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Items: 44

1.

Tissue Inhibitor of Metalloproteinase-3 (TIMP-3) induces FAS dependent apoptosis in human vascular smooth muscle cells.

English WR, Ireland-Zecchini H, Baker AH, Littlewood TD, Bennett MR, Murphy G.

PLoS One. 2018 Apr 4;13(4):e0195116. doi: 10.1371/journal.pone.0195116. eCollection 2018.

2.

Myc Cooperates with Ras by Programming Inflammation and Immune Suppression.

Kortlever RM, Sodir NM, Wilson CH, Burkhart DL, Pellegrinet L, Brown Swigart L, Littlewood TD, Evan GI.

Cell. 2017 Nov 30;171(6):1301-1315.e14. doi: 10.1016/j.cell.2017.11.013.

3.

Determination of the physiological and pathological roles of E2F3 in adult tissues.

Gamper I, Burkhart DL, Bywater MJ, Garcia D, Wilson CH, Kreuzaler PA, Arends MJ, Zheng YW, Perfetto A, Littlewood TD, Evan GI.

Sci Rep. 2017 Aug 30;7(1):9932. doi: 10.1038/s41598-017-09494-6.

4.

Re-engineering the Pancreas Tumor Microenvironment: A "Regenerative Program" Hacked.

Evan GI, Hah N, Littlewood TD, Sodir NM, Campos T, Downes M, Evans RM.

Clin Cancer Res. 2017 Apr 1;23(7):1647-1655. doi: 10.1158/1078-0432.CCR-16-3275. Review.

5.

SOX2 Drives Bronchial Dysplasia in a Novel Organotypic Model of Early Human Squamous Lung Cancer.

Correia LL, Johnson JA, McErlean P, Bauer J, Farah H, Rassl DM, Rintoul RC, Sethi T, Lavender P, Rawlins EL, Littlewood TD, Evan GI, McCaughan FM.

Am J Respir Crit Care Med. 2017 Jun 1;195(11):1494-1508. doi: 10.1164/rccm.201510-2084OC.

6.

Identification of MYC-Dependent Transcriptional Programs in Oncogene-Addicted Liver Tumors.

Kress TR, Pellanda P, Pellegrinet L, Bianchi V, Nicoli P, Doni M, Recordati C, Bianchi S, Rotta L, Capra T, RavĂ  M, Verrecchia A, Radaelli E, Littlewood TD, Evan GI, Amati B.

Cancer Res. 2016 Jun 15;76(12):3463-72. doi: 10.1158/0008-5472.CAN-16-0316. Epub 2016 Apr 13.

7.

The kinetics of ER fusion protein activation in vivo.

Wilson CH, Gamper I, Perfetto A, Auw J, Littlewood TD, Evan GI.

Oncogene. 2014 Oct 2;33(40):4877-80. doi: 10.1038/onc.2014.78. Epub 2014 Mar 24.

8.

Methods for determining Myc-induced apoptosis.

Lu D, Littlewood TD.

Methods Mol Biol. 2013;1012:85-98. doi: 10.1007/978-1-62703-429-6_7.

PMID:
24006060
9.

All things to all people.

Littlewood TD, Kreuzaler P, Evan GI.

Cell. 2012 Sep 28;151(1):11-3. doi: 10.1016/j.cell.2012.09.006.

10.

Smooth muscle cell apoptosis promotes vessel remodeling and repair via activation of cell migration, proliferation, and collagen synthesis.

Yu H, Clarke MC, Figg N, Littlewood TD, Bennett MR.

Arterioscler Thromb Vasc Biol. 2011 Nov;31(11):2402-9. doi: 10.1161/ATVBAHA.111.235622.

PMID:
21885847
11.

Chronic apoptosis of vascular smooth muscle cells accelerates atherosclerosis and promotes calcification and medial degeneration.

Clarke MC, Littlewood TD, Figg N, Maguire JJ, Davenport AP, Goddard M, Bennett MR.

Circ Res. 2008 Jun 20;102(12):1529-38. doi: 10.1161/CIRCRESAHA.108.175976. Epub 2008 May 22.

PMID:
18497329
12.

Akt regulates the survival of vascular smooth muscle cells via inhibition of FoxO3a and GSK3.

Allard D, Figg N, Bennett MR, Littlewood TD.

J Biol Chem. 2008 Jul 11;283(28):19739-47. doi: 10.1074/jbc.M710098200. Epub 2008 May 5.

13.

Oxidative stress regulates IGF1R expression in vascular smooth-muscle cells via p53 and HDAC recruitment.

Kavurma MM, Figg N, Bennett MR, Mercer J, Khachigian LM, Littlewood TD.

Biochem J. 2007 Oct 1;407(1):79-87.

14.

Foxing smooth muscle cells: FOXO3a-CYR61 connection.

Littlewood TD, Bennett MR.

Circ Res. 2007 Feb 16;100(3):302-4. No abstract available.

PMID:
17307969
15.

Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosis.

Clarke MC, Figg N, Maguire JJ, Davenport AP, Goddard M, Littlewood TD, Bennett MR.

Nat Med. 2006 Sep;12(9):1075-80. Epub 2006 Aug 6.

PMID:
16892061
16.

Apoptotic cell death in atherosclerosis.

Littlewood TD, Bennett MR.

Curr Opin Lipidol. 2003 Oct;14(5):469-75. Review.

PMID:
14501585
17.

Chromosomal and extrachromosomal instability of the cyclin D2 gene is induced by Myc overexpression.

Mai S, Hanley-Hyde J, Rainey GJ, Kuschak TI, Paul JT, Littlewood TD, Mischak H, Stevens LM, Henderson DW, Mushinski JF.

Neoplasia. 1999 Aug;1(3):241-52.

18.

Use of retroviruses to express exogenous genes in vascular smooth muscle cells.

Littlewood TD, Pelengaris SA.

Methods Mol Med. 1999;30:323-41. doi: 10.1385/1-59259-247-3:323.

PMID:
21341037
19.

Suppression of c-Myc-induced apoptosis by the Epstein-Barr virus gene product BHRF1.

Fanidi A, Hancock DC, Littlewood TD.

J Virol. 1998 Oct;72(10):8392-5.

20.

Increased sensitivity of human vascular smooth muscle cells from atherosclerotic plaques to p53-mediated apoptosis.

Bennett MR, Littlewood TD, Schwartz SM, Weissberg PL.

Circ Res. 1997 Oct;81(4):591-9.

PMID:
9314841
21.

Large induction of c-Myc is not essential for the mitogenic response of Swiss 3T3 fibroblasts.

Mehmet H, Littlewood TD, Sinnett-Smith J, Moore JP, Evan GI, Rozengurt E.

Cell Growth Differ. 1997 Feb;8(2):187-93.

22.
23.

Inducible site-directed recombination in mouse embryonic stem cells.

Zhang Y, Riesterer C, Ayrall AM, Sablitzky F, Littlewood TD, Reth M.

Nucleic Acids Res. 1996 Feb 15;24(4):543-8.

24.

A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins.

Littlewood TD, Hancock DC, Danielian PS, Parker MG, Evan GI.

Nucleic Acids Res. 1995 May 25;23(10):1686-90.

25.

Transcription factors 2: helix-loop-helix.

Littlewood TD, Evan GI.

Protein Profile. 1995;2(6):621-702. Review. No abstract available.

PMID:
7553065
26.

Down-regulation of the c-myc proto-oncogene in inhibition of vascular smooth-muscle cell proliferation: a signal for growth arrest?

Bennett MR, Littlewood TD, Hancock DC, Evan GI, Newby AC.

Biochem J. 1994 Sep 15;302 ( Pt 3):701-8.

27.

Transcription factors 2: helix-loop-helix.

Littlewood TD, Evan GI.

Protein Profile. 1994;1(6):635-709. Review. No abstract available.

PMID:
8624823
28.

The c-Myc protein induces cell cycle progression and apoptosis through dimerization with Max.

Amati B, Littlewood TD, Evan GI, Land H.

EMBO J. 1993 Dec 15;12(13):5083-7.

29.

The role of c-myc in cell growth.

Evan GI, Littlewood TD.

Curr Opin Genet Dev. 1993 Feb;3(1):44-9. Review.

PMID:
8453273
30.

Oncogenic activity of the c-Myc protein requires dimerization with Max.

Amati B, Brooks MW, Levy N, Littlewood TD, Evan GI, Land H.

Cell. 1993 Jan 29;72(2):233-45.

PMID:
8425220
31.

Transcriptional activation by the human c-Myc oncoprotein in yeast requires interaction with Max.

Amati B, Dalton S, Brooks MW, Littlewood TD, Evan GI, Land H.

Nature. 1992 Oct 1;359(6394):423-6.

PMID:
1406955
32.

Max and c-Myc/Max DNA-binding activities in cell extracts.

Littlewood TD, Amati B, Land H, Evan GI.

Oncogene. 1992 Sep;7(9):1783-92.

PMID:
1501888
33.

Induction of apoptosis in fibroblasts by c-myc protein.

Evan GI, Wyllie AH, Gilbert CS, Littlewood TD, Land H, Brooks M, Waters CM, Penn LZ, Hancock DC.

Cell. 1992 Apr 3;69(1):119-28.

PMID:
1555236
34.

c-myc protein expression in untransformed fibroblasts.

Waters CM, Littlewood TD, Hancock DC, Moore JP, Evan GI.

Oncogene. 1991 May;6(5):797-805.

PMID:
2052358
35.

Domains of human c-myc protein required for autosuppression and cooperation with ras oncogenes are overlapping.

Penn LJ, Brooks MW, Laufer EM, Littlewood TD, Morgenstern JP, Evan GI, Lee WM, Land H.

Mol Cell Biol. 1990 Sep;10(9):4961-6.

36.

The role of myc oncogenes in cell growth and differentiation.

Littlewood TD, Evan GI.

Adv Dent Res. 1990 Jun;4:69-79. Review. Erratum in: Adv Dent Res 1991 Dec;5:87.

PMID:
2206213
37.

A sensitive enzyme-linked immunosorbence assay for the c-fos and v-fos oncoproteins.

Moore JP, Littlewood TD, Hancock DC, Evan GI.

Biochim Biophys Acta. 1988 Apr 14;965(1):60-7.

PMID:
3126820
38.

Immunological probes in the analysis of myc protein expression.

Evan GI, Moore JP, Ibson JM, Waters CM, Hancock DC, Littlewood TD.

Curr Top Microbiol Immunol. 1988;141:189-201. No abstract available.

PMID:
3063442
39.

Characterization of a heat shock-induced insoluble complex in the nuclei of cells.

Littlewood TD, Hancock DC, Evan GI.

J Cell Sci. 1987 Aug;88 ( Pt 1):65-72.

40.

A sensitive and quantitative enzyme-linked immunosorbence assay for the c-myc and N-myc oncoproteins.

Moore JP, Hancock DC, Littlewood TD, Evan GI.

Oncogene Res. 1987;2(1):65-80.

PMID:
3333275
41.

Characterisation of human myc proteins.

Evan GI, Hancock DC, Littlewood TD, Gee NS.

Curr Top Microbiol Immunol. 1986;132:362-74. No abstract available.

PMID:
3539540
42.

Chromatin structure of transcriptionally active and inactive human c-myc alleles.

Dyson PJ, Littlewood TD, Forster A, Rabbitts TH.

EMBO J. 1985 Nov;4(11):2885-91.

43.

Preliminary report on the presence of RNA-dependent DNA polymerase in canine milk.

Littlewood TD, Tomley FM, Owen LN.

Res Vet Sci. 1984 Jul;37(1):97-100.

PMID:
6206535
44.

Long term tissue cultures and cell lines of neoplasms in domesticated animals.

Owen LN, Doyle A, Littlewood TD.

J Comp Pathol. 1981 Jan;91(1):159-63. No abstract available.

PMID:
7343573

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