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Items: 48

1.

A Randomized, Placebo-Controlled, Respiratory Syncytial Virus Human Challenge Study of the Antiviral Efficacy, Safety, and Pharmacokinetics of RV521, an Inhibitor of the RSV-F Protein.

DeVincenzo J, Tait D, Efthimiou J, Mori J, Kim YI, Thomas E, Wilson L, Harland R, Mathews N, Cockerill S, Powell K, Littler E.

Antimicrob Agents Chemother. 2020 Jan 27;64(2). pii: e01884-19. doi: 10.1128/AAC.01884-19. Print 2020 Jan 27.

2.

Clostridium difficile has a single sortase, SrtB, that can be inhibited by small-molecule inhibitors.

Donahue EH, Dawson LF, Valiente E, Firth-Clark S, Major MR, Littler E, Perrior TR, Wren BW.

BMC Microbiol. 2014 Aug 31;14:219. doi: 10.1186/s12866-014-0219-1.

3.

Combinatorial Domain Hunting: solving problems in protein expression.

Littler E.

Drug Discov Today. 2010 Jun;15(11-12):461-7. doi: 10.1016/j.drudis.2010.03.010. Epub 2010 Mar 23. Review.

PMID:
20338258
4.

Clustering of Pseudomonas aeruginosa transcriptomes from planktonic cultures, developing and mature biofilms reveals distinct expression profiles.

Waite RD, Paccanaro A, Papakonstantinopoulou A, Hurst JM, Saqi M, Littler E, Curtis MA.

BMC Genomics. 2006 Jun 26;7:162.

5.

Nucleoside analogs as anti-HBV agents.

Zhou XX, Littler E.

Curr Top Med Chem. 2006;6(9):851-65. Review.

PMID:
16787280
6.
7.

Achievements and challenges in antiviral drug discovery.

Littler E, Oberg B.

Antivir Chem Chemother. 2005;16(3):155-68. Review.

PMID:
16004079
8.

The past, present and future of antiviral drug discovery.

Littler E.

IDrugs. 2004 Dec;7(12):1104-12. Review.

PMID:
15599804
9.

Ganciclovir and penciclovir, but not acyclovir, induce apoptosis in herpes simplex virus thymidine kinase-transformed baby hamster kidney cells.

Shaw MM, Gürr WK, Watts PA, Littler E, Field HJ.

Antivir Chem Chemother. 2001 May;12(3):175-86.

PMID:
12959326
10.

Temporal pattern of herpes simplex virus type 1 infection and cell death in the mouse brain stem: influence of guanosine nucleoside analogues.

Shaw MM, Gürr WK, Thackray AM, Watts PA, Littler E, Field HJ.

J Virol Methods. 2002 Apr;102(1-2):93-102.

PMID:
11879697
11.

Antibodies to Epstein-Barr virus thymidine kinase: a characteristic marker for the serological detection of nasopharyngeal carcinoma.

Connolly Y, Littler E, Sun N, Chen X, Huang PC, Stacey SN, Arrand JR.

Int J Cancer. 2001 Mar 1;91(5):692-7.

12.

Indolocarbazoles: potent, selective inhibitors of human cytomegalovirus replication.

Slater MJ, Cockerill S, Baxter R, Bonser RW, Gohil K, Gowrie C, Robinson JE, Littler E, Parry N, Randall R, Snowden W.

Bioorg Med Chem. 1999 Jun;7(6):1067-74.

PMID:
10428375
13.

Synthesis and anti-herpes virus activity of 2'-deoxy-4'-thiopyrimidine nucleosides.

Rahim SG, Trivedi N, Bogunovic-Batchelor MV, Hardy GW, Mills G, Selway JW, Snowden W, Littler E, Coe PL, Basnak I, Whale RF, Walker RT.

J Med Chem. 1996 Feb 2;39(3):789-95.

PMID:
8576922
14.

The cloning, sequencing and expression of a major antigenic region from the feline calicivirus capsid protein.

Guiver M, Littler E, Caul EO, Fox AJ.

J Gen Virol. 1992 Sep;73 ( Pt 9):2429-33.

PMID:
1402818
15.
16.

32P-postlabelling of alkylated thymidines using Epstein-Barr virus encoded thymidine kinase.

Povey AC, Cooper DP, Littler E.

Carcinogenesis. 1991 Apr;12(4):709-12.

PMID:
1849471
17.

Diagnosis of nasopharyngeal carcinoma by means of recombinant Epstein-Barr virus proteins.

Littler E, Baylis SA, Zeng Y, Conway MJ, Mackett M, Arrand JR.

Lancet. 1991 Mar 23;337(8743):685-9.

PMID:
1672175
19.

Immunological studies on the Epstein-Barr virus encoded alkaline deoxyribonuclease found in virus-producing lymphoblastoid cells.

Baylis SA, Young LS, Purifoy DJ, Littler E.

J Gen Virol. 1991 Feb;72 ( Pt 2):399-404.

PMID:
1847177
20.

Playing an important role.

Littler ER.

Nurs Stand. 1991 Jan 30;5(19):38.

PMID:
27667080
21.

The genome of human herpesvirus 6: maps of unit-length and concatemeric genomes for nine restriction endonucleases.

Martin ME, Thomson BJ, Honess RW, Craxton MA, Gompels UA, Liu MY, Littler E, Arrand JR, Teo I, Jones MD.

J Gen Virol. 1991 Jan;72 ( Pt 1):157-68.

PMID:
1846644
22.
23.

Vectors with multiple insertion sites for expression of cloned genes by T7 RNA polymerase: expression of a peptide from EBV thymidine kinase (TK).

Mackett M, Littler E, Michael R, Gartland M, Arrand JR.

Nucleic Acids Res. 1990 Feb 25;18(4):1082. No abstract available.

24.

Identification, cloning, and expression of the major capsid protein gene of human herpesvirus 6.

Littler E, Lawrence G, Liu MY, Barrell BG, Arrand JR.

J Virol. 1990 Feb;64(2):714-22.

25.

The characterization of the EBV alkaline deoxyribonuclease cloned and expressed in E. coli.

Baylis SA, Purifoy DJ, Littler E.

Nucleic Acids Res. 1989 Oct 11;17(19):7609-22.

26.

Human herpesvirus 6 infection in renal-transplant recipients.

Morris DJ, Littler E, Arrand JR, Jordan D, Mallick NP, Johnson RW.

N Engl J Med. 1989 Jun 8;320(23):1560-1. No abstract available.

PMID:
2542794
28.

Immunological conservation between Epstein-Barr virus and herpes simplex virus.

Littler E, Halliburton IW, Powell KL, Snowden BW, Arrand JR.

J Gen Virol. 1988 Aug;69 ( Pt 8):2021-31.

PMID:
2841414
29.

Identification of an Epstein-Barr virus-coded thymidine kinase.

Littler E, Zeuthen J, McBride AA, Trøst Sørensen E, Powell KL, Walsh-Arrand JE, Arrand JR.

EMBO J. 1986 Aug;5(8):1959-66.

30.

Herpes simplex virus non-structural proteins. III. Function of the major DNA-binding protein.

Littler E, Purifoy D, Minson A, Powell KL.

J Gen Virol. 1983 May;64(Pt 5):983-95.

PMID:
6302216
31.

Antigenic and structural conservation of herpesvirus DNA-binding proteins.

Littler E, Yeo J, Killington RA, Purifoy DJ, Powell KL.

J Gen Virol. 1981 Oct;56(Pt 2):409-19.

PMID:
6171613
32.
33.

Anomalous blood typing from impersonation.

Littler ER, Siverman EM.

JAMA. 1979 Jan 12;241(2):Unknown.

PMID:
102804
34.

Bullet in the left ventricle from a remote gunshot wound to the heart.

Silverman EM, Littler ER.

Chest. 1977 Feb;71(2):234-6.

PMID:
832503
35.

Benign metastasizing uterine leiomyoma. Multiple lymph nodal metastases.

Abell MR, Littler ER.

Cancer. 1975 Dec;36(6):2206-13.

PMID:
1203871
36.

A simple 'Plastazote' splint for the treatment of cervical and high dorsal injuries at the roadside.

Cooke DA, Littler EN, Williams HO.

Practitioner. 1974 Jul;213(1273):65-8. No abstract available.

PMID:
4445083
37.

Gastric leiomyoblastoma in an adolescent.

De Castro FJ, Olsen WR, Littler ER.

Am J Surg. 1972 May;123(5):614-6. No abstract available.

PMID:
5025303
38.

Sebaceous cell lesions of the head and neck.

Batsakis JG, Littler ER, Leahy MS.

Arch Otolaryngol. 1972 Feb;95(2):151-7. No abstract available.

PMID:
5060062
39.
40.

Thyroid carcinoma originating in thyroglossal cyst: report of a case.

Lui AH, Littler ER Jr.

Am Surg. 1970 Sep;36(9):546-8. No abstract available.

PMID:
5457883
41.

Candida parapsilosis septicemia.

Bruns DL, Littler ER, Yanez JE.

Mich Med. 1970 Jul;69(13):585-8. No abstract available.

PMID:
5432514
42.

Skin embolus to lung.

Nosanchuk JS, Littler ER.

Arch Pathol. 1969 May;87(5):542-3. No abstract available.

PMID:
5776892
43.

A trial of ice therapy and exercise in chronic arthritis.

Halliday SM, Littler TR, Littler EN.

Physiotherapy. 1969 Feb;55(2):51-6. No abstract available.

PMID:
5775529
44.

Pseudogranulomatous mastocytic lymphadenitis. A case of systemic mastocytosis with distinctive lymph nodal changes.

Littler ER Jr.

Am J Clin Pathol. 1966 Feb;45(2):180-5. No abstract available.

PMID:
5904721
45.

HEMOLYTIC UREMIC SYNDROME.

MCQUIGGAN MC, OLIVER WJ, LITTLER ER, CERNY JC.

JAMA. 1965 Mar 8;191:787-92. No abstract available.

PMID:
14250062
46.

TERATOMAS OF THE NECK. A CLINICOPATHOLOGIC APPRAISAL.

BATSAKIS JG, LITTLER ER, OBERMAN HA.

Arch Otolaryngol. 1964 Jun;79:619-24. No abstract available.

PMID:
14135081
47.

Asphyxia due to hemangioma in trachea.

LITTLER ER.

J Thorac Cardiovasc Surg. 1963 Apr;45:552-8. No abstract available.

PMID:
13930988
48.

Collagen diseases.

LITTLER ER.

McGill Med J. 1958 Feb;27(1):32-44. No abstract available.

PMID:
13515573

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