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Meta-analysis of the Cepheid Xpert® CT/NG assay for extragenital detection of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infections.

Bristow CC, Morris SR, Little SJ, Mehta SR, Klausner JD.

Sex Health. 2019 Jul 12. doi: 10.1071/SH18079. [Epub ahead of print]


Salvage Antiretroviral Therapy: Time for "DeNUKElearization"?

Hoenigl M, Little SJ.

J Infect Dis. 2019 May 28. pii: jiz283. doi: 10.1093/infdis/jiz283. [Epub ahead of print] No abstract available.


Trust and Expectations of Researchers and Public Health Departments for the Use of HIV Molecular Epidemiology.

Schairer CE, Mehta SR, Vinterbo SA, Hoenigl M, Kalichman M, Little SJ.

AJOB Empir Bioeth. 2019 Jul-Sep;10(3):201-213. doi: 10.1080/23294515.2019.1601648. Epub 2019 May 3.


Primary Incidence of Hepatitis C Virus Infection Among HIV-Infected Men Who Have Sex With Men in San Diego, 2000-2015.

Chaillon A, Sun X, Cachay ER, Looney D, Wyles D, Garfein RS, Martin TCS, Jain S, Mehta SR, Smith DM, Little SJ, Martin NK.

Open Forum Infect Dis. 2019 Apr 3;6(4):ofz160. doi: 10.1093/ofid/ofz160. eCollection 2019 Apr.


Genetic network analysis to assess the risk of HIV transmission among MSM seeking partners on the Internet.

Martin TCS, Chaillon A, Graves SK, Lin T, Gianella S, Smith DM, Little SJ, Hoenigl M.

Clin Infect Dis. 2019 Apr 6. pii: ciz278. doi: 10.1093/cid/ciz278. [Epub ahead of print]


Attitudes and Preferences Regarding the Use of Rapid Self-Testing for Sexually Transmitted Infections and HIV in San Diego Area Men Who Have Sex With Men.

Cushman TA, Graves SK, Little SJ.

Open Forum Infect Dis. 2019 Mar 11;6(3):ofz043. doi: 10.1093/ofid/ofz043. eCollection 2019 Mar.


The inhibitor apoptosis protein antagonist Debio 1143 Is an attractive HIV-1 latency reversal candidate.

Bobardt M, Kuo J, Chatterji U, Chanda S, Little SJ, Wiedemann N, Vuagniaux G, Gallay PA.

PLoS One. 2019 Feb 4;14(2):e0211746. doi: 10.1371/journal.pone.0211746. eCollection 2019.


Ethical considerations for HIV cure-related research at the end of life.

Dubé K, Gianella S, Concha-Garcia S, Little SJ, Kaytes A, Taylor J, Mathur K, Javadi S, Nathan A, Patel H, Luter S, Philpott-Jones S, Brown B, Smith D.

BMC Med Ethics. 2018 Oct 20;19(1):83. doi: 10.1186/s12910-018-0321-2.


The Control of HIV After Antiretroviral Medication Pause (CHAMP) Study: Posttreatment Controllers Identified From 14 Clinical Studies.

Namazi G, Fajnzylber JM, Aga E, Bosch RJ, Acosta EP, Sharaf R, Hartogensis W, Jacobson JM, Connick E, Volberding P, Skiest D, Margolis D, Sneller MC, Little SJ, Gianella S, Smith DM, Kuritzkes DR, Gulick RM, Mellors JW, Mehraj V, Gandhi RT, Mitsuyasu R, Schooley RT, Henry K, Tebas P, Deeks SG, Chun TW, Collier AC, Routy JP, Hecht FM, Walker BD, Li JZ.

J Infect Dis. 2018 Nov 5;218(12):1954-1963. doi: 10.1093/infdis/jiy479.


A Simple Symptom Score for Acute Human Immunodeficiency Virus Infection in a San Diego Community-Based Screening Program.

Lin TC, Gianella S, Tenenbaum T, Little SJ, Hoenigl M.

Clin Infect Dis. 2018 Jun 18;67(1):105-111. doi: 10.1093/cid/cix1130.


Temporal variation in HIV-specific IgG subclass antibodies during acute infection differentiates spontaneous controllers from chronic progressors.

Sadanand S, Das J, Chung AW, Schoen MK, Lane S, Suscovich TJ, Streeck H, Smith DM, Little SJ, Lauffenburger DA, Richman DD, Alter G.

AIDS. 2018 Feb 20;32(4):443-450. doi: 10.1097/QAD.0000000000001716.


Size, Composition, and Evolution of HIV DNA Populations during Early Antiretroviral Therapy and Intensification with Maraviroc.

Chaillon A, Gianella S, Lada SM, Perez-Santiago J, Jordan P, Ignacio C, Karris M, Richman DD, Mehta SR, Little SJ, Wertheim JO, Smith DM.

J Virol. 2018 Jan 17;92(3). pii: e01589-17. doi: 10.1128/JVI.01589-17. Print 2018 Feb 1.


Infection Staging and Incidence Surveillance Applications of High Dynamic Range Diagnostic Immuno-Assay Platforms.

Grebe E, Welte A, Hall J, Keating SM, Facente SN, Marson K, Martin JN, Little SJ, Price MA, Kallas EG, Busch MP, Pilcher CD, Murphy G.

J Acquir Immune Defic Syndr. 2017 Dec 15;76(5):547-555. doi: 10.1097/QAI.0000000000001537.


No Substantial Evidence for Sexual Transmission of Minority HIV Drug Resistance Mutations in Men Who Have Sex with Men.

Chaillon A, Nakazawa M, Wertheim JO, Little SJ, Smith DM, Mehta SR, Gianella S.

J Virol. 2017 Oct 13;91(21). pii: e00769-17. doi: 10.1128/JVI.00769-17. Print 2017 Nov 1.


Sexual Partner Concurrency Among Partners Reported by MSM with Recent HIV Infection.

Pines HA, Karris MY, Little SJ.

AIDS Behav. 2017 Oct;21(10):3026-3034. doi: 10.1007/s10461-017-1855-x.


Dietary nitrate supplementation increases acute mountain sickness severity and sense of effort during hypoxic exercise.

Rossetti GMK, Macdonald JH, Wylie LJ, Little SJ, Newton V, Wood B, Hawkins KA, Beddoe R, Davies HE, Oliver SJ.

J Appl Physiol (1985). 2017 Oct 1;123(4):983-992. doi: 10.1152/japplphysiol.00293.2017. Epub 2017 Jul 6.


Intrasubtype B HIV-1 Superinfection Correlates with Delayed Neutralizing Antibody Response.

Wagner GA, Landais E, Caballero G, Phung P, Kosakovsky Pond SL, Poignard P, Richman DD, Little SJ, Smith DM.

J Virol. 2017 Aug 10;91(17). pii: e00475-17. doi: 10.1128/JVI.00475-17. Print 2017 Sep 1.


Increased HIV-1 superinfection risk in carriers of specific human leukocyte antigen alleles.

Vesa J, Chaillon A, Wagner GA, Anderson CM, Richman DD, Smith DM, Little SJ.

AIDS. 2017 May 15;31(8):1149-1158. doi: 10.1097/QAD.0000000000001445.


Evaluation of the Predictive Potential of the Short Acute Retroviral Syndrome Severity Score for HIV-1 Disease Progression in Individuals With Acute HIV Infection.

Hoenigl M, Braun DL, Kouyos R, Günthard HF, Little SJ.

J Acquir Immune Defic Syndr. 2017 Apr 1;74(4):e114-e117. doi: 10.1097/QAI.0000000000001263. No abstract available.


Longitudinal Viral Dynamics in Semen During Early HIV Infection.

Morris SR, Zhao M, Smith DM, Vargas MV, Little SJ, Gianella S.

Clin Infect Dis. 2017 Feb 15;64(4):428-434. doi: 10.1093/cid/ciw784.


Risk profile and HIV testing outcomes of women undergoing community-based testing in San Diego 2008-2014.

Graves SK, Little SJ, Hoenigl M.

Sci Rep. 2017 Feb 6;7:42183. doi: 10.1038/srep42183.


Evaluation of opt-out inpatient HIV screening at an urban teaching hospital.

Osorio G, Hoenigl M, Quartarolo J, Barger K, Morris SR, Reed SL, Lee J, Little SJ.

AIDS Care. 2017 Aug;29(8):1014-1018. doi: 10.1080/09540121.2017.1282106. Epub 2017 Jan 23.


Early Antiretroviral Therapy Is Associated with Lower HIV DNA Molecular Diversity and Lower Inflammation in Cerebrospinal Fluid but Does Not Prevent the Establishment of Compartmentalized HIV DNA Populations.

Oliveira MF, Chaillon A, Nakazawa M, Vargas M, Letendre SL, Strain MC, Ellis RJ, Morris S, Little SJ, Smith DM, Gianella S.

PLoS Pathog. 2017 Jan 3;13(1):e1006112. doi: 10.1371/journal.ppat.1006112. eCollection 2017 Jan.


Partner services in adults with acute and early HIV infection.

Green N, Hoenigl M, Chaillon A, Anderson CM, Kosakovsky Pond SL, Smith DM, Little SJ.

AIDS. 2017 Jan 14;31(2):287-293. doi: 10.1097/QAD.0000000000001308.


Can research at the end of life be a useful tool to advance HIV cure?

Gianella S, Taylor J, Brown TR, Kaytes A, Achim CL, Moore DJ, Little SJ, Ellis RJ, Smith DM.

AIDS. 2017 Jan 2;31(1):1-4. No abstract available.


Concurrency and HIV transmission network characteristics among MSM with recent HIV infection.

Pines HA, Wertheim JO, Liu L, Garfein RS, Little SJ, Karris MY.

AIDS. 2016 Nov 28;30(18):2875-2883.


Asymptomatic CMV Replication During Early Human Immunodeficiency Virus (HIV) Infection Is Associated With Lower CD4/CD8 Ratio During HIV Treatment.

Smith DM, Nakazawa M, Freeman ML, Anderson CM, Oliveira MF, Little SJ, Gianella S.

Clin Infect Dis. 2016 Dec 1;63(11):1517-1524. Epub 2016 Sep 6.


Rapid HIV Viral Load Suppression in those Initiating Antiretroviral Therapy at First Visit after HIV Diagnosis.

Hoenigl M, Chaillon A, Moore DJ, Morris SR, Mehta SR, Gianella S, Amico KR, Little SJ.

Sci Rep. 2016 Sep 6;6:32947. doi: 10.1038/srep32947.


How can we detect HIV during the acute or primary stage of infection?

Hoenigl M, Little SJ.

Expert Rev Mol Diagn. 2016 Oct;16(10):1049-1051. Epub 2016 Aug 30. No abstract available.


Validation of the GeneXpert® CT/NG Assay for use with Male Pharyngeal and Rectal Swabs.

Geiger R, Smith DM, Little SJ, Mehta SR.

Austin J HIV AIDS Res. 2016;3(1). pii: 1021. Epub 2016 Mar 1.


Screening for acute HIV infection in community-based settings: Cost-effectiveness and impact on transmissions.

Hoenigl M, Chaillon A, Mehta SR, Smith DM, Graff-Zivin J, Little SJ.

J Infect. 2016 Nov;73(5):476-484. doi: 10.1016/j.jinf.2016.07.019. Epub 2016 Aug 11.


RETRACTED: Investigation of the GeneXpert® CT/NG assay for use with male pharyngeal and rectal swabs.

Geiger R, Smith DM, Little SJ, Mehta SR.

Int J STD AIDS. 2016 Jan 1:956462416665059. doi: 10.1177/0956462416665059. [Epub ahead of print] No abstract available. Retraction in: Int J STD AIDS. 2017 Jan 1;:956462416688430.


Viral load criteria and threshold optimization to improve HIV incidence assay characteristics.

Kassanjee R, Pilcher CD, Busch MP, Murphy G, Facente SN, Keating SM, Mckinney E, Marson K, Price MA, Martin JN, Little SJ, Hecht FM, Kallas EG, Welte A; Consortium for the Evaluation and Performance of HIV Incidence Assays (CEPHIA).

AIDS. 2016 Sep 24;30(15):2361-71. doi: 10.1097/QAD.0000000000001209.


A practical online tool to estimate antiretroviral coverage for HIV infected and susceptible populations needed to reduce local HIV epidemics.

Chaillon A, Hoenigl M, Mehta SR, Weibel N, Little SJ, Smith DM.

Sci Rep. 2016 Jun 24;6:28707. doi: 10.1038/srep28707.


Characterizing the multiplicity of HIV founder variants during sexual transmission among MSM.

Chaillon A, Gianella S, Little SJ, Caballero G, Barin F, Kosakovsky Pond S, Richman DD, Smith DM, Mehta SR.

Virus Evol. 2016 Jun 8;2(1):vew012. doi: 10.1093/ve/vew012. eCollection 2016 Jan.


HIV Infection Rates and Risk Behavior among Young Men undergoing community-based Testing in San Diego.

Hoenigl M, Chaillon A, Morris SR, Little SJ.

Sci Rep. 2016 May 16;6:25927. doi: 10.1038/srep25927.


Using HIV Sequence and Epidemiologic Data to Assess the Effect of Self-referral Testing for Acute HIV Infection on Incident Diagnoses in San Diego, California.

Mehta SR, Murrell B, Anderson CM, Kosakovsky Pond SL, Wertheim JO, Young JA, Freitas L, Richman DD, Mathews WC, Scheffler K, Little SJ, Smith DM.

Clin Infect Dis. 2016 Jul 1;63(1):101-107. doi: 10.1093/cid/ciw161. Epub 2016 May 11.


CD4/CD8 Cell Ratio in Acute HIV Infection and the Impact of Early Antiretroviral Therapy.

Hoenigl M, Chaillon A, Little SJ.

Clin Infect Dis. 2016 Aug 1;63(3):425-6. doi: 10.1093/cid/ciw293. Epub 2016 May 3. No abstract available.


Neurobehavioral Disturbances During Acute and Early HIV Infection.

Kamat R, Doyle KL, Iudicello JE, Morgan EE, Morris S, Smith DM, Little SJ, Grant I, Woods SP; Translational Methamphetamine AIDS Research Center (TMARC) Group.

Cogn Behav Neurol. 2016 Mar;29(1):1-10. doi: 10.1097/WNN.0000000000000084.


Characterization of HIV Transmission in South-East Austria.

Hoenigl M, Chaillon A, Kessler HH, Haas B, Stelzl E, Weninger K, Little SJ, Mehta SR.

PLoS One. 2016 Mar 11;11(3):e0151478. doi: 10.1371/journal.pone.0151478. eCollection 2016.


Colorectal Disorders in Acute Human Immunodeficiency Virus Infection: A Case Series.

Panichsillapakit T, Patel D, Santangelo J, Richman DD, Little SJ, Smith DM.

Open Forum Infect Dis. 2016 Jan 29;3(1):ofw014. doi: 10.1093/ofid/ofw014. eCollection 2016 Jan.


Signs or Symptoms of Acute HIV Infection in a Cohort Undergoing Community-Based Screening.

Hoenigl M, Green N, Camacho M, Gianella S, Mehta SR, Smith DM, Little SJ.

Emerg Infect Dis. 2016 Mar;22(3):532-4. doi: 10.3201/eid2203.151607.


Replication of Human Herpesviruses Is Associated with Higher HIV DNA Levels during Antiretroviral Therapy Started at Early Phases of HIV Infection.

Gianella S, Anderson CM, Var SR, Oliveira MF, Lada SM, Vargas MV, Massanella M, Little SJ, Richman DD, Strain MC, Pérez-Santiago J, Smith DM.

J Virol. 2016 Mar 28;90(8):3944-3952. doi: 10.1128/JVI.02638-15. Print 2016 Apr.


HIV Transmission Networks in the San Diego-Tijuana Border Region.

Mehta SR, Wertheim JO, Brouwer KC, Wagner KD, Chaillon A, Strathdee S, Patterson TL, Rangel MG, Vargas M, Murrell B, Garfein R, Little SJ, Smith DM.

EBioMedicine. 2015 Jul 18;2(10):1456-63. doi: 10.1016/j.ebiom.2015.07.024. eCollection 2015 Oct.


Distinct cytokine/chemokine network in semen and blood characterize different stages of HIV infection.

Vanpouille C, Introini A, Morris SR, Margolis L, Daar ES, Dube MP, Little SJ, Smith DM, Lisco A, Gianella S.

AIDS. 2016 Jan;30(2):193-201. doi: 10.1097/QAD.0000000000000964.


No evidence of posttreatment control after early initiation of antiretroviral therapy.

Gianella S, Anderson CM, Richman DD, Smith DM, Little SJ.

AIDS. 2015 Oct 23;29(16):2093-7. doi: 10.1097/QAD.0000000000000816.


Clear Links Between Starting Methamphetamine and Increasing Sexual Risk Behavior: A Cohort Study Among Men Who Have Sex With Men.

Hoenigl M, Chaillon A, Moore DJ, Morris SR, Smith DM, Little SJ.

J Acquir Immune Defic Syndr. 2016 Apr 15;71(5):551-7. doi: 10.1097/QAI.0000000000000888.


Costs per Diagnosis of Acute HIV Infection in Community-based Screening Strategies: A Comparative Analysis of Four Screening Algorithms.

Hoenigl M, Graff-Zivin J, Little SJ.

Clin Infect Dis. 2016 Feb 15;62(4):501-511. doi: 10.1093/cid/civ912. Epub 2015 Oct 27.


Risk Behavior and Sexually Transmitted Infections Among Transgender Women and Men Undergoing Community-Based Screening for Acute and Early HIV Infection in San Diego.

Green N, Hoenigl M, Morris S, Little SJ.

Medicine (Baltimore). 2015 Oct;94(41):e1830. doi: 10.1097/MD.0000000000001830.

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