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Items: 41

1.

Protease-associated import systems are widespread in Gram-negative bacteria.

Grinter R, Leung PM, Wijeyewickrema LC, Littler D, Beckham S, Pike RN, Walker D, Greening C, Lithgow T.

PLoS Genet. 2019 Oct 15;15(10):e1008435. doi: 10.1371/journal.pgen.1008435. eCollection 2019 Oct.

2.

FusC, a member of the M16 protease family acquired by bacteria for iron piracy against plants.

Grinter R, Hay ID, Song J, Wang J, Teng D, Dhanesakaran V, Wilksch JJ, Davies MR, Littler D, Beckham SA, Henderson IR, Strugnell RA, Dougan G, Lithgow T.

PLoS Biol. 2018 Aug 2;16(8):e2006026. doi: 10.1371/journal.pbio.2006026. eCollection 2018 Aug.

3.

Structure-function analyses of a pertussis-like toxin from pathogenic Escherichia coli reveal a distinct mechanism of inhibition of trimeric G-proteins.

Littler DR, Ang SY, Moriel DG, Kocan M, Kleifeld O, Johnson MD, Tran MT, Paton AW, Paton JC, Summers RJ, Schembri MA, Rossjohn J, Beddoe T.

J Biol Chem. 2017 Sep 8;292(36):15143-15158. doi: 10.1074/jbc.M117.796094. Epub 2017 Jun 29.

4.

Crystal structure of fuculose aldolase from the Antarctic psychrophilic yeast Glaciozyma antarctica PI12.

Jaafar NR, Littler D, Beddoe T, Rossjohn J, Illias RM, Mahadi NM, Mackeen MM, Murad AM, Abu Bakar FD.

Acta Crystallogr F Struct Biol Commun. 2016 Nov 1;72(Pt 11):831-839. Epub 2016 Oct 27.

5.

Disrupting the Allosteric Interaction between the Plasmodium falciparum cAMP-dependent Kinase and Its Regulatory Subunit.

Littler DR, Bullen HE, Harvey KL, Beddoe T, Crabb BS, Rossjohn J, Gilson PR.

J Biol Chem. 2016 Dec 2;291(49):25375-25386. Epub 2016 Oct 13.

6.

Antimalarial activity of novel 4-cyano-3-methylisoquinoline inhibitors against Plasmodium falciparum: design, synthesis and biological evaluation.

Buskes MJ, Harvey KL, Richards BJ, Kalhor R, Christoff RM, Gardhi CK, Littler DR, Cope ED, Prinz B, Weiss GE, O'Brien NJ, Crabb BS, Deady LW, Gilson PR, Abbott BM.

Org Biomol Chem. 2016 May 18;14(20):4617-39. doi: 10.1039/c5ob02517f.

PMID:
27105169
7.

Cloning, expression, purification and crystallographic studies of galectin-11 from domestic sheep (Ovis aries).

Sakthivel D, Littler D, Shahine A, Troy S, Johnson M, Rossjohn J, Piedrafita D, Beddoe T.

Acta Crystallogr F Struct Biol Commun. 2015 Aug;71(Pt 8):993-7. doi: 10.1107/S2053230X15010195. Epub 2015 Jul 28.

8.

A structural and functional investigation of a novel protein from Mycobacterium smegmatis implicated in mycobacterial macrophage survivability.

Shahine A, Littler D, Brammananath R, Chan PY, Crellin PK, Coppel RL, Rossjohn J, Beddoe T.

Acta Crystallogr D Biol Crystallogr. 2014 Sep;70(Pt 9):2264-76. doi: 10.1107/S139900471401092X. Epub 2014 Aug 23.

PMID:
25195741
9.

The structure of the cytomegalovirus-encoded m04 glycoprotein, a prototypical member of the m02 family of immunoevasins.

Berry R, Vivian JP, Deuss FA, Balaji GR, Saunders PM, Lin J, Littler DR, Brooks AG, Rossjohn J.

J Biol Chem. 2014 Aug 22;289(34):23753-63. doi: 10.1074/jbc.M114.584128. Epub 2014 Jun 30.

10.

EcxAB is a founding member of a new family of metalloprotease AB5 toxins with a hybrid cholera-like B subunit.

Ng NM, Littler DR, Paton AW, Le Nours J, Rossjohn J, Paton JC, Beddoe T.

Structure. 2013 Nov 5;21(11):2003-13. doi: 10.1016/j.str.2013.08.024. Epub 2013 Oct 3.

11.

Cloning, expression, purification and preliminary X-ray diffraction studies of a novel AB₅ toxin.

Ng N, Littler D, Le Nours J, Paton AW, Paton JC, Rossjohn J, Beddoe T.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Aug;69(Pt 8):912-5. doi: 10.1107/S1744309113018927. Epub 2013 Jul 27.

12.

Cloning, expression, purification and preliminary X-ray diffraction studies of a mycobacterial protein implicated in bacterial survival in macrophages.

Shahine AE, Chan PY, Littler D, Vivian J, Brammananth R, Crellin PK, Coppel RL, Rossjohn J, Beddoe T.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 May 1;69(Pt 5):566-9. doi: 10.1107/S1744309113010427. Epub 2013 Apr 30.

13.

A TPR domain-containing N-terminal module of MPS1 is required for its kinetochore localization by Aurora B.

Nijenhuis W, von Castelmur E, Littler D, De Marco V, Tromer E, Vleugel M, van Osch MH, Snel B, Perrakis A, Kops GJ.

J Cell Biol. 2013 Apr 15;201(2):217-31. doi: 10.1083/jcb.201210033. Epub 2013 Apr 8.

14.

BLOOM OF THE GIANT ANADYOMENE GIGANTODICTYON SP. NOV. (ANADYOMENACEAE, CLADOPHORALES) FROM THE OUTER SLOPE (25-50 m) OF THE BELIZE BARRIER REEF(1).

Littler MM, Littler DS.

J Phycol. 2012 Feb;48(1):60-3. doi: 10.1111/j.1529-8817.2011.01108.x. Epub 2012 Jan 10.

PMID:
27009650
15.

Enabling high-throughput ligation-independent cloning and protein expression for the family of ubiquitin specific proteases.

Luna-Vargas MP, Christodoulou E, Alfieri A, van Dijk WJ, Stadnik M, Hibbert RG, Sahtoe DD, Clerici M, Marco VD, Littler D, Celie PH, Sixma TK, Perrakis A.

J Struct Biol. 2011 Aug;175(2):113-9. doi: 10.1016/j.jsb.2011.03.017. Epub 2011 Mar 29.

PMID:
21453775
16.

The structural basis for recognition of base J containing DNA by a novel DNA binding domain in JBP1.

Heidebrecht T, Christodoulou E, Chalmers MJ, Jan S, Ter Riet B, Grover RK, Joosten RP, Littler D, van Luenen H, Griffin PR, Wentworth P Jr, Borst P, Perrakis A.

Nucleic Acids Res. 2011 Jul;39(13):5715-28. doi: 10.1093/nar/gkr125. Epub 2011 Mar 16.

17.

Molecular basis of cytokine receptor activation.

Lopez AF, Hercus TR, Ekert P, Littler DR, Guthridge M, Thomas D, Ramshaw HS, Stomski F, Perugini M, D'Andrea R, Grimbaldeston M, Parker MW.

IUBMB Life. 2010 Jul;62(7):509-18. doi: 10.1002/iub.350. Review.

18.

Metamorphic response of the CLIC1 chloride intracellular ion channel protein upon membrane interaction.

Goodchild SC, Howell MW, Littler DR, Mandyam RA, Sale KL, Mazzanti M, Breit SN, Curmi PM, Brown LJ.

Biochemistry. 2010 Jun 29;49(25):5278-89. doi: 10.1021/bi100111c.

PMID:
20507120
19.

Marine macroalgal diversity assessment of Saba Bank, Netherlands Antilles.

Littler MM, Littler DS, Brooks BL.

PLoS One. 2010 May 21;5(5):e10677. doi: 10.1371/journal.pone.0010677.

20.

Structure of the FoxM1 DNA-recognition domain bound to a promoter sequence.

Littler DR, Alvarez-Fernández M, Stein A, Hibbert RG, Heidebrecht T, Aloy P, Medema RH, Perrakis A.

Nucleic Acids Res. 2010 Jul;38(13):4527-38. doi: 10.1093/nar/gkq194. Epub 2010 Mar 31.

21.

Structure of human CLIC3 at 2 A resolution.

Littler DR, Brown LJ, Breit SN, Perrakis A, Curmi PM.

Proteins. 2010 May 1;78(6):1594-600. doi: 10.1002/prot.22675. No abstract available.

PMID:
20146363
22.

A conserved mechanism of autoinhibition for the AMPK kinase domain: ATP-binding site and catalytic loop refolding as a means of regulation.

Littler DR, Walker JR, Davis T, Wybenga-Groot LE, Finerty PJ Jr, Newman E, Mackenzie F, Dhe-Paganon S.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Feb 1;66(Pt 2):143-51. doi: 10.1107/S1744309109052543. Epub 2010 Jan 27.

23.

The enigma of the CLIC proteins: Ion channels, redox proteins, enzymes, scaffolding proteins?

Littler DR, Harrop SJ, Goodchild SC, Phang JM, Mynott AV, Jiang L, Valenzuela SM, Mazzanti M, Brown LJ, Breit SN, Curmi PM.

FEBS Lett. 2010 May 17;584(10):2093-101. doi: 10.1016/j.febslet.2010.01.027. Epub 2010 Jan 19. Review.

24.

Spatiotemporal regulation of chloride intracellular channel protein CLIC4 by RhoA.

Ponsioen B, van Zeijl L, Langeslag M, Berryman M, Littler D, Jalink K, Moolenaar WH.

Mol Biol Cell. 2009 Nov;20(22):4664-72. doi: 10.1091/mbc.E09-06-0529. Epub 2009 Sep 23.

25.

Oxidation promotes insertion of the CLIC1 chloride intracellular channel into the membrane.

Goodchild SC, Howell MW, Cordina NM, Littler DR, Breit SN, Curmi PM, Brown LJ.

Eur Biophys J. 2009 Dec;39(1):129-38. doi: 10.1007/s00249-009-0450-0. Epub 2009 Apr 23.

PMID:
19387633
26.

A multi-locus time-calibrated phylogeny of the siphonous green algae.

Verbruggen H, Ashworth M, LoDuca ST, Vlaeminck C, Cocquyt E, Sauvage T, Zechman FW, Littler DS, Littler MM, Leliaert F, De Clerck O.

Mol Phylogenet Evol. 2009 Mar;50(3):642-53. doi: 10.1016/j.ympev.2008.12.018. Epub 2008 Dec 25.

PMID:
19141323
27.

Polo-box domains confer target specificity to the Polo-like kinase family.

van de Weerdt BC, Littler DR, Klompmaker R, Huseinovic A, Fish A, Perrakis A, Medema RH.

Biochim Biophys Acta. 2008 Jun;1783(6):1015-22. doi: 10.1016/j.bbamcr.2008.02.019. Epub 2008 Mar 5.

28.

Comparison of vertebrate and invertebrate CLIC proteins: the crystal structures of Caenorhabditis elegans EXC-4 and Drosophila melanogaster DmCLIC.

Littler DR, Harrop SJ, Brown LJ, Pankhurst GJ, Mynott AV, Luciani P, Mandyam RA, Mazzanti M, Tanda S, Berryman MA, Breit SN, Curmi PM.

Proteins. 2008 Apr;71(1):364-78.

PMID:
17985355
29.

Structure of the Janus protein human CLIC2.

Cromer BA, Gorman MA, Hansen G, Adams JJ, Coggan M, Littler DR, Brown LJ, Mazzanti M, Breit SN, Curmi PM, Dulhunty AF, Board PG, Parker MW.

J Mol Biol. 2007 Nov 30;374(3):719-31. Epub 2007 Sep 20.

PMID:
17945253
30.

Species boundaries and phylogenetic relationships within the green algal genus Codium (Bryopsidales) based on plastid DNA sequences.

Verbruggen H, Leliaert F, Maggs CA, Shimada S, Schils T, Provan J, Booth D, Murphy S, De Clerck O, Littler DS, Littler MM, Coppejans E.

Mol Phylogenet Evol. 2007 Jul;44(1):240-54. Epub 2007 Jan 31.

PMID:
17346993
31.

Structure of human protein kinase C eta (PKCeta) C2 domain and identification of phosphorylation sites.

Littler DR, Walker JR, She YM, Finerty PJ Jr, Newman EM, Dhe-Paganon S.

Biochem Biophys Res Commun. 2006 Nov 3;349(4):1182-9. Epub 2006 Sep 5.

PMID:
16973127
32.

Crystal structure of the soluble form of the redox-regulated chloride ion channel protein CLIC4.

Littler DR, Assaad NN, Harrop SJ, Brown LJ, Pankhurst GJ, Luciani P, Aguilar MI, Mazzanti M, Berryman MA, Breit SN, Curmi PM.

FEBS J. 2005 Oct;272(19):4996-5007.

33.

The intracellular chloride ion channel protein CLIC1 undergoes a redox-controlled structural transition.

Littler DR, Harrop SJ, Fairlie WD, Brown LJ, Pankhurst GJ, Pankhurst S, DeMaere MZ, Campbell TJ, Bauskin AR, Tonini R, Mazzanti M, Breit SN, Curmi PM.

J Biol Chem. 2004 Mar 5;279(10):9298-305. Epub 2003 Nov 12.

34.

In vivo protein cyclization promoted by a circularly permuted Synechocystis sp. PCC6803 DnaB mini-intein.

Williams NK, Prosselkov P, Liepinsh E, Line I, Sharipo A, Littler DR, Curmi PM, Otting G, Dixon NE.

J Biol Chem. 2002 Mar 8;277(10):7790-8. Epub 2001 Dec 12.

35.

Impact of CLOD Pathogen on Pacific Coral Reefs.

Littler MM, Littler DS.

Science. 1995 Mar 3;267(5202):1356-60.

PMID:
17812612
36.

Complex interactions in the control of coral zonation on a Caribbean reef flat.

Littler MM, Taylor PR, Littler DS.

Oecologia. 1989 Aug;80(3):331-340. doi: 10.1007/BF00379034.

PMID:
28312060
37.

Evidence for chemical defense in tropical green algaCaulerpa ashmeadii (Caulerpaceae: Chlorophyta): Isolation of new bioactive sesquiterpenoids.

Paul VJ, Littler MM, Littler DS, Fenical W.

J Chem Ecol. 1987 May;13(5):1171-85. doi: 10.1007/BF01020547.

PMID:
24302141
38.

Escapes from herbivory in relation to the structure of mangrove island macroalgal communities.

Taylor PR, Littler MM, Littler DS.

Oecologia. 1986 Jul;69(4):481-490. doi: 10.1007/BF00410352.

PMID:
28311605
39.

Deepest known plant life discovered on an uncharted seamount.

Littler MM, Littler DS, Blair SM, Norris JN.

Science. 1985 Jan 4;227(4682):57-9.

PMID:
17810025
40.

The sites of the systemic insecticidal action of sulphaquinoxaline.

Venters D, Littler DA.

Trans R Soc Trop Med Hyg. 1972;66(1):25-6. No abstract available.

PMID:
4403088
41.

Gleep: design, construction, and use.

COLMER FC, LITTLER DJ.

Nucleonics. 1951 Jan;8(1):3-12. No abstract available.

PMID:
14807092

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