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Items: 1 to 50 of 326

1.

Microfluidic capillary zone electrophoresis mass spectrometry analysis of alkaloids in Lobelia cardinalis transgenic and mutant plant cell cultures.

Kelley ZD, Rogers DT, Littleton JM, Lynn BC.

Electrophoresis. 2019 Sep 1. doi: 10.1002/elps.201900220. [Epub ahead of print]

PMID:
31475363
2.

Glial Ca2+signaling links endocytosis to K+ buffering around neuronal somas to regulate excitability.

Weiss S, Melom JE, Ormerod KG, Zhang YV, Littleton JT.

Elife. 2019 Apr 26;8. pii: e44186. doi: 10.7554/eLife.44186.

3.

Neurons regulate synaptic strength through homeostatic scaling of active zones.

Cunningham KL, Littleton JT.

J Cell Biol. 2019 May 6;218(5):1434-1435. doi: 10.1083/jcb.201903065. Epub 2019 Apr 12.

PMID:
30979798
4.

Identification of a new SYT2 variant validates an unusual distal motor neuropathy phenotype.

Montes-Chinea NI, Guan Z, Coutts M, Vidal C, Courel S, Rebelo AP, Abreu L, Zuchner S, Littleton JT, Saporta MA.

Neurol Genet. 2018 Oct 22;4(6):e282. doi: 10.1212/NXG.0000000000000282. eCollection 2018 Dec.

5.

A palaeopathological analysis of skeletal remains from Bronze Age Mongolia.

Karstens S, Littleton J, Frohlich B, Amgaluntugs T, Pearlstein K, Hunt D.

Homo. 2018 Nov;69(6):324-334. doi: 10.1016/j.jchb.2018.11.002. Epub 2018 Nov 23.

PMID:
30501896
6.

Bronze Age population dynamics and the rise of dairy pastoralism on the eastern Eurasian steppe.

Jeong C, Wilkin S, Amgalantugs T, Bouwman AS, Taylor WTT, Hagan RW, Bromage S, Tsolmon S, Trachsel C, Grossmann J, Littleton J, Makarewicz CA, Krigbaum J, Burri M, Scott A, Davaasambuu G, Wright J, Irmer F, Myagmar E, Boivin N, Robbeets M, Rühli FJ, Krause J, Frohlich B, Hendy J, Warinner C.

Proc Natl Acad Sci U S A. 2018 Nov 27;115(48):E11248-E11255. doi: 10.1073/pnas.1813608115. Epub 2018 Nov 5.

7.

Postsynaptic Syntaxin 4 negatively regulates the efficiency of neurotransmitter release.

Harris KP, Littleton JT, Stewart BA.

J Neurogenet. 2018 Sep;32(3):221-229. doi: 10.1080/01677063.2018.1501372. Epub 2018 Sep 3.

8.

Electrical resistivity of liquid Fe to 12 GPa: Implications for heat flow in cores of terrestrial bodies.

Silber RE, Secco RA, Yong W, Littleton JAH.

Sci Rep. 2018 Jul 17;8(1):10758. doi: 10.1038/s41598-018-28921-w.

9.

Characterization of developmental and molecular factors underlying release heterogeneity at Drosophila synapses.

Akbergenova Y, Cunningham KL, Zhang YV, Weiss S, Littleton JT.

Elife. 2018 Jul 10;7. pii: e38268. doi: 10.7554/eLife.38268.

10.

Social group dynamics predict stress variability among children in a New Zealand classroom.

Spray J, Floyd B, Littleton J, Trnka S, Mattison S.

Homo. 2018 Mar;69(1-2):50-61. doi: 10.1016/j.jchb.2018.03.005. Epub 2018 Mar 27.

PMID:
29705502
11.
12.

A synaptotagmin suppressor screen indicates SNARE binding controls the timing and Ca2+ cooperativity of vesicle fusion.

Guan Z, Bykhovskaia M, Jorquera RA, Sutton RB, Akbergenova Y, Littleton JT.

Elife. 2017 Sep 12;6. pii: e28409. doi: 10.7554/eLife.28409.

13.

Adsorption and Recovery of Polyphenolic Flavonoids Using TiO2-Functionalized Mesoporous Silica Nanoparticles.

Khan MA, Wallace WT, Islam SZ, Nagpure S, Strzalka J, Littleton JM, Rankin SE, Knutson BL.

ACS Appl Mater Interfaces. 2017 Sep 20;9(37):32114-32125. doi: 10.1021/acsami.7b09510. Epub 2017 Sep 5.

PMID:
28825464
14.

Dental wear and age grading at Roonka, South Australia.

Littleton J.

Am J Phys Anthropol. 2017 Jul;163(3):519-530. doi: 10.1002/ajpa.23226. Epub 2017 Apr 4.

PMID:
28374451
15.

Astrocyte Ca2+ Influx Negatively Regulates Neuronal Activity.

Zhang YV, Ormerod KG, Littleton JT.

eNeuro. 2017 Mar 10;4(2). pii: ENEURO.0340-16.2017. doi: 10.1523/ENEURO.0340-16.2017. eCollection 2017 Mar-Apr.

16.

Pathogenic Huntington Alters BMP Signaling and Synaptic Growth through Local Disruptions of Endosomal Compartments.

Akbergenova Y, Littleton JT.

J Neurosci. 2017 Mar 22;37(12):3425-3439. doi: 10.1523/JNEUROSCI.2752-16.2017. Epub 2017 Feb 24.

17.

Complexin Mutants Reveal Partial Segregation between Recycling Pathways That Drive Evoked and Spontaneous Neurotransmission.

Sabeva N, Cho RW, Vasin A, Gonzalez A, Littleton JT, Bykhovskaia M.

J Neurosci. 2017 Jan 11;37(2):383-396. doi: 10.1523/JNEUROSCI.1854-16.2016.

18.

Neurotoxicity Pathways in Drosophila Models of the Polyglutamine Disorders.

Krench M, Littleton JT.

Curr Top Dev Biol. 2017;121:201-223. doi: 10.1016/bs.ctdb.2016.07.006. Epub 2016 Aug 4. Review.

PMID:
28057300
19.

Interaction of the Complexin Accessory Helix with Synaptobrevin Regulates Spontaneous Fusion.

Vasin A, Volfson D, Littleton JT, Bykhovskaia M.

Biophys J. 2016 Nov 1;111(9):1954-1964. doi: 10.1016/j.bpj.2016.09.017.

20.

Target-directed discovery and production of pharmaceuticals in transgenic mutant plant cells.

Brown DP, Rogers DT, Gunjan SK, Gerhardt GA, Littleton JM.

J Biotechnol. 2016 Nov 20;238:9-14. doi: 10.1016/j.jbiotec.2016.09.007. Epub 2016 Sep 13.

21.

Characterization of axonal transport defects in Drosophila Huntingtin mutants.

Weiss KR, Littleton JT.

J Neurogenet. 2016 Sep - Dec;30(3-4):212-221. Epub 2016 Jul 22.

22.

A Drosophila model of Huntington disease-like 2 exhibits nuclear toxicity and distinct pathogenic mechanisms from Huntington disease.

Krench M, Cho RW, Littleton JT.

Hum Mol Genet. 2016 Aug 1;25(15):3164-3177. doi: 10.1093/hmg/ddw166. Epub 2016 Jun 10.

23.

Shank Modulates Postsynaptic Wnt Signaling to Regulate Synaptic Development.

Harris KP, Akbergenova Y, Cho RW, Baas-Thomas MS, Littleton JT.

J Neurosci. 2016 May 25;36(21):5820-32. doi: 10.1523/JNEUROSCI.4279-15.2016.

24.

The postsynaptic t-SNARE Syntaxin 4 controls traffic of Neuroligin 1 and Synaptotagmin 4 to regulate retrograde signaling.

Harris KP, Zhang YV, Piccioli ZD, Perrimon N, Littleton JT.

Elife. 2016 May 25;5. pii: e13881. doi: 10.7554/eLife.13881.

25.

Novel multifunctional pharmacology of lobinaline, the major alkaloid from Lobelia cardinalis.

Brown DP, Rogers DT, Pomerleau F, Siripurapu KB, Kulshrestha M, Gerhardt GA, Littleton JM.

Fitoterapia. 2016 Jun;111:109-23. doi: 10.1016/j.fitote.2016.04.013. Epub 2016 Apr 20.

26.

Animal Models for Medication Development and Application to Treat Fetal Alcohol Effects.

Barron S, Hawkey A, Fields L, Littleton JM.

Int Rev Neurobiol. 2016;126:423-40. doi: 10.1016/bs.irn.2016.02.002. Epub 2016 Mar 4. Review.

PMID:
27055621
27.

Drosophila Homolog of Human KIF22 at the Autism-Linked 16p11.2 Loci Influences Synaptic Connectivity at Larval Neuromuscular Junctions.

Park SM, Littleton JT, Park HR, Lee JH.

Exp Neurobiol. 2016 Feb;25(1):33-9. doi: 10.5607/en.2016.25.1.33. Epub 2016 Feb 22.

28.

Use of alpha-, beta-Estrogen Receptor as a "new tool" for detection of specific small molecule activity.

Gunjan SK, Rogers DT, Zhang J, Yun KY, Falcone DL, Littleton J.

Plant Mol Biol Report. 2015 Dec 1;33(6):1837-1843. Epub 2015 Mar 26.

29.

Phosphorylation of Complexin by PKA Regulates Activity-Dependent Spontaneous Neurotransmitter Release and Structural Synaptic Plasticity.

Cho RW, Buhl LK, Volfson D, Tran A, Li F, Akbergenova Y, Littleton JT.

Neuron. 2015 Nov 18;88(4):749-61. doi: 10.1016/j.neuron.2015.10.011.

30.

The Dietary Flavonoid Rhamnetin Inhibits Both Inflammation and Excitotoxicity During Ethanol Withdrawal in Rat Organotypic Hippocampal Slice Cultures.

Lutz JA, Carter M, Fields L, Barron S, Littleton JM.

Alcohol Clin Exp Res. 2015 Dec;39(12):2345-53. doi: 10.1111/acer.12896. Epub 2015 Nov 18.

31.

Electrophysiologic features of SYT2 mutations causing a treatable neuromuscular syndrome.

Whittaker RG, Herrmann DN, Bansagi B, Hasan BA, Lofra RM, Logigian EL, Sowden JE, Almodovar JL, Littleton JT, Zuchner S, Horvath R, Lochmüller H.

Neurology. 2015 Dec 1;85(22):1964-71. doi: 10.1212/WNL.0000000000002185. Epub 2015 Oct 30.

32.

Transmission, Development, and Plasticity of Synapses.

Harris KP, Littleton JT.

Genetics. 2015 Oct;201(2):345-75. doi: 10.1534/genetics.115.176529. Review.

33.

Altered relation between lipopolysaccharide-induced inflammatory response and excitotoxicity in rat organotypic hippocampal slice cultures during ethanol withdrawal.

Lutz JA, Carter M, Fields L, Barron S, Littleton JM.

Alcohol Clin Exp Res. 2015 May;39(5):827-35. doi: 10.1111/acer.12705. Epub 2015 Apr 6.

34.

Transmembrane tethering of synaptotagmin to synaptic vesicles controls multiple modes of neurotransmitter release.

Lee J, Littleton JT.

Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):3793-8. doi: 10.1073/pnas.1420312112. Epub 2015 Mar 9.

35.

Fetal Bovine Collagen Matrix in the Treatment of a Full Thickness Burn Wound: A Case Report With Long-Term Follow-Up.

Strong AL, Bennett DK, Spreen EB, Adhvaryu DV, Littleton JC, Mencer EJ.

J Burn Care Res. 2016 May-Jun;37(3):e292-7. doi: 10.1097/BCR.0000000000000221.

36.

Synaptotagmin 2 mutations cause an autosomal-dominant form of lambert-eaton myasthenic syndrome and nonprogressive motor neuropathy.

Herrmann DN, Horvath R, Sowden JE, Gonzalez M, Sanchez-Mejias A, Guan Z, Whittaker RG, Almodovar JL, Lane M, Bansagi B, Pyle A, Boczonadi V, Lochmüller H, Griffin H, Chinnery PF, Lloyd TE, Littleton JT, Zuchner S.

Am J Hum Genet. 2014 Sep 4;95(3):332-9. doi: 10.1016/j.ajhg.2014.08.007. Erratum in: Am J Hum Genet. 2014 Oct 2;95(4):472. Gonzales, Michael [corrected to Gonzalez, Michael].

37.

Synapsin regulates activity-dependent outgrowth of synaptic boutons at the Drosophila neuromuscular junction.

Vasin A, Zueva L, Torrez C, Volfson D, Littleton JT, Bykhovskaia M.

J Neurosci. 2014 Aug 6;34(32):10554-63. doi: 10.1523/JNEUROSCI.5074-13.2014.

38.

Postsynaptic actin regulates active zone spacing and glutamate receptor apposition at the Drosophila neuromuscular junction.

Blunk AD, Akbergenova Y, Cho RW, Lee J, Walldorf U, Xu K, Zhong G, Zhuang X, Littleton JT.

Mol Cell Neurosci. 2014 Jul;61:241-54. doi: 10.1016/j.mcn.2014.07.005. Epub 2014 Jul 24.

39.

Phase 2 study of imexon, a prooxidant molecule, in relapsed and refractory B-cell non-Hodgkin lymphoma.

Barr PM, Miller TP, Friedberg JW, Peterson DR, Baran AM, Herr M, Spier CM, Cui H, Roe DJ, Persky DO, Casulo C, Littleton J, Schwartz M, Puvvada S, Landowski TH, Rimsza LM, Dorr RT, Fisher RI, Bernstein SH, Briehl MM.

Blood. 2014 Aug 21;124(8):1259-65. doi: 10.1182/blood-2014-04-570044. Epub 2014 Jul 11.

40.

Genetic analysis of the Complexin trans-clamping model for cross-linking SNARE complexes in vivo.

Cho RW, Kümmel D, Li F, Baguley SW, Coleman J, Rothman JE, Littleton JT.

Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10317-22. doi: 10.1073/pnas.1409311111. Epub 2014 Jun 30.

41.

A nicotinic receptor-mediated anti-inflammatory effect of the flavonoid rhamnetin in BV2 microglia.

Lutz JA, Kulshrestha M, Rogers DT, Littleton JM.

Fitoterapia. 2014 Oct;98:11-21. doi: 10.1016/j.fitote.2014.06.012. Epub 2014 Jun 24.

42.

Patterns in ritual tooth avulsion at Roonka.

Durband AC, Littleton J, Walshe K.

Am J Phys Anthropol. 2014 Aug;154(4):479-85. doi: 10.1002/ajpa.22531. Epub 2014 May 14.

PMID:
24827419
43.

Retrograde BMP signaling modulates rapid activity-dependent synaptic growth via presynaptic LIM kinase regulation of cofilin.

Piccioli ZD, Littleton JT.

J Neurosci. 2014 Mar 19;34(12):4371-81. doi: 10.1523/JNEUROSCI.4943-13.2014.

44.

Estimating striae of Retzius periodicity nondestructively using partial counts of perikymata.

McFarlane G, Littleton J, Floyd B.

Am J Phys Anthropol. 2014 Jun;154(2):251-8. doi: 10.1002/ajpa.22501. Epub 2014 Feb 28.

PMID:
24578262
45.

Partnerships for health: decimating tuberculosis in the Cook Islands, 1920-1975.

Futter-Puati D, Bryder L, Park J, Littleton J, Herda P.

Health Place. 2014 Jan;25:10-8. doi: 10.1016/j.healthplace.2013.10.006. Epub 2013 Oct 29.

PMID:
24216025
46.

Spontaneous and evoked release are independently regulated at individual active zones.

Melom JE, Akbergenova Y, Gavornik JP, Littleton JT.

J Neurosci. 2013 Oct 30;33(44):17253-63. doi: 10.1523/JNEUROSCI.3334-13.2013.

47.

Modeling Huntington disease in Drosophila: Insights into axonal transport defects and modifiers of toxicity.

Krench M, Littleton JT.

Fly (Austin). 2013 Oct-Dec;7(4):229-36. doi: 10.4161/fly.26279. Epub 2013 Sep 10.

48.

Hunter-gatherer variability: Dental wear in South Australia.

Littleton J, Scott R, McFarlane G, Walshe K.

Am J Phys Anthropol. 2013 Oct;152(2):273-86. doi: 10.1002/ajpa.22358. Epub 2013 Sep 3.

PMID:
23999884
49.

Interaction of the complexin accessory helix with the C-terminus of the SNARE complex: molecular-dynamics model of the fusion clamp.

Bykhovskaia M, Jagota A, Gonzalez A, Vasin A, Littleton JT.

Biophys J. 2013 Aug 6;105(3):679-90. doi: 10.1016/j.bpj.2013.06.018.

50.

Improving the inhibitory activity of arylidenaminoguanidine compounds at the N-methyl-D-aspartate receptor complex from a recursive computational-experimental structure-activity relationship study.

Ring JR, Zheng F, Haubner AJ, Littleton JM, Crooks PA.

Bioorg Med Chem. 2013 Apr 1;21(7):1764-74. doi: 10.1016/j.bmc.2013.01.051. Epub 2013 Jan 31.

PMID:
23465801

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