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Items: 1 to 50 of 328

1.

Electronically delivered interventions to reduce antibiotic prescribing for respiratory infections in primary care: cluster RCT using electronic health records and cohort study.

Gulliford MC, Juszczyk D, Prevost AT, Soames J, McDermott L, Sultana K, Wright M, Fox R, Hay AD, Little P, Moore M, Yardley L, Ashworth M, Charlton J.

Health Technol Assess. 2019 Mar;23(11):1-70. doi: 10.3310/hta23110.

2.

Parental and clinician agreement of illness severity in children with RTIs: secondary analysis of data from a prospective cohort study.

van der Werf ET, Redmond NM, Turnbull S, Thornton H, Thompson M, Little P, Peters TJ, Blair PS, Hay AD.

Br J Gen Pract. 2019 Mar 11. pii: bjgp19X701837. doi: 10.3399/bjgp19X701837. [Epub ahead of print]

PMID:
30858333
3.

Antibiotic Prescribing for Acute Respiratory Tract Infections 12 Months After Communication and CRP Training: A Randomized Trial.

Little P, Stuart B, Francis N, Douglas E, Tonkin-Crine S, Anthierens S, Cals JWL, Melbye H, Santer M, Moore M, Coenen S, Butler CC, Hood K, Kelson M, Godycki-Cwirko M, Mierzecki A, Torres A, Llor C, Davies M, Mullee M, O'Reilly G, van der Velden A, Geraghty AWA, Goossens H, Verheij T, Yardley L; GRACE consortium.

Ann Fam Med. 2019 Mar;17(2):125-132. doi: 10.1370/afm.2356.

4.

Subacute fatigue in primary care - two sides of the story.

Hulme K, Little P, Burrows A, Julia A, Moss-Morris R.

Br J Health Psychol. 2019 Mar 8. doi: 10.1111/bjhp.12361. [Epub ahead of print]

PMID:
30848557
5.

Renewed: Protocol for a randomised controlled trial of a digital intervention to support quality of life in cancer survivors.

Krusche A, Bradbury K, Corbett T, Barnett J, Stuart B, Yao GL, Bacon R, Böhning D, Cheetham-Blake T, Eccles D, Foster C, Geraghty AWA, Leydon G, Müller A, Neal RD, Osborne R, Rathod S, Richardson A, Sharman G, Summers K, Watson E, Wilde L, Wilkinson C, Yardley L, Little P.

BMJ Open. 2019 Mar 1;9(3):e024862. doi: 10.1136/bmjopen-2018-024862.

6.

Effectiveness and safety of electronically delivered prescribing feedback and decision support on antibiotic use for respiratory illness in primary care: REDUCE cluster randomised trial.

Gulliford MC, Prevost AT, Charlton J, Juszczyk D, Soames J, McDermott L, Sultana K, Wright M, Fox R, Hay AD, Little P, Moore MV, Yardley L, Ashworth M.

BMJ. 2019 Feb 12;364:l236. doi: 10.1136/bmj.l236.

7.

COSUTI: a protocol for the development of a core outcome set (COS) for interventions for the treatment of uncomplicated urinary tract infection (UTI) in adults.

Duane S, Vellinga A, Murphy AW, Cormican M, Smyth A, Healy P, Moore M, Little P, Devane D.

Trials. 2019 Feb 7;20(1):106. doi: 10.1186/s13063-019-3194-x.

8.

The impact of the national action plan on the epidemiology of antibiotic resistance among 352,238 isolates in a teaching hospital in China from 2015 to 2018.

Wang S, Hu YJ, Little P, Wang Y, Chang Q, Zhou X, Moore M, Harwell JI.

Antimicrob Resist Infect Control. 2019 Jan 29;8:22. doi: 10.1186/s13756-019-0473-y. eCollection 2019.

9.

Complementary medicine use, views, and experiences: a national survey in England.

Sharp D, Lorenc A, Morris R, Feder G, Little P, Hollinghurst S, Mercer SW, MacPherson H.

BJGP Open. 2018 Nov 14;2(4):bjgpopen18X101614. doi: 10.3399/bjgpopen18X101614. eCollection 2018 Dec.

10.

Delayed antibiotic prescribing for respiratory tract infections: protocol of an individual patient data meta-analysis.

Stuart B, Hounkpatin H, Becque T, Yao G, Zhu S, Alonso-Coello P, Altiner A, Arroll B, Böhning D, Bostock J, Bucher HCC, de la Poza M, Francis NA, Gillespie D, Hay AD, Kenealy T, Löffler C, Mas-Dalmau G, Muñoz L, Samuel K, Moore M, Little P.

BMJ Open. 2019 Jan 21;9(1):e026925. doi: 10.1136/bmjopen-2018-026925.

11.

The International Collaborative on Fatigue Following Infection (COFFI).

Katz BZ, Collin SM, Murphy G, Moss-Morris R, Wyller VB, Wensaas KA, Hautvast JLA, Bleeker-Rovers CP, Vollmer-Conna U, Buchwald D, Taylor R, Little P, Crawley E, White PD, Lloyd A.

Fatigue. 2018;6(2):106-121. doi: 10.1080/21641846.2018.1426086. Epub 2018 Jan 19.

12.

The Prognostic Significance of Low-Frequency Somatic Mutations in Metastatic Cutaneous Melanoma.

Zhao X, Little P, Hoyle AP, Pegna GJ, Hayward MC, Ivanova A, Parker JS, Marron DL, Soloway MG, Jo H, Salazar AH, Papakonstantinou MP, Bouchard DM, Jefferys SR, Hoadley KA, Ollila DW, Frank JS, Thomas NE, Googe PB, Ezzell AJ, Collichio FA, Lee CB, Earp HS, Sharpless NE, Hugo W, Wilmott JS, Quek C, Waddell N, Johansson PA, Thompson JF, Hayward NK, Mann GJ, Lo RS, Johnson DB, Scolyer RA, Hayes DN, Moschos SJ.

Front Oncol. 2019 Jan 4;8:584. doi: 10.3389/fonc.2018.00584. eCollection 2018.

13.

Management strategies for chronic rhinosinusitis: a qualitative study of GP and ENT specialist views of current practice in the UK.

Vennik J, Eyles C, Thomas M, Hopkins C, Little P, Blackshaw H, Schilder A, Boardman J, Philpott CM.

BMJ Open. 2018 Dec 19;8(12):e022643. doi: 10.1136/bmjopen-2018-022643.

14.

Practice variation in the use of tests in UK primary care: a retrospective analysis of 16 million tests performed over 3.3 million patient years in 2015/16.

O'Sullivan JW, Stevens S, Oke J, Hobbs FDR, Salisbury C, Little P, Goldacre B, Bankhead C, Aronson JK, Heneghan C, Perera R.

BMC Med. 2018 Dec 20;16(1):229. doi: 10.1186/s12916-018-1217-1.

15.

Temporal trends in use of tests in UK primary care, 2000-15: retrospective analysis of 250 million tests.

O'Sullivan JW, Stevens S, Hobbs FDR, Salisbury C, Little P, Goldacre B, Bankhead C, Aronson JK, Perera R, Heneghan C.

BMJ. 2018 Nov 28;363:k4666. doi: 10.1136/bmj.k4666. Erratum in: BMJ. 2019 Jan 29;364:l444.

16.

The elicitation and management of multiple health concerns in GP consultations.

Stuart B, Leydon G, Woods C, Gennery E, Elsey C, Summers R, Stevenson F, Chew-Graham C, Barnes R, Drew P, Moore M, Little P.

Patient Educ Couns. 2018 Nov 14. pii: S0738-3991(18)30372-0. doi: 10.1016/j.pec.2018.11.009. [Epub ahead of print]

17.

'Trying to put a square peg into a round hole': a qualitative study of healthcare professionals' views of integrating complementary medicine into primary care for musculoskeletal and mental health comorbidity.

Sharp D, Lorenc A, Feder G, Little P, Hollinghurst S, Mercer S, MacPherson H.

BMC Complement Altern Med. 2018 Oct 29;18(1):290. doi: 10.1186/s12906-018-2349-8.

18.

Adding emollient bath additives to standard eczema management for children with eczema: the BATHE RCT.

Santer M, Rumsby K, Ridd MJ, Francis NA, Stuart B, Chorozoglou M, Roberts A, Liddiard L, Nollett C, Hooper J, Prude M, Wood W, Thomas-Jones E, Becque T, Thomas KS, Williams HC, Little P.

Health Technol Assess. 2018 Oct;22(57):1-116. doi: 10.3310/hta22570.

19.

Feasibility of weekly participant-reported data collection in a pragmatic randomised controlled trial in primary care: experiences from the BATHE trial (Bath Additives for the Treatment of cHildhood Eczema).

Stuart B, Rumsby K, Santer M, Ridd MJ, Francis NA, Chorozoglou M, Spreadbury C, Steele M, Nollett C, Liddiard L, Prude M, Hooper J, Thomas-Jones E, Roberts A, Thomas KS, Williams HC, Little P.

Trials. 2018 Oct 24;19(1):582. doi: 10.1186/s13063-018-2962-3.

20.

Scoping review of systematic reviews of complementary medicine for musculoskeletal and mental health conditions.

Lorenc A, Feder G, MacPherson H, Little P, Mercer SW, Sharp D.

BMJ Open. 2018 Oct 15;8(10):e020222. doi: 10.1136/bmjopen-2017-020222.

21.

OPtimising Treatment for MIld Systolic hypertension in the Elderly (OPTiMISE): protocol for a randomised controlled non-inferiority trial.

Sheppard JP, Burt J, Lown M, Temple E, Benson J, Ford GA, Heneghan C, Hobbs FDR, Jowett S, Little P, Mant J, Mollison J, Nickless A, Ogburn E, Payne R, Williams M, Yu LM, McManus RJ.

BMJ Open. 2018 Oct 4;8(9):e022930. doi: 10.1136/bmjopen-2018-022930.

22.

Multicentred randomised controlled trial of an augmented exercise referral scheme using web-based behavioural support in individuals with metabolic, musculoskeletal and mental health conditions: protocol for the e-coachER trial.

Ingram W, Webb D, Taylor RS, Anokye N, Yardley L, Jolly K, Mutrie N, Campbell JL, Dean SG, Greaves C, Steele M, Lambert JD, McAdam C, Jane B, King J, Jones RB, Little P, Woolf A, Erwin J, Charles N, Terry RH, Taylor AH; Trial Steering Committee.

BMJ Open. 2018 Sep 21;8(9):e022382. doi: 10.1136/bmjopen-2018-022382.

23.

Impact of antibiotics for children presenting to general practice with cough on adverse outcomes: secondary analysis from a multicentre prospective cohort study.

Redmond NM, Turnbull S, Stuart B, Thornton HV, Christensen H, Blair PS, Delaney BC, Thompson M, Peters TJ, Hay AD, Little P.

Br J Gen Pract. 2018 Oct;68(675):e682-e693. doi: 10.3399/bjgp18X698873. Epub 2018 Sep 10. Erratum in: Br J Gen Pract. 2019 Jan;69(678):14.

24.

Cost-effectiveness of internet-based training for primary care clinicians on antibiotic prescribing for acute respiratory tract infections in Europe.

Oppong R, Smith RD, Little P, Verheij T, Butler CC, Goossens H, Coenen S, Jowett S, Roberts TE, Achana F, Stuart B, Coast J.

J Antimicrob Chemother. 2018 Nov 1;73(11):3189-3198. doi: 10.1093/jac/dky309.

PMID:
30165522
25.

Screening for Atrial Fibrillation Using Economical and Accurate Technology (From the SAFETY Study).

Lown M, Yue AM, Shah BN, Corbett SJ, Lewith G, Stuart B, Garrard J, Brown M, Little P, Moore M.

Am J Cardiol. 2018 Oct 15;122(8):1339-1344. doi: 10.1016/j.amjcard.2018.07.003. Epub 2018 Jul 19.

PMID:
30131106
26.

Clinical relevance of bacterial resistance in lower respiratory tract infection in primary care: secondary analysis of a multicentre European trial.

Teepe J, Broekhuizen BD, Goossens H, Hordijk PM, Loens K, Lammens C, Ieven M, Little P, Butler CC, Coenen S, Godycki-Cwirko M, Henriques-Normark B, Verheij TJ; GRACE consortium.

Br J Gen Pract. 2018 Sep;68(674):e627-e632. doi: 10.3399/bjgp18X698333. Epub 2018 Jul 30.

PMID:
30061194
27.

Continuous low-dose antibiotic prophylaxis for adults with repeated urinary tract infections (AnTIC): a randomised, open-label trial.

Fisher H, Oluboyede Y, Chadwick T, Abdel-Fattah M, Brennand C, Fader M, Harrison S, Hilton P, Larcombe J, Little P, McClurg D, McColl E, N'Dow J, Ternent L, Thiruchelvam N, Timoney A, Vale L, Walton K, von Wilamowitz-Moellendorff A, Wilkinson J, Wood R, Pickard R.

Lancet Infect Dis. 2018 Sep;18(9):957-968. doi: 10.1016/S1473-3099(18)30279-2. Epub 2018 Jun 28. Erratum in: Lancet Infect Dis. 2018 Sep;18(9):941.

28.

Antivirals for influenza-Like Illness? A randomised Controlled trial of Clinical and Cost effectiveness in primary CarE (ALIC4 E): the ALIC4 E protocol.

Bongard E, van der Velden AW, Cook J, Saville B, Beutels P, Munck Aabenhus R, Brugman C, Chlabicz S, Coenen S, Colliers A, Davies M, De Paor M, De Sutter A, Francis NA, Glinz D, Godycki-Ćwirko M, Goossens H, Holmes J, Ieven M, de Jong M, Lindbaek M, Little P, Martinón-Torres F, Moragas A, Pauer J, Pfeiferová M, Radzeviciene-Jurgute R, Sundvall PD, Torres A, Touboul P, Varthalis D, Verheij T, Butler CC.

BMJ Open. 2018 Jul 12;8(7):e021032. doi: 10.1136/bmjopen-2017-021032.

29.

LCCC 1025: a phase II study of everolimus, trastuzumab, and vinorelbine to treat progressive HER2-positive breast cancer brain metastases.

Van Swearingen AED, Siegel MB, Deal AM, Sambade MJ, Hoyle A, Hayes DN, Jo H, Little P, Dees EC, Muss H, Jolly T, Zagar TM, Patel N, Miller CR, Parker JS, Smith JK, Fisher J, Shah N, Nabell L, Nanda R, Dillon P, Abramson V, Carey LA, Anders CK.

Breast Cancer Res Treat. 2018 Oct;171(3):637-648. doi: 10.1007/s10549-018-4852-5. Epub 2018 Jun 25.

PMID:
29938395
30.

Do patients actually do what we ask: patient fidelity and persistence to the Targets and Self-Management for the Control of Blood Pressure in Stroke and at Risk Groups blood pressure self-management intervention.

Schwartz CL, Seyed-Safi A, Haque S, Bray EP, Greenfield S, Hobbs FDR, Little P, Mant J, Williams B, Mcmanus RJ.

J Hypertens. 2018 Aug;36(8):1753-1761. doi: 10.1097/HJH.0000000000001738.

PMID:
29889157
31.

Knowledge, Attitude, and Practice with Respect to Antibiotic Use among Chinese Medical Students: A Multicentre Cross-Sectional Study.

Hu Y, Wang X, Tucker JD, Little P, Moore M, Fukuda K, Zhou X.

Int J Environ Res Public Health. 2018 Jun 4;15(6). pii: E1165. doi: 10.3390/ijerph15061165.

32.

Early use of Antibiotics for at Risk CHildren with InfluEnza (ARCHIE): protocol for a double-blind, randomised, placebo-controlled trial.

Wang K, Carver T, Tonner S, Semple MG, Hay AD, Moore M, Little P, Butler C, Farmer A, Perera R, Yu LM, Mallett S, Wolstenholme J, Harnden A.

BMJ Open. 2018 May 16;8(5):e021144. doi: 10.1136/bmjopen-2017-021144.

33.

Continuous low-dose antibiotic prophylaxis to prevent urinary tract infection in adults who perform clean intermittent self-catheterisation: the AnTIC RCT.

Pickard R, Chadwick T, Oluboyede Y, Brennand C, von Wilamowitz-Moellendorff A, McClurg D, Wilkinson J, Ternent L, Fisher H, Walton K, McColl E, Vale L, Wood R, Abdel-Fattah M, Hilton P, Fader M, Harrison S, Larcombe J, Little P, Timoney A, N'Dow J, Armstrong H, Morris N, Walker K, Thiruchelvam N.

Health Technol Assess. 2018 May;22(24):1-102. doi: 10.3310/hta22240.

34.

A trial like ALIC4E: why design a platform, response-adaptive, open, randomised controlled trial of antivirals for influenza-like illness?

Butler CC, Coenen S, Saville BR, Cook J, van der Velden A, Homes J, de Jong M, Little P, Goossens H, Beutels P, Ieven M, Francis N, Moons P, Bongard E, Verheij T.

ERJ Open Res. 2018 May 8;4(2). pii: 00046-2018. doi: 10.1183/23120541.00046-2018. eCollection 2018 Apr.

35.

Analytical performance of a platform for point-of-care CRP testing in adults consulting for lower respiratory tract infection in primary care.

Matheeussen V, Van Hoof V, Loens K, Lammens C, Vanderstraeten A, Coenen S, Butler CC, Little P, Verheij TJM, Goossens H, Ieven M; GRACE consortium.

Eur J Clin Microbiol Infect Dis. 2018 Jul;37(7):1319-1323. doi: 10.1007/s10096-018-3253-3. Epub 2018 May 10.

PMID:
29744764
36.

Qualitative process study to explore the perceived burdens and benefits of a digital intervention for self-managing high blood pressure in Primary Care in the UK.

Morton K, Dennison L, Bradbury K, Band RJ, May C, Raftery J, Little P, McManus RJ, Yardley L.

BMJ Open. 2018 May 8;8(5):e020843. doi: 10.1136/bmjopen-2017-020843.

37.

Emollient bath additives for the treatment of childhood eczema (BATHE): multicentre pragmatic parallel group randomised controlled trial of clinical and cost effectiveness.

Santer M, Ridd MJ, Francis NA, Stuart B, Rumsby K, Chorozoglou M, Becque T, Roberts A, Liddiard L, Nollett C, Hooper J, Prude M, Wood W, Thomas KS, Thomas-Jones E, Williams HC, Little P.

BMJ. 2018 May 3;361:k1332. doi: 10.1136/bmj.k1332.

38.

Using the Person-Based Approach to optimise a digital intervention for the management of hypertension.

Bradbury K, Morton K, Band R, van Woezik A, Grist R, McManus RJ, Little P, Yardley L.

PLoS One. 2018 May 3;13(5):e0196868. doi: 10.1371/journal.pone.0196868. eCollection 2018.

39.

Economic analysis of oral dexamethasone for symptom relief of sore throat: the UK TOAST study.

Burns RM, Wolstenholme J, Jawad S, Williams N, Thompson M, Perera R, Hay AD, Heneghan C, Little P, Moore M, Hayward G; TOAST Trial Investigators.

BMJ Open. 2018 Apr 28;8(4):e019184. doi: 10.1136/bmjopen-2017-019184. Erratum in: BMJ Open. 2019 Feb 19;9(2):e019184corr1.

40.

Exploring cancer survivors' views of health behaviour change: "Where do you start, where do you stop with everything?"

Corbett T, Cheetham T, Müller AM, Slodkowska-Barabasz J, Wilde L, Krusche A, Richardson A, Foster C, Watson E, Little P, Yardley L, Bradbury K.

Psychooncology. 2018 Jul;27(7):1816-1824. doi: 10.1002/pon.4732. Epub 2018 May 1.

PMID:
29645327
41.

Development of a prediction tool for patients presenting with acute cough in primary care: a prognostic study spanning six European countries.

Bruyndonckx R, Hens N, Verheij TJ, Aerts M, Ieven M, Butler CC, Little P, Goossens H, Coenen S; GRACE project group.

Br J Gen Pract. 2018 May;68(670):e342-e350. doi: 10.3399/bjgp18X695789. Epub 2018 Apr 9.

PMID:
29632005
42.

Findings from a feasibility study to improve GP elicitation of patient concerns in UK general practice consultations.

Leydon GM, Stuart B, Summers RH, Little P, Ekberg S, Stevenson F, Chew-Graham CA, Brindle L, Heritage J, Drew P, Moore MV.

Patient Educ Couns. 2018 Aug;101(8):1394-1402. doi: 10.1016/j.pec.2018.03.009. Epub 2018 Mar 23.

PMID:
29627268
43.

Response to: 'Screening for atrial fibrillation in hospitalised geriatric patients' by Tavernier et al.

Lown M, Shah BN, Corbett SJ, Yue A, Little P, Moore M.

Heart. 2018 Apr;104(7):624. doi: 10.1136/heartjnl-2017-312672. No abstract available.

PMID:
29535216
44.

Multimorbidity and Socioeconomic Deprivation in Primary Care Consultations.

Mercer SW, Zhou Y, Humphris GM, McConnachie A, Bakhshi A, Bikker A, Higgins M, Little P, Fitzpatrick B, Watt GCM.

Ann Fam Med. 2018 Mar;16(2):127-131. doi: 10.1370/afm.2202.

45.

The association between copy number aberration, DNA methylation and gene expression in tumor samples.

Sun W, Bunn P, Jin C, Little P, Zhabotynsky V, Perou CM, Hayes DN, Chen M, Lin DY.

Nucleic Acids Res. 2018 Apr 6;46(6):3009-3018. doi: 10.1093/nar/gky131.

46.

Using an internet intervention to support self-management of low back pain in primary care: findings from a randomised controlled feasibility trial (SupportBack).

Geraghty AWA, Stanford R, Stuart B, Little P, Roberts LC, Foster NE, Hill JC, Hay EM, Turner D, Malakan W, Leigh L, Yardley L.

BMJ Open. 2018 Mar 9;8(3):e016768. doi: 10.1136/bmjopen-2017-016768.

47.

Point-of-care urine culture for managing urinary tract infection in primary care: a randomised controlled trial of clinical and cost-effectiveness.

Butler CC, Francis NA, Thomas-Jones E, Longo M, Wootton M, Llor C, Little P, Moore M, Bates J, Pickles T, Kirby N, Gillespie D, Rumsby K, Brugman C, Gal M, Hood K, Verheij T.

Br J Gen Pract. 2018 Apr;68(669):e268-e278. doi: 10.3399/bjgp18X695285. Epub 2018 Feb 26.

PMID:
29483078
48.

Effectiveness of general practitioner online training and an information booklet for parents on antibiotic prescribing for children with respiratory tract infection in primary care: a cluster randomized controlled trial.

Dekker ARJ, Verheij TJM, Broekhuizen BDL, Butler CC, Cals JWL, Francis NA, Little P, Sanders EAM, Yardley L, Zuithoff NPA, van der Velden AW.

J Antimicrob Chemother. 2018 May 1;73(5):1416-1422. doi: 10.1093/jac/dkx542.

PMID:
29438547
49.

What gives rise to clinician gut feeling, its influence on management decisions and its prognostic value for children with RTI in primary care: a prospective cohort study.

Turnbull S, Lucas PJ, Redmond NM, Christensen H, Thornton H, Cabral C, Blair PS, Delaney BC, Thompson M, Little P, Peters TJ, Hay AD.

BMC Fam Pract. 2018 Feb 5;19(1):25. doi: 10.1186/s12875-018-0716-7.

50.

Probiotic capsules and xylitol chewing gum to manage symptoms of pharyngitis: a randomized controlled factorial trial.

Little P, Stuart B, Wingrove Z, Mullee M, Thomas T, Johnson S, Leydon G, Richards-Hall S, Williamson I, Yao L, Zhu S, Moore M.

CMAJ. 2017 Dec 18;189(50):E1543-E1550. doi: 10.1503/cmaj.170599.

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