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Items: 1 to 50 of 72

1.

Persistence of platinum-ammine-DNA adducts in gonads and kidneys of rats and multiple tissues from cancer patients.

Poirier MC, Reed E, Litterst CL, Katz D, Gupta-Burt S.

Cancer Res. 1992 Jan 1;52(1):149-53.

2.

Characterization of the DNA damage recognized by an antiserum elicited against cis-diamminedichloroplatinum (II)-modified DNA.

Reed E, Gupta-Burt S, Litterst CL, Poirier MC.

Carcinogenesis. 1990 Dec;11(12):2117-21.

PMID:
1979937
3.

Metabolic activation of 4-ipomeanol in human lung, primary pulmonary carcinomas, and established human pulmonary carcinoma cell lines.

McLemore TL, Litterst CL, Coudert BP, Liu MC, Hubbard WC, Adelberg S, Czerwinski M, McMahon NA, Eggleston JC, Boyd MR.

J Natl Cancer Inst. 1990 Sep 5;82(17):1420-6.

PMID:
2388294
4.
5.

Profiles of prostaglandin biosynthesis in normal lung and tumor tissue from lung cancer patients.

McLemore TL, Hubbard WC, Litterst CL, Liu MC, Miller S, McMahon NA, Eggleston JC, Boyd MR.

Cancer Res. 1988 Jun 1;48(11):3140-7.

6.
7.

Alterations in plasma pharmacokinetics of cisplatin in tumor-bearing rats.

Litterst CL, Magin R.

Cancer Chemother Pharmacol. 1988;22(1):1-4.

PMID:
3396142
8.

In vivo biochemical indices of nephrotoxicity of platinum analogs tetraplatin, CHIP, and cisplatin in the Fischer 344 rat.

Smith MA, Smith JH, Litterst CL, Copley MP, Uozumi J, Boyd MR.

Fundam Appl Toxicol. 1988 Jan;10(1):62-72.

PMID:
3350230
9.

Comparative toxicity and renal distribution of the platinum analogs tetraplatin, CHIP, and cisplatin at equimolar doses in the Fischer 344 rat.

Smith JH, Smith MA, Litterst CL, Copley MP, Uozumi J, Boyd MR.

Fundam Appl Toxicol. 1988 Jan;10(1):45-61.

PMID:
3350229
10.

Chemical reactions occurring between metal-containing antineoplastic drugs and biological molecules.

Litterst CL.

Pharmacol Ther. 1988;38(2):215-51. Review. No abstract available.

PMID:
3054940
11.

The disposition and metabolism of 2',3'-dideoxycytidine, an in vitro inhibitor of human T-lymphotrophic virus type III infectivity, in mice and monkeys.

Kelley JA, Litterst CL, Roth JS, Vistica DT, Poplack DG, Cooney DA, Nadkarni M, Balis FM, Broder S, Johns DG.

Drug Metab Dispos. 1987 Sep-Oct;15(5):595-601.

PMID:
2891473
12.

cis-Diamminedichloroplatinum (II)-DNA adduct formation in renal, gonadal, and tumor tissues of male and female rats.

Reed E, Litterst CL, Thill CC, Yuspa SH, Poirier MC.

Cancer Res. 1987 Feb 1;47(3):718-22.

13.
14.
15.

Polyclonal antibodies to quantitate cis-diamminedichloroplatinum(II)--DNA adducts in cancer patients and animal models.

Poirier MC, Reed E, Zwelling LA, Ozols RF, Litterst CL, Yuspa SH.

Environ Health Perspect. 1985 Oct;62:89-94.

16.

Physiological model for the pharmacokinetics of cis-dichlorodiammineplatinum (II) (DDP) in the tumored rat.

Farris FF, King FG, Dedrick RL, Litterst CL.

J Pharmacokinet Biopharm. 1985 Feb;13(1):13-39.

PMID:
4040567
17.

Distribution, elimination, metabolism and bioavailability of hexamethylenebisacetamide in rats.

Litterst CL, Roth JS, Kelley JA.

Invest New Drugs. 1985;3(3):263-72.

PMID:
4066220
18.

The effect of cisplatin on renal ATPase activity in vivo and in vitro.

Uozumi J, Litterst CL.

Cancer Chemother Pharmacol. 1985;15(2):93-6.

PMID:
2990752
19.

Cisplatinum: a review, with special reference to cellular and molecular interactions.

Litterst CL.

Agents Actions. 1984 Dec;15(5-6):520-4. Review. No abstract available.

PMID:
6241789
20.

Amelioration of cisplatin-induced nephrotoxicity by the diuretic acetazolamide in F344 rats.

Osman NM, Copley MP, Litterst CL.

Cancer Treat Rep. 1984 Jul-Aug;68(7-8):999-1004.

PMID:
6540145
21.

Interaction of the oncolytic drug, 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea with the mixed-function oxidase system in rats.

Tong S, Hirokata Y, Litterst CL, Gram TE.

Chem Biol Interact. 1984 Apr;49(1-2):105-19.

PMID:
6722931
22.

The disposition and metabolism of tiazofurin in rodents, rabbits, and dogs.

Arnold ST, Jayaram HN, Harper GR, Litterst CL, Malspeis L, DeSouza JJ, Staubus AE, Ahluwalia GS, Wilson YA, Cooney DA.

Drug Metab Dispos. 1984 Mar-Apr;12(2):165-73.

PMID:
6144481
23.

Platinum tissue concentrations following intra-arterial and intravenous cis-diamminedichloroplatinum II in New Zealand white rabbits.

Carlson JA Jr, Litterst CL, Greenberg RA, Day TG Jr, Masterson BJ.

Am J Obstet Gynecol. 1984 Feb 1;148(3):313-7.

PMID:
6538067
24.
25.

Effects of the diuretics mannitol or acetazolamide on nephrotoxicity and physiological disposition of cisplatin in rats.

Osman NM, Copley MP, Litterst CL.

Cancer Chemother Pharmacol. 1984;13(1):58-62.

PMID:
6428763
26.
27.
28.

Platinum concentrations in human glioblastoma multiforme following the use of cisplatin.

Bonnem EM, Litterst CL, Smith FP.

Cancer Treat Rep. 1982 Aug;66(8):1661-3.

PMID:
6286121
29.

Toxicity of free and liposome-encapsulated adriamycin following large volume, short-term intraperitoneal exposure in the rat.

Litterst CL, Sieber SM, Copley M, Parker RJ.

Toxicol Appl Pharmacol. 1982 Jul;64(3):517-28. No abstract available.

PMID:
7135399
30.

Changes in renal handling of platinum in cisplatinum-treated rats following induction of metabolic acidosis or alkalosis.

Bertolero F, Litterst CL.

Res Commun Chem Pathol Pharmacol. 1982 May;36(2):273-85.

PMID:
7201666
31.
32.

Local and systemic toxicity resulting from large-volume ip administration of doxorubicin in the rat.

Litterst CL, Collins JM, Lowe MC, Arnold ST, Powell DM, Guarino AM.

Cancer Treat Rep. 1982 Jan;66(1):157-61.

PMID:
7053251
33.

Adsorption of antineoplastic drugs following large-volume ip administration to rats.

Litterst CL, Torres IJ, Arnold S, McGunagle D, Furner R, Sikic BI, Guarino AM.

Cancer Treat Rep. 1982 Jan;66(1):147-55. No abstract available.

PMID:
7053249
36.

Distribution of adriamycin in mice under conditions of local hyperthermia which improve systemic drug therapy.

Magin RL, Cysyk RL, Litterst CL.

Cancer Treat Rep. 1980 Feb-Mar;64(2-3):203-10.

PMID:
7407753
37.

In vitro hepatic drug metabolism and microsomal enzyme induction in genetically obese rats.

Litterst CL.

Biochem Pharmacol. 1980 Feb;29(3):289-96. No abstract available.

PMID:
7362641
39.

Hepatic cytochrome P-450-dependent metabolism and enzymatic conjugation of foreign compounds in vitamin A-deficient rats.

Siddik ZH, Drew R, Litterst CL, Mimnaugh EG, Sikic BI, Gram TE.

Pharmacology. 1980;21(6):383-90.

PMID:
7220590
40.

Pharmacokinetics and protein binding of cis-dichlorodiammine platinum (II) administered as a one hour or as a twenty hour infusion.

Gullo JJ, Litterst CL, Maguire PJ, Sikic BI, Hoth DF, Woolley PV.

Cancer Chemother Pharmacol. 1980;5(1):21-6.

PMID:
6161715
41.

The distribution of 14C-imipramine in mice bearing Lewis lung carcinoma.

Drew R, Sikic BI, Mimnaugh EG, Litterst CL, Gram TE.

Life Sci. 1979 Nov 19;25(21):1813-20. No abstract available.

PMID:
529988
42.

Disposition and distribution of platinum following parenteral administration of cis-dichlorodiammineplatinum(II) to animals.

Litterst CL, LeRoy AF, Guarino AM.

Cancer Treat Rep. 1979 Sep-Oct;63(9-10):1485-92.

PMID:
498147
43.

Platinate toxicity: past, present, and prospects.

Guarino AM, Miller DS, Arnold ST, Pritchard JB, Davis RD, Urbanek MA, Miller TJ, Litterst CL.

Cancer Treat Rep. 1979 Sep-Oct;63(9-10):1475-83.

PMID:
159127
44.

Lack of correlation between cortisol-induced precocious maturation of the fetal rabbit lung and drug metabolism.

Siddik ZH, Sikic BI, Drew R, Mimnaugh EG, Litterst CL, Gram TE.

Biochem Pharmacol. 1979 Mar 1;28(5):683-5. No abstract available.

PMID:
444254
45.

Pharmacokinetic study of cis-dichlorodiammineplatinum(II) (DDP) in the beagle dog: thermodynamic and kinetic behavior of DDP in a biologic millieu.

LeRoy AF, Lutz RJ, Dedrick RL, Litterst CL, Guarino AM.

Cancer Treat Rep. 1979 Jan;63(1):59-71. No abstract available.

PMID:
421234
46.

In vitro drug metabolism in male and female athymic, nude mice.

Litterst CL, Sikic BI, Mimnaugh EG, Guarino AM, Gram TE.

Life Sci. 1978 May 15;22(19):1723-30. No abstract available.

PMID:
672423
47.

Effect of whole-body hyperthermia on the disposition and metabolism of adriamycin in rabbits.

Mimnaugh EG, Waring RW, Sikic BI, Magin RL, Drew R, Litterst CL, Gram TE, Guarino AM.

Cancer Res. 1978 May;38(5):1420-5. No abstract available.

48.
49.

Transport of model compounds across the peritoneal membrane in the rat.

Torres IJ, Litterst CL, Guarino AM.

Pharmacology. 1978;17(6):330-40.

PMID:
32560
50.

Effect of strain differences and tumor presence on microsomal drug metabolism in the guinea pig: brief communication.

Litterst CL, Mimnaugh EG, Gram TE.

J Natl Cancer Inst. 1977 Dec;59(6):1737-9.

PMID:
200761

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