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Items: 1 to 50 of 85

1.

Chromatin targeting of nuclear pore proteins induces chromatin decondensation.

Kuhn TM, Pascual-Garcia P, Gozalo A, Little SC, Capelson M.

J Cell Biol. 2019 Sep 2;218(9):2945-2961. doi: 10.1083/jcb.201807139. Epub 2019 Jul 31.

PMID:
31366666
2.

Spatiotemporal Patterning of Zygotic Genome Activation in a Model Vertebrate Embryo.

Chen H, Einstein LC, Little SC, Good MC.

Dev Cell. 2019 Jun 17;49(6):852-866.e7. doi: 10.1016/j.devcel.2019.05.036.

PMID:
31211992
3.

Oncogenic Notch Promotes Long-Range Regulatory Interactions within Hyperconnected 3D Cliques.

Petrovic J, Zhou Y, Fasolino M, Goldman N, Schwartz GW, Mumbach MR, Nguyen SC, Rome KS, Sela Y, Zapataro Z, Blacklow SC, Kruhlak MJ, Shi J, Aster JC, Joyce EF, Little SC, Vahedi G, Pear WS, Faryabi RB.

Mol Cell. 2019 Mar 21;73(6):1174-1190.e12. doi: 10.1016/j.molcel.2019.01.006. Epub 2019 Feb 7.

PMID:
30745086
4.

Novel Mechanistic Roles for Ankyrin-G in Cardiac Remodeling and Heart Failure.

Makara MA, Curran J, Lubbers ER, Murphy NP, Little SC, Musa H, Smith SA, Unudurthi SD, Rajaram MVS, Janssen PML, Boyden PA, Bradley EA, Hund TJ, Mohler PJ.

JACC Basic Transl Sci. 2018 Nov 12;3(5):675-689. doi: 10.1016/j.jacbts.2018.07.008. eCollection 2018 Oct.

5.

Diverse Spatial Expression Patterns Emerge from Unified Kinetics of Transcriptional Bursting.

Zoller B, Little SC, Gregor T.

Cell. 2018 Oct 18;175(3):835-847.e25. doi: 10.1016/j.cell.2018.09.056.

6.

Gastro-oesophageal fistula in an achalasia patient following myotomy as an unusual cause of heartburn.

Falk GL, Little SC.

Ann R Coll Surg Engl. 2019 Feb;101(2):e35-e37. doi: 10.1308/rcsann.2018.0179. Epub 2018 Oct 5.

PMID:
30286658
7.

NF-κB inhibition rescues cardiac function by remodeling calcium genes in a Duchenne muscular dystrophy model.

Peterson JM, Wang DJ, Shettigar V, Roof SR, Canan BD, Bakkar N, Shintaku J, Gu JM, Little SC, Ratnam NM, Londhe P, Lu L, Gaw CE, Petrosino JM, Liyanarachchi S, Wang H, Janssen PML, Davis JP, Ziolo MT, Sharma SM, Guttridge DC.

Nat Commun. 2018 Aug 24;9(1):3431. doi: 10.1038/s41467-018-05910-1.

8.

Pneumothorax: Laparoscopic Intraoperative Management During Fundoplication Facilitates Management of Cardiopulmonary Instability and Surgical Exposure.

Falk GL, D'Netto TJ, Phillips S, Little SC.

J Laparoendosc Adv Surg Tech A. 2018 Nov;28(11):1371-1373. doi: 10.1089/lap.2018.0050. Epub 2018 Jun 29.

PMID:
29958063
9.

Single mRNA Molecule Detection in Drosophila.

Little SC, Gregor T.

Methods Mol Biol. 2018;1649:127-142. doi: 10.1007/978-1-4939-7213-5_8.

10.

Dramatic elevation in urinary amino terminal titin fragment excretion quantified by immunoassay in Duchenne muscular dystrophy patients and in dystrophin deficient rodents.

Robertson AS, Majchrzak MJ, Smith CM, Gagnon RC, Devidze N, Banks GB, Little SC, Nabbie F, Bounous DI, DiPiero J, Jacobsen LK, Bristow LJ, Ahlijanian MK, Stimpson SA.

Neuromuscul Disord. 2017 Jul;27(7):635-645. doi: 10.1016/j.nmd.2017.05.009. Epub 2017 May 12.

11.
12.

Cytoglobin regulates blood pressure and vascular tone through nitric oxide metabolism in the vascular wall.

Liu X, El-Mahdy MA, Boslett J, Varadharaj S, Hemann C, Abdelghany TM, Ismail RS, Little SC, Zhou D, Thuy LT, Kawada N, Zweier JL.

Nat Commun. 2017 Apr 10;8:14807. doi: 10.1038/ncomms14807.

13.

Discovery of metabolic resistance to neonicotinoids in green peach aphids (Myzus persicae) in Australia.

de Little SC, Edwards O, van Rooyen AR, Weeks A, Umina PA.

Pest Manag Sci. 2017 Aug;73(8):1611-1617. doi: 10.1002/ps.4495. Epub 2017 Jan 30.

PMID:
27888606
14.

Corrigendum: Independent and coordinate trafficking of single Drosophila germ plasm mRNAs.

Little SC, Sinsimer KS, Lee JJ, Wieschaus EF, Gavis ER.

Nat Cell Biol. 2016 Mar;18(3):347. doi: 10.1038/ncb3317. No abstract available.

PMID:
26911912
15.

Rationally engineered Troponin C modulates in vivo cardiac function and performance in health and disease.

Shettigar V, Zhang B, Little SC, Salhi HE, Hansen BJ, Li N, Zhang J, Roof SR, Ho HT, Brunello L, Lerch JK, Weisleder N, Fedorov VV, Accornero F, Rafael-Fortney JA, Gyorke S, Janssen PM, Biesiadecki BJ, Ziolo MT, Davis JP.

Nat Commun. 2016 Feb 24;7:10794. doi: 10.1038/ncomms10794.

16.

Designing proteins to combat disease: Cardiac troponin C as an example.

Davis JP, Shettigar V, Tikunova SB, Little SC, Liu B, Siddiqui JK, Janssen PM, Ziolo MT, Walton SD.

Arch Biochem Biophys. 2016 Jul 1;601:4-10. doi: 10.1016/j.abb.2016.02.007. Epub 2016 Feb 18. Review.

17.

Only accessible information is useful: insights from gradient-mediated patterning.

Tikhonov M, Little SC, Gregor T.

R Soc Open Sci. 2015 Nov 25;2(11):150486. doi: 10.1098/rsos.150486. eCollection 2015 Nov.

18.

Protein phosphatase 2A regulatory subunit B56α limits phosphatase activity in the heart.

Little SC, Curran J, Makara MA, Kline CF, Ho HT, Xu Z, Wu X, Polina I, Musa H, Meadows AM, Carnes CA, Biesiadecki BJ, Davis JP, Weisleder N, Györke S, Wehrens XH, Hund TJ, Mohler PJ.

Sci Signal. 2015 Jul 21;8(386):ra72. doi: 10.1126/scisignal.aaa5876.

19.

Independent and coordinate trafficking of single Drosophila germ plasm mRNAs.

Little SC, Sinsimer KS, Lee JJ, Wieschaus EF, Gavis ER.

Nat Cell Biol. 2015 May;17(5):558-68. doi: 10.1038/ncb3143. Epub 2015 Apr 6. Erratum in: Nat Cell Biol. 2016 Mar;18(3):347.

20.

Eps15 Homology Domain-containing Protein 3 Regulates Cardiac T-type Ca2+ Channel Targeting and Function in the Atria.

Curran J, Musa H, Kline CF, Makara MA, Little SC, Higgins JD, Hund TJ, Band H, Mohler PJ.

J Biol Chem. 2015 May 8;290(19):12210-21. doi: 10.1074/jbc.M115.646893. Epub 2015 Mar 30.

21.

Dysfunction in the βII spectrin-dependent cytoskeleton underlies human arrhythmia.

Smith SA, Sturm AC, Curran J, Kline CF, Little SC, Bonilla IM, Long VP, Makara M, Polina I, Hughes LD, Webb TR, Wei Z, Wright P, Voigt N, Bhakta D, Spoonamore KG, Zhang C, Weiss R, Binkley PF, Janssen PM, Kilic A, Higgins RS, Sun M, Ma J, Dobrev D, Zhang M, Carnes CA, Vatta M, Rasband MN, Hund TJ, Mohler PJ.

Circulation. 2015 Feb 24;131(8):695-708. doi: 10.1161/CIRCULATIONAHA.114.013708. Epub 2015 Jan 28.

22.

Obligatory role of neuronal nitric oxide synthase in the heart's antioxidant adaptation with exercise.

Roof SR, Ho HT, Little SC, Ostler JE, Brundage EA, Periasamy M, Villamena FA, Györke S, Biesiadecki BJ, Heymes C, Houser SR, Davis JP, Ziolo MT.

J Mol Cell Cardiol. 2015 Apr;81:54-61. doi: 10.1016/j.yjmcc.2015.01.003. Epub 2015 Jan 14.

23.

Ankyrin-G coordinates intercalated disc signaling platform to regulate cardiac excitability in vivo.

Makara MA, Curran J, Little SC, Musa H, Polina I, Smith SA, Wright PJ, Unudurthi SD, Snyder J, Bennett V, Hund TJ, Mohler PJ.

Circ Res. 2014 Nov 7;115(11):929-38. doi: 10.1161/CIRCRESAHA.115.305154. Epub 2014 Sep 19.

24.

The embryo as a laboratory: quantifying transcription in Drosophila.

Gregor T, Garcia HG, Little SC.

Trends Genet. 2014 Aug;30(8):364-75. doi: 10.1016/j.tig.2014.06.002. Epub 2014 Jul 6. Review.

25.

Maternal origins of developmental reproducibility.

Petkova MD, Little SC, Liu F, Gregor T.

Curr Biol. 2014 Jun 2;24(11):1283-8. doi: 10.1016/j.cub.2014.04.028. Epub 2014 May 22.

26.

EHD3-dependent endosome pathway regulates cardiac membrane excitability and physiology.

Curran J, Makara MA, Little SC, Musa H, Liu B, Wu X, Polina I, Alecusan JS, Wright P, Li J, Billman GE, Boyden PA, Gyorke S, Band H, Hund TJ, Mohler PJ.

Circ Res. 2014 Jun 20;115(1):68-78. doi: 10.1161/CIRCRESAHA.115.304149. Epub 2014 Apr 23.

27.

Combined troponin I Ser-150 and Ser-23/24 phosphorylation sustains thin filament Ca(2+) sensitivity and accelerates deactivation in an acidic environment.

Nixon BR, Walton SD, Zhang B, Brundage EA, Little SC, Ziolo MT, Davis JP, Biesiadecki BJ.

J Mol Cell Cardiol. 2014 Jul;72:177-85. doi: 10.1016/j.yjmcc.2014.03.010. Epub 2014 Mar 19.

28.

TRPM4 modulates sinus node diastolic depolarization.

Little SC, Mohler PJ.

Heart Rhythm. 2013 Nov;10(11):1690-1. doi: 10.1016/j.hrthm.2013.08.026. Epub 2013 Aug 26. No abstract available.

PMID:
23988696
29.

Environmental flows can reduce the encroachment of terrestrial vegetation into river channels: a systematic literature review.

Miller KA, Webb JA, de Little SC, Stewardson MJ.

Environ Manage. 2013 Nov;52(5):1202-12. doi: 10.1007/s00267-013-0147-0. Epub 2013 Aug 17. Review.

30.

Precise developmental gene expression arises from globally stochastic transcriptional activity.

Little SC, Tikhonov M, Gregor T.

Cell. 2013 Aug 15;154(4):789-800. doi: 10.1016/j.cell.2013.07.025.

31.

Sorting sloppy Sonic.

Little SC, Gregor T.

Cell. 2013 Apr 25;153(3):509-10. doi: 10.1016/j.cell.2013.04.021.

32.

Molecular mechanisms underlying cardiac protein phosphatase 2A regulation in heart.

DeGrande ST, Little SC, Nixon DJ, Wright P, Snyder J, Dun W, Murphy N, Kilic A, Higgins R, Binkley PF, Boyden PA, Carnes CA, Anderson ME, Hund TJ, Mohler PJ.

J Biol Chem. 2013 Jan 11;288(2):1032-46. doi: 10.1074/jbc.M112.426957. Epub 2012 Nov 30.

33.

The rates of Ca2+ dissociation and cross-bridge detachment from ventricular myofibrils as reported by a fluorescent cardiac troponin C.

Little SC, Biesiadecki BJ, Kilic A, Higgins RS, Janssen PM, Davis JP.

J Biol Chem. 2012 Aug 10;287(33):27930-40. doi: 10.1074/jbc.M111.337295. Epub 2012 Jun 20.

34.

Nuances in the management of rhinophyma.

Little SC, Stucker FJ, Compton A, Park SS.

Facial Plast Surg. 2012 Apr;28(2):231-7. doi: 10.1055/s-0032-1309304. Epub 2012 May 6.

PMID:
22562574
35.

AMP-activated protein kinase phosphorylates cardiac troponin I at Ser-150 to increase myofilament calcium sensitivity and blunt PKA-dependent function.

Nixon BR, Thawornkaiwong A, Jin J, Brundage EA, Little SC, Davis JP, Solaro RJ, Biesiadecki BJ.

J Biol Chem. 2012 Jun 1;287(23):19136-47. doi: 10.1074/jbc.M111.323048. Epub 2012 Apr 6.

36.

Experimental comparison of aerial larvicides and habitat modification for controlling disease-carrying Aedes vigilax mosquitoes.

de Little SC, Williamson GJ, Bowman DM, Whelan PI, Brook BW, Bradshaw CJ.

Pest Manag Sci. 2012 May;68(5):709-17. doi: 10.1002/ps.2317. Epub 2011 Nov 10.

PMID:
22076747
37.

Measurement of calcium dissociation rates from troponin C in rigor skeletal myofibrils.

Little SC, Tikunova SB, Norman C, Swartz DR, Davis JP.

Front Physiol. 2011 Oct 11;2:70. doi: 10.3389/fphys.2011.00070. eCollection 2011.

38.

Shifting patterns: merging molecules, morphogens, motility, and methodology.

Little SC, Wieschaus EF.

Dev Cell. 2011 Jul 19;21(1):2-4. doi: 10.1016/j.devcel.2011.06.003.

39.

The formation of the Bicoid morphogen gradient requires protein movement from anteriorly localized mRNA.

Little SC, Tkačik G, Kneeland TB, Wieschaus EF, Gregor T.

PLoS Biol. 2011 Mar;9(3):e1000596. doi: 10.1371/journal.pbio.1000596. Epub 2011 Mar 1.

40.

Effect of calcium-sensitizing mutations on calcium binding and exchange with troponin C in increasingly complex biochemical systems.

Tikunova SB, Liu B, Swindle N, Little SC, Gomes AV, Swartz DR, Davis JP.

Biochemistry. 2010 Mar 9;49(9):1975-84. doi: 10.1021/bi901867s.

41.

The fibrodysplasia ossificans progressiva R206H ACVR1 mutation activates BMP-independent chondrogenesis and zebrafish embryo ventralization.

Shen Q, Little SC, Xu M, Haupt J, Ast C, Katagiri T, Mundlos S, Seemann P, Kaplan FS, Mullins MC, Shore EM.

J Clin Invest. 2009 Nov;119(11):3462-72. doi: 10.1172/JCI37412. Epub 2009 Oct 12.

42.

Quantifying the drivers of larval density patterns in two tropical mosquito species to maximize control efficiency.

De Little SC, Bowman DM, Whelan PI, Brook BW, Bradshaw CJ.

Environ Entomol. 2009 Aug;38(4):1013-21.

PMID:
19689879
43.

Complications with forehead flaps in nasal reconstruction.

Little SC, Hughley BB, Park SS.

Laryngoscope. 2009 Jun;119(6):1093-9. doi: 10.1002/lary.20243.

PMID:
19418536
44.

Bone morphogenetic protein heterodimers assemble heteromeric type I receptor complexes to pattern the dorsoventral axis.

Little SC, Mullins MC.

Nat Cell Biol. 2009 May;11(5):637-43. doi: 10.1038/ncb1870. Epub 2009 Apr 19.

45.

Dual action of TGF-beta1 on nasal-polyp derived fibroblasts.

Little SC, Early SB, Woodard CR, Shonka DC Jr, Han JK, Borish L, Steinke JW.

Laryngoscope. 2008 Feb;118(2):320-4.

PMID:
18090870
46.
47.

Small cell carcinoma of the submandibular gland: a rare small round blue cell tumor.

Walters DM, Little SC, Hessler RB, Gourin CG.

Am J Otolaryngol. 2007 Mar-Apr;28(2):118-21.

PMID:
17362818
48.

Radiographic classification of temporal bone fractures: clinical predictability using a new system.

Little SC, Kesser BW.

Arch Otolaryngol Head Neck Surg. 2006 Dec;132(12):1300-4.

PMID:
17178939
49.

Extracellular modulation of BMP activity in patterning the dorsoventral axis.

Little SC, Mullins MC.

Birth Defects Res C Embryo Today. 2006 Sep;78(3):224-42. Review.

PMID:
17061292
50.

Twisted gastrulation promotes BMP signaling in zebrafish dorsal-ventral axial patterning.

Little SC, Mullins MC.

Development. 2004 Dec;131(23):5825-35. Epub 2004 Nov 3.

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