFN-gamma.

Littman BH, Dastvan FF, Carlson PL, Sanders KM.

J Immunol. 1989 Jan 15;142(2):520-5.

PMID:
2492049
20.

Problems+Solutions.

Camishion G, deShazo RD, Littman BH.

Postgrad Med. 1988 Dec;84(8):35-7. doi: 10.1080/00325481.1988.11700504. No abstract available.

PMID:
27191754
22.

Effects of gold sodium thiomalate on interferon stimulation of C2 synthesis and HLA-DR expression by human monocytes.

Sanders KM, Carlson PL, Littman BH.

Arthritis Rheum. 1987 Sep;30(9):1032-9.

PMID:
3117066
23.

Correlation of immunoglobulin and C reactive protein levels in ankylosing spondylitis and rheumatoid arthritis.

Sanders KM, Hertzman A, Escobar MR, Littman BH.

Ann Rheum Dis. 1987 Apr;46(4):273-6.

24.
25.

Effects of gold sodium thiomalate on functional correlates of human monocyte maturation.

Littman BH, Hall RE.

Arthritis Rheum. 1985 Dec;28(12):1384-92.

PMID:
3002397
26.

The fibrinogenolytic activity of purified tryptase from human lung mast cells.

Schwartz LB, Bradford TR, Littman BH, Wintroub BU.

J Immunol. 1985 Oct;135(4):2762-7.

PMID:
3161948
27.

Asymptomatic hyperuricemia. The case for benign neglect.

Littman BH.

Postgrad Med. 1985 May 1;77(6):221-4. No abstract available.

PMID:
3991381
28.
29.

Lymphokine and phorbol (PMA) regulation of complement (C2) synthesis using U937.

Littman BH, Hall RE, Muchmore AV.

Cell Immunol. 1983 Feb 15;76(1):189-95.

PMID:
6831567
30.
31.

Immunological considerations in connective tissue diseases.

Littman BH.

Triangle. 1980;19(2):53-60. No abstract available.

PMID:
6969479
32.

Monocyte complement stimulator: a T-lymphocyte product which stimulates synthesis of the second complement component (C2).

Littman BH, Ruddy S.

Cell Immunol. 1979 Mar 15;43(2):388-97. No abstract available.

PMID:
314346
33.

An assay for human lymphocyte mitogenic factor: B-lymphocyte stimulation by a T-lymphocyte product.

Littman BH, David JR.

Cell Immunol. 1978 Sep;39(2):374-87. No abstract available.

PMID:
308860
34.

Hypogammaglobulinemia followed by aplastic anemia with suppressor lymphocytes: a case report.

Littman BH, Cooke CL, Hoffman R.

Clin Immunol Immunopathol. 1978 Jul;10(3):344-9. No abstract available.

PMID:
307476
35.

Modulation of cellular immune function in vitro by histamine receptor-bearing lymphocytes: mechanism of action.

Rocklin RE, Greineder D, Littman BH, Melmon KL.

Cell Immunol. 1978 Apr;37(1):162-73. No abstract available.

PMID:
350418
36.

Ibuprofen-induced meningitis in systemic lupus erythematosus.

Widener HL, Littman BH.

JAMA. 1978 Mar 13;239(11):1062-4.

PMID:
304902
37.

Transfer factor treatment of chronic mucocutaneous candidiasis: requirement for donor reactivity to candida antigen.

Littman BH, Rocklin RE, Parkman R, David JR.

Clin Immunol Immunopathol. 1978 Jan;9(1):97-110. No abstract available.

PMID:
618414
39.

The effect of purified alpha-fetoprotein on in vitro assays of cell-mediated immunity.

Littman BH, Alpert E, Rocklin RE.

Cell Immunol. 1977 Apr;30(1):35-42. No abstract available.

PMID:
67905
40.
41.

Migration inhibitory factor (MIF) and proliferative responses by human lymphocyte subpopulations separated by sheep erythrocyte rosette formation.

Littman BH, David JR, Rocklin RE.

Cell Immunol. 1976 Jun 15;24(2):241-9. No abstract available.

PMID:
59635
42.

Acquired cellular immunity: extracellular killing of Listeria monocytogenes by a product of immunologically activated macrophages.

Bast RC Jr, Cleveland RP, Littman BH, Zbar B, Rapp HJ.

Cell Immunol. 1974 Feb;10(2):248-59. No abstract available.

PMID:
4218128
43.

Tumor-specific, cell-mediated immunity in guinea pigs with tumors.

Littman BH, Meltzer MS, Cleveland RP, Zbar B, Rapp HJ.

J Natl Cancer Inst. 1973 Nov;51(5):1627-35. No abstract available.

PMID:
4762937
44.

Cell-mediated tumor immunity measured in vitro and in vivo with soluble tumor-specific antigens.

Meltzer MS, Oppenheim JJ, Littman BH, Leonard EJ, Rapp HJ.

J Natl Cancer Inst. 1972 Sep;49(3):727-34. No abstract available.

PMID:
4345967

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